TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T71390	Steroid 5-alpha-reductase 2	B7NJM2	(2R,3As,5aS,11aS)-3a,5a,6-trimethyl-7-oxo-N,N-di(propan-2-yl)-2,3,3b,4,5,8,9,9a,9b,10,11,11a-dodecahydro-1H-indeno[5,4-f]quinoline-2-carboxamide	Investigative	44381333	C26H44N2O2	416.6	CC(C)N(C(C)C)C(=O)[C@@H]1C[C@@H]2CCC3C4CCC(=O)N([C@]4(CCC3[C@]2(C1)C)C)C	IC50 ~ 100000 nM	Poor binder
T71390	Steroid 5-alpha-reductase 2	BBN3Y4	3beta-Hydroxy-21-(1H-imidazole-1-yl)pregna-5,16-diene-20-one	Investigative	132531900	C24H32N2O2	380.5	C[C@]12CC[C@@H](CC1=CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC=C4C(=O)CN5C=CN=C5)C)O	IC50 = 118800 nM	Poor binder
T71390	Steroid 5-alpha-reductase 2	BM0QF7	4-[2-[5-(Benzhydrylcarbamoyl)benzofuran-2-yl]phenoxy]butanoic Acid	Investigative	10006358	C32H27NO5	505.6	C1=CC=C(C=C1)C(C2=CC=CC=C2)NC(=O)C3=CC4=C(C=C3)OC(=C4)C5=CC=CC=C5OCCCC(=O)O	IC50 ~ 100000 nM	Poor binder
T71390	Steroid 5-alpha-reductase 2	BO05KN	[(3S,8R,9S,10R,13S,14S)-10,13-Dimethyl-17-[2-(1,2,4-triazol-1-yl)acetyl]-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate	Investigative	127034703	C25H33N3O3	423.5	CC(=O)O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1)CC=C4C(=O)CN5C=NC=N5)C)C	IC50 = 100000 nM	Poor binder
T71390	Steroid 5-alpha-reductase 2	BOQE07	[(3S,8R,9S,10R,13S,14S)-17-(2-Imidazol-1-ylacetyl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate	Investigative	137631999	C26H34N2O3	422.6	CC(=O)O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1)CC=C4C(=O)CN5C=CN=C5)C)C	IC50 = 122000 nM	Poor binder
T71390	Steroid 5-alpha-reductase 2	BQSG96	[(3S,8R,9S,10R,13S,14S)-10,13-Dimethyl-17-[2-(1,2,4-triazol-1-yl)acetyl]-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl] cyclopropanecarboxylate	Investigative	127035071	C27H35N3O3	449.6	C[C@]12CC[C@@H](CC1=CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC=C4C(=O)CN5C=NC=N5)C)OC(=O)C6CC6	IC50 = 118000 nM	Poor binder
T71390	Steroid 5-alpha-reductase 2	BW80AY	19-Nor-10-aza-5alpha-androstane-3,17-dione	Investigative	10850018	C17H25NO2	275.4	C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC[C@@H]4N3CCC(=O)C4	IC50 ~ 100000 nM	Poor binder