TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T74238	Leukotriene CysLT2 receptor	D05DVP	Zafirlukast	Approved	5717	C31H33N3O6S	575.7	CC1=CC=CC=C1S(=O)(=O)NC(=O)C2=CC(=C(C=C2)CC3=CN(C4=C3C=C(C=C4)NC(=O)OC5CCCC5)C)OC	IC50 = 58000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	B13MTJ	4,6-Dichloro-3-[(E)-3-[[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]methoxy]-3-oxoprop-1-enyl]-1H-indole-2-carboxylic acid	Investigative	127043252	C30H19Cl3N2O4	577.8	C1=CC(=CC(=C1)/C=C/C2=NC3=C(C=CC(=C3)Cl)C=C2)COC(=O)/C=C/C4=C(NC5=C4C(=CC(=C5)Cl)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	B1KU8T	4,6-Dichloro-3-[(E)-3-(4-cyanobutoxy)-3-oxoprop-1-enyl]-1H-indole-2-carboxylic acid	Investigative	127045343	C17H14Cl2N2O4	381.2	C1=C(C=C(C2=C1NC(=C2/C=C/C(=O)OCCCCC#N)C(=O)O)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	B1YJL7	4,6-Dichloro-3-[(E)-3-oxo-3-phenoxyprop-1-enyl]-1H-indole-2-carboxylic acid	Investigative	127043253	C18H11Cl2NO4	376.2	C1=CC=C(C=C1)OC(=O)/C=C/C2=C(NC3=C2C(=CC(=C3)Cl)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	B2M4ZE	4,6-Dichloro-3-[(E)-3-cyclohexyloxy-3-oxoprop-1-enyl]-1H-indole-2-carboxylic acid	Investigative	127043410	C18H17Cl2NO4	382.2	C1CCC(CC1)OC(=O)/C=C/C2=C(NC3=C2C(=CC(=C3)Cl)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	B4FU5J	5-Chloro-3-[(E)-3-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]anilino]-3-oxoprop-1-enyl]-1H-indole-2-carboxylic acid	Investigative	127043241	C29H19Cl2N3O3	528.4	C1=CC(=CC(=C1)NC(=O)/C=C/C2=C(NC3=C2C=C(C=C3)Cl)C(=O)O)/C=C/C4=NC5=C(C=CC(=C5)Cl)C=C4	IC50 ~ 100000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	B4H3KX	3-[(E)-3-[[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl]methoxy]-3-oxoprop-1-enyl]-1H-indole-2-carboxylic acid	Investigative	127043233	C30H21ClN2O4	508.9	C1=CC=C2C(=C1)C(=C(N2)C(=O)O)/C=C/C(=O)OCC3=CC(=CC=C3)/C=C/C4=NC5=C(C=CC(=C5)Cl)C=C4	IC50 ~ 100000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	B5QNI1	4,6-Dichloro-3-[(E)-3-(cyclohexylmethoxy)-3-oxoprop-1-enyl]-1H-indole-2-carboxylic acid	Investigative	127045334	C19H19Cl2NO4	396.3	C1CCC(CC1)COC(=O)/C=C/C2=C(NC3=C2C(=CC(=C3)Cl)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	B7DN8P	4,6-Dichloro-3-[(E)-3-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]anilino]-3-oxoprop-1-enyl]-1H-indole-2-carboxylic acid	Investigative	127043049	C29H18Cl3N3O3	562.8	C1=CC(=CC(=C1)NC(=O)/C=C/C2=C(NC3=C2C(=CC(=C3)Cl)Cl)C(=O)O)/C=C/C4=NC5=C(C=CC(=C5)Cl)C=C4	IC50 ~ 100000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	B7JU2N	4,6-Dichloro-3-[(E)-3-oxo-3-pentoxyprop-1-enyl]-1H-indole-2-carboxylic acid	Investigative	127043411	C17H17Cl2NO4	370.2	CCCCCOC(=O)/C=C/C1=C(NC2=C1C(=CC(=C2)Cl)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	B84FEX	4,6-Dichloro-3-[(E)-3-oxo-3-(3-phenylpropoxy)prop-1-enyl]-1H-indole-2-carboxylic acid	Investigative	127043408	C21H17Cl2NO4	418.3	C1=CC=C(C=C1)CCCOC(=O)/C=C/C2=C(NC3=C2C(=CC(=C3)Cl)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	B87FVK	6-Chloro-3-[(E)-3-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]anilino]-3-oxoprop-1-enyl]-1H-indole-2-carboxylic