TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T72335	Bacterial Lethal factor	B0K3CW	N-(3-Chloro-4-methylphenyl)thiophene-2-sulfonamide	Investigative	2275298	C11H10ClNO2S2	287.8	CC1=C(C=C(C=C1)NS(=O)(=O)C2=CC=CS2)Cl	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B0ZK4Y	2-(4-Methoxyphenyl)-6-(4,5-dihydro-1H-imidazol-2-yl)-1Hindole	Investigative	46228784	C24H21N3O2	383.4	COC1=CC=C(C=C1)OC2=CC=C(C=C2)C3=CC4=C(N3)C=C(C=C4)C5=NCCN5	IC50 = 61000 nM	Poor binder
T72335	Bacterial Lethal factor	B13IXO	N1-(6-(6-(4,5-Dihydro-1H-imidazol-2-yl)benzo[b]thiophen-2-yl)-pyridine-3-yl)ethane-1,2-diamine	Investigative	46228837	C24H23N5OS	429.5	C1CN=C(N1)C2=CC3=C(C=C2)N=C(S3)C4=CC=C(C=C4)OC5=CC=C(C=C5)NCCN	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B19GHB	N-(4-Amino-2-methylquinolin-6-yl)-3-(2,3-dimethoxyphenyl)propanamide	Investigative	73055302	C21H23N3O3	365.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCC3=C(C(=CC=C3)OC)OC)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B19KXQ	(E)-2-(1H-Benzimidazol-2-yl)-3-[5-(furan-2-yl)thiophen-2-yl]prop-2-enenitrile	Investigative	50943152	C18H11N3OS	317.4	C1=CC=C2C(=C1)NC(=N2)/C(=C/C3=CC=C(S3)C4=CC=CO4)/C#N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B1B2ZH	6-(1,4,5,6-Tetrahydropyrimidin-2-yl)-2-[4-(1,4,5,6-tetrahydropyrimidin-2-yl)phenyl]-1H-indole	Investigative	45139819	C22H23N5	357.5	C1CNC(=NC1)C2=CC=C(C=C2)C3=CC4=C(N3)C=C(C=C4)C5=NCCCN5	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B1C3NQ	2-(5-(4-Cyanophenoxy)pyridin-2-yl)-1H-indole-6-carbonitrile	Investigative	45139447	C21H12N4O	336.3	C1=CC(=CC=C1C#N)OC2=CN=C(C=C2)C3=CC4=C(N3)C=C(C=C4)C#N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B1G2NA	6-(1,4,5,6-Tetrahydropyrimidin-2-yl)-2-[5-[4-(1,4,5,6-tetrahydropyrimidin-2-yl)phenoxy]pyridin-2-yl]-1H-indole	Investigative	45139630	C27H26N6O	450.5	C1CNC(=NC1)C2=CC=C(C=C2)OC3=CN=C(C=C3)C4=CC5=C(N4)C=C(C=C5)C6=NCCCN6	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B1GH3Z	N-(4-Amino-2-methylquinolin-6-yl)-3-(3-methoxyphenyl)propanamide	Investigative	73055300	C20H21N3O2	335.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCC3=CC(=CC=C3)OC)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B23FXK	4-Chloro-3-[5-[(E)-2-cyano-3-morpholin-4-yl-3-oxoprop-1-enyl]furan-2-yl]benzoic acid	Investigative	1270226	C19H15ClN2O5	386.8	C1COCCN1C(=O)/C(=C/C2=CC=C(O2)C3=C(C=CC(=C3)C(=O)O)Cl)/C#N	IC50 = 50000 nM	Poor binder
T72335	Bacterial Lethal factor	B24FNP	(2R)-2-[3-Acetamidopropyl-(4-fluoro-3-methylphenyl)sulfonylamino]-N-hydroxypropanamide	Investigative	122196506	C15H22FN3O5S	375.4	CC1=C(C=CC(=C1)S(=O)(=O)N(CCCNC(=O)C)[C@H](C)C(=O)NO)F	IC50 = 117000 nM	Poor binder
T72335	Bacterial Lethal factor	B2V9KD	N-(4-Amino-2-methylquinolin-6-yl)isoquinoline-3-carboxamide	Investigative	73054731	C20H16N4O	328.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC4=CC=CC=C4C=N3)N	IC50 = 52000 nM	Poor binder
T72335	Bacterial Lethal factor	B38PGZ	(2R)-2-[(4-Fluoro-3-methylphenyl)sulfonyl-(2-phenylmethoxyethyl)amino]-N-hydroxypropanamide	Investigative	122196483	C19H23FN2O5S	410.5	CC1=C(C=CC(=C1)S(=O)(=O)N(CCOCC2=CC=CC=C2)[C@H](C)C(=O)NO)F	IC50 = 57000 nM	Poor binder
T72335	Bacterial Lethal factor	B3B9ZX	(2E)-2-(1H-Benzimidazol-2-yl)-3-(3-bromo-4-methoxyphenyl)prop-2-enenitrile	Investigative	5931873	C17H12BrN3O	354.2	COC1=C(C=C(C=C1)/C=C(\\C#N)/C2=NC3=CC=CC=C3N2)Br	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B3X1LZ	N-(2-Methoxyethyl)-5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine	Investigative	46232269	C8H9N5O3S3	319.4	COCCNC1=NN=C(S1)SC2=NC=C(S2)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B46LMV	N-(3-(Benzo[d]thiazol-2-yl)-4-methylthiophen-2-yl)-3-chloro-4-fluorobenzenesulfonamide	Investigative	45269696	C18H12ClFN2O2S3	439	CC1=CSC(=C1C2=NC3=CC=CC=C3S2)NS(=O)(=O)C4=CC(=C(C=C4)F)Cl	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B49QTX	3-Chloro-4-methyl-N-(thiophen-2-yl)benzenesulfonamide	Investigative	45268002	C11H10ClNO2S2	287.8	CC1=C(C=C(C=C1)S(=O)(=O)NC2=CC=CS2)Cl	IC50 ~ 50000 nM	Poor binder
