TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T65019	Matrix metalloproteinase-14	D0G1LL	1607004-34-1	Patented	74221072	C20H22F3N3O3	409.4	C1CC1[C@H](CC2=CC=C(C=C2)C(F)(F)F)C(=O)NC[C@@]3(C(=O)NC(=O)N3)C4CC4	IC50 = 50000 nM	Poor binder
T65019	Matrix metalloproteinase-14	D0N6ZA	US9206139, 4	Patented	74221131	C20H24F3N3O3	411.4	CC(C)[C@H](CC1=CC=C(C=C1)C(F)(F)F)C(=O)NC[C@@]2(C(=O)NC(=O)N2)C3CC3	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B02AMR	(5S)-5-Methyl-5-[[4-[5-[(3-methyl-1,2-oxazol-5-yl)methoxy]pyrimidin-2-yl]piperazin-1-yl]sulfonylmethyl]imidazolidine-2,4-dione	Investigative	73352170	C18H23N7O6S	465.5	CC1=NOC(=C1)COC2=CN=C(N=C2)N3CCN(CC3)S(=O)(=O)C[C@@]4(C(=O)NC(=O)N4)C	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B0BMJ6	Benzyl N-[(4R)-4-[[4-(4-cyano-2-methylphenyl)piperazin-1-yl]sulfonylamino]-5-(hydroxyamino)-5-oxopentyl]carbamate	Investigative	127026888	C25H32N6O6S	544.6	CC1=C(C=CC(=C1)C#N)N2CCN(CC2)S(=O)(=O)N[C@H](CCCNC(=O)OCC3=CC=CC=C3)C(=O)NO	IC50 = 50000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B0D5MH	3-[({2-[4-({[(4s)-4-Methyl-2,5-Dioxoimidazolidin-4-Yl]methyl}sulfonyl)piperazin-1-Yl]pyrimidin-5-Yl}oxy)methyl]benzonitrile	Investigative	71815036	C21H23N7O5S	485.5	C[C@]1(C(=O)NC(=O)N1)CS(=O)(=O)N2CCN(CC2)C3=NC=C(C=N3)OCC4=CC(=CC=C4)C#N	IC50 = 53584 nM	Poor binder
T65019	Matrix metalloproteinase-14	B0HJ9Y	[Phosphono-[4-(trifluoromethyl)anilino]methyl]phosphonic acid	Investigative	72204931	C8H10F3NO6P2	335.11	C1=CC(=CC=C1C(F)(F)F)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B0MUP5	2-(4-Chlorophenoxy)-N-{[(4r)-4-Methyl-2,5-Dioxoimidazolidin-4-Yl]methyl}acetamide	Investigative	86287514	C13H14ClN3O4	311.72	C[C@]1(C(=O)NC(=O)N1)CNC(=O)COC2=CC=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B0U3TW	N-Hydroxy-2-[4-(3,5-dibromobenzyloxy)phenylsulfonyl(methyl)amino]acetamide	Investigative	72714083	C16H16Br2N2O5S	508.2	CN(CC(=O)NO)S(=O)(=O)C1=CC=C(C=C1)OCC2=CC(=CC(=C2)Br)Br	IC50 = 123000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B1DGY0	(R)-3-((S)-1-((S)-2-Methoxy-1-phenylethylamino)-3,3-dimethyl-1-oxobutan-2-ylcarbamoyl)-6-(2-methylbiphenyl-4-YL)hexanoic acid	Investigative	9808181	C35H44N2O5	572.7	CC1=C(C=CC(=C1)CCC[C@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@H](COC)C2=CC=CC=C2)C(C)(C)C)C3=CC=CC=C3	IC50 = 66900 nM	Poor binder
T65019	Matrix metalloproteinase-14	B2GW6F	(P-Tolylamino)methylenediphosphonic acid	Investigative	13738810	C8H13NO6P2	281.14	CC1=CC=C(C=C1)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B2K1NI	(3R)-6-Cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-1,2,4-oxadiazol-5-yl]-N-hydroxyhexanamide	Investigative	135487604	C18H25N5O5	391.4	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C3=CNC(=O)NC3=O	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B2VC9Y	5-Chloro-N-{[(4s)-4-(1-Methyl-1h-Imidazol-2-Yl)-2,5-Dioxoimidazolidin-4-Yl]methyl}-1-Benzofuran-2-Carboxamide	