TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T76059	FK506-binding protein 1A	B0BYN9	1-N-(2-Ethylphenyl)-2-N-(3-phenylpropyl)pyrrolidine-1,2-dicarboxamide	Investigative	44280959	C23H29N3O2	379.5	CCC1=CC=CC=C1NC(=O)N2CCCC2C(=O)NCCCC3=CC=CC=C3	Ki ~ 50000 nM	Poor binder
T76059	FK506-binding protein 1A	B12PGZ	Pyrrolidine-1,2-dicarboxylic acid 2-benzylamide 1-[(2-ethyl-phenyl)-amide]	Investigative	44281696	C21H25N3O2	351.4	CCC1=CC=CC=C1NC(=O)N2CCCC2C(=O)NCC3=CC=CC=C3	Ki ~ 50000 nM	Poor binder
T76059	FK506-binding protein 1A	B1DTQ6	4-[(R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxy-ethyl]-1-methyl-piperidine-2,6-dione	Investigative	10685294	C16H25NO4	295.37	C[C@H]1C[C@@H](C(=O)[C@@H](C1)[C@@H](CC2CC(=O)N(C(=O)C2)C)O)C	IC50 = 124100 nM	Poor binder
T76059	FK506-binding protein 1A	B29GBH	2-(3,4-Dimethoxyphenoxy)ethyl (2S)-1-(3,5-dichlorophenyl)sulfonylpiperidine-2-carboxylate	Investigative	57522800	C22H25Cl2NO7S	518.4	COC1=C(C=C(C=C1)OCCOC(=O)[C@@H]2CCCCN2S(=O)(=O)C3=CC(=CC(=C3)Cl)Cl)OC	IC50 ~ 100000 nM	Poor binder
T76059	FK506-binding protein 1A	B4B2RP	(1S,9R)-13-{2-[(1S,2R,5R)-1-Hydroxy-5-(2-methoxy-1-methyl-ethyl)-2-methyl-cyclohexyl]-2-oxo-acetyl}-5-hydroxymethyl-3,7-dioxa-13-aza-bicyclo[7.3.1]tridecane-2,8-dione	Investigative	44350709	C24H37NO9	483.6	C[C@@H]1CC[C@H](C[C@]1(C(=O)C(=O)N2[C@@H]3CCC[C@H]2C(=O)OCC(COC3=O)CO)O)C(C)COC	Ki ~ 50000 nM	Poor binder
T76059	FK506-binding protein 1A	B5B7YQ	1-N,2-N-Dibenzylpyrrolidine-1,2-dicarboxamide	Investigative	3219624	C20H23N3O2	337.4	C1CC(N(C1)C(=O)NCC2=CC=CC=C2)C(=O)NCC3=CC=CC=C3	Ki ~ 50000 nM	Poor binder
T76059	FK506-binding protein 1A	B6Z0BU	Timcodar	Investigative	9811664	C43H45ClN4O6	749.3	CN([C@@H](CC1=CC=C(C=C1)Cl)C(=O)N(CC2=CC=CC=C2)C(CCC3=CC=NC=C3)CCC4=CC=NC=C4)C(=O)C(=O)C5=CC(=C(C(=C5)OC)OC)OC	IC50 ~ 100000 nM	Poor binder
T76059	FK506-binding protein 1A	B7RQ6J	Pyrrolidine-1,2-dicarboxylic acid 2-butylamide 1-[(2-ethyl-phenyl)-amide]	Investigative	44281458	C18H27N3O2	317.4	CCCCNC(=O)C1CCCN1C(=O)NC2=CC=CC=C2CC	Ki ~ 50000 nM	Poor binder
T76059	FK506-binding protein 1A	B7UO1J	1-Benzyl-4-[(R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxo-cyclohexyl)-2-hydroxy-ethyl]-piperidine-2,6-dione	Investigative	10571272	C22H29NO4	371.5	C[C@H]1C[C@@H](C(=O)[C@@H](C1)[C@@H](CC2CC(=O)N(C(=O)C2)CC3=CC=CC=C3)O)C	IC50 = 116700 nM	Poor binder
T76059	FK506-binding protein 1A	B8DPN1	1-(Toluene-4-sulfonyl)-pyrrolidine-2-carboxylic acid benzylamide	Investigative	3154008	C19H22N2O3S	358.5	CC1=CC=C(C=C1)S(=O)(=O)N2CCCC2C(=O)NCC3=CC=CC=C3	Ki ~ 50000 nM	Poor binder
T76059	FK506-binding protein 1A	B8I3LR	Pyrrolidine-1,2-dicarboxylic acid 2-benzylamide 1-cyclohexylamide	Investigative	3219611	C19H27N3O2	329.4	C1CCC(CC1)NC(=O)N2CCCC2C(=O)NCC3=CC=CC=C3	Ki ~ 50000 nM	Poor binder
T76059	FK506-binding protein 1A	B8RA3F	1-Benzenesulfonyl-pyrrolidine-2-carboxylic acid butylamide	Investigative	44281206	C15H22N2O3S	310.4	CCCCNC(=O)C1CCCN1S(=O)(=O)C2=CC=CC=C2	Ki ~ 50000 nM	Poor binder
T76059	FK506-binding protein 1A	B92HYQ	Pyrrolidine-1,2-dicarboxylic acid 1-[(2-ethyl-phenyl)-amide] 2-(phenethyl-amide)	Investigative	44281114	C22H27N3O2	365.5	CCC1=CC=CC=C1NC(=O)N2CCCC2C(=O)NCCC3=CC=CC=C3	Ki ~ 50000 nM	Poor binder
T76059	FK506-binding protein 1A	B9T1PH	Pyrrolidine-1,2-dicarboxylic acid 1-benzylamide 2-butylamide	Investigative	44280958	C17H25N3O2	303.4	CCCCNC(=O)C1CCCN1C(=O)NCC2=CC=CC=C2	Ki ~ 50000 nM	Poor binder
T76059	FK506-binding protein 1A	BDYT98	(2S)-N-[(2R)-1-Amino-1-oxopropan-2-yl]-1-[(2S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxamide	Investigative	117967872	C26H39N3O6	489.6	C[C@H](C(=O)N)NC(=O)[C@@H]1CCCCN1C(=O)[C@@H](C2CCCCC2)C3=CC(=C(C(=C3)OC)OC)OC	Ki = 71100 nM	Poor binder
T76059	FK506-binding protein 1A	BE96SF	Methyl (4aS,8S)-2-benzyl-1-oxo-4,4a,5,6,7,8-hexahydro-3H-pyrido[1,2-c]pyrimidine-8-carboxylate	Investigative	10756782	C17H22N2O3	302.37	COC(=O)[C@@H]1CCC[C@@H]2N1C(=O)N(CC2)CC3=CC=CC=C3	Ki = 67000 nM	Poor binder
T76059	FK506-binding protein 1A	BG4WS2	(2R)-2-[[(2S)-1-[(2S)-2-Cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carbonyl]amino]pentanediamide	Investigative	117967801	C28H42N4O7	546.7	COC1=CC(=CC(=C1OC)OC)[C@H](C2CCCCC2)C(=O)N3CCCC[C@H]3C(=O)N[C@H](CCC(=O)N)C(=O)N	Ki = 120000 nM	Poor binder
T76059	FK506-binding protein 1A	BH2XF7	(2S)-N-(1-Carbamoylcyclopropyl)-1-[(2S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxamide	Investigative	117967885	C27H39N3O6	501.6	COC1=CC(=CC(=C1OC)OC)[C@H](C2CCCCC2)C(=O)N3CCCC[C@H]3C(=O)NC4(CC4)C(=O)N	Ki = 50300 nM	Poor binder
T76059	FK506-binding protein 1A	BHK4Y0	4-{4-[(R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxy-ethyl]-2,6-dioxo-piperidin-1-ylmethyl}-benzonitrile	Investigative	10834562	C23H28N2O4	396.5	C[C@H]1C[C@@H](C(=O)[C@@H](C1)[C@@H](CC2CC(=O)N(C(=O)C2)CC3=CC=C(C=C3)C#N)O)C	IC50 = 68200 nM	Poor binder
T76059	FK506-binding protein 1A	BI8N5C	1-(Octane-1-sulfonyl)-pyrrolidine-2-carboxylic acid phenethyl-amide	Investigative	44281259	C21H34N2O3S	394.6	CCCCCCCCS(=O)(=O)N1CCCC1C(=O)NCCC2=CC=CC=C2	Ki ~ 50000 nM	Poor binder
T76059	FK506-binding protein 1A	BL19CE	2-[3-[(1R)-1-[[(2S)-1-(3,5-Dichloro-4-hydroxyphenyl)sulfonylpiperidine-2-carbonyl]amino]-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid	Investigative	57523068	C31H34Cl2N2O9S	681.6	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)NC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC(=C(C(=C4)Cl)O)Cl)OC	IC50 ~ 100000 nM	Poor binder
T76059	FK506-binding protein 1A	BN5IF1	Pipecolate deriv., 12b	Investigative	11181229	C35H45N2O7P	636.7	C1CCN([C@@H](C1)C(=O)OC(CCCC2=CC=CC=C2)CCCC3=CC=CC=C3)C(=O)N[C@H](CC4=CC=CC=C4)COP(=O)(O)O	Ki = 137000 nM	Poor binder
T76059	FK506-binding protein 1A	BO8R1Z	CID 57522929	Investigative	57522929	C36H44Cl2N2O9S	751.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCCN3CCOCC3)OC(=O)[C@@H]4CCCCN4S(=O)(=O)C5=CC(=C(C(=C5)Cl)OC)Cl)OC	IC50 ~ 50000 nM	Poor binder
T76059	FK506-binding protein 1A	BON0E9	(2S)-N-[(2S)-1-Amino-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-1-[(2S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxamide	Investigative	117967909	C29H41N5O6	555.7	COC1=CC(=CC(=C1OC)OC)[C@H](C2CCCCC2)C(=O)N3CCCC[C@H]3C(=O)N[C@@H](CC4=CN=CN4)C(=O)N	Ki = 101000 nM	Poor binder
T76059	FK506-binding protein 1A	BS0U6Q	1-Phenylmethanesulfonyl-piperidine-2-carboxylic acid butylamide	Investigative	44281207	C17H26N2O3S	338.5	CCCCNC(=O)C1CCCCN1S(=O)(=O)CC2=CC=CC=C2	Ki ~ 50000 nM	Poor binder
T76059	FK506-binding protein 1A	BT3G6R	Pyrrolidine-1,2-dicarboxylic acid 2-butylamide 1-cyclohexylamide	Investigative	3221232	C16H29N3O2	295.42	CCCCNC(=O)C1CCCN1C(=O)NC2CCCCC2	Ki ~ 50000 nM	Poor binder
T76059	FK506-binding protein 1A	BTKO61	CID 57522803	Investigative	57522803	C36H43N3O8S2	709.9	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCCN3CCOCC3)OC(=O)[C@@H]4CCCCN4S(=O)(=O)C5=CC6=C(C=C5)N=CS6)OC	IC50 ~ 50000 nM	Poor binder
T76059	FK506-binding protein 1A	BV37HF	Pyrrolidine-1,2-dicarboxylic acid 1-cyclohexylamide 2-(phenethyl-amide)	Investigative	44281293	C20H29N3O2	343.5	C1CCC(CC1)NC(=O)N2CCCC2C(=O)NCCC3=CC=CC=C3	Ki ~ 50000 nM	Poor binder
T76059	FK506-binding protein 1A	BV57KG	1-(Octane-1-sulfonyl)-pyrrolidine-2-carboxylic acid benzylamide	Investigative	44281260	C20H32N2O3S	380.5	CCCCCCCCS(=O)(=O)N1CCCC1C(=O)NCC2=CC=CC=C2	Ki ~ 50000 nM	Poor binder
T76059	FK506-binding protein 1A	BV58LY	(2S)-N-[(2S)-1-Amino-1-oxobutan-2-yl]-1-[(2S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxamide	Investigative	117967822	C27H41N3O6	503.6	CC[C@@H](C(=O)N)NC(=O)[C@@H]1CCCCN1C(=O)[C@@H](C2CCCCC2)C3=CC(=C(C(=C3)OC)OC)OC	Ki = 51900 nM	Poor binder
T76059	FK506-binding protein 1A	BV84RF	1-(Toluene-4-sulfonyl)-pyrrolidine-2-carboxylic acid butylamide	Investigative	44281153	C16H24N2O3S	324.4	CCCCNC(=O)C1CCCN1S(=O)(=O)C2=CC=C(C=C2)C	Ki ~ 50000 nM	Poor binder
T76059	FK506-binding protein 1A	BW7G5J	Methyl (4aS,8S)-1-oxo-2-propyl-4,4a,5,6,7,8-hexahydro-3H-pyrido[1,2-c]pyrimidine-8-carboxylate	Investigative	10587060	C13H22N2O3	254.33	CCCN1CC[C@@H]2CCC[C@H](N2C1=O)C(=O)OC	Ki = 83000 nM	Poor binder
T76059	FK506-binding protein 1A	BZ74OD	1-((E)-2-Phenyl-ethenesulfonyl)-pyrrolidine-2-carboxylic acid benzylamide	Investigative	44281249	C20H22N2O3S	370.5	C1CC(N(C1)S(=O)(=O)/C=C/C2=CC=CC=C2)C(=O)NCC3=CC=CC=C3	Ki ~ 50000 nM	Poor binder
T76059	FK506-binding protein 1A	BZTN10	CID 57522802	Investigative	57522802	C35H42Cl2N2O8S	721.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCCN3CCOCC3)OC(=O)[C@@H]4CCCCN4S(=O)(=O)C5=CC(=CC(=C5)Cl)Cl)OC	IC50 ~ 50000 nM	Poor binder