TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T75596	Methionine aminopeptidase 2	B0GY9J	4-[4-(4-Methoxyphenyl)piperazin-1-Yl]-2-(Pyridin-2-Yl)quinazoline	Investigative	58279815	C24H23N5O	397.5	COC1=CC=C(C=C1)N2CCN(CC2)C3=NC(=NC4=CC=CC=C43)C5=CC=CC=N5	IC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	B0TB7J	(2S,3R)-3-Amino-4-cyclohexyl-N-((S)-1,2-dimethyl-propyl)-2-hydroxy-butyramide	Investigative	44381857	C15H30N2O2	270.41	C[C@@H](C(C)C)NC(=O)[C@H]([C@@H](CC1CCCCC1)N)O	IC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	B1H2YM	Phenethyl-(2-pyridin-2-yl-quinazolin-4-yl)-amine	Investigative	937982	C21H18N4	326.4	C1=CC=C(C=C1)CCNC2=NC(=NC3=CC=CC=C32)C4=CC=CC=N4	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	B1N2GK	[(3S,6S)-7-Oxo-6-[[(E,2R,3R,4S,5R)-3,4,5-trihydroxy-2-methoxy-8-methylnon-6-enoyl]amino]azepan-3-yl] 12-methyltridecanoate	Investigative	10650951	C31H56N2O8	584.8	CC(C)CCCCCCCCCCC(=O)O[C@H]1CC[C@@H](C(=O)NC1)NC(=O)[C@@H]([C@@H]([C@H]([C@@H](/C=C/C(C)C)O)O)O)OC	IC50 ~ 50000 nM	Poor binder
T75596	Methionine aminopeptidase 2	B2T4WD	N-[(2S)-1-Oxo-3-phenyl-1-[4-(2-pyridin-2-ylquinolin-4-yl)piperazin-1-yl]propan-2-yl]acetamide	Investigative	73348797	C29H29N5O2	479.6	CC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N2CCN(CC2)C3=CC(=NC4=CC=CC=C43)C5=CC=CC=N5	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	B3O5YC	4-[4-(2-Pyridin-2-ylquinolin-4-yl)piperazin-1-yl]benzaldehyde	Investigative	73345797	C25H22N4O	394.5	C1CN(CCN1C2=CC=C(C=C2)C=O)C3=CC(=NC4=CC=CC=C43)C5=CC=CC=N5	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	B42TDI	(S)-2-((S)-3-Amino-4-cyclohexylmethylsulfanyl-2-hydroxy-butyrylamino)-propionic acid ethyl ester	Investigative	44381893	C16H30N2O4S	346.5	CCOC(=O)[C@H](C)NC(=O)C([C@@H](CSCC1CCCCC1)N)O	IC50 = 74000 nM	Poor binder
T75596	Methionine aminopeptidase 2	B43TGE	4-[4-(4-Nitrophenyl)piperazin-1-yl]-2-pyridin-2-ylquinoline	Investigative	73347281	C24H21N5O2	411.5	C1CN(CCN1C2=CC=C(C=C2)[N+](=O)[O-])C3=CC(=NC4=CC=CC=C43)C5=CC=CC=N5	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	B4DCG6	5,6-Disubstituted anthranilic acid sulfonamide, 9l	Investigative	23647772	C17H13BrFN3O5S	470.3	COC1=C(C=CC(=C1C(=O)O)NS(=O)(=O)C2=C(C=C(C=C2)F)Br)C3=CN=CN3	IC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	B5P6RT	(S)-2-Amino-hexanoic acid hydroxy-[(2-pyridin-2-yl-ethylcarbamoyl)-methyl]-amide	Investigative	10425401	C15H24N4O3	308.38	CCCC[C@@H](C(=O)N(CC(=O)NCCC1=CC=CC=N1)O)N	Ki = 164000 nM	Poor binder
T75596	Methionine aminopeptidase 2	B62BEY	4-[4-(3,4-Dichlorophenyl)piperazin-1-yl]-2-pyridin-2-ylquinoline	Investigative	73356423	C24H20Cl2N4	435.3	C1CN(CCN1C2=CC(=C(C=C2)Cl)Cl)C3=CC(=NC4=CC=CC=C43)C5=CC=CC=N5	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	B6G9YL	5,6-Disubstituted anthranilic acid sulfonamide, 9k	Investigative	23647771	C18H13BrFNO6S	470.3	COC1=C(C=CC(=C1C(=O)O)NS(=O)(=O)C2=C(C=C(C=C2)F)Br)C3=CC=CO3	IC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	B6J1KZ	2-[4-[4-(2-Pyridin-2-ylquinolin-4-yl)piperazin-1-yl]phenoxy]acetic acid	Investigative	73345795	C26H24N4O3	440.5	C1CN(CCN1C2=CC=C(C=C2)OCC(=O)O)C3=CC(=NC4=CC=CC=C43)C5=CC=CC=N5	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	B75MUH	Anthranilic Acid Sulfonamide, 10ap	Investigative	11663131	C26H37N3O4S	487.7	CCN(CC)CCCC(C)NC1=CC=CC=C1S(=O)(=O)NC2=C(C3=C(CCCC3)C=C2)C(=O)O	IC50 = 66000 nM	Poor binder