Investigative	86287516	C17H14ClN5O4	387.8	CN1C=CN=C1[C@]2(C(=O)NC(=O)N2)CNC(=O)C3=CC4=C(O3)C=CC(=C4)Cl	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B3EUN1	[(3-Fluoroanilino)-phosphonomethyl]phosphonic acid	Investigative	72205111	C7H10FNO6P2	285.1	C1=CC(=CC(=C1)F)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B3TM2X	[(2,4-Dichloroanilino)-phosphono-methyl]phosphonic acid	Investigative	5276565	C7H9Cl2NO6P2	336	C1=CC(=C(C=C1Cl)Cl)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B3YB7F	N-Hydroxy-2-[4-(8-quinolylmethoxy)phenylsulfonylamino]acetamide	Investigative	72713868	C18H17N3O5S	387.4	C1=CC2=C(C(=C1)COC3=CC=C(C=C3)S(=O)(=O)NCC(=O)NO)N=CC=C2	IC50 = 120000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B4NH7Q	4-(4-Methylphenoxy)-N-(4-pyridinylmethyl)benzenecarboxamide	Investigative	4358655	C20H18N2O2	318.4	CC1=CC=C(C=C1)OC2=CC=C(C=C2)C(=O)NCC3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B52MUV	(5S)-4-[2-(1-Adamantyl)ethyl]-5-butyl-1-[(2S)-1-(4-hydroxyphenyl)-3-[(2S)-2-[[(6R)-6-(naphthalen-2-ylmethyl)-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]piperazine-2,3-dione	Investigative	122181996	C49H63N5O5	802.1	CCCC[C@H]1CN(C(=O)C(=O)N1CCC23CC4CC(C2)CC(C4)C3)[C@@H](CC5=CC=C(C=C5)O)CN6CCC[C@H]6CN7[C@@H](CNC(=O)C7=O)CC8=CC9=CC=CC=C9C=C8	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B5K0FT	3-{1-[(Methoxy-phenyl-methyl)-carbamoyl]-2,2-dimethyl-propylcarbamoyl}-6-(2-methyl-biphenyl-4-yl)-hexanoic acid	Investigative	44344631	C34H42N2O5	558.7	CC1=C(C=CC(=C1)CCC[C@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](C2=CC=CC=C2)OC)C(C)(C)C)C3=CC=CC=C3	IC50 = 66900 nM	Poor binder
T65019	Matrix metalloproteinase-14	B61DLV	[(4-Cyanoanilino)-phosphonomethyl]phosphonic acid	Investigative	72204932	C8H10N2O6P2	292.12	C1=CC(=CC=C1C#N)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B65WHM	4-[4-[2-[(3S)-3-Hydroxy-1-azabicyclo[2.2.2]octan-3-yl]ethynyl]phenoxy]-N-methylbenzamide	Investigative	57392969	C23H24N2O3	376.4	CNC(=O)C1=CC=C(C=C1)OC2=CC=C(C=C2)C#C[C@@]3(CN4CCC3CC4)O	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B68HAL	2-(Benzyl-hydroxycarbamoylmethyl-amino)-N-[2-(4-sulfamoyl-phenyl)-ethyl]-acetamide	Investigative	25178356	C19H24N4O5S	420.5	C1=CC=C(C=C1)CN(CC(=O)NCCC2=CC=C(C=C2)S(=O)(=O)N)CC(=O)NO	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B6HBX9	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(phenylsulfonyl)amino]carbonyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	9890632	C21H28N4O6S	464.5	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C(=O)NS(=O)(=O)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B6O4DQ	(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]acrylamide	Investigative	53374826	C10H8F3NO2	231.17	C1=CC(=CC=C1/C=C/C(=O)NO)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B7AQZ3	9-(3,5-Difluorophenyl)-6-(ethylamino)-2-purinecarbonitrile	Investigative	44143091	C14H10F2N6	300.27	CCNC1=C2C(=NC(=N1)C#N)N(C=N2)C3=CC(=CC(=C3)F)F	IC50 = 134896.29 nM	Poor binder
