TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T83813	5-HT 2C receptor	D0Q1ER	CGS-12066B	Terminated	2689	C17H17F3N4	334.34	CN1CCN(CC1)C2=NC3=C(C=CC(=C3)C(F)(F)F)N4C2=CC=C4	IC50 = 97723.72 nM	Poor binder
T83813	5-HT 2C receptor	B0VD6K	8-[4-(4-Fluorophenyl)piperazin-1-yl]-3-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene	Investigative	10689339	C19H17FN4S	352.4	C1CN(CCN1C2=CC=C(C=C2)F)C3=NC4=C(N5C3=CC=C5)SC=C4	IC50 = 72443.6 nM	Poor binder
T83813	5-HT 2C receptor	B0YGU1	N-Methyl-4-oxo-N-phenyl-5-(4-(piperidin-1-ylmethyl)phenethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamide	Investigative	44417896	C28H33N5O2	471.6	CN(C1=CC=CC=C1)C(=O)C2=NN3CCN(C(=O)C3=C2)CCC4=CC=C(C=C4)CN5CCCCC5	Ki ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B10YOM	5-(4-((Diethylamino)methyl)phenethyl)-N-(4-fluorophenyl)-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamide	Investigative	16659061	C26H30FN5O2	463.5	CCN(CC)CC1=CC=C(C=C1)CCN2CCN3C(=CC(=N3)C(=O)NC4=CC=C(C=C4)F)C2=O	Ki ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B18HYR	Pindolol	Investigative	4828	C14H20N2O2	248.32	CC(C)NCC(COC1=CC=CC2=C1C=CN2)O	Ki = 54000 nM	Poor binder
T83813	5-HT 2C receptor	B18QKG	2-(((8-((6-(4-Chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3(4H)-yl)methyl)quinolin-3-yl)methyl)(methyl)amino)-N,N-dimethylacetamide	Investigative	44416839	C28H26ClN5O2S	532.1	CN(C)C(=O)CN(C)CC1=CN=C2C(=C1)C=CC=C2CN3C=NC4=C(C3=O)SC(=C4)C5=CC=C(C=C5)Cl	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B1S6ZJ	6-(4-Chlorophenyl)-3-((3-((4-(methylsulfonyl)piperazin-1-yl)methyl)quinolin-8-yl)methyl)thieno[3,2-d]pyrimidin-4(3H)-one	Investigative	44416966	C28H26ClN5O3S2	580.1	CS(=O)(=O)N1CCN(CC1)CC2=CN=C3C(=C2)C=CC=C3CN4C=NC5=C(C4=O)SC(=C5)C6=CC=C(C=C6)Cl	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B20VBS	N-[(2S)-6-[[[2-(Dimethylamino)-2-oxoethyl]-methylamino]methyl]-1,2,3,4-tetrahydronaphthalen-2-yl]-4-(4-fluorophenyl)-N-methylbenzamide	Investigative	44417904	C30H34FN3O2	487.6	CN(C)C(=O)CN(C)CC1=CC2=C(C[C@H](CC2)N(C)C(=O)C3=CC=C(C=C3)C4=CC=C(C=C4)F)C=C1	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B25ZNE	5-[4-(4-Fluorobenzyl)-1-piperazinyl]pyrrolo[1,2-a]thieno[2,3-e]pyrazine	Investigative	10808909	C20H19FN4S	366.5	C1CN(CCN1CC2=CC=C(C=C2)F)C3=NC4=C(C=CS4)N5C3=CC=C5	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B2BFC1	4-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-7-chloropyrrolo[1,2-a]quinoxaline	Investigative	19978059	C23H21ClN4O2	420.9	C1CN(CCN1CC2=CC3=C(C=C2)OCO3)C4=NC5=C(C=CC(=C5)Cl)N6C4=CC=C6	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B35AWE	7-(4-Phenylpiperazin-1-yl)-2,8,13-triazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7,10,12-hexaene	Investigative	10853821	C20H19N5	329.4	C1CN(CCN1C2=CC=CC=C2)C3=NC4=C(N=CC=C4)N5C3=CC=C5	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B35XGW	N-[(2S)-6-[(Dimethylamino)methyl]-1,2,3,4-tetrahydronaphthalen-2-yl]-4-(4-fluorophenyl)-N-methylbenzamide	Investigative	11270012	C27H29FN2O	416.5	CN(C)CC1=CC2=C(C[C@H](CC2)N(C)C(=O)C3=CC=C(C=C3)C4=CC=C(C=C4)F)C=C1	IC50 = 55000 nM	Poor binder
