TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T62276	Glutamate receptor ionotropic NMDA 1	B17VLI	5-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-1,3-dihydro-indol-2-one	Investigative	10498624	C24H26N2O	358.5	C1CN(CCC1CC2=CC=CC=C2)CCC#CC3=CC4=C(C=C3)NC(=O)C4	IC50 = 52000 nM	Poor binder
T62276	Glutamate receptor ionotropic NMDA 1	B3A0EQ	5-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1,3-dihydro-indol-2-one	Investigative	10569480	C23H24N2O	344.4	C1CN(CCC1CC2=CC=CC=C2)CC#CC3=CC4=C(C=C3)NC(=O)C4	IC50 ~ 100000 nM	Poor binder
T62276	Glutamate receptor ionotropic NMDA 1	B3BMG0	6-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1-methyl-1,3-dihydro-benzoimidazol-2-one	Investigative	10737190	C23H25N3O	359.5	CN1C2=C(C=CC(=C2)C#CCN3CCC(CC3)CC4=CC=CC=C4)NC1=O	IC50 ~ 100000 nM	Poor binder
T62276	Glutamate receptor ionotropic NMDA 1	B3Z5VO	5-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-1,3-dihydro-benzoimidazole-2-thione	Investigative	10738253	C23H25N3S	375.5	C1CN(CCC1CC2=CC=CC=C2)CCC#CC3=CC4=C(C=C3)NC(=S)N4	IC50 = 75000 nM	Poor binder
T62276	Glutamate receptor ionotropic NMDA 1	B4E8GX	5-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1H-indole	Investigative	10640029	C23H24N2	328.4	C1CN(CCC1CC2=CC=CC=C2)CC#CC3=CC4=C(C=C3)NC=C4	IC50 ~ 100000 nM	Poor binder
T62276	Glutamate receptor ionotropic NMDA 1	B52VXR	3-(Benzylamino-methyl)-4,6-dichloro-1H-indole-2-carboxylic acid	Investigative	11035463	C17H14Cl2N2O2	349.2	C1=CC=C(C=C1)CNCC2=C(NC3=C2C(=CC(=C3)Cl)Cl)C(=O)O	Ki = 92000 nM	Poor binder
T62276	Glutamate receptor ionotropic NMDA 1	B8EXO0	5-{3-[4-(4-Methoxy-benzyl)-piperidin-1-yl]-prop-1-ynyl}-1,3-dihydro-benzoimidazol-2-one	Investigative	10809482	C23H25N3O2	375.5	COC1=CC=C(C=C1)CC2CCN(CC2)CC#CC3=CC4=C(C=C3)NC(=O)N4	IC50 ~ 100000 nM	Poor binder
T62276	Glutamate receptor ionotropic NMDA 1	B9GBJ2	5-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-1H-indazole	Investigative	10688762	C23H25N3	343.5	C1CN(CCC1CC2=CC=CC=C2)CCC#CC3=CC4=C(C=C3)NN=C4	IC50 = 95000 nM	Poor binder
T62276	Glutamate receptor ionotropic NMDA 1	B9TLB6	5-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1,3-dihydro-benzoimidazole-2-thione	Investigative	10618608	C22H23N3S	361.5	C1CN(CCC1CC2=CC=CC=C2)CC#CC3=CC4=C(C=C3)NC(=S)N4	IC50 ~ 100000 nM	Poor binder
T62276	Glutamate receptor ionotropic NMDA 1	BAG1R8	5-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1H-indazole	Investigative	10758743	C22H23N3	329.4	C1CN(CCC1CC2=CC=CC=C2)CC#CC3=CC4=C(C=C3)NN=C4	IC50 ~ 100000 nM	Poor binder
