TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T69375	Stress-activated protein kinase JNK2	B0BQ9J	3-(Pyridin-4-yl)-4-(quinolin-6-yl)-1H-1,2,4-triazole-5(4H)-thione	Investigative	942437	C16H11N5S	305.4	C1=CC2=C(C=CC(=C2)N3C(=NNC3=S)C4=CC=NC=C4)N=C1	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	B19QVJ	4-(5-(Naphthalen-2-yl)-1H-tetrazol-1-yl)pyridine	Investigative	54581363	C16H11N5	273.29	C1=CC=C2C=C(C=CC2=C1)C3=NN=NN3C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	B2QYF7	Methyl 5-(2-(naphthalen-1-yl)acetamido)-1,2,3-thiadiazole-4-carboxylate	Investigative	52947399	C16H13N3O3S	327.4	COC(=O)C1=C(SN=N1)NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	B2YR0X	3-(2-Phenylacetamido)thiophene-2-carboxamide	Investigative	52943431	C13H12N2O2S	260.31	C1=CC=C(C=C1)CC(=O)NC2=C(SC=C2)C(=O)N	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	B37XDZ	N-(2-(1-Methyl-1H-pyrazol-3-yl)thiophen-3-yl)-2-(naphthalen-1-yl)acetamide	Investigative	46869147	C20H17N3OS	347.4	CN1C=CC(=N1)C2=C(C=CS2)NC(=O)CC3=CC=CC4=CC=CC=C43	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	B3UI9B	1-(2-Hydroxy-2-methylpropyl)-N-(5-((7-methoxyquinolin-4-yl)oxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide	Investigative	24764449	C30H29N5O5	539.6	CC1=C(C(=O)N(N1CC(C)(C)O)C2=CC=CC=C2)C(=O)NC3=NC=C(C=C3)OC4=C5C=CC(=CC5=NC=C4)OC	IC50 = 100000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	B4TK6V	N-(4-Methylpyridin-3-yl)-2-(naphthalen-1-yl)acetamide	Investigative	52944962	C18H16N2O	276.3	CC1=C(C=NC=C1)NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	B4ZA2H	3-(2-Methylpyridin-4-yl)-4-(quinolin-3-yl)-1H-1,2,4-triazole-5(4H)-thione	Investigative	54585286	C17H13N5S	319.4	CC1=NC=CC(=C1)C2=NNC(=S)N2C3=CC4=CC=CC=C4N=C3	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	B5EFI6	3-((3-Bromo-4-(2,4-difluorobenzyloxy)-6-methyl-2-oxopyridin-1(2H)-yl)methyl)benzamide	Investigative	11431185	C21H17BrF2N2O3	463.3	CC1=CC(=C(C(=O)N1CC2=CC(=CC=C2)C(=O)N)Br)OCC3=C(C=C(C=C3)F)F	IC50 = 167000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	B69XRH	Methyl 4-(2-(naphthalen-1-yl)acetamido)thiazole-5-carboxylate	Investigative	52947421	C17H14N2O3S	326.4	COC(=O)C1=C(N=CS1)NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	B6TY8C	5-[3-Fluoro-4-[[6-methoxy-7-(3-morpholinopropoxy)quinolin-4-yl]oxy]phenyl]-2-(4-fluorophenylamino)-3-methylpyrimidin-4(3H)-one	Investigative	11858109	C34H33F2N5O5	629.7	CN1C(=O)C(=CN=C1NC2=CC=C(C=C2)F)C3=CC(=C(C=C3)OC4=C5C=C(C(=CC5=NC=C4)OCCCN6CCOCC6)OC)F	IC50 ~ 100000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	B7O8WI	Ethyl 3-methyl-5-(2-(naphthalen-1-yl)acetamido)isothiazole-4-carboxylate	Investigative	52946172	C19H18N2O3S	354.4	CCOC(=O)C1=C(SN=C1C)NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BAH08N	Methyl 3-(2-(pyridin-4-yl)acetamido)thiophene-2-carboxylate	Investigative	43623574	C13H12N2O3S	276.31	COC(=O)C1=C(C=CS1)NC(=O)CC2=CC=NC=C2	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BAOC68	N-(2-(1H-1,2,4-Triazol-1-yl)thiophen-3-yl)-2-(4-methoxyphenyl)acetamide	Investigative	46869671	C15H14N4O2S	314.4	COC1=CC=C(C=C1)CC(=O)NC2=C(SC=C2)N3C=NC=N3	