TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T81900	Insulin-degrading enzyme	B6FY5W	2-[Benzyl-[2-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]acetic acid	Investigative	67421743	C21H24N2O5	384.4	COC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CN(CC2=CC=CC=C2)CC(=O)O	IC50 ~ 100000 nM	Poor binder
T81900	Insulin-degrading enzyme	BB65TF	2-[Benzoyl-[2-[[(2S)-3-(1H-imidazol-5-yl)-1-methoxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]acetic acid	Investigative	53378322	C18H20N4O6	388.4	COC(=O)[C@H](CC1=CN=CN1)NC(=O)CN(CC(=O)O)C(=O)C2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T81900	Insulin-degrading enzyme	BN2H4K	US9243038, 1 (cis olefin)	Investigative	124037306	C26H41N7O7	563.6	C1CCC(CC1)C[C@H]2C(=O)NCC(=O)NCCCC[C@H](NC(=O)/C=C/C(=O)N[C@H](C(=O)N2)CCC(=O)N)C(=O)N	IC50 ~ 100000 nM	Poor binder
T81900	Insulin-degrading enzyme	BN4TI7	Methyl 2-[[2-[[(2S)-3-(1H-imidazol-5-yl)-1-(methylamino)-1-oxopropan-2-yl]amino]-2-oxoethyl]-(3-phenylpropyl)amino]acetate	Investigative	67422530	C21H29N5O4	415.5	CNC(=O)[C@H](CC1=CN=CN1)NC(=O)CN(CCCC2=CC=CC=C2)CC(=O)OC	IC50 ~ 100000 nM	Poor binder
T81900	Insulin-degrading enzyme	BP2UG9	US9243038, 4b (trans olefin)	Investigative	124037307	C32H52N6O7	632.8	C1CCC(CC1)C[C@H]2[C@@H](CC(=O)N[C@H](C(=O)NCC(=O)NCCCC[C@H](NC(=O)/C=C/C(=O)N2)C(=O)N)CC3CCCCC3)O	IC50 ~ 100000 nM	Poor binder