TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T67272	Aminopeptidase N	D0U2JP	Sitagliptin	Approved	4369359	C16H15F6N5O	407.31	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N	IC50 ~ 100000 nM	Poor binder
T67272	Aminopeptidase N	B03NIX	(2S,4S)-Methyl 4-((E)-3-(3,4-dimethoxyphenyl)acrylamido)-1-acetylpyrrolidine-2-carboxylate	Investigative	25147058	C19H24N2O6	376.4	CC(=O)N1C[C@H](C[C@H]1C(=O)OC)NC(=O)/C=C/C2=CC(=C(C=C2)OC)OC	IC50 = 161800 nM	Poor binder
T67272	Aminopeptidase N	B05PIL	Chembl4174570	Investigative	73672383	C21H28ClFN4O6	486.9	CC(C)C[C@@H](C(=O)OCN1C=C(C(=O)NC1=O)F)NC(=O)[C@H]([C@@H](CC2=CC=CC=C2)N)O.Cl	IC50 = 65290 nM	Poor binder
T67272	Aminopeptidase N	B07AEJ	(2S,4S)-1-(3-(3,4-Dimethoxyphenyl)propanoyl)-4-(cinnamamido)-N-hydroxypyrrolidine-2-carboxamide	Investigative	25147252	C25H29N3O6	467.5	COC1=C(C=C(C=C1)CCC(=O)N2C[C@H](C[C@H]2C(=O)NO)NC(=O)/C=C/C3=CC=CC=C3)OC	IC50 = 96600 nM	Poor binder
T67272	Aminopeptidase N	B0EA3Z	(3S)-2-(Benzenesulfonyl)-N-hydroxy-6,11-dioxa-2-azaspiro[4.6]undecane-3-carboxamide	Investigative	44576635	C15H20N2O6S	356.4	C1CCOC2(C[C@H](N(C2)S(=O)(=O)C3=CC=CC=C3)C(=O)NO)OC1	IC50 = 106700 nM	Poor binder
T67272	Aminopeptidase N	B0LC8T	4-Benzoyloxy-1-methanesulfonyl-pyrrolidine-2-carboxylicacid methyl ester	Investigative	44569059	C14H17NO6S	327.35	COC(=O)[C@@H]1C[C@H](CN1S(=O)(=O)C)OC(=O)C2=CC=CC=C2	IC50 = 53600 nM	Poor binder
T67272	Aminopeptidase N	B15SNK	(2S)-5-(Diaminomethylideneamino)-2-[[(2R)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]pentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]pentanoic acid	Investigative	122195270	C29H48N12O8	692.8	C1=CC=C(C=C1)C[C@@H](C(=O)N[C@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)N	IC50 = 85000 nM	Poor binder
T67272	Aminopeptidase N	B17YAU	(2S,4S)-4-[[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]amino]-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]pyrrolidine-2-carboxylic acid	Investigative	53353383	C28H33F3N4O6	578.6	C[C@@H](C(=O)N1C[C@H](C[C@H]1C(=O)O)NC(=O)C[C@@H](CC2=CC(=C(C=C2F)F)F)N)N[C@@H](CCC3=CC=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67272	Aminopeptidase N	B1G4NY	2-(2-((3-(4-Hydroxybenzyl)-5-aminobenzamido)methyl)phenyl)acetic acid	Investigative	44560557	C23H22N2O4	390.4	C1=CC=C(C(=C1)CC(=O)O)CNC(=O)C2=CC(=CC(=C2)CC3=CC=C(C=C3)O)N	Ki ~ 100000 nM	Poor binder
T67272	Aminopeptidase N	B1K0ZC	(2S,5S,8Z,13S)-13-Amino-N-benzyl-2-[(4-hydroxyphenyl)methyl]-1-methyl-3,14-dioxo-1,4-diazacyclotetradec-8-ene-5-carboxamide	Investigative	53259405	C28H36N4O4	492.6	CN1[C@H](C(=O)N[C@@H](CC/C=C\\CCC[C@@H](C1=O)N)C(=O)NCC2=CC=CC=C2)CC3=CC=C(C=C3)O	Ki ~ 100000 nM	Poor binder
T67272	Aminopeptidase N	B1L6NO	(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(Diaminomethylideneamino)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]pentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]propanoic acid	Investigative	70696054	C26H41N9O8	607.7	C[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)N	IC50 ~ 70000 nM	Poor binder
T67272	Aminopeptidase N	B1P5BT	(2S)-N-Hydroxy-4-methylsulfanyl-2-(2-phenylethylcarbamoylamino)butanamide	Investigative	70696450	C14H21N3O3S	311.4	CSCC[C@@H](C(=O)NO)NC(=O)NCCC1=CC=CC=C1	IC50 = 110000 nM	Poor binder
T67272	Aminopeptidase N	B1PV5K	(2S,4S)-Methyl 1-acetyl-4-(benzamido)pyrrolidine-2-carboxylate	Investigative	11942810	C15H18N2O4	290.31	CC(=O)N1C[C@H](C[C@H]1C(=O)OC)NC(=O)C2=CC=CC=C2	IC50 = 122500 nM	Poor binder
T67272	Aminopeptidase N	B1YV5K	1-Tosyl-4-oxo-L-proline methyl ester	Investigative	44576563	C13H15NO5S	297.33	CC1=CC=C(C=C1)S(=O)(=O)N2CC(=O)C[C@H]2C(=O)OC	IC50 = 54900 nM	Poor binder
