TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T68251	Matrix metalloproteinase-2	D00HNB	Clodronate	Approved	25419	CH4Cl2O6P2	244.89	C(P(=O)(O)O)(P(=O)(O)O)(Cl)Cl	IC50 = 145000 nM	Poor binder
T68251	Matrix metalloproteinase-2	D0N6ZA	US9206139, 4	Patented	74221131	C20H24F3N3O3	411.4	CC(C)[C@H](CC1=CC=C(C=C1)C(F)(F)F)C(=O)NC[C@@]2(C(=O)NC(=O)N2)C3CC3	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B05XVW	2-Cinnamamido-N1-hydroxy-N4-propylsuccinamide	Investigative	46228248	C16H21N3O4	319.36	CCCNC(=O)C[C@H](C(=O)NO)NC(=O)/C=C/C1=CC=CC=C1	IC50 = 131000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B0I7JH	2-Cinnamamido-4-(dodecylamino)-4-oxobutanoic acid	Investigative	46228246	C25H38N2O4	430.6	CCCCCCCCCCCCNC(=O)C[C@H](C(=O)O)NC(=O)/C=C/C1=CC=CC=C1	IC50 = 176500 nM	Poor binder
T68251	Matrix metalloproteinase-2	B0I9FV	(R)-5-(4-Bromo-2-fluorobenzylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid	Investigative	44582586	C22H24BrFN2O7	527.3	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NCC2=C(C=C(C=C2)Br)F	IC50 = 76100 nM	Poor binder
T68251	Matrix metalloproteinase-2	B0MS1B	N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-1-(tetrahydro-pyran-4-ylidenemethyl)-ethyl]-formamide	Investigative	23017979	C26H28N2O6S	496.6	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)S(=O)(=O)CC(C=C4CCOCC4)N(C=O)O	IC50 = 60000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B0PJ6F	(S)-N,N-Diethyl-2-(2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetamido)-3-phenyl-propanamide	Investigative	46232491	C24H28N4O3	420.5	CCN(CC)C(=O)[C@H](CC1=CC=CC=C1)NC(=O)CN2C3=CC=CC=C3N=C(C2=O)C	IC50 = 105300 nM	Poor binder
T68251	Matrix metalloproteinase-2	B0QR5V	3-(Hydroxymethyl)-6-(4-hydroxyphenyl)-2-[2-(4-hydroxyphenyl)ethynyl]benzoic acid	Investigative	122179777	C22H16O5	360.4	C1=CC(=CC=C1C#CC2=C(C=CC(=C2C(=O)O)C3=CC=C(C=C3)O)CO)O	IC50 = 85350 nM	Poor binder
T68251	Matrix metalloproteinase-2	B0R2JB	6-[5-(5,7-Dihydroxy-4-oxo-chromen-2-yl)-2-methoxy-phenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one	Investigative	11757331	C31H20O10	552.5	COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O)C4=C(C5=C(C=C4O)OC(=CC5=O)C6=CC=C(C=C6)O)O	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B0V4OK	Naphthalen-1-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445229	C16H11NO3	265.26	C1=CC=C2C(=C1)C=CC=C2OC(=O)C3=CC=CC(=O)N3	IC50 = 109000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B12CRJ	N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]hexanamide	Investigative	22096205	C16H31N3O4	329.43	CCCCC(CN(C=O)O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B15ZCJ	(S)-N-(4-Methoxyphenylsulfonyl)-N-(3-pyridylmethyl)aminobutanoic acid	Investigative	70941086	C17H20N2O5S	364.4	CC[C@@H](C(=O)O)N(CC1=CN=CC=C1)S(=O)(=O)C2=CC=C(C=C2)OC	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B18KLZ	(4S,E)-5-(1,4-Dimethoxy-1,4-dioxobutan-2-ylamino)-4-(3-(3,4-dimethoxyphenyl)acrylamido)-5-oxopentanoic acid	Investigative	44582720	C22H28N2O10	480.5	COC1=C(C=C(C=C1)/C=C/C(=O)N[C@@H](CCC(=O)O)C(=O)NC(CC(=O)OC)C(=O)OC)OC	IC50 = 101500 nM	Poor binder
T68251	Matrix metalloproteinase-2	B1AHC5	4-Phenylbutyl[1-(4-phenylbutyl)-3-(4-phenoxyphenyl)ureidoacetyl]aminoacetohydroximic acid	Investigative	44328283	C37H42N4O5	622.8	C1=CC=C(C=C1)CCCCN(CC(=O)NO)C(=O)CN(CCCCC2=CC=CC=C2)C(=O)NC3=CC=C(C=C3)OC4=CC=CC=C4	IC50 = 52000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B1B7TI	Chembl4208066	Investigative	145976464	C31H22O5	474.5	C1=CC(=CC=C1C2=CC(=CC(=C2C3=CC=C(C=C3)O)C4=CC=C(C=C4)O)C(=O)C5=CC=C(C=C5)O)O	IC50 = 54180 nM	Poor binder
T68251	Matrix metalloproteinase-2	B1CEG0	[(4-Bromophenyl)sulfonyl-phosphonomethyl]phosphonic acid	Investigative	90644157	C7H9BrO8P2S	395.06	C1=CC(=CC=C1S(=O)(=O)C(P(=O)(O)O)P(=O)(O)O)Br	IC50 = 52000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B1DWZ7	(2S)-2-Amino-N-[(3S)-1-[2-(4-fluoroanilino)-2-oxoethyl]-2,6-dioxopiperidin-3-yl]-3-phenylpropanamide	Investigative	49863915	C22H23FN4O4	426.4	C1CC(=O)N(C(=O)[C@H]1NC(=O)[C@H](CC2=CC=CC=C2)N)CC(=O)NC3=CC=C(C=C3)F	IC50 = 122000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B1JOV0	5-[2-[4-(3-Chlorophenyl)phenyl]-2-oxoethyl]-5-hydroxy-1,3-diazinane-2,4,6-trione	Investigative	71451167	C18H13ClN2O5	372.8	C1=CC(=CC(=C1)Cl)C2=CC=C(C=C2)C(=O)CC3(C(=O)NC(=O)NC3=O)O	IC50 = 60000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B1LX9I	(R)-2-(5-(6-Cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-1,2,4-oxadiazole-3-carboxamido)acetic acid	Investigative	10271240	C17H26N4O6	382.4	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C(=O)NCC(=O)O	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B1N2DW	Chembl4213048	Investigative	25212135	C31H22O10	554.5	COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O)C4=C(C5=C(C=C4O)OC(CC5=O)C6=CC=C(C=C6)O)O	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B1OFL3	Hexyl 6-mercaptopicolinate	Investigative	44445270	C12H17NO2S	239.34	CCCCCCOC(=O)C1=CC=CC(=S)N1	IC50 = 85000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B1SJO6	N-[(E)-(4-Dimethylaminophenyl)methyleneamino]-2-(3-methyl-2-oxo-quinoxalin-1-yl)acetamide	Investigative	14616301	C20H21N5O2	363.4	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)N/N=C/C3=CC=C(C=C3)N(C)C	IC50 = 64300 nM	Poor binder
T68251	Matrix metalloproteinase-2	B2AP9E	2-[1-Sec-Butyl-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-N-isopropyl-acetamide	Investigative	44327940	C24H32N4O5	456.5	CCC(C)N(CC(=O)N(CC(=O)NO)C(C)C)C(=O)NC1=CC=C(C=C1)OC2=CC=CC=C2	IC50 = 72000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B2EDN9	3-Methoxybenzyl 6-mercaptopicolinate	Investigative	44445251	C14H13NO3S	275.32	COC1=CC=CC(=C1)COC(=O)C2=CC=CC(=S)N2	IC50 = 90000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B2GW6F	(P-Tolylamino)methylenediphosphonic acid	Investigative	13738810	C8H13NO6P2	281.14	CC1=CC=C(C=C1)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B2I7UA	1-Cinnamyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole	Investigative	44445277	C14H14N4O	254.29	C1COC(=N1)C2=CN(N=N2)C/C=C/C3=CC=CC=C3	IC50 = 149000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B2K1NI	(3R)-6-Cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-1,2,4-oxadiazol-5-yl]-N-hydroxyhexanamide	Investigative	135487604	C18H25N5O5	391.4	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C3=CNC(=O)NC3=O	IC50 = 79600 nM	Poor binder
T68251	Matrix metalloproteinase-2	B2KX4H	(2S)-2-Amino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]-4-methylpentanamide	Investigative	44199512	C15H24N4O4	324.38	CC(C)C[C@@H](C(=O)NC[C@@H]([C@H](C1=CC=C(C=C1)[N+](=O)[O-])O)N)N	IC50 = 142900 nM	Poor binder
T68251	Matrix metalloproteinase-2	B2LIP5	3-Fluorobenzyl 6-mercaptopicolinate	Investigative	44445254	C13H10FNO2S	263.29	C1=CC(=CC(=C1)F)COC(=O)C2=CC=CC(=S)N2	IC50 = 124000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B2MO8B	(3R)-6-Cyclohexyl-N-hydroxy-3-{3-[1-(methylsulfonyl)-4-piperidinyl]-1,2,4-oxadiazol-5-yl}hexanamide	Investigative	44425142	C21H37N5O5S	471.6	CS(=O)(=O)N1CCC(CC1)NCC2=NOC(=N2)[C@H](CCCC3CCCCC3)CC(=O)NO	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B2OI6X	(E)-5-(4-Hydroxyphenyl)-2-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]-3-oxo-N-phenylpent-4-enamide	Investigative	49806131	C26H21NO5	427.4	C1=CC=C(C=C1)NC(=O)C(C(=O)/C=C/C2=CC=C(C=C2)O)C(=O)/C=C/C3=CC=C(C=C3)O	IC50 = 125000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B2RL6A	(2S)-2-Amino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-iodophenyl)propyl]-4-methylpentanamide	Investigative	56661895	C15H24IN3O2	405.27	CC(C)C[C@@H](C(=O)NC[C@@H]([C@H](C1=CC=C(C=C1)I)O)N)N	IC50 = 119500 nM	Poor binder
T68251	Matrix metalloproteinase-2	B2VD5N	Methyl (8S)-7-(4-nitrophenyl)sulfonyl-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylate	Investigative	72737560	C14H16N2O6S3	404.5	COC(=O)[C@@H]1CC2(CN1S(=O)(=O)C3=CC=C(C=C3)[N+](=O)[O-])SCCS2	IC50 = 77930 nM	Poor binder
T68251	Matrix metalloproteinase-2	B2VS5T	(2R)-4-Fluoro-2-[(4-methoxyphenyl)sulfonyl-(pyridin-3-ylmethyl)amino]butanoic acid	Investigative	70941155	C17H19FN2O5S	382.4	COC1=CC=C(C=C1)S(=O)(=O)N(CC2=CN=CC=C2)[C@H](CCF)C(=O)O	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B2XYU7	2-(1-Benzyl-3-naphthalen-1-yl-ureido)-N-sec-butyl-N-hydroxycarbamoylmethyl-acetamide	Investigative	44328295	C26H30N4O4	462.5	CCC(C)N(CC(=O)NO)C(=O)CN(CC1=CC=CC=C1)C(=O)NC2=CC=CC3=CC=CC=C32	IC50 = 110000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B32QID	(S)-2-(2-(3-Methyl-2-oxoquinoxalin-1(2H)-yl)acetamido)-N,3-diphenylpropanamide	Investigative	46233057	C26H24N4O3	440.5	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)N[C@@H](CC3=CC=CC=C3)C(=O)NC4=CC=CC=C4	IC50 = 58140 nM	Poor binder
T68251	Matrix metalloproteinase-2	B35NLF	2,6-Difluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445216	C13H9F2NO3	265.21	C1=CC(=C(C(=C1)F)COC(=O)C2=CC=CC(=O)N2)F	IC50 = 66000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B3ET7X	(3S)-N-[(2S)-1-(Hydroxyamino)-4-methylsulfanyl-1-oxobutan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide;hydrochloride	Investigative	56659953	C15H22ClN3O3S	359.9	CSCC[C@@H](C(=O)NO)NC(=O)[C@@H]1CC2=CC=CC=C2CN1.Cl	IC50 = 166110 nM	Poor binder
T68251	Matrix metalloproteinase-2	B3F2EQ	3-((2-Phenethyl-2H-tetrazol-5-yl)methyl)pyridine	Investigative	44445279	C15H15N5	265.31	C1=CC=C(C=C1)CCN2N=C(N=N2)CC3=CN=CC=C3	IC50 ~ 150000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B3FI7C	N-Hydroxybenzenesulfonamide	Investigative	69033	C6H7NO3S	173.19	C1=CC=C(C=C1)S(=O)(=O)NO	Ki = 70000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B3KE7Z	[(4-Phenylanilino)-phosphono-methyl]phosphonic acid	Investigative	5277465	C13H15NO6P2	343.21	C1=CC=C(C=C1)C2=CC=C(C=C2)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B3NPE5	2,5-Difluorobenzyl 6-mercaptopicolinate	Investigative	44445257	C13H9F2NO2S	281.28	C1=CC(=S)NC(=C1)C(=O)OCC2=C(C=CC(=C2)F)F	IC50 = 79000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B3S5OF	4-Chloro-N-hydroxybenzene-1-sulfonamide	Investigative	352863	C6H6ClNO3S	207.64	C1=CC(=CC=C1S(=O)(=O)NO)Cl	Ki = 70000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B3TM2X	[(2,4-Dichloroanilino)-phosphono-methyl]phosphonic acid	Investigative	5276565	C7H9Cl2NO6P2	336	C1=CC(=C(C=C1Cl)Cl)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B3ZCW8	(R)-5-(4-Chlorophenylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid	Investigative	44582887	C21H23ClN2O7	450.9	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NC2=CC=C(C=C2)Cl	IC50 = 52300 nM	Poor binder
T68251	Matrix metalloproteinase-2	B3ZM4Y	(R)-6-Cyclohexyl-N-hydroxy-3-(3-(piperidine-1-carbonyl)-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	10111132	C20H32N4O4	392.5	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C(=O)N3CCCCC3	IC50 = 74900 nM	Poor binder
T68251	Matrix metalloproteinase-2	B41BIN	2,6-Difluorobenzyl 6-mercaptopicolinate	Investigative	44445256	C13H9F2NO2S	281.28	C1=CC(=C(C(=C1)F)COC(=O)C2=CC=CC(=S)N2)F	IC50 = 66000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B46JHV	Chembl4206592	Investigative	46873064	C27H20O6	440.4	C1=CC(=CC=C1C2=C3C(=C(C=C2)CO)C(=O)OC3(C4=CC=C(C=C4)O)C5=CC=C(C=C5)O)O	IC50 = 53670 nM	Poor binder
T68251	Matrix metalloproteinase-2	B48YSV	US9187406, Curcumin	Investigative	58963267	C21H20O6	368.4	COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)O)CO)O	IC50 = 85000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B49VDF	4-Methoxybenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445210	C14H13NO4	259.26	COC1=CC=C(C=C1)COC(=O)C2=CC=CC(=O)N2	IC50 = 110000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B4A9NL	N-Benzhydryl-N-hydroxycarbamoylmethyl-2-[3-(4-phenoxy-phenyl)-1-(3-phenyl-propyl)-ureido]-acetamide	Investigative	44327780	C39H38N4O5	642.7	C1=CC=C(C=C1)CCCN(CC(=O)N(CC(=O)NO)C(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)NC4=CC=C(C=C4)OC5=CC=CC=C5	IC50 = 200000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B4DIP9	(2R)-2-Amino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]-3-phenylpropanamide	Investigative	56678865	C18H22N4O4	358.4	C1=CC=C(C=C1)C[C@H](C(=O)NC[C@@H]([C@H](C2=CC=C(C=C2)[N+](=O)[O-])O)N)N	IC50 = 67400 nM	Poor binder
T68251	Matrix metalloproteinase-2	B4J1FW	6-Amino-N-[(2R)-2-amino-3-phenylpropyl]caproylamide	Investigative	42645513	C15H25N3O	263.38	C1=CC=C(C=C1)C[C@H](CNC(=O)CCCCCN)N	IC50 = 99700 nM	Poor binder
T68251	Matrix metalloproteinase-2	B4MKA1	N-(p-Fluorobenzenesulfonyl)hydroxylamine	Investigative	12635074	C6H6FNO3S	191.18	C1=CC(=CC=C1F)S(=O)(=O)NO	Ki = 72000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B4NH7Q	4-(4-Methylphenoxy)-N-(4-pyridinylmethyl)benzenecarboxamide	Investigative	4358655	C20H18N2O2	318.4	CC1=CC=C(C=C1)OC2=CC=C(C=C2)C(=O)NCC3=CC=NC=C3	IC50 = 50118.72 nM	Poor binder
T68251	Matrix metalloproteinase-2	B4O5BS	3-Methylbut-2-enyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445201	C11H13NO3	207.23	CC(=CCOC(=O)C1=CC=CC(=O)N1)C	IC50 = 72000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B52MUV	(5S)-4-[2-(1-Adamantyl)ethyl]-5-butyl-1-[(2S)-1-(4-hydroxyphenyl)-3-[(2S)-2-[[(6R)-6-(naphthalen-2-ylmethyl)-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]piperazine-2,3-dione	Investigative	122181996	C49H63N5O5	802.1	CCCC[C@H]1CN(C(=O)C(=O)N1CCC23CC4CC(C2)CC(C4)C3)[C@@H](CC5=CC=C(C=C5)O)CN6CCC[C@H]6CN7[C@@H](CNC(=O)C7=O)CC8=CC9=CC=CC=C9C=C8	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B5B8FZ	Naphthalen-1-yl 6-mercaptopicolinate	Investigative	44445263	C16H11NO2S	281.3	C1=CC=C2C(=C1)C=CC=C2OC(=O)C3=CC=CC(=S)N3	IC50 = 98000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B5DE2F	N-(1,1':4',1''-Terbenzene-4-ylmethyl)-3-hydroxy-4-oxo-6-methyl-4H-pyran-2-carboxamide	Investigative	54724681	C26H21NO4	411.4	CC1=CC(=O)C(=C(O1)C(=O)NCC2=CC=C(C=C2)C3=CC=C(C=C3)C4=CC=CC=C4)O	IC50 ~ 50000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B5J4OW	(R)-5-(6-Cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-N-methyl-N-(pyridin-2-ylmethyl)-1,2,4-oxadiazole-3-carboxamide	Investigative	44571513	C22H31N5O4	429.5	CN(CC1=CC=CC=N1)C(=O)C2=NOC(=N2)[C@H](CCCC3CCCCC3)CC(=O)NO	IC50 = 50500 nM	Poor binder
T68251	Matrix metalloproteinase-2	B5MES1	N-[3,3-Dimethyl-1-oxo-1-(1-phenylethylamino)butan-2-yl]-N'-hydroxy-2-[3-[4-phenyl-3-(trifluoromethyl)phenyl]propyl]butanediamide	Investigative	75018171	C34H40F3N3O4	611.7	CC(C1=CC=CC=C1)NC(=O)C(C(C)(C)C)NC(=O)C(CCCC2=CC(=C(C=C2)C3=CC=CC=C3)C(F)(F)F)CC(=O)NO	IC50 = 51999.6 nM	Poor binder
T68251	Matrix metalloproteinase-2	B5OC0L	CID 50943150	Investigative	50943150	C18H11N3S2	333.4	C1=CC=C2C(=C1)NC(=N2)/C(=C/C3=CC=C(S3)C4=CC=CS4)/C#N	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B5ST1I	Methyl (2S)-2-benzamido-3-(4-phenylmethoxyphenyl)propanoate	Investigative	71452970	C24H23NO4	389.4	COC(=O)[C@H](CC1=CC=C(C=C1)OCC2=CC=CC=C2)NC(=O)C3=CC=CC=C3	IC50 = 67500 nM	Poor binder
T68251	Matrix metalloproteinase-2	B5UYG2	L-Phenylalanyl-N-[(2R)-2-amino-3-phenylpropyl]-L-phenylalaninamide	Investigative	25147768	C27H32N4O2	444.6	C1=CC=C(C=C1)C[C@H](CNC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC3=CC=CC=C3)N)N	IC50 = 182900 nM	Poor binder
T68251	Matrix metalloproteinase-2	B5VX3S	(2S)-2-Amino-N-[(3S)-1-[2-(3-chloro-4-fluoroanilino)-2-oxoethyl]-2,6-dioxopiperidin-3-yl]-3-phenylpropanamide	Investigative	49863954	C22H22ClFN4O4	460.9	C1CC(=O)N(C(=O)[C@H]1NC(=O)[C@H](CC2=CC=CC=C2)N)CC(=O)NC3=CC(=C(C=C3)F)Cl	IC50 = 131000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B68HAL	2-(Benzyl-hydroxycarbamoylmethyl-amino)-N-[2-(4-sulfamoyl-phenyl)-ethyl]-acetamide	Investigative	25178356	C19H24N4O5S	420.5	C1=CC=C(C=C1)CN(CC(=O)NCCC2=CC=C(C=C2)S(=O)(=O)N)CC(=O)NO	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B69LRQ	(R)-4-(4-Carboxy-2-(3,4,5-trimethoxybenzamido)butanamido)-2-hydroxybenzoic acid	Investigative	44582905	C22H24N2O10	476.4	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NC2=CC(=C(C=C2)C(=O)O)O	IC50 = 86300 nM	Poor binder
T68251	Matrix metalloproteinase-2	B6BTQ8	4-(4,5-Dihydrooxazol-2-yl)-1-phenethyl-1H-1,2,3-triazole	Investigative	44445275	C13H14N4O	242.28	C1COC(=N1)C2=CN(N=N2)CCC3=CC=CC=C3	IC50 ~ 150000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B6BZ7Q	Benzyl 6-mercaptopicolinate	Investigative	44445244	C13H11NO2S	245.3	C1=CC=C(C=C1)COC(=O)C2=CC=CC(=S)N2	IC50 = 85000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B6CAZ2	N-[(2R)-2-Amino-3-phenylpropyl]-3,5-dinitrobenzamide	Investigative	42645753	C16H16N4O5	344.32	C1=CC=C(C=C1)C[C@H](CNC(=O)C2=CC(=CC(=C2)[N+](=O)[O-])[N+](=O)[O-])N	IC50 = 100700 nM	Poor binder
T68251	Matrix metalloproteinase-2	B6CO7B	(R)-N-Benzyl-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-N-methyl-1,2,4-oxadiazole-3-carboxamide	Investigative	10180993	C23H32N4O4	428.5	CN(CC1=CC=CC=C1)C(=O)C2=NOC(=N2)[C@H](CCCC3CCCCC3)CC(=O)NO	IC50 = 81800 nM	Poor binder
T68251	Matrix metalloproteinase-2	B6D5XV	(S)-N-(4-Methoxyphenylsulfonyl)-N-(3-pyridylmethyl)-aminopent-4-enoic acid	Investigative	71465468	C18H20N2O5S	376.4	COC1=CC=C(C=C1)S(=O)(=O)N(CC2=CN=CC=C2)[C@@H](CC=C)C(=O)O	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B6FYQ5	N6-[(Benzyloxy)carbonyl]-N2-cinnamoyl-L-lysine	Investigative	44586532	C23H26N2O5	410.5	C1=CC=C(C=C1)COC(=O)NCCCC[C@@H](C(=O)O)NC(=O)/C=C/C2=CC=CC=C2	IC50 = 50500 nM	Poor binder
T68251	Matrix metalloproteinase-2	B6HBX9	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(phenylsulfonyl)amino]carbonyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	9890632	C21H28N4O6S	464.5	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C(=O)NS(=O)(=O)C3=CC=CC=C3	IC50 = 92000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B6J1EV	6-Mercapto-pyridine-2-carboxylic acid 4-methyl-benzyl ester	Investigative	44445248	C14H13NO2S	259.329	CC1=CC=C(C=C1)COC(=O)C2=CC=CC(=S)N2	IC50 = 98000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B6O4DQ	(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]acrylamide	Investigative	53374826	C10H8F3NO2	231.17	C1=CC(=CC=C1/C=C/C(=O)NO)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B6VU7L	(2S)-2-Amino-N-[(2R)-1-[[(2S,3S)-2-amino-3-hydroxy-3-(4-iodophenyl)propyl]amino]-1-oxo-3-phenylpropan-2-yl]-4-methylpentanamide	Investigative	56682293	C24H33IN4O3	552.4	CC(C)C[C@@H](C(=O)N[C@H](CC1=CC=CC=C1)C(=O)NC[C@@H]([C@H](C2=CC=C(C=C2)I)O)N)N	IC50 = 86600 nM	Poor binder