T62276	Glutamate receptor ionotropic NMDA 1	BBK75O	5-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-1H-indole-2,3-dione	Investigative	10761824	C24H24N2O2	372.5	C1CN(CCC1CC2=CC=CC=C2)CCC#CC3=CC4=C(C=C3)NC(=O)C4=O	IC50 = 57000 nM	Poor binder
T62276	Glutamate receptor ionotropic NMDA 1	BEQ5N6	5-[3-(4-Benzylpiperidino)-1-propynyl]-1H-benzimidazole-2(3H)-one	Investigative	9863010	C22H23N3O	345.4	C1CN(CCC1CC2=CC=CC=C2)CC#CC3=CC4=C(C=C3)NC(=O)N4	IC50 ~ 100000 nM	Poor binder
T62276	Glutamate receptor ionotropic NMDA 1	BFX23V	6-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-3H-benzooxazol-2-one	Investigative	10832383	C23H24N2O2	360.4	C1CN(CCC1CC2=CC=CC=C2)CCC#CC3=CC4=C(C=C3)NC(=O)O4	IC50 ~ 100000 nM	Poor binder
T62276	Glutamate receptor ionotropic NMDA 1	BH89CU	5-(3-(4-Benzylpiperidin-1-yl)prop-1-ynyl)-1-methyl-1H-benzo[d]imidazol-2(3H)-one	Investigative	10760940	C23H25N3O	359.5	CN1C2=C(C=C(C=C2)C#CCN3CCC(CC3)CC4=CC=CC=C4)NC1=O	IC50 = 62000 nM	Poor binder
T62276	Glutamate receptor ionotropic NMDA 1	BN18YB	5-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-1,3-dihydro-benzoimidazol-2-one	Investigative	10784705	C23H25N3O	359.5	C1CN(CCC1CC2=CC=CC=C2)CCC#CC3=CC4=C(C=C3)NC(=O)N4	IC50 ~ 100000 nM	Poor binder
T62276	Glutamate receptor ionotropic NMDA 1	BNOQ51	5-{3-[4-(3-Fluoro-benzyl)-piperidin-1-yl]-prop-1-ynyl}-1,3-dihydro-benzoimidazol-2-one	Investigative	10808704	C22H22FN3O	363.4	C1CN(CCC1CC2=CC(=CC=C2)F)CC#CC3=CC4=C(C=C3)NC(=O)N4	IC50 ~ 100000 nM	Poor binder
T62276	Glutamate receptor ionotropic NMDA 1	BR6MJ2	5-[3-(4-Benzyl-4-hydroxy-piperidin-1-yl)-prop-1-ynyl]-1,3-dihydro-benzoimidazol-2-one	Investigative	10594749	C22H23N3O2	361.4	C1CN(CCC1(CC2=CC=CC=C2)O)CC#CC3=CC4=C(C=C3)NC(=O)N4	IC50 ~ 100000 nM	Poor binder
T62276	Glutamate receptor ionotropic NMDA 1	BSGY48	7-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-4H-benzo[1,4]oxazin-3-one	Investigative	10809420	C24H26N2O2	374.5	C1CN(CCC1CC2=CC=CC=C2)CCC#CC3=CC4=C(C=C3)NC(=O)CO4	IC50 ~ 100000 nM	Poor binder
T62276	Glutamate receptor ionotropic NMDA 1	BY4TU0	5-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1H-benzotriazole	Investigative	10640185	C21H22N4	330.4	C1CN(CCC1CC2=CC=CC=C2)CC#CC3=CC4=NNN=C4C=C3	IC50 ~ 100000 nM	Poor binder
T62276	Glutamate receptor ionotropic NMDA 1	BZ0JN1	5-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-prop-1-ynyl}-1,3-dihydro-benzoimidazol-2-one	Investigative	9998801	C22H22FN3O	363.4	C1CN(CCC1CC2=CC=C(C=C2)F)CC#CC3=CC4=C(C=C3)NC(=O)N4	IC50 ~ 100000 nM	Poor binder
T62276	Glutamate receptor ionotropic NMDA 1	BZ31IB	5-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-1H-benzotriazole	Investigative	10736249	C22H24N4	344.5	C1CN(CCC1CC2=CC=CC=C2)CCC#CC3=CC4=NNN=C4C=C3	IC50 ~ 100000 nM	Poor binder