T72335	Bacterial Lethal factor	B4K5YS	(E)-2-(1H-Benzimidazol-2-yl)-3-(3,4-dimethoxyphenyl)prop-2-enenitrile	Investigative	5289928	C18H15N3O2	305.3	COC1=C(C=C(C=C1)/C=C(\\C#N)/C2=NC3=CC=CC=C3N2)OC	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B4P6MD	N-(Benzo[d]thiazol-2-yl)-4''-chlorobiphenyl-4-sulfonamide	Investigative	45273114	C19H13ClN2O2S2	400.9	C1=CC=C2C(=C1)N=C(S2)NS(=O)(=O)C3=CC=C(C=C3)C4=CC=C(C=C4)Cl	IC50 ~ 50000 nM	Poor binder
T72335	Bacterial Lethal factor	B4P9TV	N-(3,4-Dimethoxyphenethyl)-5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine	Investigative	46232270	C15H15N5O4S3	425.5	COC1=C(C=C(C=C1)CCNC2=NN=C(S2)SC3=NC=C(S3)[N+](=O)[O-])OC	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B4V5HK	N-(4-Amino-2-methylquinolin-6-yl)-3-(5-chloro-2-methoxyphenyl)propanamide	Investigative	73056474	C20H20ClN3O2	369.8	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCC3=C(C=CC(=C3)Cl)OC)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B4VJ1M	4''-Methoxy-N-(thiophen-2-yl)biphenyl-4-sulfonamide	Investigative	45269722	C17H15NO3S2	345.4	COC1=CC=C(C=C1)C2=CC=C(C=C2)S(=O)(=O)NC3=CC=CS3	IC50 ~ 50000 nM	Poor binder
T72335	Bacterial Lethal factor	B51CVO	2-(4-(2,4-Dichlorophenoxy)phenyl)-6-(4,5-dihydro-1H-imidazol-2-yl)-1H-indole	Investigative	45142028	C23H17Cl2N3O	422.3	C1CN=C(N1)C2=CC3=C(C=C2)C=C(N3)C4=CC=C(C=C4)OC5=C(C=C(C=C5)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B5A3TX	N-[3-(1,3-Benzothiazol-2-yl)-3a,4,5,6,7,7a-hexahydro-1-benzothiophen-2-yl]-4-(4-chlorophenyl)benzenesulfonamide	Investigative	45269714	C27H23ClN2O2S3	539.1	C1CCC2C(C1)C(=C(S2)NS(=O)(=O)C3=CC=C(C=C3)C4=CC=C(C=C4)Cl)C5=NC6=CC=CC=C6S5	IC50 ~ 50000 nM	Poor binder
T72335	Bacterial Lethal factor	B5FMI2	N-(4-Amino-2-methylquinolin-6-yl)-2-(2-chlorophenyl)acetamide	Investigative	73056771	C18H16ClN3O	325.8	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CC3=CC=CC=C3Cl)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B5OC0L	CID 50943150	Investigative	50943150	C18H11N3S2	333.4	C1=CC=C2C(=C1)NC(=N2)/C(=C/C3=CC=C(S3)C4=CC=CS4)/C#N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B5S3EG	2-[(5Z)-4-Oxo-2-sulfanylidene-5-(1,3-thiazol-2-ylmethylidene)-1,3-thiazolidin-3-yl]acetic acid	Investigative	6539638	C9H6N2O3S3	286.4	C1=CSC(=N1)/C=C\\2/C(=O)N(C(=S)S2)CC(=O)O	IC50 = 72400 nM	Poor binder
T72335	Bacterial Lethal factor	B5V2QM	N-(4-Amino-2-methylquinolin-6-yl)-3-(5-bromo-2-methoxyphenyl)propanamide	Investigative	73056473	C20H20BrN3O2	414.3	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCC3=C(C=CC(=C3)Br)OC)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B5Z6WJ	N-(4-Amino-2-methylquinolin-6-yl)-3-(4-methoxyphenyl)propanamide	Investigative	73055019	C20H21N3O2	335.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCC3=CC=C(C=C3)OC)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B65IAM	2-(4-(4-Carbamoylphenoxy)phenyl)-1H-indole-6-carboxamide	Investigative	45141625	C22H17N3O3	371.4	C1=CC(=CC=C1C2=CC3=C(N2)C=C(C=C3)C(=O)N)OC4=CC=C(C=C4)C(=O)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B6FU3L	1-(4-Amino-2-methylquinolin-6-yl)-3-[(2-chlorophenyl)methyl]urea	Investigative	73055606	C18H17ClN4O	340.8	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)NCC3=CC=CC=C3Cl)N	IC50 = 61000 nM	Poor binder
T72335	Bacterial Lethal factor	B6JWI3	N-(4-Amino-2-methyl-6-quinolinyl)-3-phenylpropanamide	Investigative	15133398	C19H19N3O	305.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCC3=CC=CC=C3)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B6K2ID	N-(4-Amino-2-methylquinolin-6-yl)-3-(2-methylphenyl)propanamide	Investigative	73056182	C20H21N3O	319.4	CC1=CC=CC=C1CCC(=O)NC2=CC3=C(C=C(N=C3C=C2)C)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B6MH5S	N-(4-Amino-2-methylquinolin-6-yl)-3-(2-chlorophenyl)propanamide	Investigative	73055304	C19H18ClN3O	339.8	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCC3=CC=CC=C3Cl)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B6Y9JP	N-(3-(Benzo[d]thiazol-2-yl)-4-methylthiophen-2-yl)-3-chlorobenzenesulfonamide	Investigative	45269708	C18H13ClN2O2S3	421	CC1=CSC(=C1C2=NC3=CC=CC=C3S2)NS(=O)(=O)C4=CC(=CC=C4)Cl	