T75596	Methionine aminopeptidase 2	B76AFK	[(3S,6S)-1-Methyl-7-oxo-6-[[(E,2R,3R,4S,5R)-3,4,5-trihydroxy-2-methoxy-8-methylnon-6-enoyl]amino]azepan-3-yl] 12-methyltetradecanoate	Investigative	45267083	C33H60N2O8	612.8	CCC(C)CCCCCCCCCCC(=O)O[C@H]1CC[C@@H](C(=O)N(C1)C)NC(=O)[C@@H]([C@@H]([C@H]([C@@H](/C=C/C(C)C)O)O)O)OC	IC50 ~ 50000 nM	Poor binder
T75596	Methionine aminopeptidase 2	B82JAP	4-[4-(4-Methylphenyl)sulfonylpiperazin-1-yl]-2-pyridin-2-ylquinoline	Investigative	73348796	C25H24N4O2S	444.6	CC1=CC=C(C=C1)S(=O)(=O)N2CCN(CC2)C3=CC(=NC4=CC=CC=C43)C5=CC=CC=N5	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	B8W5NE	4-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-pyridin-2-ylquinoline	Investigative	73353356	C25H24N4O	396.5	COC1=CC=C(C=C1)N2CCN(CC2)C3=CC(=NC4=CC=CC=C43)C5=CC=CC=N5	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	B93QPI	(S)-2-((S)-3-Amino-4-benzylsulfanyl-2-hydroxy-butyrylamino)-propionic acid ethyl ester	Investigative	44381894	C16H24N2O4S	340.4	CCOC(=O)[C@H](C)NC(=O)C([C@@H](CSCC1=CC=CC=C1)N)O	IC50 = 51000 nM	Poor binder
T75596	Methionine aminopeptidase 2	B9GKO2	4-[4-(2-Pyridin-2-ylquinolin-4-yl)piperazin-1-yl]phenol	Investigative	73345796	C24H22N4O	382.5	C1CN(CCN1C2=CC=C(C=C2)O)C3=CC(=NC4=CC=CC=C43)C5=CC=CC=N5	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	BA4C9F	N-[5-[2-Oxo-2-[4-(2-pyridin-2-ylquinolin-4-yl)piperazin-1-yl]ethyl]-1,3-thiazol-2-yl]acetamide	Investigative	73353354	C25H24N6O2S	472.6	CC(=O)NC1=NC=C(S1)CC(=O)N2CCN(CC2)C3=CC(=NC4=CC=CC=C43)C5=CC=CC=N5	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	BAU10K	2-[(2,1,3-Benzothiadiazol-4-ylsulfonyl)amino]-5-bromobenzoic acid	Investigative	1042891	C13H8BrN3O4S2	414.3	C1=CC2=NSN=C2C(=C1)S(=O)(=O)NC3=C(C=C(C=C3)Br)C(=O)O	IC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	BEW12M	4-(Morpholin-4-yl)-2-(pyridin-2-yl)quinazoline	Investigative	661949	C17H16N4O	292.33	C1COCCN1C2=NC(=NC3=CC=CC=C32)C4=CC=CC=N4	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	BFRP69	1-[4-[4-(2-Pyridin-2-ylquinolin-4-yl)piperazin-1-yl]phenyl]ethanol	Investigative	73350374	C26H26N4O	410.5	CC(C1=CC=C(C=C1)N2CCN(CC2)C3=CC(=NC4=CC=CC=C43)C5=CC=CC=N5)O	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	BIWN42	Ethyl 2-[4-[4-(2-pyridin-2-ylquinolin-4-yl)piperazin-1-yl]phenoxy]acetate	Investigative	73356424	C28H28N4O3	468.5	CCOC(=O)COC1=CC=C(C=C1)N2CCN(CC2)C3=CC(=NC4=CC=CC=C43)C5=CC=CC=N5	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	BJ0FK3	5,6-Disubstituted anthranilic acid sulfonamide, 9g	Investigative	23647767	C16H16FNO5S	353.4	CC1=C(C=CC(=C1C(=O)O)NS(=O)(=O)C2=CC=C(C=C2)F)C(C)O	IC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	BJA97N	4-(4-Methylpiperazino)-2-(2-pyridyl)quinoline	Investigative	453063	C19H20N4	304.4	CN1CCN(CC1)C2=CC(=NC3=CC=CC=C32)C4=CC=CC=N4	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	BJT4B2	N'-[(2S,3R)-3-Amino-3-cyclohexyl-2-hydroxypropanoyl]naphthalene-2-carbohydrazide	Investigative	44382016	C20H25N3O3	355.4	C1CCC(CC1)[C@H]([C@@H](C(=O)NNC(=O)C2=CC3=CC=CC=C3C=C2)O)N	IC50 = 51000 nM	Poor binder
T75596	Methionine aminopeptidase 2	BK4XV1	1,4-Dihydroxy-3-methoxy-2-[2-methyl-3-(3-methyl-but-2-enyl)-oxiranyl]-cyclohexanecarbaldehyde	Investigative	11120072	C16H26O5	298.37	CC(=CC[C@@H]1[C@@](O1)(C)[C@H]2[C@@H]([C@@H](CC[C@@]2(C=O)O)O)OC)C	IC50 = 53600 nM	Poor binder
T75596	Methionine aminopeptidase 2	BK6D0Q	4-[4-(2-Pyridin-2-ylquinolin-4-yl)piperazin-1-yl]benzoic acid	Investigative	73345794	C25H22N4O2	410.5	C1CN(CCN1C2=CC=C(C=C2)C(=O)O)C3=CC(=NC4=CC=CC=C43)C5=CC=CC=N5	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	BMN5X9	4-[4-(4-Prop-2-enoxyphenyl)piperazin-1-yl]-2-pyridin-2-ylquinoline	Investigative	73345798	C27H26N4O	422.5	C=CCOC1=CC=C(C=C1)N2CCN(CC2)C3=CC(=NC4=CC=CC=C43)C5=CC=CC=N5	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	BOB28Y	4-Chloro-2-(pyridin-2-yl)quinazoline	Investigative	930716	C13H8ClN3	241.67	C1=CC=C2C(=C1)C(=NC(=N2)C3=CC=CC=N3)Cl	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	BP27VX	Ethyl 4-[4-(2-pyridin-2-ylquinolin-4-yl)piperazin-1-yl]benzoate	Investigative	73347280	C27H26N4O2	438.5	CCOC(=O)C1=CC=C(C=C1)N2CCN(CC2)C3=CC(=NC4=CC=CC=C43)C5=CC=CC=N5	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	BP5X4B	(S)-2-Amino-N-hydroxy-4-methylsulfanyl-N-[(2-pyridin-2-yl-ethylcarbamoyl)-methyl]-butyramide	Investigative	44378660	C14H22N4O3S	326.42	CSCC[C@@H](C(=O)N(CC(=O)NCCC1=CC=CC=N1)O)N	Ki = 91000 nM	Poor binder
T75596	Methionine aminopeptidase 2	BS2EW9	5,6-Disubstituted anthranilic acid sulfonamide, 9f	Investigative	23647766	C15H14FNO5S	339.3	CC1=C(C=CC(=C1C(=O)O)NS(=O)(=O)C2=CC=C(C=C2)F)CO	IC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	BT1AG7	4-Piperidin-1-yl-2-pyridin-2-ylquinoline	Investigative	2818423	C19H19N3	289.4	C1CCN(CC1)C2=CC(=NC3=CC=CC=C32)C4=CC=CC=N4	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	BUP9K7	Quinoline, 4-(4-morpholinyl)-2-(2-pyridinyl)-	Investigative	453059	C18H17N3O	291.3	C1COCCN1C2=CC(=NC3=CC=CC=C32)C4=CC=CC=N4	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	BWT76Z	(1S,5S)-5-(Hydroxymethyl)-1-methoxy-6-(6-methylhept-5-en-2-yl)bicyclo[3.1.0]hexan-2-one	Investigative	44416035	C16H26O3	266.38	CC(CCC=C(C)C)C1[C@]2([C@@]1(C(=O)CC2)OC)CO	IC50 = 57500 nM	Poor binder
T75596	Methionine aminopeptidase 2	BXI0P4	4-(Piperidin-1-yl)-2-(pyridin-2-yl)quinazoline	Investigative	935986	C18H18N4	290.4	C1CCN(CC1)C2=NC(=NC3=CC=CC=C32)C4=CC=CC=N4	EC50 ~ 100000 nM	Poor binder
T75596	Methionine aminopeptidase 2	BXTZ06	5,6-Disubstituted anthranilic acid sulfonamide, 17b	Investigative	23647777	C17H16FNO7S	397.4	CCC1=C(C(=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)F)C(=O)O)OCC(=O)O	IC50 ~ 100000 nM	Poor binder