TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T67619	RAC-alpha serine/threonine-protein kinase	D0J9ZR	Niclosamide	Approved	4477	C13H8Cl2N2O4	327.12	C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O	IC50 = 59400 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	D0M9QZ	ABT-869	Phase 3	11485656	C21H18FN5O	375.4	CC1=CC(=C(C=C1)F)NC(=O)NC2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N	IC50 = 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	D0L4FS	Genistein	Phase 2	5280961	C15H10O5	270.24	C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O	IC50 ~ 70000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B05JUW	Tert-butyl N-[benzyl-(2-chloroacetyl)amino]carbamate	Investigative	90645490	C14H19ClN2O3	298.76	CC(C)(C)OC(=O)NN(CC1=CC=CC=C1)C(=O)CCl	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B0AWX2	Phenylaminoethyl guanidine deriv., 21be	Investigative	44590356	C36H34F2N6O	604.7	C1=CC=C(C=C1)C2=C(C=CC(=C2)C(=O)NC3=CC=C(C=C3)N(CC4=CC=C(C=C4)F)CC5=CC=C(C=C5)F)NCCN=C(N)N	IC50 = 55000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B0HX8M	3-Methyl-4-(2-phenoxyacetamido)-1H-thieno[2,3-c]pyrazole-5-carboxamide	Investigative	44406048	C15H14N4O3S	330.4	CC1=C2C(=C(SC2=NN1)C(=O)N)NC(=O)COC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B0JRA3	Phenylaminoethyl guanidine deriv., 21ba	Investigative	44590352	C36H36N6O	568.7	C1=CC=C(C=C1)CN(CC2=CC=CC=C2)C3=CC=C(C=C3)NC(=O)C4=CC(=C(C=C4)NCCN=C(N)N)C5=CC=CC=C5	IC50 = 84000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B0M4XA	4-Phenyl-1H-pyrazole	Investigative	139106	C9H8N2	144.17	C1=CC=C(C=C1)C2=CNN=C2	IC50 = 135000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B0N6VA	6-Phenyl-8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepine-4-amine	Investigative	10705154	C13H13N5	239.28	C1CNC2=NC=NC(=C2N=C1C3=CC=CC=C3)N	IC50 = 92000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B0WLH8	N-(7-Methoxyquinolin-6-yl)thieno[3,2-d]pyrimidine-7-carboxamide	Investigative	58056356	C17H12N4O2S	336.4	COC1=C(C=C2C=CC=NC2=C1)NC(=O)C3=CSC4=CN=CN=C43	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B0WV4G	p38 MAP Kinase Inhibitor IX	Investigative	16730109	C22H17N7O2	411.4	CC1=C(C=C(C=C1)C(=O)NC2=NOC=C2)NC3=C4C=NN(C4=NC=N3)C5=CC=CC=C5	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B16YOQ	Phenylaminoethyl guanidine deriv., 21bd	Investigative	44590355	C48H44N6O	720.9	C1=CC=C(C=C1)C2=CC=C(C=C2)CN(CC3=CC=C(C=C3)C4=CC=CC=C4)C5=CC=C(C=C5)NC(=O)C6=CC(=C(C=C6)NCCN=C(N)N)C7=CC=CC=C7	IC50 = 84000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B1A4EI	(8S,16S)-3,16-Dihydroxy-9,10-seco-1,3,5(10)-cholestatrien-9-one	Investigative	9547398	C27H42O3	414.6	CC1=C(C=C(C=C1)O)CC[C@H]2[C@@H]3C[C@@H]([C@@H]([C@]3(CCC2=O)C)[C@H](C)CCCC(C)C)O	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B1EZW6	N12C3=CC=CC=C3N(C)C3=CC=CC=C3C2=NN=C1C1=CC=C(C=CC=C2)C2=C1	Investigative	58458633	C25H18N4	374.4	CN1C2=CC=CC=C2C3=NN=C(N3C4=CC=CC=C41)C5=CC6=CC=CC=C6C=C5	IC50 = 67000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B1VO9R	Calicoferol E	Investigative	5283685	C27H42O2	398.6	CC1=C(C=C(C=C1)O)CC[C@H]2[C@@H]3CC[C@@H]([C@]3(CCC2=O)C)[C@H](C)CCCC(C)C	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B2EX3Y	4-(1-Methylbenzimidazol-2-yl)-N-(4-methylphenyl)pyrimidin-2-amine	Investigative	60165994	C19H17N5	315.4	CC1=CC=C(C=C1)NC2=NC=CC(=N2)C3=NC4=CC=CC=C4N3C	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B2MDN9	Chembl4168160	Investigative	145956191	C18H17N5O5S2	447.5	C1CCC2=C(C1)C=CC(=C2)OCC3=NN=C(O3)SCC(=O)NC4=NC=C(S4)[N+](=O)[O-]	IC50 = 138330 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B2MVL4	Phenylaminoethyl guanidine deriv., 21aa	Investigative	44590351	C30H32N6O	492.6	C1=CC=C(C=C1)CN(CC2=CC=CC=C2)C3=CC=C(C=C3)NC(=O)C4=CC=C(C=C4)NCCN=C(N)N	IC50 = 96000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B2REH1	4-[2-(4-Methylphenyl)-5-(piperidin-4-ylmethoxy)pyridin-3-yl]benzenecarbonitrile	Investigative	127027348	C25H25N3O	383.5	CC1=CC=C(C=C1)C2=C(C=C(C=N2)OCC3CCNCC3)C4=CC=C(C=C4)C#N	IC50 = 87600 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B2VJY5	6-Phenyl-7,8-dihydro-9H-pyrimido[4,5-b][1,4]diazepine-2,4-diamine	Investigative	10538870	C13H14N6	254.29	C1CNC2=NC(=NC(=C2N=C1C3=CC=CC=C3)N)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B2VZ7Y	N-((S)-1-((S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-ylamino)-3-methyl-1-oxobutan-2-yl)-4-(2-guanidinoethyl)benzamide	Investigative	44440160	C31H38N6O3	542.7	CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC2=CC=CC=C2)NC(=O)C3=CC=C(C=C3)CCN=C(N)N	IC50 = 120000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B31SIO	6-(3-Methylphenyl)-8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepin-4-amine	Investigative	44450059	C14H15N5	253.3	CC1=CC(=CC=C1)C2=NC3=C(N=CN=C3NCC2)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B3E4AB	N-(4-{[(1S)-1-{[(1S)-1-(Benzylcarbamoyl)-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}phenyl)-5-carbamimidamidopentanamide	Investigative	44440153	C34H43N7O4	613.7	CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC2=CC=CC=C2)NC(=O)C3=CC=C(C=C3)NC(=O)CCCCN=C(N)N	IC50 = 193000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B3JOK1	6-Chloro-5-[(3,5-dimethylphenyl)sulfanyl]-1H-indazole-4,7-dione	Investigative	44420171	C15H11ClN2O2S	318.8	CC1=CC(=CC(=C1)SC2=C(C(=O)C3=C(C2=O)C=NN3)Cl)C	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B3LYC9	4-(1-Methylbenzimidazol-2-yl)-N-(4-morpholin-4-ylphenyl)pyrimidin-2-amine	Investigative	60166135	C22H22N6O	386.4	CN1C2=CC=CC=C2N=C1C3=NC(=NC=C3)NC4=CC=C(C=C4)N5CCOCC5	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B3RAE6	3-(5-Chloro-2-{[1-(dimethylamino)propan-2-yl]oxy}phenyl)-1-(5-cyanopyrazin-2-yl)urea	Investigative	11417488	C17H19ClN6O2	374.8	CC(CN(C)C)OC1=C(C=C(C=C1)Cl)NC(=O)NC2=NC=C(N=C2)C#N	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B3T9QN	Methyl 4-(6-(4-(methoxycarbonylamino)phenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate	Investigative	44219749	C24H29N7O5	495.5	COC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=NN3C4CCN(CC4)C(=O)OC)C(=N2)N5CCOCC5	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B3X1LZ	N-(2-Methoxyethyl)-5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine	Investigative	46232269	C8H9N5O3S3	319.4	COCCNC1=NN=C(S1)SC2=NC=C(S2)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B4D7QC	5-(Pyridin-3-ylmethylamino)quinazoline-8-carboxamide	Investigative	89647504	C15H13N5O	279.3	C1=CC(=CN=C1)CNC2=C3C=NC=NC3=C(C=C2)C(=O)N	IC50 = 70000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B4HU5D	Cyclapolin 9	Investigative	2779952	C9H4F3N3O4S	307.21	C1=C(C=C(C2=C1[N+](=C(S2)C(=O)N)[O-])[N+](=O)[O-])C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B4P9TV	N-(3,4-Dimethoxyphenethyl)-5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine	Investigative	46232270	C15H15N5O4S3	425.5	COC1=C(C=C(C=C1)CCNC2=NN=C(S2)SC3=NC=C(S3)[N+](=O)[O-])OC	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B4YXC8	7-[[(1R,2S,4Ar,8aS)-1,2,4a,5-tetramethyl-2,3,4,7,8,8a-hexahydronaphthalen-1-yl]methyl]-5-methoxy-2-methyl-1,3-benzoxazol-6-ol	Investigative	76335685	C24H33NO3	383.5	C[C@H]1CC[C@@]2([C@H]([C@]1(C)CC3=C4C(=CC(=C3O)OC)N=C(O4)C)CCC=C2C)C	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B57VLC	N-[4-(1,3,4-Thiadiazol-2-ylsulfamoyl)phenyl]acetamide	Investigative	694845	C10H10N4O3S2	298.3	CC(=O)NC1=CC=C(C=C1)S(=O)(=O)NC2=NN=CS2	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B5PAJ3	C1CC(N)Ccn1C(=O)C1=CC=C(C=2N3C4=CC=CN=C4NC4=CC=CC=C4C3=NN=2)C=C1	Investigative	136163832	C25H23N7O	437.5	C1CN(CCC1N)C(=O)C2=CC=C(C=C2)C3=NN=C4N3C5=C(NC6=CC=CC=C64)N=CC=C5	IC50 = 70000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B5SQ2I	1-{1-[(4-{5-[(4-Hydroxyphenyl)methyl]-6-oxo-3-phenyl-1,6-dihydropyrazin-2-yl}phenyl)methyl]piperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one	Investigative	23647019	C36H33N5O3	583.7	C1CN(CCC1N2C3=CC=CC=C3NC2=O)CC4=CC=C(C=C4)C5=C(N=C(C(=O)N5)CC6=CC=C(C=C6)O)C7=CC=CC=C7	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B5VKU3	5-[4-(3,4-Difluorophenyl)piperazin-1-yl]quinazoline-8-carboxamide	Investigative	89651660	C19H17F2N5O	369.4	C1CN(CCN1C2=CC(=C(C=C2)F)F)C3=C4C=NC=NC4=C(C=C3)C(=O)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B5YNV2	6,6-Dimethyl-8-(1-(oxetan-3-yl)piperidin-4-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile	Investigative	53357328	C27H27N3O2	425.5	CC1(C2=C(C=CC(=C2)C3CCN(CC3)C4COC4)C(=O)C5=C1NC6=C5C=CC(=C6)C#N)C	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B60CAW	(R)-3-(6-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)quinolin-3-yl)acrylamide	Investigative	46232555	C20H15Cl2FN2O2	405.2	C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=CC3=CC(=CN=C3C=C2)/C=C/C(=O)N	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B63LRM	Artocarpesin	Investigative	399491	C20H18O6	354.4	CC(=CCC1=C(C2=C(C=C1O)OC(=CC2=O)C3=C(C=C(C=C3)O)O)O)C	IC50 = 54480 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B6A8ZF	Tert-butyl N-[(2S)-1-(2-chloroethylamino)-1-oxo-3-phenylpropan-2-yl]carbamate	Investigative	90645488	C16H23ClN2O3	326.82	CC(C)(C)OC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCCCl	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B6DN5P	N-(4-(N-1,3,4-Thiadiazol-2-ylsulfamoyl)phenyl)-2-(2-(2-methoxyethoxy)ethoxy)acetamide	Investigative	46226697	C15H20N4O6S2	416.5	COCCOCCOCC(=O)NC1=CC=C(C=C1)S(=O)(=O)NC2=NN=CS2	Ki ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B6E7VX	Tert-butyl N-[(2S)-3-oxo-1-phenylpentan-2-yl]carbamate	Investigative	12118709	C16H23NO3	277.36	CCC(=O)[C@H](CC1=CC=CC=C1)NC(=O)OC(C)(C)C	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B6I8YT	5-[3-(Aminomethyl)piperidin-1-yl]quinazoline-8-carboxamide	Investigative	89660494	C15H19N5O	285.34	C1CC(CN(C1)C2=C3C=NC=NC3=C(C=C2)C(=O)N)CN	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B6JF9I	5-[[4-[(4-Aminophenyl)sulfonylamino]phenyl]sulfonylamino]-1,3,4-thiadiazole-2-sulfonamide	Investigative	66656726	C14H14N6O6S4	490.6	C1=CC(=CC=C1N)S(=O)(=O)NC2=CC=C(C=C2)S(=O)(=O)NC3=NN=C(S3)S(=O)(=O)N	IC50 = 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B6NR3O	5-[4-(3-Chlorophenyl)piperazin-1-yl]quinazoline-8-carboxamide	Investigative	89651286	C19H18ClN5O	367.8	C1CN(CCN1C2=CC(=CC=C2)Cl)C3=C4C=NC=NC4=C(C=C3)C(=O)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B6TY8C	5-[3-Fluoro-4-[[6-methoxy-7-(3-morpholinopropoxy)quinolin-4-yl]oxy]phenyl]-2-(4-fluorophenylamino)-3-methylpyrimidin-4(3H)-one	Investigative	11858109	C34H33F2N5O5	629.7	CN1C(=O)C(=CN=C1NC2=CC=C(C=C2)F)C3=CC(=C(C=C3)OC4=C5C=C(C(=CC5=NC=C4)OCCCN6CCOCC6)OC)F	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B6WES9	5-[4-(5-Chloro-2-methylphenyl)piperazin-1-yl]quinazoline-8-carboxamide	Investigative	89651540	C20H20ClN5O	381.9	CC1=C(C=C(C=C1)Cl)N2CCN(CC2)C3=C4C=NC=NC4=C(C=C3)C(=O)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B70EJW	5-[2-Phenylethyl-[(3R)-piperidin-3-yl]amino]quinazoline-8-carboxamide	Investigative	117642362	C22H25N5O	375.5	C1C[C@H](CNC1)N(CCC2=CC=CC=C2)C3=C4C=NC=NC4=C(C=C3)C(=O)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B70GZQ	(2S)-N-[(1S)-1-(Benzylcarbamoyl)-2-phenylethyl]-2-({4-[(2S)-2-{[(2S)-1-[(2S)-5-carbamimidamido-2-(2-acetamidoacetamido)pentanoyl]pyrrolidin-2-yl]formamido}propanamido]phenyl}formamido)-3-methylbutanamide	Investigative	44440133	C46H61N11O8	896	C[C@@H](C(=O)NC1=CC=C(C=C1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)NCC3=CC=CC=C3)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)C	IC50 = 79000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B7GVJ1	5-(5-Nitrothiazol-2-ylthio)-N-propyl-1,3,4-thiadiazol-2-amine	Investigative	46232267	C8H9N5O2S3	303.4	CCCNC1=NN=C(S1)SC2=NC=C(S2)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B7IM6P	Tert-butyl N-[(2S)-1-(2-iodoethylamino)-1-oxo-3-phenylpropan-2-yl]carbamate	Investigative	14332591	C16H23IN2O3	418.27	CC(C)(C)OC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCCI	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B7TJ1A	4-[5-[(E)-(2-Amino-3,7-dicyano-4,6-dimethylcyclopenta[b]pyridin-5-ylidene)methyl]furan-2-yl]benzoic acid	Investigative	1207540	C24H16N4O3	408.4	CC\\1=C(C2=C(/C1=C/C3=CC=C(O3)C4=CC=C(C=C4)C(=O)O)C(=C(C(=N2)N)C#N)C)C#N	IC50 = 126000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B7ZDB8	(R)-6-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)quinoline	Investigative	46232443	C17H12Cl2FNO	336.2	C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=CC3=C(C=C2)N=CC=C3	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B83AMN	N-((S)-1-((S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-ylamino)-3-methyl-1-oxobutan-2-yl)-4-guanidinobenzamide	Investigative	44440155	C29H34N6O3	514.6	CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC2=CC=CC=C2)NC(=O)C3=CC=C(C=C3)N=C(N)N	IC50 = 77000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B8A4HK	6-Chloro-5-(4-fluoroanilino)-1H-indazole-4,7-dione	Investigative	44420157	C13H7ClFN3O2	291.66	C1=CC(=CC=C1NC2=C(C(=O)C3=C(C2=O)C=NN3)Cl)F	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B8CH3A	Indole-aryl scaffold, 36a	Investigative	44590405	C31H30N6O	502.6	C1=CC=C(C=C1)CN(CC2=CC=CC=C2)C3=CC4=C(C=C3)NC(=C4)C5=CC=C(C=C5)NC(=O)CN=C(N)N	IC50 = 126000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B8SG3L	5-[(2-Phenyl-2-piperazin-1-ylethyl)amino]quinazoline-8-carboxamide	Investigative	89648060	C21H24N6O	376.5	C1CN(CCN1)C(CNC2=C3C=NC=NC3=C(C=C2)C(=O)N)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B8YTQ3	CID 49806721	Investigative	49806721	C28H30N4O2	454.6	CCC1=CC2=C(C=C1N3CCN(CC3)C4COC4)C(C5=C(C2=O)C6=C(N5)C=C(C=C6)C#N)(C)C	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B91GEH	4-Hexyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide	Investigative	53322375	C14H19N3O2S2	325.5	CCCCCCC1=CC=C(C=C1)S(=O)(=O)NC2=NN=CS2	Ki ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B92EIU	N-[(S)-1-((S)-1-Benzylcarbamoyl-2-phenyl-ethylcarbamoyl)-2-methyl-propyl]-4-[(tert-butylcarbamoyl-methyl)-(5-guanidino-pentanoyl)-amino]-benzamide	Investigative	44440184	C40H54N8O5	726.9	CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC2=CC=CC=C2)NC(=O)C3=CC=C(C=C3)N(CC(=O)NC(C)(C)C)C(=O)CCCCN=C(N)N	IC50 = 58000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B92TXA	4-Amino-n-(1,3,4-thiadiazol-2-yl)benzenesulfonamide	Investigative	234762	C8H8N4O2S2	256.3	C1=CC(=CC=C1N)S(=O)(=O)NC2=NN=CS2	Ki ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B9HA2R	(2S)-5-Carbamimidamido-2-acetamido-N-(4-{[(1S)-2-methyl-1-{[(1S)-1-{[2-(naphthalen-2-yl)ethyl]carbamoyl}-2-phenylethyl]carbamoyl}propyl]carbamoyl}phenyl)pentanamide	Investigative	44440142	C41H50N8O5	734.9	CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCCC2=CC3=CC=CC=C3C=C2)NC(=O)C4=CC=C(C=C4)NC(=O)[C@H](CCCN=C(N)N)NC(=O)C	IC50 = 51000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B9KPT1	(2S)-5-Carbamimidamido-2-acetamido-N-(4-{[(1S)-2-methyl-1-{[(1S)-1-{[2-(naphthalen-1-yl)ethyl]carbamoyl}-2-phenylethyl]carbamoyl}propyl]carbamoyl}phenyl)pentanamide	Investigative	44440145	C41H50N8O5	734.9	CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCCC2=CC=CC3=CC=CC=C32)NC(=O)C4=CC=C(C=C4)NC(=O)[C@H](CCCN=C(N)N)NC(=O)C	IC50 = 89000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	B9OES1	1-(3-(8-(Pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea	Investigative	11755812	C26H20F3N7O	503.5	C1=CC(=CC(=C1)NC(=O)NC2=CC=CC(=C2)C(F)(F)F)C3=CN4C=CN=C4C(=N3)NCC5=CC=NC=C5	IC50 = 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BA81HV	3-[[4-(1-Methylbenzimidazol-2-yl)pyrimidin-2-yl]amino]phenol	Investigative	60166139	C18H15N5O	317.3	CN1C2=CC=CC=C2N=C1C3=NC(=NC=C3)NC4=CC(=CC=C4)O	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BA84DU	Phenylaminoethyl guanidine deriv., 22ba	Investigative	44590363	C38H38N6O3	626.7	COC(=O)C1=CC=C(C=C1)C2=C(C=CC(=C2)C(=O)NC3=CC=C(C=C3)N(CC4=CC=CC=C4)CC5=CC=CC=C5)NCCN=C(N)N	IC50 = 158000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BB3T2M	1-Phenyl-4-methoxy-2-butene-1-one	Investigative	14044888	C11H12O2	176.21	COC/C=C/C(=O)C1=CC=CC=C1	IC50 = 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BB7Y3E	4-Butyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide	Investigative	53323734	C12H15N3O2S2	297.4	CCCCC1=CC=C(C=C1)S(=O)(=O)NC2=NN=CS2	Ki ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BC3K0L	Methyl 3-(piperidin-1-yl)-1H-thieno[2,3-c]pyrazole-5-carboxylate	Investigative	44405987	C13H17N3O2S	279.36	COC(=O)C1=CC2=C(NN=C2S1)CN3CCCCC3	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BCG3J8	2,3,6,8-Tetrahydroxy-1-methylxanthone	Investigative	10423452	C14H10O6	274.22	CC1=C(C(=CC2=C1C(=O)C3=C(C=C(C=C3O2)O)O)O)O	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BCKX05	5-[4-(3-Chloro-4-fluorophenyl)piperazin-1-yl]quinazoline-8-carboxamide	Investigative	89651732	C19H17ClFN5O	385.8	C1CN(CCN1C2=CC(=C(C=C2)F)Cl)C3=C4C=NC=NC4=C(C=C3)C(=O)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BCO6E2	5-[4-(3,4-Dichlorophenyl)piperazin-1-yl]quinazoline-8-carboxamide	Investigative	89650940	C19H17Cl2N5O	402.3	C1CN(CCN1C2=CC(=C(C=C2)Cl)Cl)C3=C4C=NC=NC4=C(C=C3)C(=O)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BCZ38X	(2S)-N-(4-{[(1S)-1-{[(1S)-1-(Benzylcarbamoyl)-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}phenyl)-5-carbamimidamido-2-acetamidopentanamide	Investigative	44440150	C36H46N8O5	670.8	CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC2=CC=CC=C2)NC(=O)C3=CC=C(C=C3)NC(=O)[C@H](CCCN=C(N)N)NC(=O)C	IC50 = 119000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BCZ67E	(2S)-N-(4-{[(1S)-1-{[(1S)-1-{[2-(4-Benzylpiperidin-1-yl)ethyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}phenyl)-5-carbamimidamido-2-{[(2S)-1-[(2S)-5-carbamimidamido-2-(2-acetamidoacetamido)pentanoyl]pyrrolidin-2-yl]formamido}pentanamide	Investigative	44440117	C56H81N15O8	1092.3	CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCCN2CCC(CC2)CC3=CC=CC=C3)NC(=O)C4=CC=C(C=C4)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]5CCCN5C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)C	IC50 = 94000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BDK42C	Desmethylxanthohumol	Investigative	6443339	C20H20O5	340.4	CC(=CCC1=C(C(=C(C=C1O)O)C(=O)/C=C/C2=CC=C(C=C2)O)O)C	IC50 = 143900 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BDK9R0	Calicoferol C	Investigative	10024683	C28H44O2	412.6	CC1=C(C=C(C=C1)O)CC[C@H]2[C@@H]3CC[C@@H]([C@]3(CC[C@H]2O)C)[C@H](C)CCC(=C)C(C)C	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BDU30B	5-[[(3R)-Pyrrolidin-3-yl]methylamino]quinazoline-8-carboxamide	Investigative	89647924	C14H17N5O	271.32	C1CNC[C@@H]1CNC2=C3C=NC=NC3=C(C=C2)C(=O)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BDW1H7	Tert-butyl N-[(2S)-1-(2-bromoethylamino)-1-oxo-3-phenylpropan-2-yl]carbamate	Investigative	15929390	C16H23BrN2O3	371.27	CC(C)(C)OC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCCBr	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BDXT45	3-(1H-Indol-3-yl)-4-(3,4,5-trimethoxyphenyl)pyrrole-2,5-dione	Investigative	11530963	C21H18N2O5	378.4	COC1=CC(=CC(=C1OC)OC)C2=C(C(=O)NC2=O)C3=CNC4=CC=CC=C43	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BEO65U	6-(3-Chlorophenyl)-8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepin-4-amine	Investigative	44450035	C13H12ClN5	273.72	C1CNC2=NC=NC(=C2N=C1C3=CC(=CC=C3)Cl)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BF0W8I	N-Sec-Butyl-5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine	Investigative	46232312	C9H11N5O2S3	317.4	CCC(C)NC1=NN=C(S1)SC2=NC=C(S2)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BF32AR	Calicoferol B	Investigative	10047545	C27H44O3	416.6	CC1=C(C=C(C=C1)O)CC[C@@H]2[C@@H](CC[C@]3([C@H]2C[C@@H]([C@@H]3[C@H](C)CCCC(C)C)O)C)O	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BG37WO	Astrogorgiadiol B	Investigative	5283727	C27H44O2	400.6	CC1=C(C=C(C=C1)O)CC[C@H]2[C@@H]3CC[C@@H]([C@]3(CC[C@H]2O)C)[C@H](C)CCCC(C)C	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BG5YC8	