T65019	Matrix metalloproteinase-14	B7L6VX	Chembl4160618	Investigative	145956426	C11H13N3O7S	331.3	C1=CC(=CC=C1[N+](=O)[O-])S(=O)(=O)N[C@@H](CCC(=O)N)C(=O)O	IC50 = 76300 nM	Poor binder
T65019	Matrix metalloproteinase-14	B7QJE6	Schembl21751149	Investigative	78426757	C48H59N5O5	786	C1C[C@H](N(C1)C[C@H](CC2=CC=CC=C2)N3C[C@@H](N(C(=O)C3=O)CCC45CC6CC(C4)CC(C6)C5)CC7=CC=C(C=C7)O)CN8[C@H](CNC(=O)C8=O)CC9=CC=CC=C9	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B83XTH	(2R)-N-Hydroxy-2-[4-(3,5-dibromobenzyloxy)phenylsulfonylamino]-4-(benzyloxycarbonylamino)butyramide	Investigative	72714322	C25H25Br2N3O7S	671.4	C1=CC=C(C=C1)COC(=O)NCC[C@H](C(=O)NO)NS(=O)(=O)C2=CC=C(C=C2)OCC3=CC(=CC(=C3)Br)Br	IC50 = 104000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B87SHX	N-[[(4S)-4-(1-Methylimidazol-2-yl)-2,5-dioxoimidazolidin-4-yl]methyl]-5-(trifluoromethyl)-1-benzofuran-2-carboxamide	Investigative	101910871	C18H14F3N5O4	421.3	CN1C=CN=C1[C@]2(C(=O)NC(=O)N2)CNC(=O)C3=CC4=C(O3)C=CC(=C4)C(F)(F)F	IC50 = 86000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B8DY7G	(R)-2-(4-Fluoro-3,5-dimethylphenylamino)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	24871537	C21H27F2N3O2	391.5	CC1=CC(=CC(=C1F)C)N[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B8JE1T	3-(4-(2-Oxo-2H-chromen-3-yl)-2-thioxo-2,3-dihydro-1H-imidazol-1-yl)benzoic acid	Investigative	4085085	C19H12N2O4S	364.4	C1=CC=C2C(=C1)C=C(C(=O)O2)C3=CN(C(=S)N3)C4=CC=CC(=C4)C(=O)O	IC50 = 51000 nM	Poor binder
T65019	Matrix metalloproteinase-14	B8KJ7I	(S)-2-(4-Fluoro-3,5-dimethylbenzyl)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	24871655	C22H28F2N2O2	390.5	CC1=CC(=CC(=C1F)C)C[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BA8T1M	(2R)-2-(4-Fluoro-3,5-dimethylphenoxy)-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	70693710	C23H30F2N2O3	420.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@H](C(=O)NO)OC2=CC(=C(C(=C2)C)F)C	Ki ~ 50000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BB5SG2	(5S)-4-[2-(1-Adamantyl)ethyl]-5-[(4-hydroxyphenyl)methyl]-1-[(2R)-1-[(2S)-2-[[(6R)-6-[(4-hydroxyphenyl)methyl]-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-naphthalen-2-ylpropan-2-yl]piperazine-2,3-dione	Investigative	122181997	C52H61N5O6	852.1	C1C[C@H](N(C1)C[C@@H](CC2=CC3=CC=CC=C3C=C2)N4C[C@@H](N(C(=O)C4=O)CCC56CC7CC(C5)CC(C7)C6)CC8=CC=C(C=C8)O)CN9[C@@H](CNC(=O)C9=O)CC1=CC=C(C=C1)O	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BBM0L7	(3-Bromophenylamino)Methylenediphosphonic Acid	Investigative	5277481	C7H10BrNO6P2	346.01	C1=CC(=CC(=C1)Br)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BC2DS7	(5S)-5-[[4-[5-[(3-Ethyl-1,2-oxazol-5-yl)methoxy]pyrimidin-2-yl]piperazin-1-yl]sulfonylmethyl]-5-methylimidazolidine-2,4-dione	Investigative	73349097	C19H25N7O6S	479.5	CCC1=NOC(=C1)COC2=CN=C(N=C2)N3CCN(CC3)S(=O)(=O)C[C@@]4(C(=O)NC(=O)N4)C	IC50 = 98907 nM	Poor binder