T83813	5-HT 2C receptor	B3J0XM	6-(4-Fluoro-phenyl)-N-(3-morpholin-4-ylmethyl-quinolin-8-ylmethyl)-nicotinamide	Investigative	44416650	C27H25FN4O2	456.5	C1COCCN1CC2=CN=C3C(=C2)C=CC=C3CNC(=O)C4=CN=C(C=C4)C5=CC=C(C=C5)F	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B3UF9I	7-[4-[(2,4-Dichlorophenyl)methyl]piperazin-1-yl]-2,8,13-triazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7,10,12-hexaene	Investigative	10645335	C21H19Cl2N5	412.3	C1CN(CCN1CC2=C(C=C(C=C2)Cl)Cl)C3=NC4=C(N=CC=C4)N5C3=CC=C5	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B4YIP7	(S)-N-(6-((4-Acetylpiperazin-1-yl)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-5-(4-fluorophenyl)-N-methylpicolinamide	Investigative	44417892	C30H33FN4O2	500.6	CC(=O)N1CCN(CC1)CC2=CC3=C(C[C@H](CC3)N(C)C(=O)C4=NC=C(C=C4)C5=CC=C(C=C5)F)C=C2	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B53NFY	4-[[(6S)-6-[[4-(4-Fluorophenyl)benzoyl]-methylamino]-5,6,7,8-tetrahydronaphthalen-2-yl]methyl]piperazine-1-carboxamide	Investigative	44418004	C30H33FN4O2	500.6	CN([C@H]1CCC2=C(C1)C=CC(=C2)CN3CCN(CC3)C(=O)N)C(=O)C4=CC=C(C=C4)C5=CC=C(C=C5)F	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B56UVM	2-Propyl-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepin-3-one	Investigative	14515724	C10H16N2O2	196.25	CCCN1C(=O)C2=C(O1)CCNCC2	Ki = 100000 nM	Poor binder
T83813	5-HT 2C receptor	B5CAY3	4-(4-Fluorophenyl)-N-methyl-N-[(2S)-6-[(3-oxopiperazin-1-yl)methyl]-1,2,3,4-tetrahydronaphthalen-2-yl]benzamide	Investigative	44417901	C29H30FN3O2	471.6	CN([C@H]1CCC2=C(C1)C=CC(=C2)CN3CCNC(=O)C3)C(=O)C4=CC=C(C=C4)C5=CC=C(C=C5)F	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B5L4SY	7-(4-Benzylpiperazin-1-yl)-12-methoxy-2,8,13-triazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7,10,12-hexaene	Investigative	10667071	C22H23N5O	373.5	COC1=NC2=C(C=C1)N=C(C3=CC=CN32)N4CCN(CC4)CC5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B5LNU1	6-(4-Chlorophenyl)-3-((3-((4-hydroxypiperidin-1-yl)methyl)quinolin-8-yl)methyl)thieno[3,2-d]pyrimidin-4(3H)-one	Investigative	16046157	C28H25ClN4O2S	517	C1CN(CCC1O)CC2=CN=C3C(=C2)C=CC=C3CN4C=NC5=C(C4=O)SC(=C5)C6=CC=C(C=C6)Cl	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B5LT6J	6-(4-Chlorophenyl)-3-((3-(pyrrolidin-1-ylmethyl)quinolin-8-yl)methyl)thieno[3,2-d]pyrimidin-4(3H)-one	Investigative	44416929	C27H23ClN4OS	487	C1CCN(C1)CC2=CN=C3C(=C2)C=CC=C3CN4C=NC5=C(C4=O)SC(=C5)C6=CC=C(C=C6)Cl	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B62XWU	Ethyl 2-[4-(3-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaen-8-yl)piperazin-1-yl]acetate	Investigative	10569470	C17H20N4O2S	344.4	CCOC(=O)CN1CCN(CC1)C2=NC3=C(N4C2=CC=C4)SC=C3	IC50 = 61659.5 nM	Poor binder
T83813	5-HT 2C receptor	B6GSB4	8-(3,6-Dihydro-2H-pyridin-1-yl)-3-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene	Investigative	44306007	C14H13N3S	255.34	C1CN(CC=C1)C2=NC3=C(N4C2=CC=C4)SC=C3	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B6RWT0	(S)-6-(4-Fluorophenyl)-N-methyl-N-(6-((3-oxopiperazin-1-yl)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)nicotinamide	Investigative	44417960	C28H29FN4O2	472.6	CN([C@H]1CCC2=C(C1)C=CC(=C2)CN3CCNC(=O)C3)C(=O)C4=CN=C(C=C4)C5=CC=C(C=C5)F	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B6SQI9	1-Benzo[1,3]dioxol-5-yl-4-[4-(3-methoxy-benzyl)-piperazin-1-yl]-cyclohexanol	Investigative	9845261	C25H32N2O4	424.5	COC1=CC=CC(=C1)CN2CCN(CC2)C3CCC(CC3)(C4=CC5=C(C=C4)OCO5)O	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B7JUN4	8-(4-Benzylpiperazin-1-yl)-4,5-dimethyl-3-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene	Investigative	10809561	C22H24N4S	376.5	CC1=C(SC2=C1N=C(C3=CC=CN32)N4CCN(CC4)CC5=CC=CC=C5)C	IC50 = 154881.66 nM	Poor binder
T83813	5-HT 2C receptor	B80UPR	7-(4-Benzylpiperazin-1-yl)-10-methyl-2,8,13-triazatricyclo[7.4.0.02,6]trideca-1(13),3,5,7,9,11-hexaene	Investigative	10498554	C22H23N5	357.5	CC1=C2C(=NC=C1)N3C=CC=C3C(=N2)N4CCN(CC4)CC5=CC=CC=C5	IC50 = 57543.99 nM	Poor binder
T83813	5-HT 2C receptor	B8M0LK	CID 20026449	Investigative	20026449	C9H14N2O2	182.22	CCOC1=NOC2=C1CCNCC2	Ki = 100000 nM	Poor binder
T83813	5-HT 2C receptor	B8Z3DQ	(S)-N-(6-((Dimethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-N-methyl-4-(pyridin-2-yl)benzamide	Investigative	16659197	C26H29N3O	399.5	CN(C)CC1=CC2=C(C[C@H](CC2)N(C)C(=O)C3=CC=C(C=C3)C4=CC=CC=N4)C=C1	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B9E7XN	6-(4-Chlorophenyl)-3-((3-((4-methylpiperazin-1-yl)methyl)quinolin-8-yl)methyl)thieno[3,2-d]pyrimidin-4(3H)-one	Investigative	44416840	C28H26ClN5OS	516.1	CN1CCN(CC1)CC2=CN=C3C(=C2)C=CC=C3CN4C=NC5=C(C4=O)SC(=C5)C6=CC=C(C=C6)Cl	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B9I1VO	7-(4-Benzylpiperazin-1-yl)-12-phenylmethoxy-2,8,13-triazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7,10,12-hexaene	Investigative	11797762	C28H27N5O	449.5	C1CN(CCN1CC2=CC=CC=C2)C3=NC4=C(N=C(C=C4)OCC5=CC=CC=C5)N6C3=CC=C6	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	B9T5DL	12-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-6,11,17-triazatetracyclo[8.7.0.02,7.013,17]heptadeca-1(10),2(7),3,5,8,11,13,15-octaene	Investigative	11797241	C26H23N5O2	437.5	C1CN(CCN1CC2=CC3=C(C=C2)OCO3)C4=NC5=C(C6=C(C=C5)N=CC=C6)N7C4=CC=C7	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BA93IU	Ethyl 4-(3-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaen-8-yl)piperazine-1-carboxylate	Investigative	10687868	C16H18N4O2S	330.4	CCOC(=O)N1CCN(CC1)C2=NC3=C(N4C2=CC=C4)SC=C3	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BBO96J	4-[4-[(4-Fluorophenyl)methyl]piperazin-1-yl]-7-methylpyrrolo[1,2-a]quinoxaline	Investigative	10571450	C23H23FN4	374.5	CC1=CC2=C(C=C1)N3C=CC=C3C(=N2)N4CCN(CC4)CC5=CC=C(C=C5)F	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BFX03Y	N-[(2S)-6-[(4-Acetylpiperazin-1-yl)methyl]-1,2,3,4-tetrahydronaphthalen-2-yl]-4-(4-fluorophenyl)-N-methylbenzamide	Investigative	44417928	C31H34FN3O2	499.6	CC(=O)N1CCN(CC1)CC2=CC3=C(C[C@H](CC3)N(C)C(=O)C4=CC=C(C=C4)C5=CC=C(C=C5)F)C=C2	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BI2EY5	8-Piperidin-1-yl-3-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene	Investigative	10539093	C14H15N3S	257.36	C1CCN(CC1)C2=NC3=C(N4C2=CC=C4)SC=C3	IC50 = 57543.99 nM	Poor binder