5-(Benzylamino)quinazoline-8-carboxamide	Investigative	89647758	C16H14N4O	278.31	C1=CC=C(C=C1)CNC2=C3C=NC=NC3=C(C=C2)C(=O)N	IC50 = 57000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BG63FT	6-(4-Chlorophenyl)-8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepine-4-amine	Investigative	10588346	C13H12ClN5	273.72	C1CNC2=NC=NC(=C2N=C1C3=CC=C(C=C3)Cl)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BGN8E6	(2S)-5-Carbamimidamido-2-{[(2S)-1-[(2S)-5-carbamimidamido-2-(2-acetamidoacetamido)pentanoyl]pyrrolidin-2-yl]formamido}-N-(4-{[(1S)-2-methyl-1-{[(1S)-1-{[2-(naphthalen-1-yl)ethyl]carbamoyl}-2-phenylethyl]carbamoyl}propyl]carbamoyl}phenyl)pentanamide	Investigative	44440111	C54H72N14O8	1045.2	CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCCC2=CC=CC3=CC=CC=C32)NC(=O)C4=CC=C(C=C4)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]5CCCN5C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)C	IC50 = 62000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BGQ73K	(E)-1-[2,4-Dihydroxy-5-(3-methylbut-2-enyl)phenyl]-3-(3-hydroxyphenyl)prop-2-en-1-one	Investigative	44205558	C20H20O4	324.4	CC(=CCC1=CC(=C(C=C1O)O)C(=O)/C=C/C2=CC(=CC=C2)O)C	IC50 = 85900 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BHR09P	N-{4-[(2,6-Dimethoxypyrimidin-4-yl)sulfamoyl]phenyl}furan-2-carboxamide	Investigative	1241577	C17H16N4O6S	404.4	COC1=NC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)NC(=O)C3=CC=CO3)OC	IC50 = 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BHV6I3	4-(1-Methylbenzimidazol-2-yl)-N-phenylpyrimidin-2-amine	Investigative	60165993	C18H15N5	301.3	CN1C2=CC=CC=C2N=C1C3=NC(=NC=C3)NC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BI3C9W	4-(2-Chlorobenzamido)-3-methyl-1H-thieno[2,3-c]pyrazole-5-carboxamide	Investigative	44405999	C14H11ClN4O2S	334.8	CC1=C2C(=C(SC2=NN1)C(=O)N)NC(=O)C3=CC=CC=C3Cl	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BJ4W8Y	5-(8-Quinolylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide	Investigative	394907	C11H9N5O4S3	371.4	C1=CC2=C(C(=C1)S(=O)(=O)NC3=NN=C(S3)S(=O)(=O)N)N=CC=C2	IC50 = 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BJQH85	5-[4-[4-(Trifluoromethyl)phenyl]piperazin-1-yl]quinazoline-8-carboxamide	Investigative	89651668	C20H18F3N5O	401.4	C1CN(CCN1C2=CC=C(C=C2)C(F)(F)F)C3=C4C=NC=NC4=C(C=C3)C(=O)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BKR51N	5-[[1-(3-Methylphenyl)piperidin-4-yl]amino]quinazoline-8-carboxamide	Investigative	89660736	C21H23N5O	361.4	CC1=CC(=CC=C1)N2CCC(CC2)NC3=C4C=NC=NC4=C(C=C3)C(=O)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BLX0A1	(2S)-5-Carbamimidamido-2-{[(2S)-1-[(2S)-5-carbamimidamido-2-(2-acetamidoacetamido)pentanoyl]pyrrolidin-2-yl]formamido}-N-(4-{[(1S)-2-methyl-1-{[(1S)-1-{[(4-pentylphenyl)methyl]carbamoyl}-2-phenylethyl]carbamoyl}propyl]carbamoyl}phenyl)pentanamide	Investigative	44440122	C54H78N14O8	1051.3	CCCCCC1=CC=C(C=C1)CNC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](C(C)C)NC(=O)C3=CC=C(C=C3)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)C	IC50 = 96000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BM83QO	3-(4-Tert-butylphenyl)-2-pyridin-3-ylimidazo[4,5-b]pyridine	Investigative	60155094	C21H20N4	328.4	CC(C)(C)C1=CC=C(C=C1)N2C3=C(C=CC=N3)N=C2C4=CN=CC=C4	IC50 = 185000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BN24SQ	2-Benzothiazolecarboxamide, 7-nitro-5-[(trifluoromethyl)thio]-, 3-oxide	Investigative	9548013	C9H4F3N3O4S2	339.3	C1=C(C=C(C2=C1[N+](=C(S2)C(=O)N)[O-])[N+](=O)[O-])SC(F)(F)F	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BN8ER3	1H-Indazole-4,7-diamine	Investigative	18963535	C7H8N4	148.17	C1=CC(=C2C(=C1N)C=NN2)N	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BNA26F	(3S,5E)-1-Methyl-3-(pyridin-2-ylmethyl)-5-(pyridin-2-ylmethylidene)piperidin-4-one	Investigative	71720141	C18H19N3O	293.4	CN1C[C@@H](C(=O)/C(=C/C2=CC=CC=N2)/C1)CC3=CC=CC=N3	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BND1G6	Phenylaminoethyl guanidine deriv., 22ea	Investigative	44590365	C39H42N6O	610.8	CC(C)C1=CC=C(C=C1)C2=C(C=CC(=C2)C(=O)NC3=CC=C(C=C3)N(CC4=CC=CC=C4)CC5=CC=CC=C5)NCCN=C(N)N	IC50 = 52000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BNH6U9	6-Chloro-5-(3,5-difluoroanilino)-1H-indazole-4,7-dione	Investigative	44420158	C13H6ClF2N3O2	309.65	C1=C(C=C(C=C1F)F)NC2=C(C(=O)C3=C(C2=O)C=NN3)Cl	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BNL5Q4	2-Methoxy-5-[[4-(1-methylbenzimidazol-2-yl)pyrimidin-2-yl]amino]phenol	Investigative	60166141	C19H17N5O2	347.4	CN1C2=CC=CC=C2N=C1C3=NC(=NC=C3)NC4=CC(=C(C=C4)OC)O	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BP4UJ0	Chembl4170467	Investigative	145955381	C22H19FN4O3S2	470.5	C1CCC2=C(C1)C=CC(=C2)OCC3=NN=C(O3)SCC(=O)NC4=NC5=C(S4)C=C(C=C5)F	IC50 = 98330 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BP6DF3	5-[[2-(3-Chlorophenyl)-2-(dimethylamino)ethyl]amino]quinazoline-8-carboxamide	Investigative	89648102	C19H20ClN5O	369.8	CN(C)C(CNC1=C2C=NC=NC2=C(C=C1)C(=O)N)C3=CC(=CC=C3)Cl	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BP7TI0	5-[2-(3,4-Dichlorophenyl)ethylamino]quinazoline-8-carboxamide	Investigative	89648194	C17H14Cl2N4O	361.2	C1=CC(=C(C=C1CCNC2=C3C=NC=NC3=C(C=C2)C(=O)N)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BPA3E7	1-(1-{[4-(5-Benzyl-6-oxo-3-phenyl-1,6-dihydropyrazin-2-yl)phenyl]methyl}piperidin-4-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-one	Investigative	23647017	C36H33N5O2	567.7	C1CN(CCC1N2C3=CC=CC=C3NC2=O)CC4=CC=C(C=C4)C5=C(N=C(C(=O)N5)CC6=CC=CC=C6)C7=CC=CC=C7	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BPU98D	5-(4-Phenylbutylamino)quinazoline-8-carboxamide	Investigative	89648216	C19H20N4O	320.4	C1=CC=C(C=C1)CCCCNC2=C3C=NC=NC3=C(C=C2)C(=O)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BPV4H6	2-(6-((R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy)quinolin-3-yl)cyclopropanecarboxamide	Investigative	46232556	C21H17Cl2FN2O2	419.3	C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=CC3=CC(=CN=C3C=C2)C4CC4C(=O)N	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BPX05I	6-(3-Chlorophenyl)-8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepine-2,4-diamine	Investigative	44450033	C13H13ClN6	288.73	C1CNC2=NC(=NC(=C2N=C1C3=CC(=CC=C3)Cl)N)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BQ5LG8	(3R,5E)-1-Methyl-3-(pyridin-2-ylmethyl)-5-(pyridin-2-ylmethylidene)piperidin-4-one	Investigative	71718330	C18H19N3O	293.4	CN1C[C@H](C(=O)/C(=C/C2=CC=CC=N2)/C1)CC3=CC=CC=N3	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BQ9O0K	3-[3-[(2-Methoxyphenyl)methyl]imidazo[4,5-b]pyridin-2-yl]pyridin-2-amine	Investigative	60155091	C19H17N5O	331.4	COC1=CC=CC=C1CN2C3=C(C=CC=N3)N=C2C4=C(N=CC=C4)N	IC50 = 58000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BQA48Z	4-[[4-(1-Methylbenzimidazol-2-yl)pyrimidin-2-yl]amino]phenol	Investigative	136206295	C18H15N5O	317.3	CN1C2=CC=CC=C2N=C1C3=NC(=NC=C3)NC4=CC=C(C=C4)O	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BQLU06	6-(4-Methylphenyl)-8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepin-4-amine	Investigative	44450060	C14H15N5	253.3	CC1=CC=C(C=C1)C2=NC3=C(N=CN=C3NCC2)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BQS15H	3-[3-({5-[(E)-2-(Pyridin-4-yl)ethenyl]pyridin-3-yl}oxy)propyl]-1H-indole	Investigative	23646973	C23H21N3O	355.4	C1=CC=C2C(=C1)C(=CN2)CCCOC3=CN=CC(=C3)/C=C/C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BQS51E	Calicoferol A	Investigative	9547698	C27H40O2	396.6	CC1=C(C=C(C=C1)O)CC[C@H]2[C@@H]3CC[C@@H]([C@]3(CCC2=O)C)[C@H](C)/C=C/CC(C)C	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BR3GJ1	5-[4-(4-Fluorophenyl)piperazin-1-yl]quinazoline-8-carboxamide	Investigative	89651661	C19H18FN5O	351.4	C1CN(CCN1C2=CC=C(C=C2)F)C3=C4C=NC=NC4=C(C=C3)C(=O)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BRA71K	6-(4-Chlorophenyl)-8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepine-2,4-diamine	Investigative	10732141	C13H13ClN6	288.73	C1CNC2=NC(=NC(=C2N=C1C3=CC=C(C=C3)Cl)N)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BRI30T	(2S)-1-[(2S)-2-[(2-Acetamidoacetyl)amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1-[4-[[(2S)-1-[[(2S)-1-(benzylamino)-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamoyl]-3-naphthalen-1-ylanilino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide	Investigative	44590348	C59H74N14O8	1107.3	CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC2=CC=CC=C2)NC(=O)C3=C(C=C(C=C3)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)C)C5=CC=CC6=CC=CC=C65	IC50 = 78000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BRKH45	5-(3-Hydroxy-3-phenylpyrrolidin-1-yl)quinazoline-8-carboxamide	Investigative	89649811	C19H18N4O2	334.4	C1CN(CC1(C2=CC=CC=C2)O)C3=C4C=NC=NC4=C(C=C3)C(=O)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BRM92P	(2S)-1-[(2S)-2-[(2-Acetamidoacetyl)amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1-[4-[[(2S)-1-[[(2S)-1-(benzylamino)-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamoyl]-2-methylanilino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide	Investigative	44590345	C50H70N14O8	995.2	CC1=C(C=CC(=C1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)NCC3=CC=CC=C3)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)C	IC50 = 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BRN8J1	N-[3-(2-Pyridin-4-ylpyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide	Investigative	24822704	C25H16F3N5O	459.4	C1=CC(=CC(=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)C3=CC=NC4=CC(=NN34)C5=CC=NC=C5	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BRY4J6	N-(2-((3-(Dimethylamino)propyl)(methyl)amino)-5-(trifluoromethyl)phenyl)-2-fluoro-5-((3-(4-(methylamino)-1,3,5-triazin-2-yl)pyridin-2-yl)oxy)benzamide	Investigative	16109001	C29H30F4N8O2	598.6	CNC1=NC=NC(=N1)C2=C(N=CC=C2)OC3=CC(=C(C=C3)F)C(=O)NC4=C(C=CC(=C4)C(F)(F)F)N(C)CCCN(C)C	IC50 = 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BS25AZ	5-(3-Phenylmethoxypyrrolidin-1-yl)quinazoline-8-carboxamide	Investigative	89647711	C20H20N4O2	348.4	