T67272	Aminopeptidase N	B20OKU	(S)-2-((1R,2S)-2-Amino-1-cyano-3-phenyl-propylamino)-3-phenyl-propionic acid methyl ester	Investigative	44283908	C20H23N3O2	337.4	COC(=O)[C@H](CC1=CC=CC=C1)N[C@@H](C#N)[C@H](CC2=CC=CC=C2)N	IC50 = 85000 nM	Poor binder
T67272	Aminopeptidase N	B20WPF	Methyl (2S,4R)-1-(4-methylphenyl)sulfonyl-4-(4-methylphenyl)sulfonyloxypyrrolidine-2-carboxylate	Investigative	391527	C20H23NO7S2	453.5	CC1=CC=C(C=C1)S(=O)(=O)N2C[C@@H](C[C@H]2C(=O)OC)OS(=O)(=O)C3=CC=C(C=C3)C	IC50 = 101400 nM	Poor binder
T67272	Aminopeptidase N	B2L8EF	(2S,5S,7Z,13S)-13-Amino-N-benzyl-2-[(4-hydroxyphenyl)methyl]-1-methyl-3,14-dioxo-1,4-diazacyclotetradec-7-ene-5-carboxamide	Investigative	53259403	C28H36N4O4	492.6	CN1[C@H](C(=O)N[C@@H](C/C=C\\CCCC[C@@H](C1=O)N)C(=O)NCC2=CC=CC=C2)CC3=CC=C(C=C3)O	Ki ~ 100000 nM	Poor binder
T67272	Aminopeptidase N	B2OI0M	(2S)-2-[[(2S)-2-[[2-[Benzyl-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]pentanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	Investigative	56953765	C29H48N12O8	692.8	C1=CC=C(C=C1)CN(CC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)N	IC50 ~ 100000 nM	Poor binder
T67272	Aminopeptidase N	B31HXL	(S)-2-((1S,2S)-2-Amino-1-cyano-3-phenyl-propylamino)-3-phenyl-propionic acid methyl ester	Investigative	44283924	C20H23N3O2	337.4	COC(=O)[C@H](CC1=CC=CC=C1)N[C@H](C#N)[C@H](CC2=CC=CC=C2)N	IC50 = 146000 nM	Poor binder
T67272	Aminopeptidase N	B3V1QS	1-Methanesulfonyl-4-(3-phenyl-acryloyloxy)-pyrrolidine-2-carboxylic acid methyl ester	Investigative	44569081	C16H19NO6S	353.4	COC(=O)[C@@H]1C[C@H](CN1S(=O)(=O)C)OC(=O)/C=C/C2=CC=CC=C2	IC50 = 114300 nM	Poor binder
T67272	Aminopeptidase N	B40XSC	(2S,4S)-Methyl 1-acetyl-4-(pyrazine-2-carboxamido)-pyrrolidine-2-carboxylate	Investigative	25147248	C13H16N4O4	292.29	CC(=O)N1C[C@H](C[C@H]1C(=O)OC)NC(=O)C2=NC=CN=C2	IC50 = 82600 nM	Poor binder
T67272	Aminopeptidase N	B41BNM	(3R)-3-Amino-1-(2-benzoyldiazepan-1-yl)-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	16739330	C22H25ClF3N3O2	455.9	C1CCN(N(CC1)C(=O)C2=CC=CC=C2)C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.Cl	IC50 ~ 100000 nM	Poor binder
T67272	Aminopeptidase N	B43FLX	(2S)-5-(Diaminomethylideneamino)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]pentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]pentanoic acid	Investigative	70681503	C30H50N12O8	706.8	C[C@H]([C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)N)O	IC50 ~ 100000 nM	Poor binder
T67272	Aminopeptidase N	B4BYV0	(S)-2-((S)-1-((S)-2-((4R,7S,10R)-10-Amino-7-(4-hydroxybenzyl)-6,9-dioxo-1,2-dithia-5,8-diazacycloundecane-4-carboxamido)-3-(1H-imidazol-5-yl)propanoyl)pyrrolidine-2-carboxamido)-3-phenylpropanoic acid	Investigative	52941108	C35H42N8O8S2	766.9	C1C[C@H](N(C1)C(=O)[C@H](CC2=CN=CN2)NC(=O)[C@@H]3CSSC[C@@H](C(=O)N[C@H](C(=O)N3)CC4=CC=C(C=C4)O)N)C(=O)N[C@@H](CC5=CC=CC=C5)C(=O)O	Ki = 57000 nM	Poor binder
T67272	Aminopeptidase N	B4DQ1Y	(S)-7-(Toluene-4-sulfonyl)-1,4-dioxa-7-aza-spiro[4.4]nonane-8-carboxylic acid methyl ester	Investigative	44576587	C15H19NO6S	341.4	CC1=CC=C(C=C1)S(=O)(=O)N2CC3(C[C@H]2C(=O)OC)OCCO3	IC50 = 155800 nM	Poor binder
T67272	Aminopeptidase N	B4GV3K	(2S)-5-(Carbamoylamino)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]pentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]pentanoic acid	Investigative	122195275	C29H47N11O9	693.8	C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=O)N)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)N	IC50 = 62000 nM	Poor binder