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B75KHY	N-(3-(Benzo[d]thiazol-2-yl)-4-methylthiophen-2-yl)-4-fluoro-N-(4-fluorophenylsulfonyl)benzenesulfonamide	Investigative	45269729	C24H16F2N2O4S4	562.7	CC1=CSC(=C1C2=NC3=CC=CC=C3S2)N(S(=O)(=O)C4=CC=C(C=C4)F)S(=O)(=O)C5=CC=C(C=C5)F	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B7A5QS	(E)-2-(1H-Benzimidazol-2-yl)-3-(3-chloro-4-methoxyphenyl)prop-2-enenitrile	Investigative	5765823	C17H12ClN3O	309.7	COC1=C(C=C(C=C1)/C=C(\\C#N)/C2=NC3=CC=CC=C3N2)Cl	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B7A6WM	1-(4-Amino-2-methylquinolin-6-yl)-3-(4-propan-2-ylphenyl)urea	Investigative	73055604	C20H22N4O	334.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)NC3=CC=C(C=C3)C(C)C)N	IC50 = 83000 nM	Poor binder
T72335	Bacterial Lethal factor	B7GVJ1	5-(5-Nitrothiazol-2-ylthio)-N-propyl-1,3,4-thiadiazol-2-amine	Investigative	46232267	C8H9N5O2S3	303.4	CCCNC1=NN=C(S1)SC2=NC=C(S2)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B7MQ1G	6-(4,5-Dihydro-1H-imidazol-2-yl)-2-[5-[4-(4,5-dihydro-1H-imidazol-2-yl)phenoxy]pyridin-2-yl]-1H-indole	Investigative	45139450	C25H22N6O	422.5	C1CN=C(N1)C2=CC=C(C=C2)OC3=CN=C(C=C3)C4=CC5=C(N4)C=C(C=C5)C6=NCCN6	IC50 = 55000 nM	Poor binder
T72335	Bacterial Lethal factor	B7P0DT	N-Phenylthiophene-2-sulfonamide	Investigative	769062	C10H9NO2S2	239.3	C1=CC=C(C=C1)NS(=O)(=O)C2=CC=CS2	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B80XLB	(E)-2-(1H-Benzimidazol-2-yl)-3-(1H-benzo[g]indol-3-yl)prop-2-enenitrile	Investigative	136042249	C22H14N4	334.4	C1=CC=C2C(=C1)C=CC3=C2NC=C3/C=C(\\C#N)/C4=NC5=CC=CC=C5N4	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B85AIS	(E)-2-(1H-Benzimidazol-2-yl)-3-(4,6-dichloropyrimidin-5-yl)prop-2-enenitrile	Investigative	57393300	C14H7Cl2N5	316.1	C1=CC=C2C(=C1)NC(=N2)/C(=C/C3=C(N=CN=C3Cl)Cl)/C#N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B8LDS4	2-(1H-Benzimidazol-2-yl)-3-(3-chloro-4-hydroxy-5-methoxyphenyl)acrylonitrile	Investigative	135457658	C17H12ClN3O2	325.7	COC1=C(C(=CC(=C1)/C=C(\\C#N)/C2=NC3=CC=CC=C3N2)Cl)O	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B8TAW3	N-(4-Amino-2-methylquinolin-6-yl)-4-(2-methoxyphenyl)butanamide	Investigative	73056772	C21H23N3O2	349.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCCC3=CC=CC=C3OC)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B8Y2HA	(Z)-2-Quinolin-2-yl-3-(5-thiophen-2-ylthiophen-2-yl)prop-2-enenitrile	Investigative	57398522	C20H12N2S2	344.5	C1=CC=C2C(=C1)C=CC(=N2)/C(=C/C3=CC=C(S3)C4=CC=CS4)/C#N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	B9N4CL	N-(2-(Benzo[d]thiazol-2-yl)ethyll)-4''-methoxybiphenyl-4-sulfonamide	Investigative	45267993	C22H20N2O3S2	424.5	COC1=CC=C(C=C1)C2=CC=C(C=C2)S(=O)(=O)NCCC3=NC4=CC=CC=C4S3	IC50 ~ 50000 nM	Poor binder
T72335	Bacterial Lethal factor	B9WM0X	N-(4-Amino-2-methylquinolin-6-yl)quinoline-2-carboxamide	Investigative	73054732	C20H16N4O	328.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=NC4=CC=CC=C4C=C3)N	IC50 = 81000 nM	Poor binder
T72335	Bacterial Lethal factor	BARP76	N-(3-(Benzo[d]thiazol-2-yl)-4-methylthiophen-2-yl)-4-methylbenzenesulfonamide	Investigative	45272242	C19H16N2O2S3	400.5	CC1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=CS2)C)C3=NC4=CC=CC=C4S3	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BBJI57	(E)-N-(4-Amino-2-methylquinolin-6-yl)-3-(4-methoxyphenyl)prop-2-enamide	Investigative	73055015	C20H19N3O2	333.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)/C=C/C3=CC=C(C=C3)OC)N	IC50 = 55000 nM	Poor binder