C1CN(CC1OCC2=CC=CC=C2)C3=C4C=NC=NC4=C(C=C3)C(=O)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BS43MZ	3-[5-[(E)-(2-Amino-3,7-dicyano-4,6-dimethyl-cyclopenta[b]pyridin-5-ylidene)methyl]-2-furyl]benzoic acid	Investigative	1131425	C24H16N4O3	408.4	CC\\1=C(C2=C(/C1=C/C3=CC=C(O3)C4=CC(=CC=C4)C(=O)O)C(=C(C(=N2)N)C#N)C)C#N	IC50 = 60200 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BSC1L9	4-[[(2S)-2-Acetamido-5-(diaminomethylideneamino)pentanoyl]amino]-N-[(2S)-1-[[(2S)-1-(benzylamino)-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-2-phenylbenzamide	Investigative	44590350	C42H50N8O5	746.9	CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC2=CC=CC=C2)NC(=O)C3=C(C=C(C=C3)NC(=O)[C@H](CCCN=C(N)N)NC(=O)C)C4=CC=CC=C4	IC50 = 173000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BSEO40	2-Chloro-4-[[4-(1-methylbenzimidazol-2-yl)pyrimidin-2-yl]amino]phenol	Investigative	136206296	C18H14ClN5O	351.8	CN1C2=CC=CC=C2N=C1C3=NC(=NC=C3)NC4=CC(=C(C=C4)O)Cl	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BSK3G0	4-(3-Chlorobenzamido)-3-methyl-1H-thieno[2,3-c]pyrazole-5-carboxamide	Investigative	44405945	C14H11ClN4O2S	334.8	CC1=C2C(=C(SC2=NN1)C(=O)N)NC(=O)C3=CC(=CC=C3)Cl	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BSW19K	(2S)-5-Carbamimidamido-2-acetamido-N-(4-{[(1S)-2-methyl-1-{[(1S)-1-{[(4-pentylphenyl)methyl]carbamoyl}-2-phenylethyl]carbamoyl}propyl]carbamoyl}phenyl)pentanamide	Investigative	44440146	C41H56N8O5	740.9	CCCCCC1=CC=C(C=C1)CNC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](C(C)C)NC(=O)C3=CC=C(C=C3)NC(=O)[C@H](CCCN=C(N)N)NC(=O)C	IC50 = 104000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BTG47Y	Phenylaminoethyl guanidine deriv., 22ca	Investigative	44590364	C42H40N6O	644.8	C1=CC=C(C=C1)CN(CC2=CC=CC=C2)C3=CC=C(C=C3)NC(=O)C4=CC(=C(C=C4)NCCN=C(N)N)C5=CC=C(C=C5)C6=CC=CC=C6	IC50 = 83000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BU3JF8	1-[1-({4-[5-(Butan-2-yl)-6-oxo-3-phenyl-1,6-dihydropyrazin-2-yl]phenyl}methyl)piperidin-4-yl]-2,3-dihydro-1H-1,3-benzodiazol-2-one	Investigative	10152760	C33H35N5O2	533.7	CCC(C)C1=NC(=C(NC1=O)C2=CC=C(C=C2)CN3CCC(CC3)N4C5=CC=CC=C5NC4=O)C6=CC=CC=C6	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BUE85C	5-[(1-Methylpyrrolidin-3-yl)amino]quinazoline-8-carboxamide	Investigative	89648050	C14H17N5O	271.32	CN1CCC(C1)NC2=C3C=NC=NC3=C(C=C2)C(=O)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BUMJ54	4-(1H-Indole-4-ylamino)-5-[3-[2-(4-methylpiperazino)ethoxy]phenyl]pyridine-3-carbonitrile	Investigative	24865437	C27H28N6O	452.6	CN1CCN(CC1)CCOC2=CC=CC(=C2)C3=C(C(=CN=C3)C#N)NC4=CC=CC5=C4C=CN5	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BUQ56V	2-[2-(3-Acetamidophenyl)tetrazol-5-yl]sulfanyl-N-(thiophen-2-ylmethyl)acetamide	Investigative	2810537	C16H16N6O2S2	388.5	CC(=O)NC1=CC(=CC=C1)N2N=C(N=N2)SCC(=O)NCC3=CC=CS3	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BUTQ49	1-[1-({4-[6-(2-Methylpropyl)-5-oxo-3-phenyl-4,5-dihydropyrazin-2-yl]phenyl}methyl)piperidin-4-yl]-2,3-dihydro-1H-1,3-benzodiazol-2-one	Investigative	10218178	C33H35N5O2	533.7	CC(C)CC1=NC(=C(NC1=O)C2=CC=CC=C2)C3=CC=C(C=C3)CN4CCC(CC4)N5C6=CC=CC=C6NC5=O	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BV1AS3	(2S)-5-Carbamimidamido-2-{[(2S)-1-[(2S)-5-carbamimidamido-2-(2-acetamidoacetamido)pentanoyl]pyrrolidin-2-yl]formamido}-N-(4-{[(1S)-1-{[(1S)-1-(hexylcarbamoyl)-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}phenyl)pentanamide	Investigative	44440107	C48H74N14O8	975.2	CCCCCCNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](C(C)C)NC(=O)C2=CC=C(C=C2)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)C	IC50 = 52000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BV9WQ8	N-(4-Ethoxyphenyl)-4-(1-methylbenzimidazol-2-yl)pyrimidin-2-amine	Investigative	60166136	C20H19N5O	345.4	CCOC1=CC=C(C=C1)NC2=NC=CC(=N2)C3=NC4=CC=CC=C4N3C	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BVBC23	3-Methyl-4-phenyl-1H-pyrazole	Investigative	139601	C10H10N2	158.2	CC1=C(C=NN1)C2=CC=CC=C2	IC50 = 80000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BVMW32	N-(4-Methoxyphenyl)-4-(1-methylbenzimidazol-2-yl)pyrimidin-2-amine	Investigative	60166137	C19H17N5O	331.4	CN1C2=CC=CC=C2N=C1C3=NC(=NC=C3)NC4=CC=C(C=C4)OC	IC50 = 75000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BVN9Q7	Phenylaminoethyl guanidine deriv., 22da	Investigative	44590344	C37H35N7O	593.7	C1=CC=C(C=C1)CN(CC2=CC=CC=C2)C3=CC=C(C=C3)NC(=O)C4=CC(=C(C=C4)NCCN=C(N)N)C5=CC=C(C=C5)C#N	IC50 = 78000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BVQC02	2-(3-Hydroxy-4-methoxyanilino)-5,7-dihydro-6H-pyrimido[5,4-d]-[1]benzazepin-6-one	Investigative	16730105	C19H16N4O3	348.4	COC1=C(C=C(C=C1)NC2=NC=C3CC(=O)NC4=CC=CC=C4C3=N2)O	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BVT45D	Methyl 3-methyl-1H-thieno[2,3-c]pyrazole-5-carboxylate	Investigative	44405982	C8H8N2O2S	196.23	CC1=C2C=C(SC2=NN1)C(=O)OC	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BVW47M	1,3-Dimethyl-7-(1-methylbenzimidazol-2-yl)pyrido[2,3-d]pyrimidine-2,4-dione	