T67272	Aminopeptidase N	B57KRT	4-Hydroxy-2-(2-methylsulfanyl-phenyl)-isoindole-1,3-dione	Investigative	44368725	C15H11NO3S	285.3	CSC1=CC=CC=C1N2C(=O)C3=C(C2=O)C(=CC=C3)O	IC50 = 133900 nM	Poor binder
T67272	Aminopeptidase N	B58LGR	(2S,4S)-4-[[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]amino]-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]butanoyl]pyrrolidine-2-carboxylic acid	Investigative	53354470	C29H35F3N4O6	592.6	CC[C@@H](C(=O)N1C[C@H](C[C@H]1C(=O)O)NC(=O)C[C@@H](CC2=CC(=C(C=C2F)F)F)N)N[C@@H](CCC3=CC=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67272	Aminopeptidase N	B5OUV9	(2S,4S)-Methyl 1-acetyl-4-azidopyrrolidine-2-carboxylate	Investigative	44563970	C8H12N4O3	212.21	CC(=O)N1C[C@H](C[C@H]1C(=O)OC)N=[N+]=[N-]	IC50 = 73700 nM	Poor binder
T67272	Aminopeptidase N	B5X3BL	Ethyl 2-[(3S)-3-[[(2S)-2-aminopropanoyl]amino]-2,6-dioxopiperidin-1-yl]acetate;hydrochloride	Investigative	44481389	C12H20ClN3O5	321.76	CCOC(=O)CN1C(=O)CC[C@@H](C1=O)NC(=O)[C@H](C)N.Cl	IC50 = 64300 nM	Poor binder
T67272	Aminopeptidase N	B6EBP3	(1-Amino-3-methylbutyl)phosphonic acid	Investigative	182612	C5H14NO3P	167.14	CC(C)CC(N)P(=O)(O)O	Ki = 53000 nM	Poor binder
T67272	Aminopeptidase N	B6G9CK	4-Amino-2-(2,6-dimethylphenyl)isoindole-1,3-dione	Investigative	10333136	C16H14N2O2	266.29	CC1=C(C(=CC=C1)C)N2C(=O)C3=C(C2=O)C(=CC=C3)N	IC50 = 108900 nM	Poor binder
T67272	Aminopeptidase N	B6LTQ1	(2S,4S)-Methyl 1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-4-(nicotinamido)pyrrolidine-2-carboxylate	Investigative	25147249	C23H25N3O6	439.5	COC1=C(C=C(C=C1)/C=C/C(=O)N2C[C@H](C[C@H]2C(=O)OC)NC(=O)C3=CN=CC=C3)OC	IC50 = 137300 nM	Poor binder
T67272	Aminopeptidase N	B6VF3S	2-(5'-Fluoro-2'-oxospiro[1,3-dioxane-2,3'-indole]-1'-yl)-N-hydroxyacetamide	Investigative	71603244	C13H13FN2O5	296.25	C1COC2(C3=C(C=CC(=C3)F)N(C2=O)CC(=O)NO)OC1	IC50 = 97490 nM	Poor binder
T67272	Aminopeptidase N	B7J9TQ	1-Methanesulfonyl-4-(toluene-4-sulfonyloxy)-pyrrolidine-2-carboxylic acid methyl ester	Investigative	44569061	C14H19NO7S2	377.4	CC1=CC=C(C=C1)S(=O)(=O)O[C@@H]2C[C@H](N(C2)S(=O)(=O)C)C(=O)OC	IC50 = 68900 nM	Poor binder
T67272	Aminopeptidase N	B7NT1J	4-(4-Chloro-benzoyloxy)-1-(toluene-4-sulfonyl)-pyrrolidine-2-carboxylic acid methyl ester	Investigative	44569011	C20H20ClNO6S	437.9	CC1=CC=C(C=C1)S(=O)(=O)N2C[C@@H](C[C@H]2C(=O)OC)OC(=O)C3=CC=C(C=C3)Cl	IC50 = 51200 nM	Poor binder
T67272	Aminopeptidase N	B7PGD9	1-Benzenesulfonyl-4-(toluene-4-sulfonyloxy)-pyrrolidine-2-carboxylic acid methyl ester	Investigative	44569038	C19H21NO7S2	439.5	CC1=CC=C(C=C1)S(=O)(=O)O[C@@H]2C[C@H](N(C2)S(=O)(=O)C3=CC=CC=C3)C(=O)OC	IC50 = 61300 nM	Poor binder
T67272	Aminopeptidase N	B7VJ4S	trans-1-Benzenesulfonyl-4-hydroxy-pyrrolidine-2-carboxylic acid methyl ester	Investigative	18445902	C12H15NO5S	285.32	COC(=O)[C@@H]1C[C@H](CN1S(=O)(=O)C2=CC=CC=C2)O	IC50 = 53800 nM	Poor binder
T67272	Aminopeptidase N	B81BUO	(2S)-5-(Diaminomethylideneamino)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]pentanoyl]amino]-4-phenylbutanoyl]amino]-3-hydroxypropanoyl]amino]pentanoic acid	Investigative	56953762	C30H50N12O8	706.8	C1=CC=C(C=C1)CC[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)N	IC50 = 54000 nM	Poor binder
T67272	Aminopeptidase N	B8SZH3	(2S,4S)-Methyl 4-amino-1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)pyrrolidine-2-carboxylate	Investigative	25147157	C17H22N2O5	334.4	COC1=C(C=C(C=C1)/C=C/C(=O)N2C[C@H](C[C@H]2C(=O)OC)N)OC	IC50 = 70600 nM	Poor binder