T72335	Bacterial Lethal factor	BBQ1P7	2-[4-(4-Fluorophenoxy)phenyl]-1H-indole-6-carbonitrile	Investigative	46228743	C21H13FN2O	328.3	C1=CC(=CC=C1C2=CC3=C(N2)C=C(C=C3)C#N)OC4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BBW67Q	(2E)-2-(1H-Benzimidazol-2-yl)-3-(3-iodophenyl)prop-2-enenitrile	Investigative	5738908	C16H10IN3	371.17	C1=CC=C2C(=C1)NC(=N2)/C(=C/C3=CC(=CC=C3)I)/C#N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BBX01M	N-(3-(Benzo[d]thiazol-2-yl)-4-methylthiophen-2-yl)benzenesulfonamide	Investigative	45271340	C18H14N2O2S3	386.5	CC1=CSC(=C1C2=NC3=CC=CC=C3S2)NS(=O)(=O)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BC2A5N	N-(4-Amino-2-methylquinolin-6-yl)-3-(2-propoxyphenyl)propanamide	Investigative	73056478	C22H25N3O2	363.5	CCCOC1=CC=CC=C1CCC(=O)NC2=CC3=C(C=C(N=C3C=C2)C)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BCS8B5	(5E)-5-[[5-[2-Chloro-5-(trifluoromethyl)phenyl]furan-2-yl]methylidene]-2-imino-1-methylimidazolidin-4-one	Investigative	137629906	C16H11ClF3N3O2	369.72	CN1/C(=C/C2=CC=C(O2)C3=C(C=CC(=C3)C(F)(F)F)Cl)/C(=O)NC1=N	IC50 = 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BD5JT4	(E)-2-(1H-Benzimidazol-2-yl)-3-(2-chloro-5-phenylpyridin-3-yl)prop-2-enenitrile	Investigative	57393299	C21H13ClN4	356.8	C1=CC=C(C=C1)C2=CC(=C(N=C2)Cl)/C=C(\\C#N)/C3=NC4=CC=CC=C4N3	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BD8F6A	(E)-2-(1H-Benzimidazol-2-yl)-3-[4-(3-bromo-4-hydroxy-5-methoxyphenyl)phenyl]prop-2-enenitrile	Investigative	136042247	C23H16BrN3O2	446.3	COC1=C(C(=CC(=C1)C2=CC=C(C=C2)/C=C(\\C#N)/C3=NC4=CC=CC=C4N3)Br)O	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BDL6H9	N-[3-(1,3-Benzothiazol-2-yl)-3a,4,5,6,7,7a-hexahydro-1-benzothiophen-2-yl]-4-(4-methoxyphenyl)benzenesulfonamide	Investigative	45271365	C28H26N2O3S3	534.7	COC1=CC=C(C=C1)C2=CC=C(C=C2)S(=O)(=O)NC3=C(C4CCCCC4S3)C5=NC6=CC=CC=C6S5	IC50 ~ 50000 nM	Poor binder
T72335	Bacterial Lethal factor	BDY45P	6-(1,4,5,6-Tetrahydropyrimidin-2-yl)-2-(4-(4-(1,4,5,6-tetrahydropyrimidin-2-yl)phenoxy)phenyl)-1H-indole	Investigative	45141820	C28H27N5O	449.5	C1CNC(=NC1)C2=CC=C(C=C2)OC3=CC=C(C=C3)C4=CC5=C(N4)C=C(C=C5)C6=NCCCN6	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BDZ28U	2-(4-Methoxyphenyl)-1H-indole-6-carboximidamide	Investigative	46228783	C22H19N3O2	357.4	COC1=CC=C(C=C1)OC2=CC=C(C=C2)C3=CC4=C(N3)C=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BEXN37	1-(4-Amino-2-methylquinolin-6-yl)-3-(4-phenylphenyl)urea	Investigative	73055306	C23H20N4O	368.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)NC3=CC=C(C=C3)C4=CC=CC=C4)N	IC50 = 79000 nM	Poor binder
T72335	Bacterial Lethal factor	BF0B7U	N-(4-Amino-2-methylquinolin-6-yl)pyridine-3-carboxamide	Investigative	73054453	C16H14N4O	278.31	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CN=CC=C3)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BF0W8I	N-Sec-Butyl-5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine	Investigative	46232312	C9H11N5O2S3	317.4	CCC(C)NC1=NN=C(S1)SC2=NC=C(S2)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BF24XA	2-(4-Fluorophenyl)-1H-indole-6-carboxamide	Investigative	46228744	C21H15FN2O2	346.4	C1=CC(=CC=C1C2=CC3=C(N2)C=C(C=C3)C(=O)N)OC4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BF7B1J	N-(3-(Benzo[d]thiazol-2-yl)-4-methylthiophen-2-yl)-3-(trifluoromethyl)-N-(3-(trifluoromethyl)phenylsulfonyl)benzenesulfonamide	Investigative	45269728	C26H16F6N2O4S4	662.7	CC1=CSC(=C1C2=NC3=CC=CC=C3S2)N(S(=O)(=O)C4=CC=CC(=C4)C(F)(F)F)S(=O)(=O)C5=CC=CC(=C5)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BFAM70	N-(3-(Benzo[d]thiazol-2-yl)isoxazol-5-yl)-4''-chlorobiphenyl-4-sulfonamide	Investigative	45273120	C22H14ClN3O3S2	468	C1=CC=C2C(=C1)N=C(S2)C3=C(ON=C3)NS(=O)(=O)C4=CC=C(C=C4)C5=CC=C(C=C5)Cl	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BFH4J1	4''-Chloro-N-(thiophen-2-yl)biphenyl-4-sulfonamide	Investigative	45270553	C16H12ClNO2S2	349.9	C1=CSC(=C1)NS(=O)(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)Cl	IC50 ~ 50000 nM	Poor binder
T72335	Bacterial Lethal factor	BFIW42	N-(4-Methyl-3-(trifluoromethyl)phenyl)thiophene-2-sulfonamide	Investigative	17432052	C12H10F3NO2S2	321.3	CC1=C(C=C(C=C1)NS(=O)(=O)C2=CC=CS2)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BFJ80V	2-(4-Methoxyphenyl)-1H-indole-6-carboxamide	Investigative	46228782	C22H18N2O3	358.4	COC1=CC=C(C=C1)OC2=CC=C(C=C2)C3=CC4=C(N3)C=C(C=C4)C(=O)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BFNV80	(Z)-2-(1H-Indol-2-yl)-3-(5-thiophen-2-ylthiophen-2-yl)prop-2-enenitrile	Investigative	57396753	C19H12N2S2	332.4	C1=CC=C2C(=C1)C=C(N2)/C(=C/C3=CC=C(S3)C4=CC=CS4)/C#N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BFQ86U	N-(4-Amino-2-methylquinolin-6-yl)-3-(4-chloro-2-methoxyphenyl)propanamide	Investigative	73056475	C20H20ClN3O2	369.8	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCC3=C(C=C(C=C3)Cl)OC)N	IC50 = 78000 nM	Poor binder