T65019	Matrix metalloproteinase-14	BC6DG0	(2S)-2-[(4-Fluoro-3,5-dimethylphenyl)methyl]-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	57345501	C24H32F2N2O2	418.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@@H](CC2=CC(=C(C(=C2)C)F)C)C(=O)NO	Ki ~ 50000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BC6T0Q	(5S)-5-Benzyl-1-[(2R)-1-[(2S)-2-[[(6R)-6-benzyl-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-cyclohexylpropan-2-yl]-4-(2-phenylethyl)piperazine-2,3-dione	Investigative	122181999	C44H55N5O4	717.9	C1CCC(CC1)C[C@H](CN2CCC[C@H]2CN3[C@@H](CNC(=O)C3=O)CC4=CC=CC=C4)N5C[C@@H](N(C(=O)C5=O)CCC6=CC=CC=C6)CC7=CC=CC=C7	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BC74NY	2-[2-[(E)-(5-Oxo-2-sulfanylideneimidazolidin-4-ylidene)methyl]phenoxy]acetic acid	Investigative	703233	C12H10N2O4S	278.29	C1=CC=C(C(=C1)/C=C/2\\C(=O)NC(=S)N2)OCC(=O)O	IC50 = 55000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BCE62Z	(2Z,NE)-N-benzylidene-4-(3,4-dimethoxyphenyl)-2-(phenylimino)thiazol-3(2H)-amine	Investigative	6882342	C24H21N3O2S	415.5	COC1=C(C=C(C=C1)C2=CSC(=NC3=CC=CC=C3)N2/N=C/C4=CC=CC=C4)OC	IC50 = 150000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BE9WV7	N-Hydroxy-2-[[4-[(4-phenylphenyl)methoxy]phenyl]sulfonylamino]acetamide	Investigative	72713863	C21H20N2O5S	412.5	C1=CC=C(C=C1)C2=CC=C(C=C2)COC3=CC=C(C=C3)S(=O)(=O)NCC(=O)NO	IC50 = 72000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BF0D9I	[Anilino(phosphono)methyl]phosphonic acid	Investigative	450256	C7H11NO6P2	267.11	C1=CC=C(C=C1)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BF6ZI1	N-Hydroxy-2-[4-(4-methanesulfinyl-phenoxy)-benzenesulfonyl]-benzamide	Investigative	44479458	C20H17NO6S2	431.5	CS(=O)C1=CC=C(C=C1)OC2=CC=C(C=C2)S(=O)(=O)C3=CC=CC=C3C(=O)NO	IC50 = 120000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BFB0L4	5-Pyridin-3-yl-1H-indole-2-carboxylic acid ethyl ester	Investigative	56850271	C16H14N2O2	266.29	CCOC(=O)C1=CC2=C(N1)C=CC(=C2)C3=CN=CC=C3	IC50 = 51000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BFJ52V	(S)-2-{4'-[(5-Chloro-4-isopropoxy-3-methyl-benzofuran-2-carbonyl)-amino]-biphenyl-4-sulfonylamino}-3-methyl-butyric acid	Investigative	11330861	C30H31ClN2O7S	599.1	CC1=C(OC2=C1C(=C(C=C2)Cl)OC(C)C)C(=O)NC3=CC=C(C=C3)C4=CC=C(C=C4)S(=O)(=O)N[C@@H](C(C)C)C(=O)O	IC50 = 50000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BGM15D	(2R,3S)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxychroman-3-yl 3,4-dihydroxy-5-methoxybenzoate	Investigative	42623564	C23H20O10	456.4	COC1=CC(=CC(=C1O)O)C(=O)O[C@H]2CC3=C(C=C(C=C3O[C@@H]2C4=CC(=C(C=C4)O)O)O)O	IC50 = 52000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BGN3P0	2-(2-(4-Methoxyphenylsulfonyl)phenyl)acetic Acid	Investigative	44479700	C15H14O5S	306.3	COC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2CC(=O)O	