TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T65501	DNA [cytosine-5]-methyltransferase 3B	B0QMY9	(2R,3R,4S,5S)-2-(6-Amino-9H-purin-9-yl)-5-(((S)-pyrrolidin-2-ylmethylthio)methyl)tetrahydrofuran-3,4-diol	Investigative	45273096	C15H22N6O3S	366.4	C1C[C@H](NC1)CSC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O	IC50 = 100000 nM	Poor binder
T65501	DNA [cytosine-5]-methyltransferase 3B	BKBP72	(2S,4R)-4-(((2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylthio)pyrrolidine-2-carboxylic acid	Investigative	45271416	C15H20N6O5S	396.4	C1[C@H](CN[C@@H]1C(=O)O)SC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O	IC50 = 54000 nM	Poor binder
T65501	DNA [cytosine-5]-methyltransferase 3B	BQWD28	(2R,3R,4S,5S)-2-(6-Amino-9H-purin-9-yl)-5-((azetidin-3-ylthio)methyl)tetrahydrofuran-3,4-diol	Investigative	45271353	C13H18N6O3S	338.39	C1C(CN1)SC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O	IC50 ~ 100000 nM	Poor binder
T65501	DNA [cytosine-5]-methyltransferase 3B	BRA2N1	2-Amino-4-(((2S,3S,4R,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl)methylthio)butanoic acid	Investigative	45273086	C14H19ClN6O5S	418.9	C1=NC2=C(N=C(N=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CSCCC(C(=O)O)N)O)O)Cl)N	IC50 = 57200 nM	Poor binder
T65501	DNA [cytosine-5]-methyltransferase 3B	BVNU32	1-(2-((((2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)thio)ethyl)-3-ethylurea	Investigative	122178085	C15H23N7O4S	397.5	CCNC(=O)NCCSC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O	IC50 ~ 50000 nM	Poor binder
T65501	DNA [cytosine-5]-methyltransferase 3B	BZ1H9B	(2R,3R,4S,5S)-2-(6-Amino-9H-purin-9-yl)-5-(((1R,2S)-2-aminocyclopentylthio)methyl)tetrahydrofuran-3,4-diol	Investigative	45273097	C15H22N6O3S	366.4	C1C[C@@H]([C@@H](C1)SC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O)N	IC50 = 66000 nM	Poor binder
T65501	DNA [cytosine-5]-methyltransferase 3B	BZ2B0L	(2R,4S)-4-(((2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylthio)piperidine-2-carboxylic acid	Investigative	45272318	C16H22N6O5S	410.5	C1CN[C@H](C[C@H]1SC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder