TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T80896	Estrogen receptor beta	D0D1SG	Prednisolone	Approved	5755	C21H28O5	360.4	C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)CCC4=CC(=O)C=C[C@]34C)O	IC50 ~ 100000 nM	Poor binder
T80896	Estrogen receptor beta	D0SZ1G	AZD9567	Phase 1	121248172	C27H28F2N4O3	494.5	CC(C)[C@@H]([C@@H](C1=CC=CC=C1)OC2=CC3=C(C=C2)N(N=C3)C4=CN(C(=O)C=C4)C)NC(=O)C(C)(F)F	IC50 ~ 100000 nM	Poor binder
T80896	Estrogen receptor beta	B3XA7L	(3S,4R)-1,3-Bis(4-hydroxyphenyl)-4-(3,4,5-trimethoxyphenyl)azetidin-2-one	Investigative	118724554	C24H23NO6	421.4	COC1=CC(=CC(=C1OC)OC)[C@H]2[C@@H](C(=O)N2C3=CC=C(C=C3)O)C4=CC=C(C=C4)O	IC50 = 144000 nM	Poor binder
T80896	Estrogen receptor beta	B4EG5X	Benzyl-(2-isobutylamino-6-styryl-pyrimidin-4-yl)-carbamic acid tert-butyl ester	Investigative	25131898	C28H34N4O2	458.6	CC(C)CNC1=NC(=CC(=N1)N(CC2=CC=CC=C2)C(=O)OC(C)(C)C)/C=C/C3=CC=CC=C3	Ki = 132000 nM	Poor binder
T80896	Estrogen receptor beta	B5GTR6	5-Hydroxy-3-(4-hydroxyphenyl)-7-methoxy-2-sulfanylidene-1H-quinazolin-4-one	Investigative	11565917	C15H12N2O4S	316.3	COC1=CC2=C(C(=C1)O)C(=O)N(C(=S)N2)C3=CC=C(C=C3)O	IC50 = 72848 nM	Poor binder
T80896	Estrogen receptor beta	B5WPY4	Emodin-8-glucoside	Investigative	99649	C21H20O10	432.4	CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O	IC50 = 62000 nM	Poor binder
T80896	Estrogen receptor beta	B64QOG	Chembl4293810	Investigative	124088406	C14H20O2	220.31	C1CC(CCC(C1)C2=CC=C(C=C2)O)CO	EC50 ~ 100000 nM	Poor binder
T80896	Estrogen receptor beta	B7A9SV	(+)-(2R)Kazinol I	Investigative	46871916	C25H30O4	394.5	CC(=CCC1=C(C(=C(C=C1[C@H]2CCC3=C(O2)C=C(C=C3)O)O)O)CC=C(C)C)C	IC50 = 96000 nM	Poor binder
T80896	Estrogen receptor beta	B82CLA	7-Hydroxy-3-(4-hydroxyphenyl)-4-oxo-3,4-dihydroquinazoline-5-carbonitrile	Investigative	11572694	C15H9N3O3	279.25	C1=CC(=CC=C1N2C=NC3=CC(=CC(=C3C2=O)C#N)O)O	IC50 = 73677 nM	Poor binder
T80896	Estrogen receptor beta	B9AMF7	2-(1-Naphthylsulfonyl)-1,2,3,4-tetrahydro-6-isoquinolinol	Investigative	52937308	C19H17NO3S	339.4	C1CN(CC2=C1C=C(C=C2)O)S(=O)(=O)C3=CC=CC4=CC=CC=C43	EC50 = 60000 nM	Poor binder
T80896	Estrogen receptor beta	BD35TU	N'-[(E)-(5-Bromo-2-hydroxyphenyl)methylidene]-3-hydroxynaphthalene-2-carbohydrazide	Investigative	135459005	C18H13BrN2O3	385.2	C1=CC=C2C=C(C(=CC2=C1)C(=O)N/N=C/C3=C(C=CC(=C3)Br)O)O	IC50 ~ 100000 nM	Poor binder
T80896	Estrogen receptor beta	BG0EN4	3-[(3R,3Ar,6S,7S,8R,9aS,9bS)-8-hydroxy-3-[(E,2R)-7-methoxy-6-methyl-7-oxohept-5-en-2-yl]-3a,6,9b-trimethyl-7-prop-1-en-2-yl-1,2,3,4,7,8,9,9a-octahydrocyclopenta[a]naphthalen-6-yl]propanoic acid	Investigative	73347354	C31H48O5	500.7	C[C@H](CC/C=C(\\C)/C(=O)OC)[C@H]1CC[C@@]2([C@@]1(CC=C3[C@H]2C[C@H]([C@H]([C@]3(C)CCC(=O)O)C(=C)C)O)C)C	EC50 = 72400 nM	Poor binder
T80896	Estrogen receptor beta	BL7OI3	(4R)-1,4-Bis(4-hydroxyphenyl)azetidin-2-one	Investigative	118724546	C15H13NO3	255.27	C1[C@@H](N(C1=O)C2=CC=C(C=C2)O)C3=CC=C(C=C3)O	IC50 = 56000 nM	Poor binder
T80896	Estrogen receptor beta	BLYA84	Sulfamic acid 2-adamantan-2-ylidenemethyl-benzooxazol-6-yl ester	Investigative	9820272	C18H20N2O4S	360.4	C1C2CC3CC1CC(C2)C3=CC4=NC5=C(O4)C=C(C=C5)OS(=O)(=O)N	EC50 ~ 100000 nM	Poor binder
T80896	Estrogen receptor beta	BN6TX5	7-Hydroxy-2-naphthyl 3-methylbenzoate	Investigative	837853	C18H14O3	278.3	CC1=CC(=CC=C1)C(=O)OC2=CC3=C(C=CC(=C3)O)C=C2	IC50 ~ 100000 nM	Poor binder
T80896	Estrogen receptor beta	BY1OB7	7-Hydroxy-2-naphthyl 2-methoxybenzoate	Investigative	837838	C18H14O4	294.3	COC1=CC=CC=C1C(=O)OC2=CC3=C(C=CC(=C3)O)C=C2	IC50 ~ 100000 nM	Poor binder
T80896	Estrogen receptor beta	BYB2K9	5,7-Dihydroxy-3-(6-oxo-1H-pyridin-3-yl)quinazolin-4-one	Investigative	11572578	C13H9N3O4	271.23	C1=CC(=O)NC=C1N2C=NC3=C(C2=O)C(=CC(=C3)O)O	IC50 = 51696 nM	Poor binder
T80896	Estrogen receptor beta	BZ8FY4	N'-[(E)-(4-Hydroxy-3,5-dimethoxyphenyl)methylidene]naphtho[2,1-b]furan-2-carbohydrazide	Investigative	135571931	C22H18N2O5	390.4	COC1=CC(=CC(=C1O)OC)/C=N/NC(=O)C2=CC3=C(O2)C=CC4=CC=CC=C43	IC50 ~ 100000 nM	Poor binder