T72335	Bacterial Lethal factor	BFRK87	N-(3-(Benzo[d]thiazol-2-yl)-4-methylthiophen-2-yl)-4-tert-butylbenzenesulfonamide	Investigative	45267978	C22H22N2O2S3	442.6	CC1=CSC(=C1C2=NC3=CC=CC=C3S2)NS(=O)(=O)C4=CC=C(C=C4)C(C)(C)C	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BFWN45	N-(Benzo[d]thiazol-2-yl)-4''-methoxybiphenyl-4-sulfonamide	Investigative	45273112	C20H16N2O3S2	396.5	COC1=CC=C(C=C1)C2=CC=C(C=C2)S(=O)(=O)NC3=NC4=CC=CC=C4S3	IC50 ~ 50000 nM	Poor binder
T72335	Bacterial Lethal factor	BFX7D4	2-(1H-Benzoimidazol-2-yl)-3-(3,4,5-trimethoxy-phenyl)-acrylonitrile	Investigative	5754107	C19H17N3O3	335.4	COC1=CC(=CC(=C1OC)OC)/C=C(\\C#N)/C2=NC3=CC=CC=C3N2	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BG09FR	N-[3-(Trifluoromethyl)phenyl]-2-thiophenesulfonamide	Investigative	2880808	C11H8F3NO2S2	307.3	C1=CC(=CC(=C1)NS(=O)(=O)C2=CC=CS2)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BG3AC5	1-(4-Amino-2-methylquinolin-6-yl)-3-(1,3-benzodioxol-5-yl)urea	Investigative	73055305	C18H16N4O3	336.3	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)NC3=CC4=C(C=C3)OCO4)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BG5VF8	N-(4-Amino-2-methylquinolin-6-yl)-4-morpholin-4-ylbenzamide	Investigative	73054730	C21H22N4O2	362.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=C(C=C3)N4CCOCC4)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BGRY38	N-(4-Amino-2-methylquinolin-6-yl)-3-benzoylbenzamide	Investigative	73054452	C24H19N3O2	381.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=CC(=C3)C(=O)C4=CC=CC=C4)N	IC50 = 73000 nM	Poor binder
T72335	Bacterial Lethal factor	BH0S7Q	N-(4-Amino-2-methylquinolin-6-yl)-1-benzofuran-2-carboxamide	Investigative	73054733	C19H15N3O2	317.3	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC4=CC=CC=C4O3)N	IC50 = 90000 nM	Poor binder
T72335	Bacterial Lethal factor	BH21JY	N-(4-Amino-2-methylquinolin-6-yl)-3-(2-ethoxyphenyl)propanamide	Investigative	73056477	C21H23N3O2	349.4	CCOC1=CC=CC=C1CCC(=O)NC2=CC3=C(C=C(N=C3C=C2)C)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BH21MR	N-(4-Amino-2-methylquinolin-6-yl)-2-phenylacetamide	Investigative	234080	C18H17N3O	291.3	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CC3=CC=CC=C3)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BI1QE8	N-(3-(Benzo[d]thiazol-2-yl)thiopen-2-yl)-4-(2-methoxyphenoxy)benzenesulfonamide	Investigative	45271421	C24H18N2O4S3	494.6	COC1=CC=CC=C1OC2=CC=C(C=C2)S(=O)(=O)NC3=C(C=CS3)C4=NC5=CC=CC=C5S4	IC50 ~ 50000 nM	Poor binder
T72335	Bacterial Lethal factor	BJ0A4F	N-(3-(Benzo[d]thiazol-2-yl)isoxazol-5-yl)-4''-methoxybiphenyl-4-sulfonamide	Investigative	45270540	C23H17N3O4S2	463.5	COC1=CC=C(C=C1)C2=CC=C(C=C2)S(=O)(=O)NC3=C(C=NO3)C4=NC5=CC=CC=C5S4	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BJ7P1H	3-(1,3-Benzothiazol-2-yl)thiophen-2-amine	Investigative	2735416	C11H8N2S2	232.3	C1=CC=C2C(=C1)N=C(S2)C3=C(SC=C3)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BJM5H0	(2E)-2-(1H-Benzimidazol-2-yl)-3-(3-iodo-4-methoxyphenyl)prop-2-enenitrile	Investigative	5941957	C17H12IN3O	401.2	COC1=C(C=C(C=C1)/C=C(\\C#N)/C2=NC3=CC=CC=C3N2)I	IC50 = 74000 nM	Poor binder
T72335	Bacterial Lethal factor	BJW5Q1	2-(1H-Benzoimidazol-2-yl)-3-(5-methyl-thiophen-2-yl)-acrylonitrile	Investigative	5738327	C15H11N3S	265.3	CC1=CC=C(S1)/C=C(\\C#N)/C2=NC3=CC=CC=C3N2	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BK3VH1	N-[3-(1,3-Benzothiazol-2-yl)thiophen-2-yl]-5-methyl-1-phenylpyrazole-4-sulfonamide	Investigative	45267963	C21H16N4O2S3	452.6	CC1=C(C=NN1C2=CC=CC=C2)S(=O)(=O)NC3=C(C=CS3)C4=NC5=CC=CC=C5S4	IC50 ~ 50000 nM	Poor binder
T72335	Bacterial Lethal factor	BL2FX1	(E)-2-(1H-Benzimidazol-2-yl)-3-[4-(1H-imidazol-2-yl)phenyl]prop-2-enenitrile	Investigative	57402018	C19H13N5	311.3	C1=CC=C2C(=C1)NC(=N2)/C(=C/C3=CC=C(C=C3)C4=NC=CN4)/C#N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BL39YC	8-[(4-Fluoro-3-methylphenyl)sulfonyl-[(2R)-1-(hydroxyamino)-1-oxopropan-2-yl]amino]octanoic acid	Investigative	122196500	C18H27FN2O6S	418.5	CC1=C(C=CC(=C1)S(=O)(=O)N(CCCCCCCC(=O)O)[C@H](C)C(=O)NO)F	IC50 = 91000 nM	Poor binder