T67272	Aminopeptidase N	B9AE7Y	(2S,4S)-4-[[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]amino]-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid	Investigative	53354369	C31H39F3N4O6	620.7	CCCC[C@@H](C(=O)N1C[C@H](C[C@H]1C(=O)O)NC(=O)C[C@@H](CC2=CC(=C(C=C2F)F)F)N)N[C@@H](CCC3=CC=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67272	Aminopeptidase N	B9CLD4	Methyl (8S)-7-(benzenesulfonyl)-1,4-dioxa-7-azaspiro[4.4]nonane-8-carboxylate	Investigative	44576616	C14H17NO6S	327.35	COC(=O)[C@@H]1CC2(CN1S(=O)(=O)C3=CC=CC=C3)OCCO2	IC50 = 150600 nM	Poor binder
T67272	Aminopeptidase N	B9FDB3	(S)-2-(Toluene-4-sulfonyl)-6,10-dioxa-2-aza-spiro[4.5]decane-3-carboxylic acid methyl ester	Investigative	44576614	C16H21NO6S	355.4	CC1=CC=C(C=C1)S(=O)(=O)N2CC3(C[C@H]2C(=O)OC)OCCCO3	IC50 = 173700 nM	Poor binder
T67272	Aminopeptidase N	B9I0JE	Methyl (3S)-2-(4-methylphenyl)sulfonyl-6,11-dioxa-2-azaspiro[4.6]undecane-3-carboxylate	Investigative	44576615	C17H23NO6S	369.4	CC1=CC=C(C=C1)S(=O)(=O)N2CC3(C[C@H]2C(=O)OC)OCCCCO3	IC50 = 124300 nM	Poor binder
T67272	Aminopeptidase N	B9M1YW	(3S)-N-Hydroxy-2-(4-methylphenyl)sulfonyl-6,10-dioxa-2-azaspiro[4.5]decane-3-carboxamide	Investigative	44576631	C15H20N2O6S	356.4	CC1=CC=C(C=C1)S(=O)(=O)N2CC3(C[C@H]2C(=O)NO)OCCCO3	IC50 = 61800 nM	Poor binder
T67272	Aminopeptidase N	B9TE2I	(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-Amino-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-5-oxopentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	Investigative	70683617	C38H57N13O9	839.9	C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)N	IC50 = 122000 nM	Poor binder
T67272	Aminopeptidase N	BB81XH	(2S,4S)-Methyl 1-(3-(3,4-dimethoxyphenyl)propanoyl)-4-aminopyrrolidine-2-carboxylate	Investigative	25146959	C17H24N2O5	336.4	COC1=C(C=C(C=C1)CCC(=O)N2C[C@H](C[C@H]2C(=O)OC)N)OC	IC50 = 68400 nM	Poor binder
T67272	Aminopeptidase N	BC47SI	1-Benzenesulfonyl-4-oxo-pyrrolidine-2-carboxylicacid methyl ester	Investigative	44576564	C12H13NO5S	283.3	COC(=O)[C@@H]1CC(=O)CN1S(=O)(=O)C2=CC=CC=C2	IC50 = 75800 nM	Poor binder
T67272	Aminopeptidase N	BCG82T	(2S,4S)-Methyl 4-(4-bromobenzamido)-1-acetylpyrrolidine-2-carboxylate	Investigative	25146960	C15H17BrN2O4	369.21	CC(=O)N1C[C@H](C[C@H]1C(=O)OC)NC(=O)C2=CC=C(C=C2)Br	IC50 = 149300 nM	Poor binder
T67272	Aminopeptidase N	BCV1L8	(2S)-5-(Diaminomethylideneamino)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]pentanoyl]amino]-3-(2,3,4,5,6-pentafluorophenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]pentanoic acid	Investigative	56953636	C29H43F5N12O8	782.7	C(C[C@@H](C(=O)N[C@@H](CC1=C(C(=C(C(=C1F)F)F)F)F)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CCC(=O)N)N)CN=C(N)N	IC50 ~ 100000 nM	Poor binder
T67272	Aminopeptidase N	BD0O8Q	Methyl 2-((2S,4S)-4-(3,4,5-trimethoxybenzamido)-1-acetylpyrrolidine-2-carboxamido)acetate	Investigative	25147155	C20H27N3O8	437.4	CC(=O)N1C[C@H](C[C@H]1C(=O)NCC(=O)OC)NC(=O)C2=CC(=C(C(=C2)OC)OC)OC	IC50 = 121500 nM	Poor binder
T67272	Aminopeptidase N	BDE8J2	2-(2-(((5R,8S,11R)-11-Amino-8-(4-hydroxybenzyl)-7,10-dioxo-1,2-dithia-6,9-diazacyclotridecane-5-carboxamido)methyl)phenyl)acetic acid	Investigative	52946764	C26H32N4O6S2	560.7	C1CSSCC[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]1N)CC2=CC=C(C=C2)O)C(=O)NCC3=CC=CC=C3CC(=O)O	Ki = 50000 nM	Poor binder
T67272	Aminopeptidase N	BDU26Q	1-Benzenesulfonyl-4-(3-phenyl-acryloyloxy)-pyrrolidine-2-carboxylic acid methyl ester	Investigative	44569058	C21H21NO6S	415.5	COC(=O)[C@@H]1C[C@H](CN1S(=O)(=O)C2=CC=CC=C2)OC(=O)/C=C/C3=CC=CC=C3	IC50 = 134700 nM	Poor binder