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BCZ2E3	3-(Pyridin-4-yl)-4-(quinolin-3-yl)-1H-1,2,4-triazole-5(4H)-thione	Investigative	54581359	C16H11N5S	305.4	C1=CC=C2C(=C1)C=C(C=N2)N3C(=NNC3=S)C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BD3C7X	N-(3-Methylpyrazin-2-yl)-2-(naphthalen-1-yl)acetamide	Investigative	52949737	C17H15N3O	277.32	CC1=NC=CN=C1NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BF3T7C	4-(5-Chloro-4-(naphthalen-2-yl)-4H-1,2,4-triazol-3-yl)pyridine	Investigative	54584316	C17H11ClN4	306.7	C1=CC=C2C=C(C=CC2=C1)N3C(=NN=C3Cl)C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BG7SD0	Methyl 3-(2-(4-(pyridin-4-yl)phenyl)acetamido)thiophene-2-carboxylate	Investigative	52950113	C19H16N2O3S	352.4	COC(=O)C1=C(C=CS1)NC(=O)CC2=CC=C(C=C2)C3=CC=NC=C3	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BGT1I7	Ethyl 2-(2-(4-methoxyphenyl)acetamido)-4-(trifluoromethyl)thiophene-3-carboxylate	Investigative	53317337	C17H16F3NO4S	387.4	CCOC(=O)C1=C(SC=C1C(F)(F)F)NC(=O)CC2=CC=C(C=C2)OC	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BHGF89	N-(2-Acetylthiophen-3-yl)-2-phenylacetamide	Investigative	52941649	C14H13NO2S	259.329	CC(=O)C1=C(C=CS1)NC(=O)CC2=CC=CC=C2	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BHNV01	4-(3-(6-(2,4-Difluorophenylamino)-1H-pyrazolo[3,4-b]pyrazin-3-yl)-4-methoxyphenyl)-2-methylbut-3-yn-2-ol	Investigative	11697791	C23H19F2N5O2	435.4	CC(C)(C#CC1=CC(=C(C=C1)OC)C2=C3C(=NN2)N=C(C=N3)NC4=C(C=C(C=C4)F)F)O	IC50 ~ 100000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BHO37A	Methyl 3-(2-(naphthalen-2-yl)acetamido)thiophene-2-carboxylate	Investigative	26704995	C18H15NO3S	325.4	COC(=O)C1=C(C=CS1)NC(=O)CC2=CC3=CC=CC=C3C=C2	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BI91UH	4-(4-(Naphthalen-2-yl)-5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl)pyridine	Investigative	54585289	C18H11F3N4	340.3	C1=CC=C2C=C(C=CC2=C1)N3C(=NN=C3C(F)(F)F)C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BIKL82	3-(5-(3-Amino-3-methylbut-1-ynyl)-2-methoxyphenyl)-N-(2,4-difluorophenyl)-1H-pyrazolo[3,4-b]pyridin-6-amine	Investigative	11568224	C24H21F2N5O	433.5	CC(C)(C#CC1=CC(=C(C=C1)OC)C2=C3C=CC(=NC3=NN2)NC4=C(C=C(C=C4)F)F)N	IC50 = 100000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BJ5BU1	N-(2-(1H-Pyrazol-3-yl)thiophen-3-yl)-2-(naphthalen-1-yl)acetamide	Investigative	46869075	C19H15N3OS	333.4	C1=CC=C2C(=C1)C=CC=C2CC(=O)NC3=C(SC=C3)C4=CC=NN4	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BK0SI2	Methyl 3-(2-(4-(1H-imidazol-1-yl)phenyl)acetamido)thiophene-2-carboxylate	Investigative	52944914	C17H15N3O3S	341.4	COC(=O)C1=C(C=CS1)NC(=O)CC2=CC=C(C=C2)N3C=CN=C3	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BMDO73	4-(1-(Naphthalen-2-yl)-1H-tetrazol-5-yl)pyridine	Investigative	54586233	C16H11N5	273.29	C1=CC=C2C=C(C=CC2=C1)N3C(=NN=N3)C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BNV7D1	3-Bromo-4-(2,4-difluorobenzyloxy)-1-(4-((dimethylamino)methyl)benzyl)-6-methylpyridin-2(1H)-one	Investigative	22050722	C23H23BrF2N2O2	477.3	CC1=CC(=C(C(=O)N1CC2=CC=C(C=C2)CN(C)C)Br)OCC3=C(C=C(C=C3)F)F	IC50 ~ 