TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T76910	Glycogen synthase kinase-3 alpha	B06LUG	4-Arylmaleimide deriv. 6-t	Investigative	6539495	C17H11N3O6	353.28	C1=CC(=CC(=C1)[N+](=O)[O-])C2=C(C(=O)NC2=O)NC3=CC=CC(=C3)C(=O)O	IC50 = 79000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	B0DPV3	4-Arylmaleimide deriv. 6-u	Investigative	6539496	C17H11ClN2O4	342.7	C1=CC(=CC(=C1)NC2=C(C(=O)NC2=O)C3=CC=C(C=C3)Cl)C(=O)O	IC50 = 186000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	B0F5XW	3,6-Diamino-2-(3-chlorobenzoyl)-4-(2-iodophenyl)thieno[2,3-b]pyridine-5-carbonitrile	Investigative	51347682	C21H12ClIN4OS	530.8	C1=CC=C(C(=C1)C2=C(C(=NC3=C2C(=C(S3)C(=O)C4=CC(=CC=C4)Cl)N)N)C#N)I	IC50 ~ 100000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	B0XKW1	1-[(4-Methoxyphenyl)methyl]-3-[6-(2H-tetrazol-5-yl)-1,3-benzothiazol-2-yl]urea	Investigative	53388145	C17H15N7O2S	381.4	COC1=CC=C(C=C1)CNC(=O)NC2=NC3=C(S2)C=C(C=C3)C4=NNN=N4	IC50 = 130000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	B27PBJ	(4S,6E)-18-Hydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),6,15,17-tetraene-2,8-dione	Investigative	49842778	C19H24O5	332.4	C[C@H]1C/C=C/C(=O)CCCCCC2=C(C(=CC(=C2)OC)O)C(=O)O1	IC50 ~ 100000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	B28WPL	3-[(3-Chloro-4-Hydroxyphenyl)amino]-4-(3-Chlorophenyl)-1h-Pyrrole-2,5-Dione	Investigative	6539478	C16H10Cl2N2O3	349.2	C1=CC(=CC(=C1)Cl)C2=C(C(=O)NC2=O)NC3=CC(=C(C=C3)O)Cl	IC50 = 94000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	B2CQ0O	4-Arylmaleimide deriv. 6ee	Investigative	6539504	C17H13ClN2O2S	344.8	CSC1=CC=C(C=C1)NC2=C(C(=O)NC2=O)C3=CC=CC=C3Cl	IC50 = 161000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	B2D3CB	4-Arylmaleimide deriv. 6x	Investigative	6539474	C16H11N3O5	325.27	C1=CC(=CC(=C1)[N+](=O)[O-])C2=C(C(=O)NC2=O)NC3=CC=C(C=C3)O	IC50 = 123000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	B2UY3C	4-Arylmaleimide deriv. 6l	Investigative	6539462	C16H10ClN3O4	343.72	C1=CC(=CC(=C1)[N+](=O)[O-])C2=C(C(=O)NC2=O)NC3=CC(=CC=C3)Cl	IC50 = 70000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	B3A6GI	4-Arylmaleimide deriv. 6-r	Investigative	6539493	C17H11ClN2O4	342.7	C1=CC(=CC(=C1)Cl)C2=C(C(=O)NC2=O)NC3=CC=CC(=C3)C(=O)O	IC50 = 134000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	B3H7QL	4-Arylmaleimide deriv. 6h	Investigative	6539458	C16H10Cl2N2O2	333.2	C1=CC=C(C(=C1)C2=C(C(=O)NC2=O)NC3=CC(=CC=C3)Cl)Cl	IC50 = 195000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	B3MCI2	4-Arylmaleimide deriv. 6j	Investigative	6539460	C16H10ClN3O4	343.72	C1=CC=C(C(=C1)C2=C(C(=O)NC2=O)NC3=CC(=CC=C3)Cl)[N+](=O)[O-]	IC50 = 104000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	B4HU5D	Cyclapolin 9	Investigative	2779952	C9H4F3N3O4S	307.21	C1=C(C=C(C2=C1[N+](=C(S2)C(=O)N)[O-])[N+](=O)[O-])C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	B5JKY1	4-Arylmaleimide deriv. 6-s	Investigative	6539494	C18H14N2O5	338.3	COC1=CC=CC(=C1)C2=C(C(=O)NC2=O)NC3=CC=CC(=C3)C(=O)O	IC50 = 195000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	B6HQ0G	4-Arylmaleimide deriv. 6II	Investigative	6539508	C17H13N3O4S	355.4	CSC1=CC=C(C=C1)NC2=C(C(=O)NC2=O)C3=CC(=CC=C3)[N+](=O)[O-]	IC50 = 152000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	B6Q2VF	4-Arylmaleimide deriv. 6-m	Investigative	6539488	C16H9Cl3N2O3	383.6	C1=CC(=CC=C1C2=C(C(=O)NC2=O)NC3=CC(=C(C(=C3)Cl)O)Cl)Cl	IC50 = 91000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	B7C1JT	3,6-Diamino-2-(3-chlorobenzoyl)-4-(2-chlorophenyl)thieno[2,3-b]pyridine-5-carbonitrile	Investigative	51039273	C21H12Cl2N4OS	439.3	C1=CC=C(C(=C1)C2=C(C(=NC3=C2C(=C(S3)C(=O)C4=CC(=CC=C4)Cl)N)N)C#N)Cl	IC50 ~ 100000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	B9G3HB	4-Arylmaleimide deriv. 6aa	Investigative	6539501	C18H13ClN2O5	372.8	COC1=CC=CC(=C1)C2=C(C(=O)NC2=O)NC3=CC(=C(C=C3)Cl)C(=O)O	IC50 = 85000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	B9TOA2	4-Arylmaleimide deriv. 6-j	Investigative	6539485	C16H9Cl3N2O3	383.6	C1=CC(=CC(=C1)Cl)C2=C(C(=O)NC2=O)NC3=CC(=C(C(=C3)Cl)O)Cl	IC50 = 58000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	B9TY2E	4-Arylmaleimide deriv. 6-x	Investigative	6539499	C17H10Cl2N2O4	377.2	C1=CC=C(C(=C1)C2=C(C(=O)NC2=O)NC3=CC(=C(C=C3)Cl)C(=O)O)Cl	IC50 = 74000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BC4J9U	4-Arylmaleimide deriv. 6cc	Investigative	6539502	C17H10Cl2N2O4	377.2	C1=CC(=CC=C1C2=C(C(=O)NC2=O)NC3=CC(=C(C=C3)Cl)C(=O)O)Cl	IC50 = 109000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BC6DG1	4-Arylmaleimide deriv. 6-a	Investigative	6539477	C17H13ClN2O4	344.7	COC1=CC=CC=C1C2=C(C(=O)NC2=O)NC3=CC(=C(C=C3)O)Cl	IC50 = 139000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BCH1I3	4-Arylmaleimide deriv. 6z	Investigative	6539476	C16H10Cl2N2O3	349.2	C1=CC=C(C(=C1)C2=C(C(=O)NC2=O)NC3=CC(=C(C=C3)O)Cl)Cl	IC50 = 152000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BCU6V2	4-Arylmaleimide deriv. 6d	Investigative	6539454	C16H11N3O4	309.28	C1=CC=C(C=C1)NC2=C(C(=O)NC2=O)C3=CC(=CC=C3)[N+](=O)[O-]	IC50 = 141000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BGC3X2	3,6-Diamino-2-(4-chlorobenzoyl)-4-(2-iodophenyl)thieno[2,3-b]pyridine-5-carbonitrile	Investigative	1729742	C21H12ClIN4OS	530.8	C1=CC=C(C(=C1)C2=C(C(=NC3=C2C(=C(S3)C(=O)C4=CC=C(C=C4)Cl)N)N)C#N)I	IC50 ~ 100000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BI2O9K	4-Arylmaleimide deriv. 6-k	Investigative	6539486	C17H12Cl2N2O4	379.2	COC1=CC=CC(=C1)C2=C(C(=O)NC2=O)NC3=CC(=C(C(=C3)Cl)O)Cl	IC50 = 142000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BIK90Z	4-Arylmaleimide deriv. 6-f	Investigative	6539481	C16H10Cl2N2O3	349.2	C1=CC=C(C=C1)C2=C(C(=O)NC2=O)NC3=CC(=C(C(=C3)Cl)O)Cl	IC50 = 149000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BJVU06	4-Arylmaleimide deriv. 6-i	Investigative	6539484	C16H9Cl2N3O5	394.2	C1=CC=C(C(=C1)C2=C(C(=O)NC2=O)NC3=CC(=C(C(=C3)Cl)O)Cl)[N+](=O)[O-]	IC50 = 52000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BK16LG	4-Arylmaleimide deriv. 6-g	Investigative	6539482	C16H9Cl3N2O3	383.6	C1=CC=C(C(=C1)C2=C(C(=O)NC2=O)NC3=CC(=C(C(=C3)Cl)O)Cl)Cl	IC50 = 93000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BK6H3X	4-Arylmaleimide deriv. 6-w	Investigative	6539498	C17H11ClN2O4	342.7	C1=CC=C(C=C1)C2=C(C(=O)NC2=O)NC3=CC(=C(C=C3)Cl)C(=O)O	IC50 = 143000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BLH79K	4-Arylmaleimide deriv. 6i	Investigative	6539459	C17H13ClN2O3	328.7	COC1=CC=CC=C1C2=C(C(=O)NC2=O)NC3=CC(=CC=C3)Cl	IC50 = 114000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BM3VZ2	4-Arylmaleimide deriv. 6-o	Investigative	6539490	C16H9Cl2N3O5	394.2	C1=CC(=CC=C1C2=C(C(=O)NC2=O)NC3=CC(=C(C(=C3)Cl)O)Cl)[N+](=O)[O-]	IC50 = 71000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BN24SQ	2-Benzothiazolecarboxamide, 7-nitro-5-[(trifluoromethyl)thio]-, 3-oxide	Investigative	9548013	C9H4F3N3O4S2	339.3	C1=C(C=C(C2=C1[N+](=C(S2)C(=O)N)[O-])[N+](=O)[O-])SC(F)(F)F	IC50 ~ 100000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BPR0M1	3,6-Diamino-2-benzoyl-4-(2-methoxyphenyl)thieno[2,3-b]pyridine-5-carbonitrile	Investigative	51347384	C22H16N4O2S	400.5	COC1=CC=CC=C1C2=C(C(=NC3=C2C(=C(S3)C(=O)C4=CC=CC=C4)N)N)C#N	IC50 ~ 100000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BQ1AM8	(4S,6E,12E)-18-Hydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),6,12,15,17-pentaene-2,8-dione	Investigative	49842666	C19H22O5	330.4	C[C@H]1C/C=C/C(=O)CCC/C=C/C2=C(C(=CC(=C2)OC)O)C(=O)O1	IC50 ~ 100000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BU3PQ2	4-Arylmaleimide deriv. 6-h	Investigative	6539483	C17H12Cl2N2O4	379.2	COC1=CC=CC=C1C2=C(C(=O)NC2=O)NC3=CC(=C(C(=C3)Cl)O)Cl	IC50 = 82000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BU4RA8	4-Arylmaleimide deriv. 6-e	Investigative	6539480	C16H10Cl2N2O3	349.2	C1=CC(=CC=C1C2=C(C(=O)NC2=O)NC3=CC(=C(C=C3)O)Cl)Cl	IC50 = 173000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BUAH69	4-Arylmaleimide deriv. 6-q	Investigative	6539492	C17H11ClN2O4	342.7	C1=CC=C(C(=C1)C2=C(C(=O)NC2=O)NC3=CC=CC(=C3)C(=O)O)Cl	IC50 = 136000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BVRE50	4-Arylmaleimide deriv. 6ff	Investigative	6539505	C18H16N2O3S	340.4	COC1=CC=CC=C1C2=C(C(=O)NC2=O)NC3=CC=C(C=C3)SC	IC50 = 110000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BWF26K	3,6-Diamino-4-(2-bromophenyl)-2-(3-chlorobenzoyl)thieno[2,3-b]pyridine-5-carbonitrile	Investigative	51347839	C21H12BrClN4OS	483.8	C1=CC=C(C(=C1)C2=C(C(=NC3=C2C(=C(S3)C(=O)C4=CC(=CC=C4)Cl)N)N)C#N)Br	IC50 ~ 100000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BWY23Z	4-Arylmaleimide deriv. 8c	Investigative	6539518	C18H13N3O4	335.3	C1CN(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CC=CC=C4[N+](=O)[O-]	IC50 = 131000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BY72FT	4-Arylmaleimide deriv. 6-d	Investigative	6539479	C16H10ClN3O5	359.72	C1=CC(=CC(=C1)[N+](=O)[O-])C2=C(C(=O)NC2=O)NC3=CC(=C(C=C3)O)Cl	IC50 = 59000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BYGI34	4-Arylmaleimide deriv. 6-n	Investigative	6539489	C17H12Cl2N2O4	379.2	COC1=CC=C(C=C1)C2=C(C(=O)NC2=O)NC3=CC(=C(C(=C3)Cl)O)Cl	IC50 = 83000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	BZ6F9J	4-Arylmaleimide deriv. 8e	Investigative	6539520	C18H13N3O4	335.3	C1CN(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CC(=CC=C4)[N+](=O)[O-]	IC50 = 161000 nM	Poor binder
T76910	Glycogen synthase kinase-3 alpha	D02OPH	I-5	Investigative	448008	C17H10Cl2N2O4	377.2	C1=CC(=CC(=C1)Cl)C2=C(C(=O)NC2=O)NC3=CC(=C(C=C3)Cl)C(=O)O	IC50 = 76000 nM	Poor binder