T72335	Bacterial Lethal factor	BLE6V2	N-(4-Amino-2-methylquinolin-6-yl)-3-(2,5-dimethoxyphenyl)propanamide	Investigative	73055301	C21H23N3O3	365.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCC3=C(C=CC(=C3)OC)OC)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BLU32M	2-Chloro-5-[5-[(E)-[2-(3-chloro-4-methylphenyl)imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]benzoic acid	Investigative	136043847	C22H14Cl2N2O4S	473.3	CC1=C(C=C(C=C1)N=C2NC(=O)/C(=C\\C3=CC=C(O3)C4=CC(=C(C=C4)Cl)C(=O)O)/S2)Cl	IC50 = 50000 nM	Poor binder
T72335	Bacterial Lethal factor	BM95PA	N-(4-Amino-2-methylquinolin-6-yl)-2-(1,3-benzodioxol-5-yl)acetamide	Investigative	73055017	C19H17N3O3	335.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CC3=CC4=C(C=C3)OCO4)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BN5O9K	3-Chloro-4-[4-[6-(4,5-dihydro-1H-imidazol-2-yl)-1H-indol-2-yl]phenoxy]benzonitrile	Investigative	45139631	C24H17ClN4O	412.9	C1CN=C(N1)C2=CC3=C(C=C2)C=C(N3)C4=CC=C(C=C4)OC5=C(C=C(C=C5)C#N)Cl	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BO4VH3	2-[4-[4-[6-(5-Hydroxy-1,4,5,6-tetrahydropyrimidin-2-yl)-1H-indol-2-yl]phenoxy]phenyl]-1,4,5,6-tetrahydropyrimidin-5-ol	Investigative	45141821	C28H27N5O3	481.5	C1C(CN=C(N1)C2=CC=C(C=C2)OC3=CC=C(C=C3)C4=CC5=C(N4)C=C(C=C5)C6=NCC(CN6)O)O	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BO5HB9	N-(3-(Benzo[d]thiazol-2-yl)thiophen-2-yl)furan-2-sulfonamide	Investigative	45267122	C15H10N2O3S3	362.5	C1=CC=C2C(=C1)N=C(S2)C3=C(SC=C3)NS(=O)(=O)C4=CC=CO4	IC50 ~ 50000 nM	Poor binder
T72335	Bacterial Lethal factor	BOC5P2	(5E)-5-[[5-(4-Chlorophenyl)furan-2-yl]methylidene]-2-imino-1-methylimidazolidin-4-one	Investigative	137628929	C15H12ClN3O2	301.73	CN1/C(=C/C2=CC=C(O2)C3=CC=C(C=C3)Cl)/C(=O)NC1=N	IC50 = 199526.23 nM	Poor binder
T72335	Bacterial Lethal factor	BP1E2C	[2-[3-[(4-Amino-2-methylquinolin-6-yl)amino]-3-oxopropyl]phenyl] benzoate	Investigative	73055303	C26H23N3O3	425.5	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCC3=CC=CC=C3OC(=O)C4=CC=CC=C4)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BP83UI	3-(1,3-Benzothiazol-2-yl)-4-methylthiophen-2-amine	Investigative	2735376	C12H10N2S2	246.4	CC1=CSC(=C1C2=NC3=CC=CC=C3S2)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BP8K0Z	1-(4-Amino-2-methylquinolin-6-yl)-3-[(2-methoxyphenyl)methyl]urea	Investigative	73055607	C19H20N4O2	336.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)NCC3=CC=CC=C3OC)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BQE86U	(E)-2-(1H-Benzimidazol-2-yl)-3-(4-nitro-1H-indol-3-yl)prop-2-enenitrile	Investigative	136042248	C18H11N5O2	329.3	C1=CC=C2C(=C1)NC(=N2)/C(=C/C3=CNC4=C3C(=CC=C4)[N+](=O)[O-])/C#N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BQI61R	N-(4-Amino-2-methylquinolin-6-yl)-3-(4-fluorophenyl)propanamide	Investigative	73056184	C19H18FN3O	323.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCC3=CC=C(C=C3)F)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BQT1U8	N-(3-(Benzo[d]thiazol-2-yl)-4-methylthiophen-2-yl)-4-(trifluoromethoxy)-N-(4-(trifluoromethoxy)phenylsulfonyl)benzenesulfonamide	Investigative	45270555	C26H16F6N2O6S4	694.7	CC1=CSC(=C1C2=NC3=CC=CC=C3S2)N(S(=O)(=O)C4=CC=C(C=C4)OC(F)(F)F)S(=O)(=O)C5=CC=C(C=C5)OC(F)(F)F	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BQV01A	N-(3-(Benzo[d]thiazol-2-yl)-4-methylthiophen-2-yl)-3-chloro-2-fluorobenzenesulfonamide	Investigative	45271357	C18H12ClFN2O2S3	439	CC1=CSC(=C1C2=NC3=CC=CC=C3S2)NS(=O)(=O)C4=C(C(=CC=C4)Cl)F	IC50 = 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BRAE17	2-[(1S,2R,4R,5R)-2-(2-Amino-3H-benzimidazol-5-yl)-5-(diaminomethylideneamino)-4-hydroxycyclohexyl]guanidine	Investigative	44409120	C15H23N9O	345.4	C1[C@@H]([C@H](C[C@H]([C@@H]1O)N=C(N)N)N=C(N)N)C2=CC3=C(C=C2)N=C(N3)N	Ki = 153700 nM	Poor binder