T68251	Matrix metalloproteinase-2	B71NZU	[(4S,5S)-2-((Z)-4-Phenyl-buta-1,3-dienyl)-5-vinyl-4,5-dihydro-oxazol-4-yl]-methanol	Investigative	44394681	C16H17NO2	255.31	C=C[C@H]1[C@@H](N=C(O1)/C=C\\C=C\\C2=CC=CC=C2)CO	Ki = 153000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B72TWU	(2S)-2-Amino-3-methyl-N-[(2R)-2-amino-3-phenylpropyl]propionamide	Investigative	44588219	C14H23N3O	249.35	CC(C)[C@@H](C(=O)NC[C@@H](CC1=CC=CC=C1)N)N	IC50 = 151400 nM	Poor binder
T68251	Matrix metalloproteinase-2	B78GIR	4-Thiouracil	Investigative	2734394	C4H4N2OS	128.15	C1=CNC(=O)NC1=S	IC50 = 121000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B7HAY0	Phenethyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445205	C14H13NO3	243.26	C1=CC=C(C=C1)CCOC(=O)C2=CC=CC(=O)N2	IC50 = 69000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B7JFU8	N-Butyl-2-[1-[2-(4-fluoro-phenyl)-ethyl]-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-acetamide	Investigative	44328296	C29H33FN4O5	536.6	CCCCN(CC(=O)NO)C(=O)CN(CCC1=CC=C(C=C1)F)C(=O)NC2=CC=C(C=C2)OC3=CC=CC=C3	IC50 = 51000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B7L5OB	4-Bromo-N-hydroxybenzenesulfonamide	Investigative	121255	C6H6BrNO3S	252.09	C1=CC(=CC=C1S(=O)(=O)NO)Br	Ki = 65000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B7QJE6	Schembl21751149	Investigative	78426757	C48H59N5O5	786	C1C[C@H](N(C1)C[C@H](CC2=CC=CC=C2)N3C[C@@H](N(C(=O)C3=O)CCC45CC6CC(C4)CC(C6)C5)CC7=CC=C(C=C7)O)CN8[C@H](CNC(=O)C8=O)CC9=CC=CC=C9	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B7WNT8	4-Phenoxybutyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445212	C16H17NO4	287.31	C1=CC=C(C=C1)OCCCCOC(=O)C2=CC=CC(=O)N2	IC50 = 90000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B7Z6GY	1-Cyclohexenyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole	Investigative	44445271	C11H14N4O	218.26	C1CCC(=CC1)N2C=C(N=N2)C3=NCCO3	IC50 ~ 150000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B83QWM	(2S)-2-Amino-N-[(2S,3S)-2-amino-3-(4-aminophenyl)-3-hydroxypropyl]-3-(4-hydroxyphenyl)propanamide	Investigative	56675664	C18H24N4O3	344.4	C1=CC(=CC=C1C[C@@H](C(=O)NC[C@@H]([C@H](C2=CC=C(C=C2)N)O)N)N)O	IC50 = 111300 nM	Poor binder
T68251	Matrix metalloproteinase-2	B86QXD	(2S)-N-[(2S,3S)-2-Amino-3-hydroxy-3-(4-iodophenyl)propyl]-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-4-methylpentanamide	Investigative	56682295	C24H33IN4O3	552.4	CC(C)C[C@@H](C(=O)NC[C@@H]([C@H](C1=CC=C(C=C1)I)O)N)NC(=O)[C@@H](CC2=CC=CC=C2)N	IC50 = 52700 nM	Poor binder
T68251	Matrix metalloproteinase-2	B87DNV	(Hydroxyamino)(4-iodophenyl)sulfone	Investigative	5220706	C6H6INO3S	299.09	C1=CC(=CC=C1S(=O)(=O)NO)I	Ki = 72000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B89SNP	N-[(E)-Benzylideneamino]-2-(3-methyl-2-oxo-quinoxalin-1-yl)acetamide	Investigative	14616298	C18H16N4O2	320.3	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)N/N=C/C3=CC=CC=C3	IC50 = 67010 nM	Poor binder
T68251	Matrix metalloproteinase-2	B8ARM3	3-Fluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445214	C13H10FNO3	247.22	C1=CC(=CC(=C1)F)COC(=O)C2=CC=CC(=O)N2	IC50 = 70000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B8H6ZF	6-Mercapto-pyridine-2-carboxylic acid biphenyl-4-ylmethyl ester	Investigative	44445265	C19H15NO2S	321.4	C1=CC=C(C=C1)C2=CC=C(C=C2)COC(=O)C3=CC=CC(=S)N3	IC50 = 110000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B8JE1T	3-(4-(2-Oxo-2H-chromen-3-yl)-2-thioxo-2,3-dihydro-1H-imidazol-1-yl)benzoic acid	Investigative	4085085	C19H12N2O4S	364.4	C1=CC=C2C(=C1)C=C(C(=O)O2)C3=CN(C(=S)N3)C4=CC=CC(=C4)C(=O)O	IC50 = 67000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B8OCE9	N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-1-(tetrahydro-thiopyran-4-ylidenemethyl)-ethyl]-formamide	Investigative	44330132	C26H28N2O5S2	512.6	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)S(=O)(=O)CC(C=C4CCSCC4)N(C=O)O	IC50 = 55000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B8QZ0Y	(2S)-2,6-Amino-N-[(2R)-2-amino-3-phenylpropyl]caproylamide	Investigative	42645288	C15H26N4O	278.39	C1=CC=C(C=C1)C[C@H](CNC(=O)[C@H](CCCCN)N)N	IC50 = 99700 nM	Poor binder
T68251	Matrix metalloproteinase-2	B8SX1O	2-[1-Tert-Butyl-3-(4-phenoxy-phenyl)-ureido]-N-cyclohexylmethyl-N-hydroxycarbamoylmethyl-acetamide	Investigative	44327915	C28H38N4O5	510.6	CC(C)(C)N(CC(=O)N(CC1CCCCC1)CC(=O)NO)C(=O)NC2=CC=C(C=C2)OC3=CC=CC=C3	IC50 = 150000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B8U0SC	2-Chlorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445222	C13H10ClNO3	263.67	C1=CC=C(C(=C1)COC(=O)C2=CC=CC(=O)N2)Cl	IC50 = 69000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B91PLB	1,10-Phenanthroline	Investigative	1318	C12H8N2	180.2	C1=CC2=C(C3=C(C=CC=N3)C=C2)N=C1	IC50 = 70000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B95JGO	(S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-(methylamino)-5-oxopentanoic acid	Investigative	44582686	C17H22N2O6	350.4	CNC(=O)[C@H](CCC(=O)O)NC(=O)/C=C/C1=CC(=C(C=C1)OC)OC	IC50 = 159100 nM	Poor binder
T68251	Matrix metalloproteinase-2	B95QFN	2-Cinnamamido-N1-hydroxy-N4-isopropylsuccinamide	Investigative	46228266	C16H21N3O4	319.36	CC(C)NC(=O)C[C@H](C(=O)NO)NC(=O)/C=C/C1=CC=CC=C1	IC50 = 166600 nM	Poor binder
T68251	Matrix metalloproteinase-2	B95ZRL	4-Fluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445215	C13H10FNO3	247.22	C1=CC(=O)NC(=C1)C(=O)OCC2=CC=C(C=C2)F	IC50 = 71000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B9DW4I	[(4S,5S)-2-(4-Nitro-phenyl)-5-vinyl-4,5-dihydro-oxazol-4-yl]-methanol	Investigative	44394886	C12H12N2O4	248.23	C=C[C@H]1[C@@H](N=C(O1)C2=CC=C(C=C2)[N+](=O)[O-])CO	Ki ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B9O2AL	(S,E)-5-(3-Chlorophenylamino)-4-(3-(3,4-dimethoxyphenyl)acrylamido)-5-oxopentanoic acid	Investigative	44582647	C22H23ClN2O6	446.9	COC1=C(C=C(C=C1)/C=C/C(=O)N[C@@H](CCC(=O)O)C(=O)NC2=CC(=CC=C2)Cl)OC	IC50 = 120800 nM	Poor binder
T68251	Matrix metalloproteinase-2	B9Q2PE	(Dibutylamino)carbonylphosphonic acid	Investigative	11207122	C9H20NO4P	237.23	CCCCN(CCCC)C(=O)P(=O)(O)O	IC50 = 50000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B9UIW0	[Pentyl[1-(3-phenylpropyl)-3-(4-phenoxyphenyl)ureidoacetyl]amino]acetohydroximic acid	Investigative	44328246	C31H38N4O5	546.7	CCCCCN(CC(=O)NO)C(=O)CN(CCCC1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)OC3=CC=CC=C3	IC50 = 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	B9ZI8U	(2S)-N-[(2S,3S)-2-Amino-3-hydroxy-3-(4-nitrophenyl)propyl]-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-4-methylpentanamide	Investigative	56661759	C24H33N5O5	471.5	CC(C)C[C@@H](C(=O)NC[C@@H]([C@H](C1=CC=C(C=C1)[N+](=O)[O-])O)N)NC(=O)[C@@H](CC2=CC=CC=C2)N	IC50 = 105600 nM	Poor binder
T68251	Matrix metalloproteinase-2	BA39YM	Phenethyl 6-mercaptopicolinate	Investigative	44445245	C14H13NO2S	259.329	C1=CC=C(C=C1)CCOC(=O)C2=CC=CC(=S)N2	IC50 = 119000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BA3M4C	N-[(Hydroxyamino)carbonyl]-L-leucyl-Lphenylalanine methylamide	Investigative	24881246	C17H26N4O4	350.4	CC(C)C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NC)NC(=O)NO	IC50 = 60000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BA87EI	Methyl (2S)-2-benzamido-3-[4-(2-phenylethoxy)phenyl]propanoate	Investigative	71458326	C25H25NO4	403.5	COC(=O)[C@H](CC1=CC=C(C=C1)OCCC2=CC=CC=C2)NC(=O)C3=CC=CC=C3	IC50 = 74600 nM	Poor binder
T68251	Matrix metalloproteinase-2	BAJ49I	(1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-3-(2-trifluoromethoxy-phenylsulfanyl)-propyl]-phosphinic acid	Investigative	44341652	C38H38F3N4O7PS	782.8	C1=CC=C(C=C1)CC(NC(=O)OCC2=CC=CC=C2)P(=O)(CC(CSC3=CC=CC=C3OC(F)(F)F)C(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)N)O	Ki = 200000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BAXL35	N-[1-(4'-Cyano-4-biphenylyloxymethyl)-2-(2,5-dioxo-3,4,4-trimethylimidazolidine-1-yl)ethyl]formhydroxamic acid	Investigative	9932731	C23H24N4O5	436.5	CC1(C(=O)N(C(=O)N1C)CC(COC2=CC=C(C=C2)C3=CC=C(C=C3)C#N)N(C=O)O)C	IC50 = 58000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BB5R1E	(R)-5-(6-Cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-N-isopropyl-1,2,4-oxadiazole-3-carboxamide	Investigative	9947332	C18H30N4O4	366.5	CC(C)NC(=O)C1=NOC(=N1)[C@H](CCCC2CCCCC2)CC(=O)NO	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BB9JA3	But-2-ynyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445202	C10H9NO3	191.18	CC#CCOC(=O)C1=CC=CC(=O)N1	IC50 = 70000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BBNA52	(2S,3S,4R)-4-(4,5-Dihydroxy-3-methoxy-6-methyloxan-2-yl)oxy-8,10-bis(dimethylamino)-2,5,7-trihydroxy-3-methoxy-2-methyl-3,4-dihydrotetracene-1,6,11-trione	Investigative	44326171	C31H38N2O12	630.6	CC1C(C(C(C(O1)O[C@H]2[C@@H]([C@](C(=O)C3=CC4=C(C(=C23)O)C(=O)C5=C(C4=O)C(=CC(=C5O)N(C)C)N(C)C)(C)O)OC)OC)O)O	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BBV2R3	N6-[(Benzyloxy)carbonyl]-N2-(2,4-dichlorobenzoyl)-N1-hydroxy-L-lysinamide	Investigative	25022465	C21H23Cl2N3O5	468.3	C1=CC=C(C=C1)COC(=O)NCCCC[C@@H](C(=O)NO)NC(=O)C2=C(C=C(C=C2)Cl)Cl	IC50 = 170000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BBY86P	Benzenemethanesulfonamide, N-hydroxy-	Investigative	23645541	C7H9NO3S	187.22	C1=CC=C(C=C1)CS(=O)(=O)NO	Ki = 73000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BC10VU	(2S)-2-Amino-N-[(2R)-1-[[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]amino]-1-oxo-3-phenylpropan-2-yl]-4-methylpentanamide	Investigative	56665195	C24H33N5O5	471.5	CC(C)C[C@@H](C(=O)N[C@H](CC1=CC=CC=C1)C(=O)NC[C@@H]([C@H](C2=CC=C(C=C2)[N+](=O)[O-])O)N)N	IC50 = 173100 nM	Poor binder