Investigative	60165992	C17H15N5O2	321.33	CN1C2=CC=CC=C2N=C1C3=NC4=C(C=C3)C(=O)N(C(=O)N4C)C	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BW8Q4E	N-(2,6-Dimethoxypyrimidin-4-yl)-4-(furan-2-ylamino)benzenesulfonamide	Investigative	1380189	C16H16N4O5S	376.4	COC1=NC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)NC3=CC=CO3)OC	IC50 = 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BWD42R	Phenylaminoethyl guanidine deriv., 21bc	Investigative	44590354	C38H40N6O	596.8	CC1=CC(=CC=C1)CN(CC2=CC=CC(=C2)C)C3=CC=C(C=C3)NC(=O)C4=CC(=C(C=C4)NCCN=C(N)N)C5=CC=CC=C5	IC50 = 152000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BWJ84K	4-(4-Chlorobenzamido)-3-methyl-1H-thieno[2,3-c]pyrazole-5-carboxamide	Investigative	44405946	C14H11ClN4O2S	334.8	CC1=C2C(=C(SC2=NN1)C(=O)N)NC(=O)C3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BWSM13	N'-Acryloyl-N'-benzylhydrazinecarboxylic acid tert-butyl ester	Investigative	90645492	C15H20N2O3	276.33	CC(C)(C)OC(=O)NN(CC1=CC=CC=C1)C(=O)C=C	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BX06CM	5-[[(3S)-Pyrrolidin-3-yl]methylamino]quinazoline-8-carboxamide	Investigative	89647822	C14H17N5O	271.32	C1CNC[C@H]1CNC2=C3C=NC=NC3=C(C=C2)C(=O)N	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BX0D7J	Rel-Astrogorgol F	Investigative	54764923	C27H42O2	398.6	CC1=C(C=C(C=C1)O)CC[C@H]2[C@@H]3CC[C@@H]([C@]3(CC[C@@H]2O)C)[C@H](C)/C=C/CC(C)C	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BY06KG	4(3H)-Pyrimidinone,2-[(4-fluorophenyl)amino]-5-[5-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinolinyl]oxy]-2-pyridinyl]-3-methyl-	Investigative	24769780	C33H33FN6O5	612.6	CN1C(=O)C(=CN=C1NC2=CC=C(C=C2)F)C3=NC=C(C=C3)OC4=C5C=C(C(=CC5=NC=C4)OCCCN6CCOCC6)OC	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BY7MP5	5-(1H-Indol-3-yl)-3-(3,4,5-trimethoxyphenyl)-1H-pyrazin-2-one	Investigative	118723185	C21H19N3O4	377.4	COC1=CC(=CC(=C1OC)OC)C2=NC(=CNC2=O)C3=CNC4=CC=CC=C43	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BYB0C2	24-Exomethylenecalicoferol E	Investigative	10047202	C28H42O2	410.6	CC1=C(C=C(C=C1)O)CC[C@H]2[C@@H]3CC[C@@H]([C@]3(CCC2=O)C)[C@H](C)CCC(=C)C(C)C	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BYD96F	Quinazolin-7-yl, 15a	Investigative	44590407	C37H38N8O5	674.7	CC(=O)N[C@@H](CCCN=C(N)N)C(=O)NC1=CC=C(C=C1)C(=O)NC2=CC3=C(C=C2)C(=O)N(C(=O)N3CC4=CC=CC=C4)CC5=CC=CC=C5	IC50 = 112000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BYUD16	2-{[2-(Anilinocarbonyl)anilino]carbonyl}benzoic acid	Investigative	1008649	C21H16N2O4	360.4	C1=CC=C(C=C1)NC(=O)C2=CC=CC=C2NC(=O)C3=CC=CC=C3C(=O)O	IC50 = 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BZ1JP2	Methyl 2-(5-carbamoyl-3-methyl-1H-thieno[2,3-c]pyrazol-4-ylamino)-2-oxoacetate	Investigative	44406047	C10H10N4O4S	282.28	CC1=C2C(=C(SC2=NN1)C(=O)N)NC(=O)C(=O)OC	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BZ4KF9	5-[[4-[3-(Trifluoromethoxy)phenyl]pyrrolidin-3-yl]amino]quinazoline-8-carboxamide	Investigative	78135306	C20H18F3N5O2	417.4	C1C(C(CN1)NC2=C3C=NC=NC3=C(C=C2)C(=O)N)C4=CC(=CC=C4)OC(F)(F)F	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BZ8KL7	(2S)-5-Carbamimidamido-2-acetamido-N-(4-{[(1S)-1-{[(1S)-1-(hexylcarbamoyl)-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}phenyl)pentanamide	Investigative	44440151	C35H52N8O5	664.8	CCCCCCNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](C(C)C)NC(=O)C2=CC=C(C=C2)NC(=O)[C@H](CCCN=C(N)N)NC(=O)C	IC50 = 163000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BZA75I	Acetamide, N-(4-(((2,6-dimethoxy-4-pyrimidinyl)amino)sulfonyl)phenyl)-	Investigative	473359	C14H16N4O5S	352.37	CC(=O)NC1=CC=C(C=C1)S(=O)(=O)NC2=CC(=NC(=N2)OC)OC	IC50 = 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BZH2T9	Tert-butyl (1-(4-(9H-benzo[f]pyrido[2,3-b][1,2,4]triazolo[4,3-d][1,4]diazepin-3-yl)benzoyl)piperidin-4-yl)carbamate	Investigative	136163790	C30H31N7O3	537.6	CC(C)(C)OC(=O)NC1CCN(CC1)C(=O)C2=CC=C(C=C2)C3=NN=C4N3C5=C(NC6=CC=CC=C64)N=CC=C5	IC50 = 56000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	BZR76B	Norlichexanthone	Investigative	5281657	C14H10O5	258.23	CC1=CC(=CC2=C1C(=O)C3=C(C=C(C=C3O2)O)O)O	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	D04PEI	BMS-509744	Investigative	11467730	C32H41N5O4S2	623.8	CC1=CC(=C(C=C1SC2=CN=C(S2)NC(=O)C3=CC=C(C=C3)CNC(C)C(C)(C)C)C(=O)N4CCN(CC4)C(=O)C)OC	IC50 ~ 50000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	D07OXC	AM7	Investigative	11650194	C35H35FN4O5	610.7	CN1C(=NC=C(C1=O)C2=CC(=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OCCCN5CCOCC5)OC)F)CC6=CC=CC=C6	IC50 ~ 100000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	D09XIL	Ro-4396686	Investigative	11396738	C24H24FN5O3	449.5	COC1=CC=C(C=C1)N2CC3=CN=C(N=C3N(C2=O)[C@@H]4CC[C@H](C4)O)NC5=CC=C(C=C5)F	IC50 ~ 125000 nM	Poor binder
T67619	RAC-alpha serine/threonine-protein kinase	D0GD8Y	U0126	Investigative	3006531	C18H16N6S2	380.5	C1=CC=C(C(=C1)N)S/C(=C(/C(=C(/SC2=CC=CC=C2N)\\N)/C#N)\\C#N)/N	IC50 = 60000 nM	Poor binder