TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T73184	Histone-lysine N-methyltransferase SETD7	B0A4UL	N-(2-Methoxybenzyl)-1-(3-((2-(methylamino)ethylamino)methyl)phenyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide	Investigative	25216415	C23H26F3N5O2	461.5	CNCCNCC1=CC(=CC=C1)N2C(=CC(=N2)C(F)(F)F)C(=O)NCC3=CC=CC=C3OC	IC50 ~ 100000 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	B12ZLA	1-Methyl-4-(9h-xanthen-9-yl)piperazine	Investigative	230362	C18H20N2O	280.4	CN1CCN(CC1)C2C3=CC=CC=C3OC4=CC=CC=C24	IC50 ~ 100000 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	B29ZVO	6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine	Investigative	78357767	C23H35N5O2	413.6	COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCCC3)NCCCCCN4CCCC4)OC	IC50 ~ 100000 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	B50VDG	4-(10,11-Dihydro-5-dibenzo[a,d]cycloheptenylidene)-1-methylpiperidine	Investigative	168897	C21H23N	289.4	CN1CCC(=C2C3=CC=CC=C3CCC4=CC=CC=C42)CC1	IC50 = 59100 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	B5U8YP	1-Methyl-4-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenyloxy)piperidine	Investigative	13750139	C21H23NO	305.4	CN1CCC(CC1)OC2C3=CC=CC=C3C=CC4=CC=CC=C24	IC50 ~ 100000 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	B7O6AT	Cyproheptadine M (nor), acetylated	Investigative	524039	C22H21NO	315.4	CC(=O)N1CCC(=C2C3=CC=CC=C3C=CC4=CC=CC=C42)CC1	IC50 ~ 100000 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	BA3U1I	Piperidine, 4-(diphenylmethylene)-1-methyl-	Investigative	95734	C19H21N	263.4	CN1CCC(=C(C2=CC=CC=C2)C3=CC=CC=C3)CC1	IC50 = 94600 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	BCUI39	1-Methyl-4-(9H-thioxanthen-9-yl)piperazine	Investigative	127044062	C18H20N2S	296.4	CN1CCN(CC1)C2C3=CC=CC=C3SC4=CC=CC=C24	IC50 ~ 100000 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	BF62YG	N-(3-Nitrophenyl)-5-methylfuran-3-carboxamide	Investigative	122192598	C12H10N2O4	246.22	CC1=CC(=CO1)C(=O)NC2=CC(=CC=C2)[N+](=O)[O-]	IC50 = 89180 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	BG4RJ3	Ethyl 2-amino-5-[(3-cyanophenyl)carbamoyl]-4-methylthiophene-3-carboxylate	Investigative	122192761	C16H15N3O3S	329.4	CCOC(=O)C1=C(SC(=C1C)C(=O)NC2=CC=CC(=C2)C#N)N	IC50 = 61550 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	BG9XH8	(3E,5E)-3,5-Bis[(3-bromo-4-hydroxyphenyl)methylidene]-1-[(3-chlorophenyl)methyl]piperidin-4-one	Investigative	53361222	C26H20Br2ClNO3	589.7	C\\1N(C/C(=C\\C2=CC(=C(C=C2)O)Br)/C(=O)/C1=C/C3=CC(=C(C=C3)O)Br)CC4=CC(=CC=C4)Cl	IC50 = 174000 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	BN28TW	N-(3-Nitrophenyl)-1,3-benzodioxole-5-carboxamide	Investigative	5237229	C14H10N2O5	286.24	C1OC2=C(O1)C=C(C=C2)C(=O)NC3=CC(=CC=C3)[N+](=O)[O-]	IC50 = 61750 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	BNO96V	(S)-1-(5-((2-Aminopropanamido)methyl)thiophen-3-yl)-N-(2-methoxybenzyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide	Investigative	25218467	C21H22F3N5O3S	481.5	C[C@@H](C(=O)NCC1=CC(=CS1)N2C(=CC(=N2)C(F)(F)F)C(=O)NCC3=CC=CC=C3OC)N	IC50 ~ 100000 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	BO5RS7	N-[4-(4-Aminophenyl)sulfonylphenyl]-4-phenylbenzamide	Investigative	56673504	C25H20N2O3S	428.5	C1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)NC3=CC=C(C=C3)S(=O)(=O)C4=CC=C(C=C4)N	IC50 = 66400 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	BPT87C	Methyl 2-[[2-[(6-methoxy-1H-benzimidazol-2-yl)sulfanyl]acetyl]amino]benzoate	Investigative	1002773	C18H17N3O4S	371.4	COC1=CC2=C(C=C1)N=C(N2)SCC(=O)NC3=CC=CC=C3C(=O)OC	IC50 ~ 100000 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	BS9W8F	4-Methyl-3-nitro-N-(3-nitrophenyl)benzamide	Investigative	1740582	C14H11N3O5	301.25	CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC=C2)[N+](=O)[O-])[N+](=O)[O-]	IC50 = 189700 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	BT4O1F	1-Methyl-4-(9H-xanthen-9-yloxy)piperidine	Investigative	127044063	C19H21NO2	295.4	CN1CCC(CC1)OC2C3=CC=CC=C3OC4=CC=CC=C24	IC50 ~ 100000 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	BT8YF6	1-(11H-Dibenzo[1,2-a:1',2'-e][7]annulen-11-yl)-4-methylpiperazine	Investigative	20232228	C20H22N2	290.4	CN1CCN(CC1)C2C3=CC=CC=C3C=CC4=CC=CC=C24	IC50 ~ 100000 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	BU24HE	1-Methyl-4-(9H-thioxanthen-9-yloxy)piperidine	Investigative	127045421	C19H21NOS	311.4	CN1CCC(CC1)OC2C3=CC=CC=C3SC4=CC=CC=C24	IC50 ~ 100000 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	BV61WA	1-((2-(1H-Indol-3-yl)ethyl)amino)-3-(9H-carbazol-9-yl)-propan-2-ol	Investigative	16451230	C25H25N3O	383.5	C1=CC=C2C(=C1)C(=CN2)CCNCC(CN3C4=CC=CC=C4C5=CC=CC=C53)O	IC50 ~ 150000 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	BVZ6Y5	(3E,5E)-3,5-Bis[(3-bromo-4-hydroxyphenyl)methylidene]-1-phenacylpiperidin-4-one	Investigative	53361223	C27H21Br2NO4	583.3	C\\1N(C/C(=C\\C2=CC(=C(C=C2)O)Br)/C(=O)/C1=C/C3=CC(=C(C=C3)O)Br)CC(=O)C4=CC=CC=C4	IC50 = 149000 nM	Poor binder
T73184	Histone-lysine N-methyltransferase SETD7	D02TVQ	GSK343	Investigative	71268957	C31H39N7O2	541.7	CCCC1=C(C(=O)NC(=C1)C)CNC(=O)C2=C3C=NN(C3=CC(=C2)C4=CC(=NC=C4)N5CCN(CC5)C)C(C)C	IC50 = 63000 nM	Poor binder