T68251	Matrix metalloproteinase-2	BC2KM9	Benzyl-3-(2-((S)-3-((S)-2-amino-3-phenylpropanamido)-2,6-dioxopiperidin-1-yl)acetamido)propanoate	Investigative	49863563	C26H30N4O6	494.5	C1CC(=O)N(C(=O)[C@H]1NC(=O)[C@@H](CC2=CC=CC=C2)N)CC(=O)NCCC(=O)OCC3=CC=CC=C3	IC50 = 127000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BC36TM	Cyclobutyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445200	C10H11NO3	193.2	C1CC(C1)OC(=O)C2=CC=CC(=O)N2	IC50 = 66000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BC6T0Q	(5S)-5-Benzyl-1-[(2R)-1-[(2S)-2-[[(6R)-6-benzyl-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-cyclohexylpropan-2-yl]-4-(2-phenylethyl)piperazine-2,3-dione	Investigative	122181999	C44H55N5O4	717.9	C1CCC(CC1)C[C@H](CN2CCC[C@H]2CN3[C@@H](CNC(=O)C3=O)CC4=CC=CC=C4)N5C[C@@H](N(C(=O)C5=O)CCC6=CC=CC=C6)CC7=CC=CC=C7	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BC74NY	2-[2-[(E)-(5-Oxo-2-sulfanylideneimidazolidin-4-ylidene)methyl]phenoxy]acetic acid	Investigative	703233	C12H10N2O4S	278.29	C1=CC=C(C(=C1)/C=C/2\\C(=O)NC(=S)N2)OCC(=O)O	IC50 = 61000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BC8RU5	(R)-5-(4-Chloro-2-fluorobenzylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid	Investigative	44582550	C22H24ClFN2O7	482.9	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NCC2=C(C=C(C=C2)Cl)F	IC50 = 52800 nM	Poor binder
T68251	Matrix metalloproteinase-2	BCE62Z	(2Z,NE)-N-benzylidene-4-(3,4-dimethoxyphenyl)-2-(phenylimino)thiazol-3(2H)-amine	Investigative	6882342	C24H21N3O2S	415.5	COC1=C(C=C(C=C1)C2=CSC(=NC3=CC=CC=C3)N2/N=C/C4=CC=CC=C4)OC	IC50 = 120000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BCIL03	(Hydroxysulfamoyl)dimethylamine	Investigative	12447203	C2H8N2O3S	140.16	CN(C)S(=O)(=O)NO	Ki ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BCJL25	(2R)-2-Amino-N-[(3S)-1-[2-[[2-(hydroxyamino)-2-oxoethyl]amino]-2-oxoethyl]-2,6-dioxopiperidin-3-yl]-3-phenylpropanamide	Investigative	49863622	C18H23N5O6	405.4	C1CC(=O)N(C(=O)[C@H]1NC(=O)[C@@H](CC2=CC=CC=C2)N)CC(=O)NCC(=O)NO	IC50 = 141000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BCL65G	3-Methyl-2-oxo-quinoxaline-1(2h)-acetohydrazide	Investigative	14616290	C11H12N4O2	232.24	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)NN	IC50 = 98020 nM	Poor binder
T68251	Matrix metalloproteinase-2	BD20NB	2-[[4-[(3,5-Dibromophenyl)methoxy]phenyl]sulfonylamino]acetic acid	Investigative	72714084	C15H13Br2NO5S	479.1	C1=CC(=CC=C1OCC2=CC(=CC(=C2)Br)Br)S(=O)(=O)NCC(=O)O	IC50 = 125000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BD2WO1	N-Tert-Butyl-N-hydroxycarbamoylmethyl-2-[1-isopropyl-3-(4-phenoxy-phenyl)-ureido]-acetamide	Investigative	44327960	C24H32N4O5	456.5	CC(C)N(CC(=O)N(CC(=O)NO)C(C)(C)C)C(=O)NC1=CC=C(C=C1)OC2=CC=CC=C2	IC50 = 155000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BDJ0T9	(R)-5-(3-Iodobenzylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid	Investigative	44582549	C22H25IN2O7	556.3	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NCC2=CC(=CC=C2)I	IC50 = 76800 nM	Poor binder
T68251	Matrix metalloproteinase-2	BDJ7N6	4-(4,5-Dihydrooxazol-2-yl)-1-(3-phenylpropyl)-1H-1,2,3-triazole	Investigative	44445276	C14H16N4O	256.3	C1COC(=N1)C2=CN(N=N2)CCCC3=CC=CC=C3	IC50 ~ 150000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BDX8N2	[4-(Trifluoromethyl)phenyl]methyl 6-oxo-1H-pyridine-2-carboxylate	Investigative	46905989	C14H10F3NO3	297.23	C1=CC(=O)NC(=C1)C(=O)OCC2=CC=C(C=C2)C(F)(F)F	IC50 = 112000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BDY8G1	Methyl (2S)-2-[(4-methylbenzoyl)amino]-3-(4-phenylmethoxyphenyl)propanoate	Investigative	71452971	C25H25NO4	403.5	CC1=CC=C(C=C1)C(=O)N[C@@H](CC2=CC=C(C=C2)OCC3=CC=CC=C3)C(=O)OC	IC50 = 83700 nM	Poor binder
T68251	Matrix metalloproteinase-2	BE2AB4	N-Heptyl-N-hydroxycarbamoylmethyl-2-[1-pentyl-3-(4-phenoxy-phenyl)-ureido]-acetamide	Investigative	44327916	C29H42N4O5	526.7	CCCCCCCN(CC(=O)NO)C(=O)CN(CCCCC)C(=O)NC1=CC=C(C=C1)OC2=CC=CC=C2	IC50 = 60000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BE56OY	Furan-2-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445239	C10H7NO4	205.17	C1=CC(=O)NC(=C1)C(=O)OC2=CC=CO2	IC50 = 111000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BE89GB	(R)-5-(4-Bromophenylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid	Investigative	44582888	C21H23BrN2O7	495.3	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NC2=CC=C(C=C2)Br	IC50 = 54400 nM	Poor binder
T68251	Matrix metalloproteinase-2	BE94AJ	4-Chlorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445223	C13H10ClNO3	263.67	C1=CC(=O)NC(=C1)C(=O)OCC2=CC=C(C=C2)Cl	IC50 = 69000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BED10O	(2S)-2-[[2-(3-Methyl-2-oxoquinoxalin-1-yl)acetyl]amino]-3-phenyl-N-propylpropanamide	Investigative	46232418	C23H26N4O3	406.5	CCCNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CN2C3=CC=CC=C3N=C(C2=O)C	IC50 = 56600 nM	Poor binder
T68251	Matrix metalloproteinase-2	BEPO61	(S)-Benzyl-2-(2-((S)-3-((S)-2-amino-3-phenylpropanamido)-2,6-dioxopiperidin-1-yl)acetamido)-4-methylpentanoate	Investigative	49863562	C29H36N4O6	536.6	CC(C)C[C@@H](C(=O)OCC1=CC=CC=C1)NC(=O)CN2C(=O)CC[C@@H](C2=O)NC(=O)[C@H](CC3=CC=CC=C3)N	IC50 = 121000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BEW6D2	2,4,5-Trifluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445220	C13H8F3NO3	283.2	C1=CC(=O)NC(=C1)C(=O)OCC2=CC(=C(C=C2F)F)F	IC50 = 86000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BF09QZ	(4S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-(3-(4-fluorophenyl)-1-methoxy-1-oxopropan-2-ylamino)-5-oxopentanoic acid	Investigative	44582746	C26H29FN2O8	516.5	COC1=C(C=C(C=C1)/C=C/C(=O)N[C@@H](CCC(=O)O)C(=O)NC(CC2=CC=C(C=C2)F)C(=O)OC)OC	IC50 = 76500 nM	Poor binder
T68251	Matrix metalloproteinase-2	BF0D9I	[Anilino(phosphono)methyl]phosphonic acid	Investigative	450256	C7H11NO6P2	267.11	C1=CC=C(C=C1)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BF0HQ4	Thiophen-2-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445235	C10H7NO3S	221.23	C1=CC(=O)NC(=C1)C(=O)OC2=CC=CS2	IC50 = 73000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BF12NZ	4-Phenoxybenzyl 6-mercaptopicolinate	Investigative	44445268	C19H15NO3S	337.4	C1=CC=C(C=C1)OC2=CC=C(C=C2)COC(=O)C3=CC=CC(=S)N3	IC50 = 93000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BF6SU7	5-{(1R)-4-Cyclohexyl-1-[2-(hydroxyamino)-2-oxoethyl]butyl}-N,N-dimethyl-1,2,4-oxadiazole-3-carboxamide	Investigative	9924640	C17H28N4O4	352.4	CN(C)C(=O)C1=NOC(=N1)[C@H](CCCC2CCCCC2)CC(=O)NO	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BFBK27	Naphthalen-2-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445230	C16H11NO3	265.26	C1=CC=C2C=C(C=CC2=C1)OC(=O)C3=CC=CC(=O)N3	IC50 = 125000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BFH2P0	[2-Methyl-1-[[4-(5-methylthiophen-2-yl)phenyl]sulfonylamino]propyl]phosphonic acid	Investigative	127029508	C15H20NO5PS2	389.4	CC1=CC=C(S1)C2=CC=C(C=C2)S(=O)(=O)NC(C(C)C)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BFZ48U	3-Hydroxy-4H-pyran-4-thione	Investigative	11355488	C5H4O2S	128.15	C1=COC=C(C1=S)O	IC50 = 76000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BG18OL	Acetic acid 3-acetoxy-5-methoxy-2-methyl-6-(3,10,12-trihydroxy-2-methoxy-3-methyl-4,6,11-trioxo-1,2,3,4,6,11-hexahydro-naphthacen-1-yloxy)-tetrahydro-pyran-4-yl ester	Investigative	44326187	C31H32O14	628.6	CC1C(C(C(C(O1)O[C@H]2[C@@H]([C@](C(=O)C3=CC4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5O)(C)O)OC)OC)OC(=O)C)OC(=O)C	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BG47FV	(4R)-5-Oxo-5-[4-(1,3-thiazol-2-ylsulfamoyl)anilino]-4-[(3,4,5-trimethoxybenzoyl)amino]pentanoic acid	Investigative	44582868	C24H26N4O9S2	578.6	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NC2=CC=C(C=C2)S(=O)(=O)NC3=NC=CS3	IC50 = 55300 nM	Poor binder
T68251	Matrix metalloproteinase-2	BG47RP	(S,E)-5-(4-Bromophenylamino)-4-(3-(3,4-dimethoxyphenyl)acrylamido)-5-oxopentanoic acid	Investigative	44582588	C22H23BrN2O6	491.3	COC1=C(C=C(C=C1)/C=C/C(=O)N[C@@H](CCC(=O)O)C(=O)NC2=CC=C(C=C2)Br)OC	IC50 = 71200 nM	Poor binder