T67272	Aminopeptidase N	BE39PL	2-(2,6-Diisopropylphenyl)-4,5,6,7-tetrafluoroisoindoline-1,3-dithione	Investigative	44368736	C20H17F4NS2	411.5	CC(C)C1=C(C(=CC=C1)C(C)C)N2C(=S)C3=C(C2=S)C(=C(C(=C3F)F)F)F	IC50 = 98400 nM	Poor binder
T67272	Aminopeptidase N	BE71VH	(2S,4S)-Methyl 1-acetyl-4-(nicotinamido)pyrrolidine-2-carboxylate	Investigative	25147352	C14H17N3O4	291.3	CC(=O)N1C[C@H](C[C@H]1C(=O)OC)NC(=O)C2=CN=CC=C2	IC50 = 78400 nM	Poor binder
T67272	Aminopeptidase N	BF89TS	(2S,5S,8E,13S)-13-Amino-N-benzyl-2-[(4-hydroxyphenyl)methyl]-1-methyl-3,14-dioxo-1,4-diazacyclotetradec-8-ene-5-carboxamide	Investigative	53259404	C28H36N4O4	492.6	CN1[C@H](C(=O)N[C@@H](CC/C=C/CCC[C@@H](C1=O)N)C(=O)NCC2=CC=CC=C2)CC3=CC=C(C=C3)O	Ki ~ 100000 nM	Poor binder
T67272	Aminopeptidase N	BFPQ19	(2S,3R)-2-(3-(4-Hydroxybenzyl)-5-((S)-2-amino-3-methylbutanamido)benzamido)-3-methylpentanoic acid	Investigative	44560558	C25H33N3O5	455.5	CC[C@@H](C)[C@@H](C(=O)O)NC(=O)C1=CC(=CC(=C1)CC2=CC=C(C=C2)O)NC(=O)[C@H](C(C)C)N	Ki = 69000 nM	Poor binder
T67272	Aminopeptidase N	BG8AX4	(2R)-2-[4-[[[(2S)-3-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-1,3-thiazolidine-2-carbonyl]amino]methyl]anilino]-3-methylbutanoic acid;hydrochloride	Investigative	24860299	C26H32ClF3N4O4S	589.1	CC(C)[C@H](C(=O)O)NC1=CC=C(C=C1)CNC(=O)[C@H]2N(CCS2)C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.Cl	IC50 ~ 100000 nM	Poor binder
T67272	Aminopeptidase N	BH01MZ	(2S)-6-Amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]pentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]hexanoic acid	Investigative	122195273	C29H48N10O8	664.8	C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)N	IC50 ~ 70000 nM	Poor binder
T67272	Aminopeptidase N	BH50KZ	(3R)-3-Amino-1-(2-benzoyldiazinan-1-yl)-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride	Investigative	23628283	C21H23ClF3N3O2	441.9	C1CCN(N(C1)C(=O)C[C@@H](CC2=CC(=C(C=C2F)F)F)N)C(=O)C3=CC=CC=C3.Cl	IC50 ~ 100000 nM	Poor binder
T67272	Aminopeptidase N	BHN72Z	Phe-Ser-Arg	Investigative	44207184	C18H28N6O5	408.5	C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)N	IC50 = 120000 nM	Poor binder
T67272	Aminopeptidase N	BI4E5U	1-Amino-2-methylbutylphosphonic acid monophenylester	Investigative	46886333	C11H18NO3P	243.24	CC(C)CC(N)P(=O)(O)OC1=CC=CC=C1	Ki = 53000 nM	Poor binder
T67272	Aminopeptidase N	BIA8G9	(2-Diphenoxyphosphorylpyrrolidin-1-yl)-[(2R)-pyrrolidin-2-yl]methanone;hydrochloride	Investigative	49795928	C21H26ClN2O4P	436.9	C1C[C@@H](NC1)C(=O)N2CCCC2P(=O)(OC3=CC=CC=C3)OC4=CC=CC=C4.Cl	IC50 = 83000 nM	Poor binder
T67272	Aminopeptidase N	BJ05MU	(2R)-N-[(2S,3S)-2-Amino-3-hydroxy-3-(4-nitrophenyl)propyl]-2-[[(2S)-3-amino-2-hydroxypropanoyl]amino]-3-phenylpropanamide	Investigative	56665197	C21H27N5O6	445.5	C1=CC=C(C=C1)C[C@H](C(=O)NC[C@@H]([C@H](C2=CC=C(C=C2)[N+](=O)[O-])O)N)NC(=O)[C@H](CN)O	IC50 = 66340 nM	Poor binder
T67272	Aminopeptidase N	BJ60FT	(2S,4S)-4-(3,4,5-Trimethoxybenzamido)-1-acetylpyrrolidine-2-carboxylic acid	Investigative	25147154	C17H22N2O7	366.4	CC(=O)N1C[C@H](C[C@H]1C(=O)O)NC(=O)C2=CC(=C(C(=C2)OC)OC)OC	IC50 = 51400 nM	Poor binder
T67272	Aminopeptidase N	BJFK14	(2S)-1-[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide	Investigative	16121107	C17H24N4O4	348.4	C[C@@H](C(=O)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC2=CC=C(C=C2)O)N	Ki = 80000 nM	Poor binder
T67272	Aminopeptidase N	BJU7N1	Tyr-Pro-Ala	Investigative	16121199	C17H23N3O5	349.4	C[C@@H](C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC2=CC=C(C=C2)O)N	Ki = 100000 nM	Poor binder
T67272	Aminopeptidase N	BL9NF6	Ethyl 2-[[4-[[4-[(2-ethoxy-2-oxoethyl)carbamoyl]phenoxy]-[1-(pyrrolidine-2-carbonyl)pyrrolidin-2-yl]phosphoryl]oxybenzoyl]amino]acetate;hydrochloride	Investigative	49795932	C31H40ClN4O10P	695.1	CCOC(=O)CNC(=O)C1=CC=C(C=C1)OP(=O)(C2CCCN2C(=O)C3CCCN3)OC4=CC=C(C=C4)C(=O)NCC(=O)OCC.Cl	IC50 = 104000 nM	Poor binder
T67272	Aminopeptidase N	BLG5D0	(2S)-2-[[(2S)-3-[(2R,3R,4R,5S,6R)-3-Acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]pentanoyl]amino]-3-phenylpropanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	Investigative	122195277	C37H61N13O13	896	CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1OC[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)N)CO)O)O	IC50 = 52000 nM	Poor binder
T67272	Aminopeptidase N	BLM71O	(2S)-5-(Diaminomethylideneamino)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]pentanoyl]amino]-3-(3-fluorophenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]pentanoic acid	Investigative	56955271	C29H47FN12O8	710.8	C1=CC(=CC(=C1)F)C[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)N	IC50 ~ 100000 nM	Poor binder
T67272	Aminopeptidase N	BLW9G8	(2S,4S)-4-[[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]amino]-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]pentanoyl]pyrrolidine-2-carboxylic acid	Investigative	53354365	C30H37F3N4O6	606.6	CCC[C@@H](C(=O)N1C[C@H](C[C@H]1C(=O)O)NC(=O)C[C@@H](CC2=CC(=C(C=C2F)F)F)N)N[C@@H](CCC3=CC=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T67272	Aminopeptidase N	BM5X3H	(2S,4S)-Methyl 1-(3-(3,4-dimethoxyphenyl)propanoyl)-4-(nicotinamido)pyrrolidine-2-carboxylate	Investigative	25147059	C23H27N3O6	441.5	COC1=C(C=C(C=C1)CCC(=O)N2C[C@H](C[C@H]2C(=O)OC)NC(=O)C3=CN=CC=C3)OC	IC50 = 196400 nM	Poor binder
T67272	Aminopeptidase N	BM6KR8	Methyl (3S)-2-(benzenesulfonyl)-6,10-dioxa-2-azaspiro[4.5]decane-3-carboxylate	Investigative	44576617	C15H19NO6S	341.4	COC(=O)[C@@H]1CC2(CN1S(=O)(=O)C3=CC=CC=C3)OCCCO2	IC50 = 168100 nM	Poor binder
T67272	Aminopeptidase N	BNH3E5	(3S)-N-Hydroxy-2-(4-methylphenyl)sulfonyl-6,11-dioxa-2-azaspiro[4.6]undecane-3-carboxamide	Investigative	44576632	C16H22N2O6S	370.4	CC1=CC=C(C=C1)S(=O)(=O)N2CC3(C[C@H]2C(=O)NO)OCCCCO3	IC50 = 73200 nM	Poor binder
T67272	Aminopeptidase N	BNT2I6	(2S)-5-(Diaminomethylideneamino)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]pentanoic acid	Investigative	70685541	C26H41N9O8	607.7	C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CCC(=O)N)N	IC50 = 65000 nM	Poor binder
T67272	Aminopeptidase N	BO6LN7	(2S,4S)-1-Acetyl-4-(cinnamamido)-N-hydroxypyrrolidine-2-carboxamide	Investigative	25147251	C16H19N3O4	317.34	CC(=O)N1C[C@H](C[C@H]1C(=O)NO)NC(=O)/C=C/C2=CC=CC=C2	IC50 = 56100 nM	Poor binder
T67272	Aminopeptidase N	BO8PW0	2-(2-(((2S,3R)-2-(3-(4-Hydroxybenzyl)-5-aminobenzamido)-3-methylpentanamido)methyl)phenyl)acetic acid	Investigative	44560412	C29H33N3O5	503.6	CC[C@@H](C)[C@@H](C(=O)NCC1=CC=CC=C1CC(=O)O)NC(=O)C2=CC(=CC(=C2)CC3=CC=C(C=C3)O)N	Ki ~ 100000 nM	Poor binder
T67272	Aminopeptidase N	BOF17Z	(2S)-5-(Diaminomethylideneamino)-2-[[(2S)-2-[[(3R)-3-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]pentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]pentanoic acid	Investigative	56953638	C29H48N12O8	692.8	C1=CC=C(C=C1)[C@@H](CC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)N	IC50 ~ 70000 nM	Poor binder
T67272	Aminopeptidase N	BON0V4	4-Amino-N-(2,6-dimethylphenyl)phthalimide	Investigative	124031	C16H14N2O2	266.29	CC1=C(C(=CC=C1)C)N2C(=O)C3=C(C2=O)C=C(C=C3)N	IC50 = 56300 nM	Poor binder
T67272	Aminopeptidase N	BPR04C	(2S,4S)-Methyl 1-acetyl-4-(cinnamamido)pyrrolidine-2-carboxylate	Investigative	25147057	C17H20N2O4	316.35	CC(=O)N1C[C@H](C[C@H]1C(=O)OC)NC(=O)/C=C/C2=CC=CC=C2	IC50 = 135300 nM	Poor binder