IC50 = 77000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BH0Q9X	N-Hydroxy-2-[4-[3-bromo-5-(p-anisyl)benzyloxy]phenylsulfonylamino]acetamide	Investigative	72714085	C22H21BrN2O6S	521.4	COC1=CC=C(C=C1)C2=CC(=CC(=C2)COC3=CC=C(C=C3)S(=O)(=O)NCC(=O)NO)Br	IC50 = 170000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BH5V7X	[(4-Hydroxyanilino)-phosphonomethyl]phosphonic acid	Investigative	72204933	C7H11NO7P2	283.11	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)O	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BHL76P	(2R,3S)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxychroman-3-yl 3,5-dihydroxy-4-methoxybenzoate	Investigative	42623563	C23H20O10	456.4	COC1=C(C=C(C=C1O)C(=O)O[C@H]2CC3=C(C=C(C=C3O[C@@H]2C4=CC(=C(C=C4)O)O)O)O)O	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BIBX94	CID 78426619	Investigative	78426619	C44H55N5O5	733.9	C1CCC(CC1)C[C@H](CN2CCC[C@H]2CN3[C@H](CNC(=O)C3=O)CC4=CC=CC=C4)N5C[C@@H](N(C(=O)C5=O)CCC6=CC=CC=C6)CC7=CC=C(C=C7)O	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BIPC43	(2E)-3-(N-Hydroxycarbamoyl)-2-(3-phenylpropylidene)propionyl-L-tryptophan-N-methylamide	Investigative	44434566	C25H28N4O4	448.5	CNC(=O)[C@H](CC1=CNC2=CC=CC=C21)NC(=O)/C(=C/CCC3=CC=CC=C3)/CC(=O)NO	IC50 = 53100 nM	Poor binder
T65019	Matrix metalloproteinase-14	BJ1LV0	(5S)-5-Benzyl-1-[(2R)-1-cyclohexyl-3-[(2S)-2-[[(6S)-2,3-dioxo-6-propylpiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]-4-(2-phenylethyl)piperazine-2,3-dione	Investigative	122181998	C40H55N5O4	669.9	CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]2CCCN2C[C@@H](CC3CCCCC3)N4C[C@@H](N(C(=O)C4=O)CCC5=CC=CC=C5)CC6=CC=CC=C6	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BJ2YI8	Cruzain-IN-1	Investigative	44143088	C14H10F2N6	300.27	CCN1C=NC2=C(N=C(N=C21)C#N)NC3=CC(=CC(=C3)F)F	IC50 = 72443.6 nM	Poor binder
T65019	Matrix metalloproteinase-14	BJW37Y	N-Hydroxy-2-[4-(3,5-dibromobenzyloxy)phenylsulfonylamino]acetamide	Investigative	72714082	C15H14Br2N2O5S	494.2	C1=CC(=CC=C1OCC2=CC(=CC(=C2)Br)Br)S(=O)(=O)NCC(=O)NO	IC50 = 113000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BJZL58	4-Chloroanilinomethylenebisphosphonic acid	Investigative	15629940	C7H10ClNO6P2	301.56	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)Cl	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BK5X2A	[(4-Fluoro-3-nitroanilino)-phosphonomethyl]phosphonic acid	Investigative	72205112	C7H9FN2O8P2	330.1	C1=CC(=C(C=C1NC(P(=O)(O)O)P(=O)(O)O)[N+](=O)[O-])F	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BKPV14	N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylidenemethyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide	Investigative	44330147	C30H37N3O5S	551.7	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)S(=O)(=O)CC(C=C4CCN(CC4)CC(C)C)N(C=O)O	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BL1Z7E	N-Hydroxy-N''-[(S)-1-((S)-1-phenyl-ethylcarbamoyl)-ethyl]-oxalamide	Investigative	44384090	C13H17N3O4	279.29	C[C@@H](C1=CC=CC=C1)NC(=O)[C@H](C)NC(=O)C(=O)NO	Ki = 180000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BL58TM	Chembl4162521	Investigative	145957734	C15H21N3O7S	387.4	CCCCNC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)[N+](=O)[O-]	IC50 = 111350 nM	Poor binder