T68251	Matrix metalloproteinase-2	BG4QJ1	(S)-N-(4-Methoxyphenylsulfonyl)-N-(3-pyridylmethyl)-2-amino-4-fluoropent-4-enoic acid	Investigative	71465466	C18H19FN2O5S	394.4	COC1=CC=C(C=C1)S(=O)(=O)N(CC2=CN=CC=C2)[C@@H](CC(=C)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BG7P3F	Cyclohexanamine;2-methylpropylcarbamoylphosphonic acid	Investigative	9882151	C11H25N2O4P	280.3	CC(C)CNC(=O)P(=O)(O)O.C1CCC(CC1)N	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BG7SM6	(2R)-2-Amino-N-[(2S)-1-[[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]amino]-3-hydroxy-1-oxopropan-2-yl]-3-phenylpropanamide	Investigative	56658263	C21H27N5O6	445.5	C1=CC=C(C=C1)C[C@H](C(=O)N[C@@H](CO)C(=O)NC[C@@H]([C@H](C2=CC=C(C=C2)[N+](=O)[O-])O)N)N	IC50 = 110100 nM	Poor binder
T68251	Matrix metalloproteinase-2	BG9U0C	Cyclohexyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445203	C12H15NO3	221.25	C1CCC(CC1)OC(=O)C2=CC=CC(=O)N2	IC50 = 101000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BGF30U	(2R)-N-Hydroxy-2-[[1-[2-[2-[2-[2-[4-[[[(2R)-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]-(4-methoxyphenyl)sulfonylamino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methyl-(4-methoxyphenyl)sulfonylamino]-3-methylbutanamide	Investigative	70692916	C38H56N10O13S2	925	CC(C)[C@H](C(=O)NO)N(CC1=CN(N=N1)CCOCCOCCOCCN2C=C(N=N2)CN([C@H](C(C)C)C(=O)NO)S(=O)(=O)C3=CC=C(C=C3)OC)S(=O)(=O)C4=CC=C(C=C4)OC	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BGN3P0	2-(2-(4-Methoxyphenylsulfonyl)phenyl)acetic Acid	Investigative	44479700	C15H14O5S	306.3	COC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2CC(=O)O	IC50 = 58000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BGPR53	N-Hydroxy-4-methylbenzenesulfonamide	Investigative	10081163	C7H9NO3S	187.22	CC1=CC=C(C=C1)S(=O)(=O)NO	Ki = 77000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BGTX61	(R)-5-(2-Nicotinoylhydrazinyl)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid	Investigative	44582875	C21H24N4O8	460.4	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NNC(=O)C2=CN=CC=C2	IC50 = 114900 nM	Poor binder
T68251	Matrix metalloproteinase-2	BGV36J	(4S,5S)-2-p-Tolyl-5-vinyl-4,5-dihydro-oxazole-4-thiol	Investigative	44394703	C12H13NOS	219.3	CC1=CC=C(C=C1)C2=N[C@H]([C@@H](O2)C=C)S	Ki = 88000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BGXT10	2-Bromobenzyl 6-mercaptopicolinate	Investigative	44445262	C13H10BrNO2S	324.19	C1=CC=C(C(=C1)COC(=O)C2=CC=CC(=S)N2)Br	IC50 = 108000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BGY1M0	1-[2-[4-(4-Cyanophenyl)phenoxy]ethyl]-3-hydroxyurea	Investigative	44286483	C16H15N3O3	297.31	C1=CC(=CC=C1C#N)C2=CC=C(C=C2)OCCNC(=O)NO	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BH60GQ	(R)-5-Oxo-5-(2-(thiazole-2-carbonyl)hydrazinyl)-4-(3,4,5-trimethoxybenzamido)pentanoic acid	Investigative	44582874	C19H22N4O8S	466.5	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NNC(=O)C2=NC=CS2	IC50 = 169400 nM	Poor binder
T68251	Matrix metalloproteinase-2	BH7FI5	Naphthalen-2-yl 6-mercaptopicolinate	Investigative	44445264	C16H11NO2S	281.3	C1=CC=C2C=C(C=CC2=C1)OC(=O)C3=CC=CC(=S)N3	IC50 = 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BHJA06	(2S)-2-Amino-4-methylthio-N-[(2R)-2-amino-3-phenylpropyl]butyramide	Investigative	42645511	C14H23N3OS	281.42	CSCC[C@@H](C(=O)NC[C@@H](CC1=CC=CC=C1)N)N	IC50 = 112100 nM	Poor binder
T68251	Matrix metalloproteinase-2	BHK5T0	Thiophen-3-yl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445237	C10H7NO3S	221.23	C1=CC(=O)NC(=C1)C(=O)OC2=CSC=C2	IC50 = 65000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BHKF38	Epicatechin 3-O-(3-O-methylgallate)	Investigative	467296	C23H20O10	456.4	COC1=CC(=CC(=C1O)O)C(=O)O[C@@H]2CC3=C(C=C(C=C3O[C@@H]2C4=CC(=C(C=C4)O)O)O)O	IC50 = 88000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BHOA54	(4S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-(1-methoxy-3-methyl-1-oxobutan-2-ylamino)-5-oxopentanoic acid	Investigative	44582719	C22H30N2O8	450.5	CC(C)C(C(=O)OC)NC(=O)[C@H](CCC(=O)O)NC(=O)/C=C/C1=CC(=C(C=C1)OC)OC	IC50 = 76800 nM	Poor binder
T68251	Matrix metalloproteinase-2	BI3VS2	(S)-Benzyl-2-(2-(3-((S)-2-amino-3-phenylpropanamido)-2,6-dioxopiperidin-1-yl)acetamido)propanoate	Investigative	49863560	C26H30N4O6	494.5	C[C@@H](C(=O)OCC1=CC=CC=C1)NC(=O)CN2C(=O)CC[C@@H](C2=O)NC(=O)[C@H](CC3=CC=CC=C3)N	IC50 = 129000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BI4C0G	Methyl (2S)-2-[(4-methylbenzoyl)amino]-3-[4-(2-phenylethoxy)phenyl]propanoate	Investigative	71449332	C26H27NO4	417.5	CC1=CC=C(C=C1)C(=O)N[C@@H](CC2=CC=C(C=C2)OCCC3=CC=CC=C3)C(=O)OC	IC50 = 85500 nM	Poor binder
T68251	Matrix metalloproteinase-2	BI73TH	4-Fluorobenzyl 6-mercaptopicolinate	Investigative	44445255	C13H10FNO2S	263.29	C1=CC(=S)NC(=C1)C(=O)OCC2=CC=C(C=C2)F	IC50 = 108000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BI74SE	(2R)-N-[(2S)-3,3-Dimethyl-1-oxo-1-[[(1R)-1-phenylethyl]amino]butan-2-yl]-N'-hydroxy-2-[3-[4-phenyl-3-(trifluoromethyl)phenyl]propyl]butanediamide	Investigative	44369163	C34H40F3N3O4	611.7	C[C@H](C1=CC=CC=C1)NC(=O)[C@H](C(C)(C)C)NC(=O)[C@H](CCCC2=CC(=C(C=C2)C3=CC=CC=C3)C(F)(F)F)CC(=O)NO	IC50 = 52000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BI7Y5L	1,1,1-Trifluoro-N-hydroxymethanesulfonamide	Investigative	23644662	CH2F3NO3S	165.09	C(F)(F)(F)S(=O)(=O)NO	Ki ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BIBX94	CID 78426619	Investigative	78426619	C44H55N5O5	733.9	C1CCC(CC1)C[C@H](CN2CCC[C@H]2CN3[C@H](CNC(=O)C3=O)CC4=CC=CC=C4)N5C[C@@H](N(C(=O)C5=O)CCC6=CC=CC=C6)CC7=CC=C(C=C7)O	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BID20Z	Benzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445204	C13H11NO3	229.23	C1=CC=C(C=C1)COC(=O)C2=CC=CC(=O)N2	IC50 = 65000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BIDO53	Thiophen-3-yl 6-mercaptopicolinate	Investigative	44445269	C10H7NO2S2	237.3	C1=CC(=S)NC(=C1)C(=O)OC2=CSC=C2	IC50 = 77000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BIFP05	2-Amino-5-(4-((thiiran-2-ylmethyl)sulfonyl)phenoxy)phenol	Investigative	54757202	C15H15NO4S2	337.4	C1C(S1)CS(=O)(=O)C2=CC=C(C=C2)OC3=CC(=C(C=C3)N)O	Ki = 78000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BIK0A1	Chembl4211480	Investigative	145965508	C21H14O5	346.3	C1C2=C(C(=C(C=C2)C3=CC=C(C=C3)O)C(=O)C4=CC=C(C=C4)O)C(=O)O1	IC50 = 81210 nM	Poor binder
T68251	Matrix metalloproteinase-2	BISO86	(4S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-(1-methoxy-1-oxopropan-2-ylamino)-5-oxopentanoic acid	Investigative	44582718	C20H26N2O8	422.4	CC(C(=O)OC)NC(=O)[C@H](CCC(=O)O)NC(=O)/C=C/C1=CC(=C(C=C1)OC)OC	IC50 = 83200 nM	Poor binder
T68251	Matrix metalloproteinase-2	BIV97T	(2S)-2-Amino-N-[(3S)-1-[2-(2-fluoroanilino)-2-oxoethyl]-2,6-dioxopiperidin-3-yl]-3-phenylpropanamide	Investigative	49863934	C22H23FN4O4	426.4	C1CC(=O)N(C(=O)[C@H]1NC(=O)[C@H](CC2=CC=CC=C2)N)CC(=O)NC3=CC=CC=C3F	IC50 = 62700 nM	Poor binder
T68251	Matrix metalloproteinase-2	BIZX05	N-[(E)-1-(2-Chlorophenyl)ethylideneamino]-2-(3-methyl-2-oxoquinoxalin-1-yl)acetamide	Investigative	127030239	C19H17ClN4O2	368.8	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)N/N=C(\\C)/C3=CC=CC=C3Cl	IC50 = 112260 nM	Poor binder
T68251	Matrix metalloproteinase-2	BJ0LR6	Thioacetic acid S-[(4S,5S)-2-((E)-styryl)-5-vinyl-4,5-dihydro-oxazol-4-yl] ester	Investigative	44394645	C15H15NO2S	273.4	CC(=O)S[C@H]1[C@@H](OC(=N1)/C=C/C2=CC=CC=C2)C=C	Ki ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BJ1LV0	(5S)-5-Benzyl-1-[(2R)-1-cyclohexyl-3-[(2S)-2-[[(6S)-2,3-dioxo-6-propylpiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]-4-(2-phenylethyl)piperazine-2,3-dione	Investigative	122181998	C40H55N5O4	669.9	CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]2CCCN2C[C@@H](CC3CCCCC3)N4C[C@@H](N(C(=O)C4=O)CCC5=CC=CC=C5)CC6=CC=CC=C6	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BJ27VX	Isopropyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445199	C9H11NO3	181.19	CC(C)OC(=O)C1=CC=CC(=O)N1	IC50 = 67000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BJM5H0	(2E)-2-(1H-Benzimidazol-2-yl)-3-(3-iodo-4-methoxyphenyl)prop-2-enenitrile	Investigative	5941957	C17H12IN3O	401.2	COC1=C(C=C(C=C1)/C=C(\\C#N)/C2=NC3=CC=CC=C3N2)I	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BJW19F	3-((2-Benzyl-2H-tetrazol-5-yl)methyl)pyridine	Investigative	44445278	C14H13N5	251.29	C1=CC=C(C=C1)CN2N=C(N=N2)CC3=CN=CC=C3	IC50 ~ 150000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BJZL58	4-Chloroanilinomethylenebisphosphonic acid	Investigative	15629940	C7H10ClNO6P2	301.56	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)Cl	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BK1GF6	(S,E)-5-(4-Chlorophenylamino)-4-(3-(3,4-dimethoxyphenyl)acrylamido)-5-oxopentanoic acid	Investigative	44582568	C22H23ClN2O6	446.9	COC1=C(C=C(C=C1)/C=C/C(=O)N[C@@H](CCC(=O)O)C(=O)NC2=CC=C(C=C2)Cl)OC	IC50 = 59900 nM	Poor binder
