TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T77181	Ubiquitin thioesterase L3	D03GET	Menadione	Approved	4055	C11H8O2	172.18	CC1=CC(=O)C2=CC=CC=C2C1=O	IC50 = 71000 nM	Poor binder
T77181	Ubiquitin thioesterase L3	B82XVC	3-Hydroxy-5-(4-methoxyphenyl)-1-(1,3,4-thiadiazol-2-yl)-4-(thiophen-2-ylcarbonyl)-1,5-dihydro-2H-pyrrol-2-one	Investigative	2891549	C18H13N3O4S2	399.4	COC1=CC=C(C=C1)C2C(=C(C(=O)N2C3=NN=CS3)O)C(=O)C4=CC=CS4	IC50 = 154000 nM	Poor binder
T77181	Ubiquitin thioesterase L3	B89EAT	(4E)-5-(4-Fluorophenyl)-4-[hydroxy(5-methylfuran-2-yl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione	Investigative	2913480	C22H17FN2O4	392.4	CC1=CC=C(O1)C(=O)C2=C(C(=O)N(C2C3=CC=C(C=C3)F)CC4=CN=CC=C4)O	IC50 = 123000 nM	Poor binder
T77181	Ubiquitin thioesterase L3	BMQN01	1-Benzyl-3-hydroxy-4-(5-methyl-2-furoyl)-5-(3-pyridinyl)-1,5-dihydro-2H-pyrrol-2-one	Investigative	2941245	C22H18N2O4	374.4	CC1=CC=C(O1)C(=O)C2=C(C(=O)N(C2C3=CN=CC=C3)CC4=CC=CC=C4)O	IC50 = 103000 nM	Poor binder
T77181	Ubiquitin thioesterase L3	D0N6BC	LDN-91946	Investigative	950368	C15H10N2O4S	314.3	C1=CC=C(C=C1)C(=O)C2=C(C3=C(S2)NC(=O)C(=C3)C(=O)O)N	Ki = 100000 nM	Poor binder