T65019	Matrix metalloproteinase-14	BN83ED	(5S)-5-[[4-[5-[(4-Fluorophenyl)methoxy]pyrimidin-2-yl]piperazin-1-yl]sulfonylmethyl]-5-methylimidazolidine-2,4-dione	Investigative	73346037	C20H23FN6O5S	478.5	C[C@]1(C(=O)NC(=O)N1)CS(=O)(=O)N2CCN(CC2)C3=NC=C(C=N3)OCC4=CC=C(C=C4)F	IC50 ~ 99999 nM	Poor binder
T65019	Matrix metalloproteinase-14	BO9WL8	(4s)-3-{[4-(4-Cyano-2-Methylphenyl)piperazin-1-Yl]sulfonyl}-N-Hydroxy-1,3-Thiazolidine-4-Carboxamide	Investigative	117094707	C16H21N5O4S2	411.5	CC1=C(C=CC(=C1)C#N)N2CCN(CC2)S(=O)(=O)N3CSC[C@@H]3C(=O)NO	IC50 = 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BOC1P3	[(3-Nitroanilino)-phosphono-methyl]phosphonic acid	Investigative	5277490	C7H10N2O8P2	312.11	C1=CC(=CC(=C1)[N+](=O)[O-])NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BQ07HA	(2s)-6-[(4-Fluorobenzyl)amino]-2-[(2r)-2-(4-Fluorophenyl)-2-Methoxyethyl]-N-Hydroxyhexanamide	Investigative	54582019	C22H28F2N2O3	406.5	CO[C@H](C[C@H](CCCCNCC1=CC=C(C=C1)F)C(=O)NO)C2=CC=C(C=C2)F	Ki ~ 50000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BR28PO	Chembl4163839	Investigative	145959777	C18H19N3O7S	421.4	C1=CC=C(C=C1)CNC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C2=CC=C(C=C2)[N+](=O)[O-]	IC50 = 109000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BR6BS8	N-[4-[[4-[2-(2,5-Dimethylpyridin-4-yl)ethyl]piperidin-1-yl]sulfonylmethyl]oxan-4-yl]-N-hydroxyformamide	Investigative	54580051	C21H33N3O5S	439.6	CC1=CC(=C(C=N1)C)CCC2CCN(CC2)S(=O)(=O)CC3(CCOCC3)N(C=O)O	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BT16SP	Benzyl 6-Benzyl-5,7-Dioxo-6,7-Dihydro-5h-[1,3]thiazolo[3,2-C]pyrimidine-2-Carboxylate	Investigative	9896504	C21H16N2O4S	392.4	C1=CC=C(C=C1)CN2C(=O)C=C3N(C2=O)C=C(S3)C(=O)OCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BTP5Y8	(2S)-2-[(2R)-2-(4-Fluorophenyl)-2-methoxyethyl]-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	57345502	C24H32F2N2O3	434.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@@H](C[C@H](C2=CC=C(C=C2)F)OC)C(=O)NO	Ki ~ 50000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BTWA58	(1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-3-(2-methoxy-phenylsulfanyl)-propyl]-phosphinic acid	Investigative	10462640	C38H41N4O7PS	728.8	COC1=CC=CC=C1SCC(CP(=O)(C(CC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3)O)C(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)N	Ki = 160000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BU72GZ	N-[(3S,4S)-1-(6-Aminohexanoyl)-4-hydroxypyrrolidin-3-yl]-4-phenoxybenzenesulfonamide;hydrochloride	Investigative	