T68251	Matrix metalloproteinase-2	BK2NS9	Pentyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445240	C11H15NO3	209.24	CCCCCOC(=O)C1=CC=CC(=O)N1	IC50 = 103000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BK4UV8	N-Benzhydryl-2-[1-benzhydryl-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-acetamide	Investigative	44328316	C43H38N4O5	690.8	C1=CC=C(C=C1)C(C2=CC=CC=C2)N(CC(=O)NO)C(=O)CN(C(C3=CC=CC=C3)C4=CC=CC=C4)C(=O)NC5=CC=C(C=C5)OC6=CC=CC=C6	IC50 = 50000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BK95NA	3,4-Dichloroanilinomethylenebisphosphonic acid	Investigative	24866945	C7H9Cl2NO6P2	336	C1=CC(=C(C=C1NC(P(=O)(O)O)P(=O)(O)O)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BKFL26	3-Bromobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445225	C13H10BrNO3	308.13	C1=CC(=CC(=C1)Br)COC(=O)C2=CC=CC(=O)N2	IC50 = 68000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BKG9M5	4-(4,5-Dihydrooxazol-2-yl)-1-hexyl-1H-1,2,3-triazole	Investigative	44445272	C11H18N4O	222.29	CCCCCCN1C=C(N=N1)C2=NCCO2	IC50 ~ 150000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BKM83T	4-Chlorobenzyl 6-mercaptopicolinate	Investigative	44445261	C13H10ClNO2S	279.74	C1=CC(=S)NC(=C1)C(=O)OCC2=CC=C(C=C2)Cl	IC50 = 96000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BKPV14	N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylidenemethyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide	Investigative	44330147	C30H37N3O5S	551.7	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)S(=O)(=O)CC(C=C4CCN(CC4)CC(C)C)N(C=O)O	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BKQZ26	2-(2-(3-((S)-2-Amino-3-phenylpropanamido)-2,6-dioxopiperidin-1-yl)acetamido)acetic acid	Investigative	49863590	C18H22N4O6	390.4	C1CC(=O)N(C(=O)[C@H]1NC(=O)[C@H](CC2=CC=CC=C2)N)CC(=O)NCC(=O)O	IC50 = 107000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BKS4B1	(E)-5-(4-Hydroxy-3-methoxyphenyl)-2-[(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl]-3-oxo-N-phenylpent-4-enamide	Investigative	49806130	C28H25NO7	487.5	COC1=C(C=CC(=C1)/C=C/C(=O)C(C(=O)NC2=CC=CC=C2)C(=O)/C=C/C3=CC(=C(C=C3)O)OC)O	IC50 = 85000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BL2F0S	6-Oxo-1,6-dihydro-pyridine-2-carboxylic acid 4-methyl-benzyl ester	Investigative	44445206	C14H13NO3	243.26	CC1=CC=C(C=C1)COC(=O)C2=CC=CC(=O)N2	IC50 = 73000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BLHG74	N-Hydroxycarbamoylmethyl-2-[3-(4-phenoxy-phenyl)-1-(1,2,3,4-tetrahydro-naphthalen-1-yl)-ureido]-N-(1,2,3,4-tetrahydro-naphthalen-1-yl)-acetamide	Investigative	44328317	C37H38N4O5	618.7	C1CC(C2=CC=CC=C2C1)N(CC(=O)NO)C(=O)CN(C3CCCC4=CC=CC=C34)C(=O)NC5=CC=C(C=C5)OC6=CC=CC=C6	IC50 = 60000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BM3O5C	(2R)-2-Amino-N-[(2S)-3-[[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]amino]-2-hydroxy-3-oxopropyl]-3-phenylpropanamide	Investigative	56665196	C21H27N5O6	445.5	C1=CC=C(C=C1)C[C@H](C(=O)NC[C@@H](C(=O)NC[C@@H]([C@H](C2=CC=C(C=C2)[N+](=O)[O-])O)N)O)N	IC50 = 108900 nM	Poor binder
T68251	Matrix metalloproteinase-2	BM7PR2	(2S)-N-Butyl-2-[[2-(3-methyl-2-oxoquinoxalin-1-yl)acetyl]amino]-3-phenylpropanamide	Investigative	46232490	C24H28N4O3	420.5	CCCCNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CN2C3=CC=CC=C3N=C(C2=O)C	IC50 = 106000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BMC90G	N-[(E)-(4-Chlorophenyl)methyleneamino]-2-(3-methyl-2-oxo-quinoxalin-1-yl)acetamide	Investigative	14616300	C18H15ClN4O2	354.8	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)N/N=C/C3=CC=C(C=C3)Cl	IC50 = 81010 nM	Poor binder
T68251	Matrix metalloproteinase-2	BMI8C2	Isopropyl 6-mercaptopicolinate	Investigative	44445241	C9H11NO2S	197.26	CC(C)OC(=O)C1=CC=CC(=S)N1	IC50 ~ 150000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BN39PI	(2S)-2-Amino-N-[(3S)-1-[2-(3-chloroanilino)-2-oxoethyl]-2,6-dioxopiperidin-3-yl]-3-phenylpropanamide	Investigative	49863933	C22H23ClN4O4	442.9	C1CC(=O)N(C(=O)[C@H]1NC(=O)[C@H](CC2=CC=CC=C2)N)CC(=O)NC3=CC(=CC=C3)Cl	IC50 = 60400 nM	Poor binder
T68251	Matrix metalloproteinase-2	BN7RG4	1,5-Dimethyl-5-(4-phenoxyphenyl)hexahydropyrimidine-2,4,6-trione	Investigative	44384994	C18H16N2O4	324.3	CC1(C(=O)NC(=O)N(C1=O)C)C2=CC=C(C=C2)OC3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BN9ZG7	(2S)-3-Amino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]-2-hydroxypropanamide	Investigative	56661758	C12H18N4O5	298.3	C1=CC(=CC=C1[C@@H]([C@H](CNC(=O)[C@H](CN)O)N)O)[N+](=O)[O-]	IC50 = 100100 nM	Poor binder
T68251	Matrix metalloproteinase-2	BNEM74	2,5-Difluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445217	C13H9F2NO3	265.21	C1=CC(=O)NC(=C1)C(=O)OCC2=C(C=CC(=C2)F)F	IC50 = 70000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BNF4H3	(2R)-2-Amino-N-[(2S,3S)-2-amino-3-(4-aminophenyl)-3-hydroxypropyl]-3-phenylpropanamide	Investigative	56672135	C18H24N4O2	328.4	C1=CC=C(C=C1)C[C@H](C(=O)NC[C@@H]([C@H](C2=CC=C(C=C2)N)O)N)N	IC50 = 149200 nM	Poor binder
T68251	Matrix metalloproteinase-2	BNFP12	(S,E)-5-(3,5-Difluorophenylamino)-4-(3-(3,4-dimethoxyphenyl)acrylamido)-5-oxopentanoic acid	Investigative	44582644	C22H22F2N2O6	448.4	COC1=C(C=C(C=C1)/C=C/C(=O)N[C@@H](CCC(=O)O)C(=O)NC2=CC(=CC(=C2)F)F)OC	IC50 = 116300 nM	Poor binder
T68251	Matrix metalloproteinase-2	BNH40K	trans-2-Aminocyclohexylcarbamoylphosphonic acid	Investigative	24807817	C7H15N2O4P	222.18	C1CC[C@H]([C@@H](C1)N)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BNOK60	2-Fluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445213	C13H10FNO3	247.22	C1=CC=C(C(=C1)COC(=O)C2=CC=CC(=O)N2)F	IC50 = 71000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BNOR68	N-[(E)-(2,4-Dimethoxyphenyl)methylideneamino]-2-(3-methyl-2-oxoquinoxalin-1-yl)acetamide	Investigative	127033875	C20H20N4O4	380.4	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)N/N=C/C3=C(C=C(C=C3)OC)OC	IC50 = 74910 nM	Poor binder
T68251	Matrix metalloproteinase-2	BNP8H6	(2R,3R)-N-(2-(4-Benzylthiophen-2-yl)ethyl)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide	Investigative	46184724	C27H30N2O4S	478.6	C1CC(N(C1)C(=O)[C@@H]([C@H](C(=O)NCCC2=CC(=CS2)CC3=CC=CC=C3)O)O)C4=CC=CC=C4	Ki ~ 50000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BNTY08	(E)-3-((2-Cinnamyl-2H-tetrazol-5-yl)methyl)pyridine	Investigative	44445281	C16H15N5	277.32	C1=CC=C(C=C1)/C=C/CN2N=C(N=N2)CC3=CN=CC=C3	IC50 ~ 150000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BNU1Q2	Cyclohexyl 6-mercaptopicolinate	Investigative	44445243	C12H15NO2S	237.32	C1CCC(CC1)OC(=O)C2=CC=CC(=S)N2	IC50 = 73000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BNYG94	(S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-(2-fluorophenylamino)-5-oxopentanoic acid	Investigative	44582645	C22H23FN2O6	430.4	COC1=C(C=C(C=C1)/C=C/C(=O)N[C@@H](CCC(=O)O)C(=O)NC2=CC=CC=C2F)OC	IC50 = 71400 nM	Poor binder
T68251	Matrix metalloproteinase-2	BO2DW9	(R)-4-(4-Carboxy-2-(3,4,5-trimethoxybenzamido)butanamido)benzoic acid	Investigative	44582904	C22H24N2O9	460.4	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NC2=CC=C(C=C2)C(=O)O	IC50 = 71200 nM	Poor binder
T68251	Matrix metalloproteinase-2	BO2H4C	[1-[[4-[5-(Methoxymethyl)thiophen-2-yl]phenyl]sulfonylamino]-2-methylpropyl]phosphonic acid	Investigative	127029510	C16H22NO6PS2	419.5	CC(C)C(NS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(S2)COC)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BO54DN	N-[1-(Phenylthiomethyl)-2-(4'-cyano-4-biphenylyloxy)ethyl]formhydroxamic acid	Investigative	21700038	C23H20N2O3S	404.5	C1=CC=C(C=C1)SCC(COC2=CC=C(C=C2)C3=CC=C(C=C3)C#N)N(C=O)O	IC50 = 160000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BO5DJ0	N'-[2-(3-Methyl-2-oxo-quinoxalin-1-yl)acetyl]-2-phenyl-acetohydrazide	Investigative	46212112	C19H18N4O3	350.4	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)NNC(=O)CC3=CC=CC=C3	IC50 = 159390 nM	Poor binder
T68251	Matrix metalloproteinase-2	BO9W8V	N-Benzyl-2-[1-cyclohexylmethyl-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-acetamide	Investigative	44328279	C31H36N4O5	544.6	C1CCC(CC1)CN(CC(=O)N(CC2=CC=CC=C2)CC(=O)NO)C(=O)NC3=CC=C(C=C3)OC4=CC=CC=C4	IC50 = 125000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BO9WE6	4-(4,5-Dihydrooxazol-2-yl)-1-heptyl-1H-1,2,3-triazole	Investigative	44445273	C12H20N4O	236.31	CCCCCCCN1C=C(N=N1)C2=NCCO2	IC50 ~ 150000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BOL2C9	N-Methyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-acetamide	Investigative	10610500	C6H9N5O2S2	247.3	CNC(=O)CNC(=O)NC1=NNC(=S)S1	Ki ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BOVG57	{(R)-3-[(S)-2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethylcarbamoyl]-5-methyl-hexanoylaminooxy}-acetic acid methyl ester	Investigative	10647658	C23H32N4O6	460.5	CC(C)C[C@H](CC(=O)NOCC(=O)OC)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)NC	Ki = 71000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BP7Q2C	(R)-5-(3-Chloro-4-fluorophenylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid	Investigative	44582547	C21H22ClFN2O7	468.9	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NC2=CC(=C(C=C2)F)Cl	IC50 = 107200 nM	Poor binder
T68251	Matrix metalloproteinase-2	BP9QX0	(R)-5-(2,5-Dichlorophenylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid	Investigative	44582907	C21H22Cl2N2O7	485.3	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NC2=C(C=CC(=C2)Cl)Cl	IC50 = 122400 nM	Poor binder
T68251	Matrix metalloproteinase-2	BPJ18L	(2S)-N-[(2S,3S)-2-Amino-3-hydroxy-3-(4-nitrophenyl)propyl]-2-[[(2S)-3-amino-2-hydroxypropanoyl]amino]-4-methylpentanamide	Investigative	56682179	C18H29N5O6	411.5	CC(C)C[C@@H](C(=O)NC[C@@H]([C@H](C1=CC=C(C=C1)[N+](=O)[O-])O)N)NC(=O)[C@H](CN)O	IC50 = 83900 nM	Poor binder