T72335	Bacterial Lethal factor	BS2C0I	N-(4-Amino-2-methylquinolin-6-yl)-N'-(4-methoxyphenyl)urea	Investigative	59079459	C18H18N4O2	322.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)NC3=CC=C(C=C3)OC)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BSCY59	N-(2-(Benzo[d]thiazol-2-yl)phenyl)-4''-methoxybiphenyl-4-sulfonamide	Investigative	45272261	C26H20N2O3S2	472.6	COC1=CC=C(C=C1)C2=CC=C(C=C2)S(=O)(=O)NC3=CC=CC=C3C4=NC5=CC=CC=C5S4	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BT76UP	N-(4-Amino-2-methylquinolin-6-yl)-3-(dimethylamino)benzamide	Investigative	73054455	C19H20N4O	320.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC(=CC=C3)N(C)C)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BT7QR2	6-Chloro-2-(4-(4-(4,5-dihydro-1H-imidazol-2-yl)phenoxy)-phenyl)-1H-indole	Investigative	45142030	C23H18ClN3O	387.9	C1CN=C(N1)C2=CC=C(C=C2)OC3=CC=C(C=C3)C4=CC5=C(N4)C=C(C=C5)Cl	IC50 = 51000 nM	Poor binder
T72335	Bacterial Lethal factor	BTGF37	N-(4-Amino-2-methylquinolin-6-yl)-3-(4-bromo-2-methoxyphenyl)propanamide	Investigative	73056476	C20H20BrN3O2	414.3	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCC3=C(C=C(C=C3)Br)OC)N	IC50 = 58000 nM	Poor binder
T72335	Bacterial Lethal factor	BTVR09	1-(4-Amino-2-methylquinolin-6-yl)-3-(4-fluorophenyl)urea	Investigative	73055603	C17H15FN4O	310.33	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)NC3=CC=C(C=C3)F)N	IC50 = 95000 nM	Poor binder
T72335	Bacterial Lethal factor	BTX7U2	N-(3-(Benzo[d]thiazol-2-yl)-4-methylthiophen-2-yl)-2-(trifluoromethyl)benzenesulfonamide	Investigative	45269681	C19H13F3N2O2S3	454.5	CC1=CSC(=C1C2=NC3=CC=CC=C3S2)NS(=O)(=O)C4=CC=CC=C4C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BU0WZ1	(E)-2-(1H-Benzimidazol-2-yl)-3-(4-phenylphenyl)prop-2-enenitrile	Investigative	5915017	C22H15N3	321.4	C1=CC=C(C=C1)C2=CC=C(C=C2)/C=C(\\C#N)/C3=NC4=CC=CC=C4N3	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BUHM40	Ethyl 4-[(4-amino-2-methylquinolin-6-yl)carbamoylamino]benzoate	Investigative	73055602	C20H20N4O3	364.4	CCOC(=O)C1=CC=C(C=C1)NC(=O)NC2=CC3=C(C=C(N=C3C=C2)C)N	IC50 = 87000 nM	Poor binder
T72335	Bacterial Lethal factor	BULY82	1H-Imidazole, 4,5-dihydro-2-(4-(6-(4,5-dihydro-1H-imidazol-2-yl)benzo(b)thien-2-yl)phenyl)-	Investigative	206023	C20H18N4S	346.5	C1CN=C(N1)C2=CC=C(C=C2)C3=CC4=C(S3)C=C(C=C4)C5=NCCN5	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BUS60M	(E)-2-(1H-Benzimidazol-2-yl)-3-(5-thiophen-2-ylfuran-2-yl)prop-2-enenitrile	Investigative	57400217	C18H11N3OS	317.4	C1=CC=C2C(=C1)NC(=N2)/C(=C/C3=CC=C(O3)C4=CC=CS4)/C#N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BV2DZ3	N-(3-(Benzo[d]thiazol-2-yl)-4-methylthiophen-2-yl)-4-fluorobenzenesulfonamide	Investigative	45269689	C18H13FN2O2S3	404.5	CC1=CSC(=C1C2=NC3=CC=CC=C3S2)NS(=O)(=O)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BVA4P5	N-(2-(Benzo[d]thiazol-2-yl)phenyl)-4''-chlorobiphenyl-4-sulfonamide	Investigative	45268001	C25H17ClN2O2S2	477	C1=CC=C(C(=C1)C2=NC3=CC=CC=C3S2)NS(=O)(=O)C4=CC=C(C=C4)C5=CC=C(C=C5)Cl	IC50 = 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BVT98R	N-(2-(Benzo[d]thiazol-2-yl)ethyll)-4''-chlorobiphenyl-4-sulfonamide	Investigative	45273121	C21H17ClN2O2S2	429	C1=CC=C2C(=C1)N=C(S2)CCNS(=O)(=O)C3=CC=C(C=C3)C4=CC=C(C=C4)Cl	IC50 ~ 50000 nM	Poor binder
T72335	Bacterial Lethal factor	BW5Y1M	(E)-2-(1H-Benzimidazol-2-yl)-3-(3-fluoro-4-methoxyphenyl)prop-2-enenitrile	Investigative	40669841	C17H12FN3O	293.29	COC1=C(C=C(C=C1)/C=C(\\C#N)/C2=NC3=CC=CC=C3N2)F	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BW69UD	(E)-2-(1,3-Benzothiazol-2-yl)-3-(5-thiophen-2-ylthiophen-2-yl)prop-2-enenitrile	Investigative	57395004	C18H10N2S3	350.5	C1=CC=C2C(=C1)N=C(S2)/C(=C/C3=CC=C(S3)C4=CC=CS4)/C#N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BW7JN5	N-(2,4,5-Trihydroxyphenethyl)oleamide	Investigative	44441631	C26H43NO4	433.6	CCCCCCCC/C=C\\CCCCCCCC(=O)NCCC1=CC(=C(C=C1O)O)O	IC50 = 70000 nM	Poor binder
T72335	Bacterial Lethal factor	BWI06P	2-(4-(4-Cyanophenoxy)phenyl)-1H-indole-6-carboximidamide	Investigative	45141818	C22H16N4O	352.4	C1=CC(=CC=C1C#N)OC2=CC=C(C=C2)C3=CC4=C(N3)C=C(C=C4)C(=N)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BWI6B3	N-(4-Amino-2-methylquinolin-6-yl)-3-(4-methoxypyridin-3-yl)propanamide	Investigative	73056774	C19H20N4O2	336.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCC3=C(C=CN=C3)OC)N	IC50 ~ 50000 nM	Poor binder
T72335	Bacterial Lethal factor	BWT1D3	2-(1H-Benzoimidazol-2-yl)-3-thiophen-2-yl-acrylonitrile	Investigative	5334847	C14H9N3S	251.31	C1=CC=C2C(=C1)NC(=N2)/C(=C/C3=CC=CS3)/C#N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BWY62U	3-[1-(3-Hydroxyphenyl)-5-(2-thienyl)pyrrol-2-yl]propanoic acid	Investigative	670897	C17H15NO3S	313.4	C1=CC(=CC(=C1)O)N2C(=CC=C2C3=CC=CS3)CCC(=O)O	IC50 = 60000 nM	Poor binder
T72335	Bacterial Lethal factor	BX21QJ	N-(3-(Benzo[d]thiazol-2-yl)thiopen-2-yl)-3-chloro-2-methylbenzenesulfonamide	Investigative	45270578	C18H13ClN2O2S3	421	CC1=C(C=CC=C1Cl)S(=O)(=O)NC2=C(C=CS2)C3=NC4=CC=CC=C4S3	IC50 ~ 50000 nM	Poor binder
T72335	Bacterial Lethal factor	BX2I8M	2-(5-Fluoro-2-pyridyl)-6-benzo[b]thiophenecarboxamide	Investigative	46228836	C20H13FN2O2S	364.4	C1=CC(=CC=C1C2=NC3=C(S2)C=C(C=C3)C(=O)N)OC4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BX8BO1	N-(4-Amino-2-methylquinolin-6-yl)furan-2-carboxamide	Investigative	73054454	C15H13N3O2	267.28	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=CO3)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BX8ZC7	(2R)-2-[(4-Fluoro-3-methylphenyl)sulfonyl-propan-2-ylamino]-N-hydroxypropanamide	Investigative	122196487	C13H19FN2O4S	318.37	CC1=C(C=CC(=C1)S(=O)(=O)N([C@H](C)C(=O)NO)C(C)C)F	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BXE12U	N-(4-Amino-2-methylquinolin-6-yl)-3-(3-methoxythiophen-2-yl)propanamide	Investigative	73056775	C18H19N3O2S	341.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CCC3=C(C=CS3)OC)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BXYH20	[(5E)-5-[[5-(4-Chlorophenyl)furan-2-yl]methylidene]-1-methyl-4-oxoimidazolidin-2-yl]carbamic acid	Investigative	44406615	C16H14ClN3O4	347.75	CN\\1C(NC(=O)/C1=C\\C2=CC=C(O2)C3=CC=C(C=C3)Cl)NC(=O)O	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BY1JD8	N-(4-Amino-2-methylquinolin-6-yl)-4-phenoxybenzamide	Investigative	73054451	C23H19N3O2	369.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C3=CC=C(C=C3)OC4=CC=CC=C4)N	IC50 = 70000 nM	Poor binder
T72335	Bacterial Lethal factor	BY31SW	N-(3-(Benzo[d]thiazol-2-yl)-4-methylthiophen-2-yl)-3-chloro-2-methylbenzenesulfonamide	Investigative	45269701	C19H15ClN2O2S3	435	CC1=CSC(=C1C2=NC3=CC=CC=C3S2)NS(=O)(=O)C4=C(C(=CC=C4)Cl)C	IC50 = 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BYD6Q4	N-(3-(Benzo[d]thiazol-2-yl)-4-methylthiophen-2-yl)-3,4-dichlorobenzenesulfonamide	Investigative	45267979	C18H12Cl2N2O2S3	455.4	CC1=CSC(=C1C2=NC3=CC=CC=C3S2)NS(=O)(=O)C4=CC(=C(C=C4)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BYIW29	(E)-2-(1H-Benzimidazol-2-yl)-3-(3-methyl-1-benzothiophen-2-yl)prop-2-enenitrile	Investigative	57402019	C19H13N3S	315.4	CC1=C(SC2=CC=CC=C12)/C=C(\\C#N)/C3=NC4=CC=CC=C4N3	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BYL13U	(E)-2-(1H-Benzimidazol-2-yl)-3-(4,5-dimethylthiophen-2-yl)prop-2-enenitrile	Investigative	57395030	C16H13N3S	279.4	CC1=C(SC(=C1)/C=C(\\C#N)/C2=NC3=CC=CC=C3N2)C	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BYS0L8	(E)-2-(1H-Benzimidazol-2-yl)-3-(4-methoxyphenyl)prop-2-enenitrile	Investigative	5286524	C17H13N3O	275.3	COC1=CC=C(C=C1)/C=C(\\C#N)/C2=NC3=CC=CC=C3N2	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BZAX83	N-(4-Amino-2-methylquinolin-6-yl)-2-(2-methoxyphenyl)acetamide	Investigative	73056479	C19H19N3O2	321.4	CC1=CC(=C2C=C(C=CC2=N1)NC(=O)CC3=CC=CC=C3OC)N	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BZL1M8	2-(4-(4-(6-(1,4,5,6-Tetrahydropyrimidin-2-yl)benzo[b]thiophen-2-yl)phenoxy)phenyl)-1,4,5,6-tetrahydropyrimidine	Investigative	45139633	C28H26N4OS	466.6	C1CNC(=NC1)C2=CC=C(C=C2)OC3=CC=C(C=C3)C4=CC5=C(S4)C=C(C=C5)C6=NCCCN6	IC50 ~ 100000 nM	Poor binder
T72335	Bacterial Lethal factor	BZT2J7	(4-Oxo-5-thiophen-2-ylmethylene-2-thioxo-thiazolidin-3-yl)-acetic acid	Investigative	1201190	C10H7NO3S3	285.4	C1=CSC(=C1)/C=C\\2/C(=O)N(C(=S)S2)CC(=O)O	IC50 = 79400 nM	Poor binder