71680867	C22H30ClN3O5S	484	C1[C@@H]([C@H](CN1C(=O)CCCCCN)O)NS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3.Cl	Ki = 85000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BU86KW	[[4-(4-Chlorophenoxy)anilino]-phosphonomethyl]phosphonic acid	Investigative	72205114	C13H14ClNO7P2	393.65	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)OC2=CC=C(C=C2)Cl	IC50 = 76000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BUO20M	[Phosphono-[3-(trifluoromethyl)anilino]methyl]phosphonic acid	Investigative	72204934	C8H10F3NO6P2	335.11	C1=CC(=CC(=C1)NC(P(=O)(O)O)P(=O)(O)O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BW35RO	(2R)-2-(4-Fluoro-3,5-dimethylanilino)-6-[1-(4-fluorophenyl)propylamino]-N-hydroxyhexanamide	Investigative	57345500	C23H31F2N3O2	419.5	CCC(C1=CC=C(C=C1)F)NCCCC[C@H](C(=O)NO)NC2=CC(=C(C(=C2)C)F)C	Ki ~ 50000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BX28NQ	Chembl4164016	Investigative	145960035	C13H17N3O7S	359.36	CCNC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)[N+](=O)[O-]	IC50 = 87100 nM	Poor binder
T65019	Matrix metalloproteinase-14	BX78KQ	(R)-2-(4-Fluoro-3,5-dimethylphenoxy)-6-(4-fluorobenzylamino)-N-hydroxyhexanamide	Investigative	54580973	C21H26F2N2O3	392.4	CC1=CC(=CC(=C1F)C)O[C@H](CCCCNCC2=CC=C(C=C2)F)C(=O)NO	Ki ~ 50000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BXUI62	Benzyl N-[(4R)-4-[[4-[(3,5-dibromophenyl)methoxy]phenyl]sulfonylamino]-5-(hydroxyamino)-5-oxopentyl]carbamate	Investigative	72714323	C26H27Br2N3O7S	685.4	C1=CC=C(C=C1)COC(=O)NCCC[C@H](C(=O)NO)NS(=O)(=O)C2=CC=C(C=C2)OCC3=CC(=CC(=C3)Br)Br	IC50 = 68000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BY0QU5	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(methylsulfonyl)amino]-methyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	10271604	C16H28N4O5S	388.5	CS(=O)(=O)NCC1=NOC(=N1)[C@H](CCCC2CCCCC2)CC(=O)NO	Ki ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BZP8X7	[(4-Fluoroanilino)-phosphonomethyl]phosphonic acid	Investigative	72204928	C7H10FNO6P2	285.1	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)F	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	BZWU56	[(Naphthalen-1-ylamino)-phosphonomethyl]phosphonic acid	Investigative	19382975	C11H13NO6P2	317.17	C1=CC=C2C(=C1)C=CC=C2NC(P(=O)(O)O)P(=O)(O)O	IC50 = 69000 nM	Poor binder
T65019	Matrix metalloproteinase-14	D04GOO	N1,N3-bis(3-methoxybenzyl)isophthalamide	Investigative	10111838	C24H24N2O4	404.5	COC1=CC=CC(=C1)CNC(=O)C2=CC(=CC=C2)C(=O)NCC3=CC(=CC=C3)OC	IC50 ~ 100000 nM	Poor binder
T65019	Matrix metalloproteinase-14	D04PAW	Methotrexate gamma-L-phenylalaninehydroxamic acid	Investigative	16216218	C29H32N10O6	616.6	CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NO)C(=O)O	IC50 = 70000 nM	Poor binder
T65019	Matrix metalloproteinase-14	D06HSC	Folate gamma-L-phenylalaninehydroxamic acid	Investigative	136117931	C28H29N9O7	603.6	.	IC50 = 80000 nM	Poor binder