T68251	Matrix metalloproteinase-2	BPJ60S	(2S)-2-Amino-3-thiol-N-[(2R)-2-amino-3-phenylpropyl]propionamide	Investigative	44588253	C12H19N3OS	253.37	C1=CC=C(C=C1)C[C@H](CNC(=O)[C@H](CS)N)N	IC50 = 78800 nM	Poor binder
T68251	Matrix metalloproteinase-2	BPM2J0	3-Methoxybenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445209	C14H13NO4	259.26	COC1=CC=CC(=C1)COC(=O)C2=CC=CC(=O)N2	IC50 = 70000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BQ2HP5	N-[4-[4-(Thiiran-2-ylmethylsulfonyl)phenoxy]phenyl]acetamide	Investigative	15941553	C17H17NO4S2	363.5	CC(=O)NC1=CC=C(C=C1)OC2=CC=C(C=C2)S(=O)(=O)CC3CS3	Ki = 110000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BQ97ZC	3,5-Difluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445218	C13H9F2NO3	265.21	C1=CC(=O)NC(=C1)C(=O)OCC2=CC(=CC(=C2)F)F	IC50 = 69000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BQI1T0	(3R)-6-Cyclohexyl-N-hydroxy-3-[3-(3-pyridinylmethyl)-1,2,4-oxadiazol-5-yl]hexanamide	Investigative	16748901	C20H28N4O3	372.5	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)CC3=CN=CC=C3	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BQK5W3	4-Methoxybenzyl 6-mercaptopicolinate	Investigative	44445252	C14H13NO3S	275.32	COC1=CC=C(C=C1)COC(=O)C2=CC=CC(=S)N2	IC50 = 91000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BQKA74	Ethyl 5-(5-methoxycarbonyl-2-methylpyrazol-3-yl)-1H-indole-2-carboxylate	Investigative	56850409	C17H17N3O4	327.33	CCOC(=O)C1=CC2=C(N1)C=CC(=C2)C3=CC(=NN3C)C(=O)OC	IC50 = 83000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BQN7T5	N-[1-[4-(4-Cyanophenyl)phenoxy]propan-2-yl]-N-hydroxyformamide	Investigative	10402302	C17H16N2O3	296.32	CC(COC1=CC=C(C=C1)C2=CC=C(C=C2)C#N)N(C=O)O	IC50 = 76000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BQX1W6	Cinnamyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445228	C15H13NO3	255.27	C1=CC=C(C=C1)/C=C/COC(=O)C2=CC=CC(=O)N2	IC50 = 90000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BR6BS8	N-[4-[[4-[2-(2,5-Dimethylpyridin-4-yl)ethyl]piperidin-1-yl]sulfonylmethyl]oxan-4-yl]-N-hydroxyformamide	Investigative	54580051	C21H33N3O5S	439.6	CC1=CC(=C(C=N1)C)CCC2CCN(CC2)S(=O)(=O)CC3(CCOCC3)N(C=O)O	IC50 = 61000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BRC53V	N-[(1S,2S)-2-Hydroxycyclopentyl]-4-phenoxybenzenesulfonamide	Investigative	71682917	C17H19NO4S	333.4	C1C[C@@H]([C@H](C1)O)NS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3	Ki = 50000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BRCZ16	1-Benzyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole	Investigative	44445274	C12H12N4O	228.25	C1COC(=N1)C2=CN(N=N2)CC3=CC=CC=C3	IC50 ~ 150000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BRTE39	Benzo[d][1,3]dioxol-5-ylmethyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445231	C14H11NO5	273.24	C1OC2=C(O1)C=C(C=C2)COC(=O)C3=CC=CC(=O)N3	IC50 = 107000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BS17YT	(S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-(2-methoxy-2-oxoethylamino)-5-oxopentanoic acid	Investigative	44582717	C19H24N2O8	408.4	COC1=C(C=C(C=C1)/C=C/C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)OC)OC	IC50 = 79600 nM	Poor binder
T68251	Matrix metalloproteinase-2	BS25YO	N-Sec-Butyl-2-[1-butyl-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-acetamide	Investigative	44327961	C25H34N4O5	470.6	CCCCN(CC(=O)N(CC(=O)NO)C(C)CC)C(=O)NC1=CC=C(C=C1)OC2=CC=CC=C2	IC50 = 54000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BS4KA8	Chembl4206956	Investigative	145975682	C33H24O4	484.5	C1=CC=C(C=C1)/C(=C\\C(=O)C2=CC=C(C=C2)O)/C3=C(C=CC=C3C4=CC=C(C=C4)O)C5=CC=C(C=C5)O	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BS81KI	(2S)-2-Amino-N-[(3S)-1-[2-(4-bromoanilino)-2-oxoethyl]-2,6-dioxopiperidin-3-yl]-3-phenylpropanamide	Investigative	49863953	C22H23BrN4O4	487.3	C1CC(=O)N(C(=O)[C@H]1NC(=O)[C@H](CC2=CC=CC=C2)N)CC(=O)NC3=CC=C(C=C3)Br	IC50 = 71600 nM	Poor binder
T68251	Matrix metalloproteinase-2	BSD4C0	Cyclobutyl 6-mercaptopicolinate	Investigative	44445242	C10H11NO2S	209.27	C1CC(C1)OC(=O)C2=CC=CC(=S)N2	IC50 ~ 150000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BSD50Z	4-(Trifluoromethyl)benzyl 6-mercaptopicolinate	Investigative	44445250	C14H10F3NO2S	313.3	C1=CC(=S)NC(=C1)C(=O)OCC2=CC=C(C=C2)C(F)(F)F	IC50 = 125000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BSJ45U	Morpholin-4-ylcarbonylphosphonic acid	Investigative	44328189	C5H10NO5P	195.11	C1COCCN1C(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BSP3A8	Schembl22225166	Investigative	17853548	C17H20O9	368.3	COC(=O)C1(CC(C(C(C1)OC(=O)/C=C/C2=CC(=C(C=C2)O)O)O)O)O	IC50 = 64190 nM	Poor binder
T68251	Matrix metalloproteinase-2	BT16SP	Benzyl 6-Benzyl-5,7-Dioxo-6,7-Dihydro-5h-[1,3]thiazolo[3,2-C]pyrimidine-2-Carboxylate	Investigative	9896504	C21H16N2O4S	392.4	C1=CC=C(C=C1)CN2C(=O)C=C3N(C2=O)C=C(S3)C(=O)OCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BTOX16	(2S)-N-Hydroxy-1-[(3S)-1,2,3,4-tetrahydroisoquinoline-3-carbonyl]pyrrolidine-2-carboxamide;hydrochloride	Investigative	56677119	C15H20ClN3O3	325.79	C1C[C@H](N(C1)C(=O)[C@@H]2CC3=CC=CC=C3CN2)C(=O)NO.Cl	IC50 = 157420 nM	Poor binder
T68251	Matrix metalloproteinase-2	BTQF19	N'-[2-(3-Methyl-2-oxo-quinoxalin-1-yl)acetyl]benzohydrazide	Investigative	46212861	C18H16N4O3	336.3	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)NNC(=O)C3=CC=CC=C3	IC50 = 187410 nM	Poor binder
T68251	Matrix metalloproteinase-2	BTZ16E	N4-(4-Chlorophenyl)-2-cinnamamido-N1-hydroxysuccinamide	Investigative	46228308	C19H18ClN3O4	387.8	C1=CC=C(C=C1)/C=C/C(=O)N[C@H](CC(=O)NC2=CC=C(C=C2)Cl)C(=O)NO	IC50 = 196600 nM	Poor binder
T68251	Matrix metalloproteinase-2	BUE50B	2-(3-Methyl-2-oxoquinoxalin-1-yl)-N-[(E)-1-(4-nitrophenyl)ethylideneamino]acetamide	Investigative	127031462	C19H17N5O4	379.4	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)N/N=C(\\C)/C3=CC=C(C=C3)[N+](=O)[O-]	IC50 = 90810 nM	Poor binder
T68251	Matrix metalloproteinase-2	BUK1T6	3-(Trifluoromethyl)benzyl 6-mercaptopicolinate	Investigative	44445249	C14H10F3NO2S	313.3	C1=CC(=CC(=C1)C(F)(F)F)COC(=O)C2=CC=CC(=S)N2	IC50 = 110000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BV0CE6	Methyl (E)-5-(4-hydroxyphenyl)-2-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]-3-oxopent-4-enoate	Investigative	49806133	C21H18O6	366.4	COC(=O)C(C(=O)/C=C/C1=CC=C(C=C1)O)C(=O)/C=C/C2=CC=C(C=C2)O	IC50 = 70000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BV1HA4	Hydroxysulfonamide 48	Investigative	23644663	CH2Cl3NO3S	214.5	C(S(=O)(=O)NO)(Cl)(Cl)Cl	Ki ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BV1SF0	N-Hydroxycarbamoylmethyl-2-[1-(1-methyl-butyl)-3-(4-phenoxy-phenyl)-ureido]-N-pentyl-acetamide	Investigative	44327939	C27H38N4O5	498.6	CCCCCN(CC(=O)NO)C(=O)CN(C(C)CCC)C(=O)NC1=CC=C(C=C1)OC2=CC=CC=C2	IC50 = 160000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BV3LN7	(2S)-2-Amino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]-3-(4-hydroxyphenyl)propanamide	Investigative	56682178	C18H22N4O5	374.4	C1=CC(=CC=C1C[C@@H](C(=O)NC[C@@H]([C@H](C2=CC=C(C=C2)[N+](=O)[O-])O)N)N)O	IC50 = 61300 nM	Poor binder
T68251	Matrix metalloproteinase-2	BVBQ62	2,6-Dichloro-N'-[2-(3-methyl-2-oxo-quinoxalin-1-yl)acetyl]benzohydrazide	Investigative	46212114	C18H14Cl2N4O3	405.2	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)NNC(=O)C3=C(C=CC=C3Cl)Cl	IC50 = 58220 nM	Poor binder
T68251	Matrix metalloproteinase-2	BVI84X	(2S)-N-[(2S,3S)-2-Amino-3-(4-aminophenyl)-3-hydroxypropyl]-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-4-methylpentanamide	Investigative	56678975	C24H35N5O3	441.6	CC(C)C[C@@H](C(=O)NC[C@@H]([C@H](C1=CC=C(C=C1)N)O)N)NC(=O)[C@@H](CC2=CC=CC=C2)N	IC50 = 94000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BW0FL1	(2S)-2,6-Diamino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]hexanamide	Investigative	56665194	C15H25N5O4	339.39	C1=CC(=CC=C1[C@@H]([C@H](CNC(=O)[C@H](CCCCN)N)N)O)[N+](=O)[O-]	IC50 = 84300 nM	Poor binder
T68251	Matrix metalloproteinase-2	BW1KQ0	4-Phenoxybutyl 6-mercaptopicolinate	Investigative	44445253	C16H17NO3S	303.4	C1=CC=C(C=C1)OCCCCOC(=O)C2=CC=CC(=S)N2	IC50 = 63000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BW21UB	(2R)-2-Amino-N-[(2R)-1-[[(2S,3S)-2-amino-3-hydroxy-3-(4-iodophenyl)propyl]amino]-1-oxo-3-phenylpropan-2-yl]-3-phenylpropanamide	Investigative	56682294	C27H31IN4O3	586.5	C1=CC=C(C=C1)C[C@H](C(=O)N[C@H](CC2=CC=CC=C2)C(=O)NC[C@@H]([C@H](C3=CC=C(C=C3)I)O)N)N	IC50 = 107100 nM	Poor binder
T68251	Matrix metalloproteinase-2	BW4I1K	N-Hydroxycarbamoylmethyl-N-(1-methyl-butyl)-2-[3-(4-phenoxy-phenyl)-1-(3-phenyl-propyl)-ureido]-acetamide	Investigative	44327801	C31H38N4O5	546.7	CCCC(C)N(CC(=O)NO)C(=O)CN(CCCC1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)OC3=CC=CC=C3	IC50 = 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BWF9E5	(2S)-2-Amino-N-[(2S,3S)-2-amino-3-(4-aminophenyl)-3-hydroxypropyl]-4-methylpentanamide	Investigative	56678867	C15H26N4O2	294.39	CC(C)C[C@@H](C(=O)NC[C@@H]([C@H](C1=CC=C(C=C1)N)O)N)N	IC50 = 119300 nM	Poor binder
T68251	Matrix metalloproteinase-2	BWH48N	(2S)-2-Amino-4-methyl-N-[(2R)-2-amino-3-phenylpropyl]valeramide	Investigative	42645280	C15H25N3O	263.38	CC(C)C[C@@H](C(=O)NC[C@@H](CC1=CC=CC=C1)N)N	IC50 = 170200 nM	Poor binder
T68251	Matrix metalloproteinase-2	BWR10G	Perfluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445221	C13H6F5NO3	319.18	C1=CC(=O)NC(=C1)C(=O)OCC2=C(C(=C(C(=C2F)F)F)F)F	IC50 = 64000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BX6RI7	N-Hydroxycarbamoylmethyl-N-(1-methyl-butyl)-2-[3-naphthalen-2-yl-1-(1,2,3,4-tetrahydro-naphthalen-1-yl)-ureido]-acetamide	Investigative	44327914	C30H36N4O4	516.6	CCCC(C)N(CC(=O)NO)C(=O)CN(C1CCCC2=CC=CC=C12)C(=O)NC3=CC4=CC=CC=C4C=C3	IC50 = 120000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BX7RZ0	3-((2-(3-Phenylpropyl)-2H-tetrazol-5-yl)methyl)pyridine	Investigative	44445280	C16H17N5	279.34	C1=CC=C(C=C1)CCCN2N=C(N=N2)CC3=CN=CC=C3	IC50 ~ 150000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BX95AE	2-Bromobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445224	C13H10BrNO3	308.13	C1=CC=C(C(=C1)COC(=O)C2=CC=CC(=O)N2)Br	IC50 = 57000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BXG5J0	Ubenimex	Investigative	72172	C16H24N2O4	308.37	CC(C)C[C@@H](C(=O)O)NC(=O)[C@H]([C@@H](CC1=CC=CC=C1)N)O	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BXO50L	(S,E)-5-(2-Chlorophenylamino)-4-(3-(3,4-dimethoxyphenyl)acrylamido)-5-oxopentanoic acid	Investigative	44582646	C22H23ClN2O6	446.9	COC1=C(C=C(C=C1)/C=C/C(=O)N[C@@H](CCC(=O)O)C(=O)NC2=CC=CC=C2Cl)OC	IC50 = 64300 nM	Poor binder
T68251	Matrix metalloproteinase-2	BXS80V	(2S)-2-Amino-N-[(2R)-1-[[(2S,3S)-2-amino-3-(4-aminophenyl)-3-hydroxypropyl]amino]-1-oxo-3-phenylpropan-2-yl]-4-methylpentanamide	Investigative	56672275	C24H35N5O3	441.6	CC(C)C[C@@H](C(=O)N[C@H](CC1=CC=CC=C1)C(=O)NC[C@@H]([C@H](C2=CC=C(C=C2)N)O)N)N	IC50 = 133800 nM	Poor binder
T68251	Matrix metalloproteinase-2	BXS9P4	4-Bromobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate	Investigative	44445226	C13H10BrNO3	308.13	C1=CC(=O)NC(=C1)C(=O)OCC2=CC=C(C=C2)Br	IC50 = 107000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BXUF15	(R)-2-(4-Fluorophenylsulphonamido-N-(pyridin-3-ylmethyl))-3-methylbutanoic acid	Investigative	23655714	C17H19FN2O4S	366.4	CC(C)[C@H](C(=O)O)N(CC1=CN=CC=C1)S(=O)(=O)C2=CC=C(C=C2)F	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BY0QU5	(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(methylsulfonyl)amino]-methyl}-1,2,4-oxadiazol-5-yl)hexanamide	Investigative	10271604	C16H28N4O5S	388.5	CS(=O)(=O)NCC1=NOC(=N1)[C@H](CCCC2CCCCC2)CC(=O)NO	Ki ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BY1Z5G	(R)-5-(2,4-Difluorophenylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid	Investigative	44582906	C21H22F2N2O7	452.4	COC1=CC(=CC(=C1OC)OC)C(=O)N[C@H](CCC(=O)O)C(=O)NC2=C(C=C(C=C2)F)F	IC50 = 108700 nM	Poor binder
T68251	Matrix metalloproteinase-2	BY23AO	N-[2-(4-Fluoro-phenyl)-ethyl]-2-[1-heptyl-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-acetamide	Investigative	44328259	C32H39FN4O5	578.7	CCCCCCCN(CC(=O)N(CCC1=CC=C(C=C1)F)CC(=O)NO)C(=O)NC2=CC=C(C=C2)OC3=CC=CC=C3	IC50 = 114000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BY2AJ0	(S)-2-(2-(3-((S)-2-Amino-3-phenylpropanamido)-2,6-dioxopiperidin-1-yl)acetamido)propanoic acid	Investigative	49863591	C19H24N4O6	404.4	C[C@@H](C(=O)O)NC(=O)CN1C(=O)CC[C@@H](C1=O)NC(=O)[C@H](CC2=CC=CC=C2)N	IC50 = 155000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BY2DQ0	N-Tert-Butyl-N-hydroxycarbamoylmethyl-2-[3-(2-methylsulfanyl-phenyl)-1-(3-phenyl-propyl)-ureido]-acetamide	Investigative	44328254	C25H34N4O4S	486.6	CC(C)(C)N(CC(=O)NO)C(=O)CN(CCCC1=CC=CC=C1)C(=O)NC2=CC=CC=C2SC	IC50 = 150000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BY8M6T	(2S)-N-(4-Fluorophenyl)-2-[[2-(3-methyl-2-oxoquinoxalin-1-yl)acetyl]amino]-3-phenylpropanamide	Investigative	46232363	C26H23FN4O3	458.5	CC1=NC2=CC=CC=C2N(C1=O)CC(=O)N[C@@H](CC3=CC=CC=C3)C(=O)NC4=CC=C(C=C4)F	IC50 = 124320 nM	Poor binder
T68251	Matrix metalloproteinase-2	BY97GQ	Ethyl 5-carbamoyl-1H-indole-2-carboxylate	Investigative	47162079	C12H12N2O3	232.23	CCOC(=O)C1=CC2=C(N1)C=CC(=C2)C(=O)N	IC50 = 60000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BYQI40	[Heptyl[1-(3-phenylpropyl)-3-(4-phenoxyphenyl)ureidoacetyl]amino]acetohydroximic acid	Investigative	44328168	C33H42N4O5	574.7	CCCCCCCN(CC(=O)NO)C(=O)CN(CCCC1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)OC3=CC=CC=C3	IC50 = 150000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BZ15OK	(R)-Ethyl 5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-1,2,4-oxadiazole-3-carboxylate	Investigative	10132758	C17H27N3O5	353.4	CCOC(=O)C1=NOC(=N1)[C@H](CCCC2CCCCC2)CC(=O)NO	IC50 = 80000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BZ7P0A	2-[1-[2-(4-Fluoro-phenyl)-ethyl]-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-N-isopropyl-acetamide	Investigative	44327476	C28H31FN4O5	522.6	CC(C)N(CC(=O)NO)C(=O)CN(CCC1=CC=C(C=C1)F)C(=O)NC2=CC=C(C=C2)OC3=CC=CC=C3	IC50 = 90000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BZ8IT5	2,4,5-Trifluorobenzyl 6-mercaptopicolinate	Investigative	44445258	C13H8F3NO2S	299.27	C1=CC(=S)NC(=C1)C(=O)OCC2=CC(=C(C=C2F)F)F	IC50 = 90000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BZ97RT	3-Phenylpropyl 6-mercaptopicolinate	Investigative	44445246	C15H15NO2S	273.4	C1=CC=C(C=C1)CCCOC(=O)C2=CC=CC(=S)N2	IC50 = 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	BZF41K	(2R)-2-Amino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]-3-sulfanylpropanamide	Investigative	56658262	C12H18N4O4S	314.36	C1=CC(=CC=C1[C@@H]([C@H](CNC(=O)[C@H](CS)N)N)O)[N+](=O)[O-]	IC50 = 151600 nM	Poor binder
T68251	Matrix metalloproteinase-2	BZK0R2	(2S)-2,6-Diamino-N-[(2S,3S)-2-amino-3-(4-aminophenyl)-3-hydroxypropyl]hexanamide	Investigative	56672134	C15H27N5O2	309.41	C1=CC(=CC=C1[C@@H]([C@H](CNC(=O)[C@H](CCCCN)N)N)O)N	IC50 = 157400 nM	Poor binder
T68251	Matrix metalloproteinase-2	BZSF06	N-{2-[(4'-Cyano-1,1'-biphenyl-4-YL)oxy]ethyl}-N'-hydroxy-N-methylurea	Investigative	5326979	C17H17N3O3	311.33	CN(CCOC1=CC=C(C=C1)C2=CC=C(C=C2)C#N)C(=O)NO	IC50 = 58000 nM	Poor binder
T68251	Matrix metalloproteinase-2	D00TRF	2-(benzyloxyamino)-N-hydroxyacetamide	Investigative	44423683	C9H12N2O3	196.2	C1=CC=C(C=C1)CONCC(=O)NO	IC50 = 94000 nM	Poor binder
T68251	Matrix metalloproteinase-2	D02ECA	PF-00356231	Investigative	448942	C25H20N2O3S	428.5	C1=CC=C(C=C1)[C@@H](CC(=O)O)NC(=O)C2=CC(=CS2)C3=CC=C(C=C3)C4=CC=NC=C4	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	D04GOO	N1,N3-bis(3-methoxybenzyl)isophthalamide	Investigative	10111838	C24H24N2O4	404.5	COC1=CC=CC(=C1)CNC(=O)C2=CC(=CC=C2)C(=O)NCC3=CC(=CC=C3)OC	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	D04PAW	Methotrexate gamma-L-phenylalaninehydroxamic acid	Investigative	16216218	C29H32N10O6	616.6	CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NO)C(=O)O	IC50 = 60000 nM	Poor binder
T68251	Matrix metalloproteinase-2	D05BMD	2-(4-chlorobenzyloxyamino)-N-hydroxyacetamide	Investigative	44423684	C9H11ClN2O3	230.65	C1=CC(=CC=C1CONCC(=O)NO)Cl	IC50 = 137000 nM	Poor binder
T68251	Matrix metalloproteinase-2	D06HSC	Folate gamma-L-phenylalaninehydroxamic acid	Investigative	136117931	C28H29N9O7	603.6	.	IC50 = 65000 nM	Poor binder
T68251	Matrix metalloproteinase-2	D06NDR	2-(4-chlorobenzyloxyamino)-N-hydroxyhexanamide	Investigative	44423687	C13H19ClN2O3	286.75	CCCCC(C(=O)NO)NOCC1=CC=C(C=C1)Cl	IC50 = 81800 nM	Poor binder
T68251	Matrix metalloproteinase-2	D07VXX	2-(benzyloxyamino)-N-hydroxy-3-methylpentanamide	Investigative	16721024	C13H20N2O3	252.31	CCC(C)C(C(=O)NO)NOCC1=CC=CC=C1	IC50 = 151000 nM	Poor binder
T68251	Matrix metalloproteinase-2	D09GIL	5-Methyl-5-phenyl-pyrimidine-2,4,6-trione	Investigative	66160	C11H10N2O3	218.21	CC1(C(=O)NC(=O)NC1=O)C2=CC=CC=C2	IC50 = 50000 nM	Poor binder
T68251	Matrix metalloproteinase-2	D09USO	(biphenyl-3-ylamino)methylenediphosphonic acid	Investigative	5277466	C13H15NO6P2	343.21	C1=CC=C(C=C1)C2=CC(=CC=C2)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T68251	Matrix metalloproteinase-2	D0D7GL	TROPOLONE	Investigative	10789	C7H6O2	122.12	C1=CC=C(C(=O)C=C1)O	IC50 = 146000 nM	Poor binder
T68251	Matrix metalloproteinase-2	D0F2HJ	2-Cinnamamido-N1-hydroxy-N4-pentylsuccinamide	Investigative	45257111	C18H25N3O4	347.4	CCCCCNC(=O)C[C@H](C(=O)NO)NC(=O)/C=C/C1=CC=CC=C1	IC50 = 196500 nM	Poor binder
T68251	Matrix metalloproteinase-2	D0FO2B	OXYQUINOLINE	Investigative	1923	C9H7NO	145.16	C1=CC2=C(C(=C1)O)N=CC=C2	IC50 = 130000 nM	Poor binder
T68251	Matrix metalloproteinase-2	D0G0OP	2-(4-chlorobenzyloxyamino)-N-hydroxypropanamide	Investigative	44423685	C10H13ClN2O3	244.67	CC(C(=O)NO)NOCC1=CC=C(C=C1)Cl	IC50 = 68000 nM	Poor binder
T68251	Matrix metalloproteinase-2	D0P2TS	UK-383367	Investigative	9818682	C15H24N4O4	324.38	C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C(=O)N	IC50 ~ 60000 nM	Poor binder
T68251	Matrix metalloproteinase-2	D0UI1P	2-Cinnamamido-N4-hexyl-N1-hydroxysuccinamide	Investigative	46228278	C19H27N3O4	361.4	CCCCCCNC(=O)C[C@H](C(=O)NO)NC(=O)/C=C/C1=CC=CC=C1	IC50 = 178600 nM	Poor binder