TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T74312	Fms-like tyrosine kinase 3	D0J9ZR	Niclosamide	Approved	4477	C13H8Cl2N2O4	327.12	C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O	IC50 ~ 100000 nM	Poor binder
T74312	Fms-like tyrosine kinase 3	B1UH5K	1-Cyclohexyl-2,3,4,7-tetrahydro-1H-pyrrolo[2,3-h][1,6]naphthyridine	Investigative	58557147	C16H21N3	255.36	C1CCC(CC1)N2CCCC3=CN=C4C(=C32)C=CN4	IC50 ~ 50000 nM	Poor binder
T74312	Fms-like tyrosine kinase 3	B43WPI	3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2R)-2,3-dihydroxypropyl]-4-methoxybenzamide	Investigative	57325478	C19H20ClNO4	361.8	COC1=C(C=C(C=C1)C(=O)NC[C@H](CO)O)/C=C/C2=CC=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T74312	Fms-like tyrosine kinase 3	B58TMC	[6-Chloro-4-methyl-3-[[3-(methylsulfamoylamino)phenyl]methyl]-2-oxochromen-7-yl] N,N-dimethylcarbamate	Investigative	24753787	C21H22ClN3O6S	479.9	CC1=C(C(=O)OC2=CC(=C(C=C12)Cl)OC(=O)N(C)C)CC3=CC(=CC=C3)NS(=O)(=O)NC	IC50 ~ 50000 nM	Poor binder
T74312	Fms-like tyrosine kinase 3	B72RGX	N-(3-Chlorophenyl)-7-(2-chloro-2-phenylethyl)-2-methylsulfanylpyrrolo[2,3-d]pyrimidin-4-amine	Investigative	25195515	C21H18Cl2N4S	429.4	CSC1=NC(=C2C=CN(C2=N1)CC(C3=CC=CC=C3)Cl)NC4=CC(=CC=C4)Cl	IC50 = 55000 nM	Poor binder
T74312	Fms-like tyrosine kinase 3	B7N1WR	3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2S)-2,3-dihydroxypropyl]-4-methoxybenzamide	Investigative	57325479	C19H20ClNO4	361.8	COC1=C(C=C(C=C1)C(=O)NC[C@@H](CO)O)/C=C/C2=CC=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T74312	Fms-like tyrosine kinase 3	B84FCX	2-[(3,4-Dimethoxybenzoyl)amino]-4,5,6,7,8,9-hexahydrocycloocta[b]thiophene-3-carboxamide	Investigative	1742780	C20H24N2O4S	388.5	COC1=C(C=C(C=C1)C(=O)NC2=C(C3=C(S2)CCCCCC3)C(=O)N)OC	IC50 ~ 100000 nM	Poor binder
T74312	Fms-like tyrosine kinase 3	B9OH0G	7-[(4-Fluorophenyl)methyl]-2-methylsulfanyl-4-piperidin-1-ylpyrrolo[2,3-d]pyrimidine	Investigative	137641213	C19H21FN4S	356.5	CSC1=NC2=C(C=CN2CC3=CC=C(C=C3)F)C(=N1)N4CCCCC4	IC50 = 61000 nM	Poor binder
T74312	Fms-like tyrosine kinase 3	BBAF67	N-[2-(4-Chlorophenyl)ethyl]-7-[(4-fluorophenyl)methyl]-2-methylsulfanylpyrrolo[2,3-d]pyrimidin-4-amine	Investigative	137659733	C22H20ClFN4S	426.9	CSC1=NC(=C2C=CN(C2=N1)CC3=CC=C(C=C3)F)NCCC4=CC=C(C=C4)Cl	IC50 = 76000 nM	Poor binder
T74312	Fms-like tyrosine kinase 3	BD41VZ	7-[(4-Fluorophenyl)methyl]-2-methylsulfanyl-4-pyrrolidin-1-ylpyrrolo[2,3-d]pyrimidine	Investigative	137642749	C18H19FN4S	342.4	CSC1=NC2=C(C=CN2CC3=CC=C(C=C3)F)C(=N1)N4CCCC4	IC50 = 64000 nM	Poor binder
T74312	Fms-like tyrosine kinase 3	BJZ32R	4-[7-[(4-Fluorophenyl)methyl]-2-methylsulfanylpyrrolo[2,3-d]pyrimidin-4-yl]morpholine	Investigative	137659108	C18H19FN4OS	358.4	CSC1=NC2=C(C=CN2CC3=CC=C(C=C3)F)C(=N1)N4CCOCC4	IC50 = 61000 nM	Poor binder
T74312	Fms-like tyrosine kinase 3	BM8AQ9	N-Benzyl-7-[(4-fluorophenyl)methyl]-2-methylsulfanylpyrrolo[2,3-d]pyrimidin-4-amine	Investigative	137644946	C21H19FN4S	378.5	CSC1=NC(=C2C=CN(C2=N1)CC3=CC=C(C=C3)F)NCC4=CC=CC=C4	IC50 = 60000 nM	Poor binder
T74312	Fms-like tyrosine kinase 3	BMH52N	Propan-2-yl 2-[(E)-3-acetamidoprop-1-enyl]-6-hydroxy-4-methoxybenzoate	Investigative	118722026	C16H21NO5	307.34	CC(C)OC(=O)C1=C(C=C(C=C1O)OC)/C=C/CNC(=O)C	IC50 ~ 50000 nM	Poor binder
T74312	Fms-like tyrosine kinase 3	BQ9Y5W	2-[9-(4-Amino-3-methoxyphenyl)-6-oxo-5,11-dihydrobenzo[b][1,4]benzodiazepin-3-yl]-N-(4-morpholin-4-ylphenyl)acetamide	Investigative	44427518	C32H31N5O4	549.6	COC1=C(C=CC(=C1)C2=CC3=C(C=C2)C(=O)NC4=C(N3)C=CC(=C4)CC(=O)NC5=CC=C(C=C5)N6CCOCC6)N	IC50 ~ 50000 nM	Poor binder
T74312	Fms-like tyrosine kinase 3	BQYM49	7-(2-Chloro-2-phenylethyl)-2-methylsulfanyl-N-phenylpyrrolo[2,3-d]pyrimidin-4-amine	Investigative	137657483	C21H19ClN4S	394.9	CSC1=NC(=C2C=CN(C2=N1)CC(C3=CC=CC=C3)Cl)NC4=CC=CC=C4	IC50 = 72000 nM	Poor binder
T74312	Fms-like tyrosine kinase 3	BVI90B	Chembl4276946	Investigative	134611886	C12H11Cl2N3O	284.14	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T74312	Fms-like tyrosine kinase 3	BVN7G9	N-Benzyl-7-(2-chloro-2-phenylethyl)-2-methylsulfanylpyrrolo[2,3-d]pyrimidin-4-amine	Investigative	137655481	C22H21ClN4S	408.9	CSC1=NC(=C2C=CN(C2=N1)CC(C3=CC=CC=C3)Cl)NCC4=CC=CC=C4	IC50 = 68000 nM	Poor binder
T74312	Fms-like tyrosine kinase 3	D0W7TU	NSC-73306	Investigative	947057	C16H14N4O2S	326.4	.	IC50 ~ 50000 nM	Poor binder