T67272	Aminopeptidase N	BQA72O	5-Amino-2-benzyl-7-methyl-4-oxo-octanoic acid	Investigative	14542149	C16H23NO3	277.36	CC(C)C[C@@H](C(=O)CC(CC1=CC=CC=C1)C(=O)O)N	Ki = 79000 nM	Poor binder
T67272	Aminopeptidase N	BQMC36	(2S,4S)-Methyl 4-(4-nitrobenzamido)-1-acetylpyrrolidine-2-carboxylate	Investigative	25147159	C15H17N3O6	335.31	CC(=O)N1C[C@H](C[C@H]1C(=O)OC)NC(=O)C2=CC=C(C=C2)[N+](=O)[O-]	IC50 = 72300 nM	Poor binder
T67272	Aminopeptidase N	BQS5F1	(2S)-5-(Diaminomethylideneamino)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]pentanoic acid	Investigative	70692015	C29H48N12O9	708.8	C1=CC(=CC=C1C[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)N)O	IC50 = 64000 nM	Poor binder
T67272	Aminopeptidase N	BR1U3M	(6R,7S)-7-Amino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-6-ol;hydrochloride	Investigative	53324938	C11H16ClNO	213.7	C1CC2=CC=CC=C2C[C@H]([C@H]1N)O.Cl	Ki = 60000 nM	Poor binder
T67272	Aminopeptidase N	BRS2J5	2-(((S)-1-(3-(4-Hydroxybenzyl)-5-((S)-2-amino-3-methylbutanamido)benzoyl)pyrrolidine-2-carboxamido)methyl)benzoic acid	Investigative	44560402	C32H36N4O6	572.7	CC(C)[C@@H](C(=O)NC1=CC(=CC(=C1)C(=O)N2CCC[C@H]2C(=O)NCC3=CC=CC=C3C(=O)O)CC4=CC=C(C=C4)O)N	Ki = 55000 nM	Poor binder
T67272	Aminopeptidase N	BRTJ30	Opiorphin (1-4)	Investigative	70683616	C23H36N8O7	536.6	C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CO)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)N	IC50 = 75000 nM	Poor binder
T67272	Aminopeptidase N	BSNW56	(2S,4R)-Methyl 4-hydroxy-1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)pyrrolidine-2-carboxylate	Investigative	25146956	C17H21NO6	335.4	COC1=C(C=C(C=C1)/C=C/C(=O)N2C[C@@H](C[C@H]2C(=O)OC)O)OC	IC50 = 81800 nM	Poor binder
T67272	Aminopeptidase N	BT3Z8O	4-Benzenesulfonyloxy-1-(toluene-4-sulfonyl)-pyrrolidine-2-carboxylic acid methyl ester	Investigative	44569012	C19H21NO7S2	439.5	CC1=CC=C(C=C1)S(=O)(=O)N2C[C@@H](C[C@H]2C(=O)OC)OS(=O)(=O)C3=CC=CC=C3	IC50 = 74600 nM	Poor binder
T67272	Aminopeptidase N	BTA9Y6	(2S)-5-(Diaminomethylideneamino)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,4-diamino-4-oxobutanoyl]amino]pentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]pentanoic acid	Investigative	70696244	C28H46N12O8	678.7	C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(=O)N)N	IC50 ~ 100000 nM	Poor binder
T67272	Aminopeptidase N	BTE6Q8	(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-Amino-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]hexanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	Investigative	122195272	C29H48N10O8	664.8	C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)N)N	IC50 ~ 70000 nM	Poor binder
T67272	Aminopeptidase N	BTWI21	(3S)-2-(Benzenesulfonyl)-N-hydroxy-6,10-dioxa-2-azaspiro[4.5]decane-3-carboxamide	Investigative	44576634	C14H18N2O6S	342.37	C1COC2(C[C@H](N(C2)S(=O)(=O)C3=CC=CC=C3)C(=O)NO)OC1	IC50 = 82700 nM	Poor binder
T67272	Aminopeptidase N	BU6BI1	(2S,4S)-Methyl 1-acetyl-4-(isonicotinamido)pyrrolidine-2-carboxylate	Investigative	25147056	C14H17N3O4	291.3	CC(=O)N1C[C@H](C[C@H]1C(=O)OC)NC(=O)C2=CC=NC=C2	IC50 = 74800 nM	Poor binder
T67272	Aminopeptidase N	BUB5S9	(2S)-5-(Diaminomethylideneamino)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]pentanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]pentanoic acid	Investigative	70681348	C23H44N12O8	616.7	C[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)N	IC50 ~ 70000 nM	Poor binder
T67272	Aminopeptidase N	BUH7R1	N-((3S,5S)-5-(Hydroxycarbamoyl)-1-(3-(3,4-dimethoxyphenyl)propanoyl)pyrrolidin-3-yl)nicotinamide	Investigative	25147062	C22H26N4O6	442.5	COC1=C(C=C(C=C1)CCC(=O)N2C[C@H](C[C@H]2C(=O)NO)NC(=O)C3=CN=CC=C3)OC	IC50 = 62200 nM	Poor binder
T67272	Aminopeptidase N	BUP34N	(2S,5S,7E,13S)-13-Amino-N-benzyl-2-[(4-hydroxyphenyl)methyl]-1-methyl-3,14-dioxo-1,4-diazacyclotetradec-7-ene-5-carboxamide	Investigative	53259219	C28H36N4O4	492.6	CN1[C@H](C(=O)N[C@@H](C/C=C/CCCC[C@@H](C1=O)N)C(=O)NCC2=CC=CC=C2)CC3=CC=C(C=C3)O	Ki ~ 100000 nM	Poor binder
T67272	Aminopeptidase N	BUR2O0	(2S)-2-[[(2S)-2-[[(2S)-3-(2-Bromophenyl)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]pentanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	Investigative	56955173	C29H47BrN12O8	771.7	C1=CC=C(C(=C1)C[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)N)Br	IC50 = 65000 nM	Poor binder
T67272	Aminopeptidase N	BV5K3Q	(2S,4S)-Methyl 4-azido-1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)pyrrolidine-2-carboxylate	Investigative	25146957	C17H20N4O5	360.4	COC1=C(C=C(C=C1)/C=C/C(=O)N2C[C@H](C[C@H]2C(=O)OC)N=[N+]=[N-])OC	IC50 = 71300 nM	Poor binder
T67272	Aminopeptidase N	BVUR94	4-(3-Phenyl-acryloyloxy)-1-(toluene-4-sulfonyl)-pyrrolidine-2-carboxylic acid methyl ester	Investigative	44569024	C22H23NO6S	429.5	CC1=CC=C(C=C1)S(=O)(=O)N2C[C@@H](C[C@H]2C(=O)OC)OC(=O)/C=C/C3=CC=CC=C3	IC50 = 168600 nM	Poor binder
T67272	Aminopeptidase N	BW8AJ7	(2S,4S)-Methyl 4-(4-chlorobenzamido)-1-acetylpyrrolidine-2-carboxylate	Investigative	25147158	C15H17ClN2O4	324.76	CC(=O)N1C[C@H](C[C@H]1C(=O)OC)NC(=O)C2=CC=C(C=C2)Cl	IC50 = 121700 nM	Poor binder
T67272	Aminopeptidase N	BWQ3U8	(2S)-2-[[(2S,3R)-3-[(2S,3R,4R,5S,6R)-3-Acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]pentanoyl]amino]-3-phenylpropanoyl]amino]butanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid	Investigative	122195278	C38H63N13O13	910	C[C@H]([C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)NC(=O)C	IC50 ~ 100000 nM	Poor binder
T67272	Aminopeptidase N	BXG5J0	Ubenimex	Investigative	72172	C16H24N2O4	308.37	CC(C)C[C@@H](C(=O)O)NC(=O)[C@H]([C@@H](CC1=CC=CC=C1)N)O	IC50 = 54700 nM	Poor binder
T67272	Aminopeptidase N	BXN49S	CID 44593458	Investigative	44593458	C22H24N4O6	440.4	COC1=C(C=C(C=C1)/C=C/C(=O)N2C[C@H](C[C@H]2C(=O)NO)NC(=O)C3=CN=CC=C3)OC	IC50 = 141900 nM	Poor binder
T67272	Aminopeptidase N	BXWS05	1-Methanesulfonyl-4-oxo-pyrrolidine-2-carboxylicacid methyl ester	Investigative	44576565	C7H11NO5S	221.23	COC(=O)[C@@H]1CC(=O)CN1S(=O)(=O)C	IC50 = 92600 nM	Poor binder
T67272	Aminopeptidase N	BY2RA7	3-Amino-N-hydroxy-4-phenyl-butyramide	Investigative	44276218	C10H14N2O2	194.23	C1=CC=C(C=C1)CC(CC(=O)NO)N	IC50 = 75000 nM	Poor binder
T67272	Aminopeptidase N	BY9E4T	Methyl (3S)-2-(benzenesulfonyl)-6,11-dioxa-2-azaspiro[4.6]undecane-3-carboxylate	Investigative	44576618	C16H21NO6S	355.4	COC(=O)[C@@H]1CC2(CN1S(=O)(=O)C3=CC=CC=C3)OCCCCO2	IC50 = 134800 nM	Poor binder
T67272	Aminopeptidase N	BZ85EK	(2S,4S)-Methyl 4-(3,4,5-trimethoxybenzamido)-1-acetylpyrrolidine-2-carboxylate	Investigative	25147153	C18H24N2O7	380.4	CC(=O)N1C[C@H](C[C@H]1C(=O)OC)NC(=O)C2=CC(=C(C(=C2)OC)OC)OC	IC50 = 98400 nM	Poor binder
T67272	Aminopeptidase N	BZH68M	(8S)-7-(Benzenesulfonyl)-N-hydroxy-1,4-dioxa-7-azaspiro[4.4]nonane-8-carboxamide	Investigative	44576633	C13H16N2O6S	328.34	C1COC2(O1)C[C@H](N(C2)S(=O)(=O)C3=CC=CC=C3)C(=O)NO	IC50 = 57800 nM	Poor binder
T67272	Aminopeptidase N	D0I6RL	2-(phenylsulfonamido)-1-naphthoic acid	Investigative	11723962	C17H13NO4S	327.4	C1=CC=C(C=C1)S(=O)(=O)NC2=C(C3=CC=CC=C3C=C2)C(=O)O	IC50 ~ 100000 nM	Poor binder