TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T74500	Voltage-gated potassium channel Kv4.3	D01AXB	Duloxetine	Approved	60835	C18H19NOS	297.4	CNCC[C@@H](C1=CC=CS1)OC2=CC=CC3=CC=CC=C32	IC50 = 100000 nM	Poor binder
T74500	Voltage-gated potassium channel Kv4.3	D03IGH	Darunavir	Approved	213039	C27H37N3O7S	547.7	CC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)NC(=O)O[C@H]2CO[C@@H]3[C@H]2CCO3)O)S(=O)(=O)C4=CC=C(C=C4)N	IC50 = 100000 nM	Poor binder
T74500	Voltage-gated potassium channel Kv4.3	D0B3UJ	Paliperidone	Approved	115237	C23H27FN4O3	426.5	CC1=C(C(=O)N2CCCC(C2=N1)O)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F	IC50 = 63095.73 nM	Poor binder
T74500	Voltage-gated potassium channel Kv4.3	D0C9SY	Vardenafil	Approved	135400189	C23H32N6O4S	488.6	.	IC50 = 79432.82 nM	Poor binder
T74500	Voltage-gated potassium channel Kv4.3	D0L4YD	Solifenacin	Approved	154059	C23H26N2O2	362.5	C1CN2CCC1[C@H](C2)OC(=O)N3CCC4=CC=CC=C4[C@@H]3C5=CC=CC=C5	IC50 = 50118.72 nM	Poor binder
T74500	Voltage-gated potassium channel Kv4.3	D0Q5UQ	Exjade	Approved	214348	C21H15N3O4	373.4	.	IC50 = 50118.72 nM	Poor binder
T74500	Voltage-gated potassium channel Kv4.3	D0Z1UA	Nebivolol	Approved	71301	C22H25F2NO4	405.4	C1CC2=C(C=CC(=C2)F)OC1C(CNCC(C3CCC4=C(O3)C=CC(=C4)F)O)O	IC50 = 50118.72 nM	Poor binder
T74500	Voltage-gated potassium channel Kv4.3	D0YX2B	PMID28460551-Compound-2	Patented	5329102	C22H27FN4O2	398.5	CCN(CC)CCNC(=O)C1=C(NC(=C1C)/C=C\\2/C3=C(C=CC(=C3)F)NC2=O)C	IC50 = 50118.72 nM	Poor binder
T74500	Voltage-gated potassium channel Kv4.3	BI6KA8	6-[({1-[2-(7-Methoxy-2-oxoquinoxalin-1(2H)-yl)ethyl]piperidin-4-yl}amino)methyl]-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one	Investigative	15982534	C24H28N6O4	464.5	COC1=CC2=C(C=C1)N=CC(=O)N2CCN3CCC(CC3)NCC4=NC5=C(C=C4)OCC(=O)N5	IC50 ~ 100000 nM	Poor binder
T74500	Voltage-gated potassium channel Kv4.3	BMWG84	6H-Pyrimido[5,4-b][1,4]oxazin-7(8H)-one, 2-[[[trans-4-[(1R)-1-amino-2-(7-fluoro-2-oxo-1(2H)-quinoxalinyl)ethyl]cyclohexyl]amino]methyl]-	Investigative	46206000	C23H26FN7O3	467.5	C1CC(CCC1[C@H](CN2C3=C(C=CC(=C3)F)N=CC2=O)N)NCC4=NC=C5C(=N4)NC(=O)CO5	IC50 ~ 100000 nM	Poor binder