acid	Investigative	127043242	C29H19Cl2N3O3	528.4	C1=CC(=CC(=C1)NC(=O)/C=C/C2=C(NC3=C2C=CC(=C3)Cl)C(=O)O)/C=C/C4=NC5=C(C=CC(=C5)Cl)C=C4	IC50 = 87000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	B8ITB9	[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl]methyl (E)-3-(4,6-dichloro-1H-indol-3-yl)prop-2-enoate	Investigative	127043048	C29H19Cl3N2O2	533.8	C1=CC(=CC(=C1)/C=C/C2=NC3=C(C=CC(=C3)Cl)C=C2)COC(=O)/C=C/C4=CNC5=C4C(=CC(=C5)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	B9OJ8Z	3-[(E)-3-[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]anilino]-3-oxoprop-1-enyl]-6-methoxy-1H-indole-2-carboxylic acid	Investigative	127043617	C30H22ClN3O4	524	COC1=CC2=C(C=C1)C(=C(N2)C(=O)O)/C=C/C(=O)NC3=CC=CC(=C3)/C=C/C4=NC5=C(C=CC(=C5)Cl)C=C4	IC50 ~ 100000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	BC7ZU0	3-[(E)-3-[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]anilino]-3-oxoprop-1-enyl]-4,6-difluoro-1H-indole-2-carboxylic acid	Investigative	127043247	C29H18ClF2N3O3	529.9	C1=CC(=CC(=C1)NC(=O)/C=C/C2=C(NC3=C2C(=CC(=C3)F)F)C(=O)O)/C=C/C4=NC5=C(C=CC(=C5)Cl)C=C4	IC50 = 76000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	BM5Q1T	4,6-Dichloro-3-[(E)-3-(4-methylpentoxy)-3-oxoprop-1-enyl]-1H-indole-2-carboxylic acid	Investigative	127044872	C18H19Cl2NO4	384.2	CC(C)CCCOC(=O)/C=C/C1=C(NC2=C1C(=CC(=C2)Cl)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	BMI51N	4,6-Dichloro-3-[(E)-3-oxo-3-phenylmethoxyprop-1-enyl]-1H-indole-2-carboxylic acid	Investigative	127043406	C19H13Cl2NO4	390.2	C1=CC=C(C=C1)COC(=O)/C=C/C2=C(NC3=C2C(=CC(=C3)Cl)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	BT4A6B	3-[3-[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]anilino]-3-oxopropyl]-1H-indole-2-carboxylic acid	Investigative	127043237	C29H22ClN3O3	496	C1=CC=C2C(=C1)C(=C(N2)C(=O)O)CCC(=O)NC3=CC=CC(=C3)/C=C/C4=NC5=C(C=CC(=C5)Cl)C=C4	IC50 = 50000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	BTWJ54	3-[(E)-3-[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]anilino]-3-oxoprop-1-enyl]-1H-indole-2-carboxylic acid	Investigative	127043050	C29H20ClN3O3	493.9	C1=CC=C2C(=C1)C(=C(N2)C(=O)O)/C=C/C(=O)NC3=CC=CC(=C3)/C=C/C4=NC5=C(C=CC(=C5)Cl)C=C4	IC50 = 58000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	BW4CJ9	4,6-Dichloro-3-[(E)-3-oxo-3-(4-phenylbutoxy)prop-1-enyl]-1H-indole-2-carboxylic acid	Investigative	127043409	C22H19Cl2NO4	432.3	C1=CC=C(C=C1)CCCCOC(=O)/C=C/C2=C(NC3=C2C(=CC(=C3)Cl)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	BWJO05	7-Chloro-3-[(E)-3-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]anilino]-3-oxoprop-1-enyl]-1H-indole-2-carboxylic acid	Investigative	127043243	C29H19Cl2N3O3	528.4	C1=CC(=CC(=C1)NC(=O)/C=C/C2=C(NC3=C2C=CC=C3Cl)C(=O)O)/C=C/C4=NC5=C(C=CC(=C5)Cl)C=C4	IC50 ~ 100000 nM	Poor binder
T74238	Leukotriene CysLT2 receptor	BYJC43	4,6-Dichloro-3-[(E)-3-oxo-3-(2-phenylethoxy)prop-1-enyl]-1H-indole-2-carboxylic acid	Investigative	127043407	C20H15Cl2NO4	404.2	C1=CC=C(C=C1)CCOC(=O)/C=C/C2=C(NC3=C2C(=CC(=C3)Cl)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder