TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T78205 Long transient receptor potential channel 2 D00HGB Niflumic Acid Approved 4488 C13H9F3N2O2 282.22 C1=CC(=CC(=C1)NC2=C(C=CC=N2)C(=O)O)C(F)(F)F IC50 = 149000 nM Poor binder T78205 Long transient receptor potential channel 2 D05FTJ Mefenamic acid Approved 4044 C15H15NO2 241.28 CC1=C(C(=CC=C1)NC2=CC=CC=C2C(=O)O)C IC50 = 124000 nM Poor binder T78205 Long transient receptor potential channel 2 D06ACW Adenosine monophosphate Approved 6083 C10H14N5O7P 347.22 C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)N IC50 = 70000 nM Poor binder T78205 Long transient receptor potential channel 2 D0B2WJ Flufenamic Acid Approved 3371 C14H10F3NO2 281.23 C1=CC=C(C(=C1)C(=O)O)NC2=CC=CC(=C2)C(F)(F)F IC50 = 70000 nM Poor binder T78205 Long transient receptor potential channel 2 B24YZJ 9-(4-Hydroxybutyl)adenine 5'-diphosphoribose Investigative 76314001 C14H23N5O11P2 499.31 C1=NC(=C2C(=N1)N(C=N2)CCCCOP(=O)(O)OP(=O)(O)OC[C@@H]3[C@H]([C@H](C(O3)O)O)O)N IC50 = 100000 nM Poor binder T78205 Long transient receptor potential channel 2 B35FOA Salicyl-AMS Investigative 636430 C17H18N6O8S 466.4 C1=CC=C(C(=C1)C(=O)NS(=O)(=O)OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O)O IC50 = 100000 nM Poor binder T78205 Long transient receptor potential channel 2 B3HS1R ADP-D-ribose Investigative 33576 C15H23N5O14P2 559.32 C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)OC[C@@H]4[C@H]([C@H](C(O4)O)O)O)O)O)N EC50 = 100000 nM Poor binder T78205 Long transient receptor potential channel 2 B8RT6Y 8-(3-Thiophenyl)adenosine 5'-diphosphoribose Investigative 76332138 C19H25N5O14P2S 641.4 C1=CSC=C1C2=NC3=C(N=CN=C3N2[C@H]4[C@@H]([C@@H]([C@H](O4)COP(=O)(O)OP(=O)(O)OC[C@@H]5[C@H]([C@H](C(O5)O)O)O)O)O)N IC50 = 51000 nM Poor binder T78205 Long transient receptor potential channel 2 BW9U3X N-(3-Methylphenyl)anthranilic acid Investigative 85472 C14H13NO2 227.26 CC1=CC(=CC=C1)NC2=CC=CC=C2C(=O)O IC50 = 76000 nM Poor binder T78205 Long transient receptor potential channel 2 BYFM87 8-(4-(2-Aminopropanoic acid)phenyl)adenosine 5'-monophosphate Investigative 76321279 C19H23N6O9P 510.4 C1=CC(=CC=C1CC(C(=O)O)N)C2=NC3=C(N=CN=C3N2[C@H]4[C@@H]([C@@H]([C@H](O4)COP(=O)(O)O)O)O)N IC50 = 100000 nM Poor binder