171000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BP3CX9	Methyl 2-(2-(naphthalen-1-yl)acetamido)nicotinate	Investigative	52947422	C19H16N2O3	320.3	COC(=O)C1=C(N=CC=C1)NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BQCP72	Methyl 3-(2-(4-(trifluoromethyl)phenyl)acetamido)thiophene-2-carboxylate	Investigative	24535122	C15H12F3NO3S	343.3	COC(=O)C1=C(C=CS1)NC(=O)CC2=CC=C(C=C2)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BR4Y0D	N-[2-(2,5-Dimethyl-1,2,4-triazol-3-yl)thiophen-3-yl]-2-naphthalen-1-ylacetamide	Investigative	46869609	C20H18N4OS	362.4	CC1=NN(C(=N1)C2=C(C=CS2)NC(=O)CC3=CC=CC4=CC=CC=C43)C	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BRDF65	Methyl 4-(2-(naphthalen-1-yl)acetamido)-1,2,5-oxadiazole-3-carboxylate	Investigative	52942532	C16H13N3O4	311.29	COC(=O)C1=NON=C1NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BT0C4K	2-(4-Methoxyphenyl)-N-(2-(2-methyl-1H-imidazol-4-yl)thiophen-3-yl)acetamide	Investigative	52946092	C17H17N3O2S	327.4	CC1=NC=C(N1)C2=C(C=CS2)NC(=O)CC3=CC=C(C=C3)OC	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BU4G7R	4-(4-(4-Fluorophenyl)-2-(4-methylcyclohexyl)-1H-imidazol-5-yl)pyridine	Investigative	44576212	C21H22FN3	335.4	CC1CCC(CC1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F	IC50 = 166000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BVA86K	N-(2-Methoxyethyl)-3-(2-phenylacetamido)thiophene-2-carboxamide	Investigative	52947386	C16H18N2O3S	318.4	COCCNC(=O)C1=C(C=CS1)NC(=O)CC2=CC=CC=C2	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BW8YL0	N-{4-[(6,7-Dimethoxyquinolin-4-Yl)oxy]-3-Fluorophenyl}-1,5-Dimethyl-3-Oxo-2-Phenyl-2,3-Dihydro-1h-Pyrazole-4-Carboxamide	Investigative	56604907	C29H25FN4O5	528.5	CC1=C(C(=O)N(N1C)C2=CC=CC=C2)C(=O)NC3=CC(=C(C=C3)OC4=C5C=C(C(=CC5=NC=C4)OC)OC)F	IC50 = 100000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BWXT95	2-(4-Methoxyphenyl)-N-(2-(2-oxooxazolidin-3-yl)thiophen-3-yl)acetamide	Investigative	52942482	C16H16N2O4S	332.4	COC1=CC=C(C=C1)CC(=O)NC2=C(SC=C2)N3CCOC3=O	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BX2NC6	N-(2-(1H-Imidazol-1-yl)thiophen-3-yl)-2-(naphthalen-1-yl)acetamide	Investigative	52946059	C19H15N3OS	333.4	C1=CC=C2C(=C1)C=CC=C2CC(=O)NC3=C(SC=C3)N4C=CN=C4	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BX68VA	N-(2-Methoxyethyl)-N-methyl-3-(2-phenylacetamido)thiophene-2-carboxamide	Investigative	52948602	C17H20N2O3S	332.4	CN(CCOC)C(=O)C1=C(C=CS1)NC(=O)CC2=CC=CC=C2	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BY0TR9	2-(4-Methoxyphenyl)-N-(2-(1-methyl-1H-imidazol-4-yl)thiophen-3-yl)acetamide	Investigative	52948565	C17H17N3O2S	327.4	CN1C=C(N=C1)C2=C(C=CS2)NC(=O)CC3=CC=C(C=C3)OC	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	BZ21PQ	3-(2-Bromopyridin-4-yl)-4-(naphthalen-2-yl)-1H-1,2,4-triazole-5(4H)-thione	Investigative	54585287	C17H11BrN4S	383.3	C1=CC=C2C=C(C=CC2=C1)N3C(=NNC3=S)C4=CC(=NC=C4)Br	IC50 ~ 50000 nM	Poor binder
T69375	Stress-activated protein kinase JNK2	D07OXC	AM7	Investigative	11650194	C35H35FN4O5	610.7	CN1C(=NC=C(C1=O)C2=CC(=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OCCCN5CCOCC5)OC)F)CC6=CC=CC=C6	IC50 ~ 100000 nM	Poor binder