T83813	5-HT 2C receptor	BI6V1L	Schembl21373237	Investigative	122195446	C24H27N3O4	421.5	CN(CC(=O)C1=C(NC2=CC=CC=C21)C3=CC=C(C=C3)OC)CC(=O)N4CCOCC4	IC50 = 51286.14 nM	Poor binder
T83813	5-HT 2C receptor	BIW6P5	7,12-Bis(4-benzylpiperazin-1-yl)-2,8,13-triazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7,10,12-hexaene	Investigative	10553922	C32H35N7	517.7	C1CN(CCN1CC2=CC=CC=C2)C3=NC4=C(C=C3)N=C(C5=CC=CN54)N6CCN(CC6)CC7=CC=CC=C7	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BJ2P7U	Ethyl 4-(2,8,13-triazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7,10,12-hexaen-7-yl)piperazine-1-carboxylate	Investigative	10663820	C17H19N5O2	325.4	CCOC(=O)N1CCN(CC1)C2=NC3=C(N=CC=C3)N4C2=CC=C4	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BJ6W9A	8-(4-Phenylpiperidin-1-yl)-3-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene	Investigative	10568666	C20H19N3S	333.5	C1CN(CCC1C2=CC=CC=C2)C3=NC4=C(N5C3=CC=C5)SC=C4	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BJ7EG3	N-(4-Fluorophenyl)-N-methyl-4-oxo-5-(4-(piperidin-1-ylmethyl)phenethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamide	Investigative	44417912	C28H32FN5O2	489.6	CN(C1=CC=C(C=C1)F)C(=O)C2=NN3CCN(C(=O)C3=C2)CCC4=CC=C(C=C4)CN5CCCCC5	Ki ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BL2P7B	(2S)-1-[[(6S)-6-[[4-(4-Fluorophenyl)benzoyl]-methylamino]-5,6,7,8-tetrahydronaphthalen-2-yl]methyl]-N,N-dimethylpyrrolidine-2-carboxamide	Investigative	44417895	C32H36FN3O2	513.6	CN(C)C(=O)[C@@H]1CCCN1CC2=CC3=C(C[C@H](CC3)N(C)C(=O)C4=CC=C(C=C4)C5=CC=C(C=C5)F)C=C2	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BL4N2M	N-(4-Fluorophenyl)-1-oxo-2-(4-(piperidin-1-ylmethyl)phenethyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-7-carboxamide	Investigative	44417987	C28H31FN4O2	474.6	C1CCN(CC1)CC2=CC=C(C=C2)CCN3CCN4C=C(C=C4C3=O)C(=O)NC5=CC=C(C=C5)F	Ki ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BLPU59	(S)-N-(6-((Dimethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-N-methyl-4-(pyridin-3-yl)benzamide	Investigative	44417985	C26H29N3O	399.5	CN(C)CC1=CC2=C(C[C@H](CC2)N(C)C(=O)C3=CC=C(C=C3)C4=CN=CC=C4)C=C1	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BLZ87E	N-[(2S)-6-[(1,1-Dioxo-1,4-thiazinan-4-yl)methyl]-1,2,3,4-tetrahydronaphthalen-2-yl]-4-(4-fluorophenyl)-N-methylbenzamide	Investigative	44417898	C29H31FN2O3S	506.6	CN([C@H]1CCC2=C(C1)C=CC(=C2)CN3CCS(=O)(=O)CC3)C(=O)C4=CC=C(C=C4)C5=CC=C(C=C5)F	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BN5PZ9	N-(3-Fluorophenyl)-4-oxo-5-(4-(piperidin-1-ylmethyl)phenethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamide	Investigative	44417909	C27H30FN5O2	475.6	C1CCN(CC1)CC2=CC=C(C=C2)CCN3CCN4C(=CC(=N4)C(=O)NC5=CC(=CC=C5)F)C3=O	Ki ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BO3H2X	8-(4-Phenylpiperazin-1-yl)-3-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene	Investigative	10496957	C19H18N4S	334.4	C1CN(CCN1C2=CC=CC=C2)C3=NC4=C(N5C3=CC=C5)SC=C4	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BP5KM8	(S)-N-(6-((Dimethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-N-methyl-4-(pyridin-4-yl)benzamide	Investigative	44417900	C26H29N3O	399.5	CN(C)CC1=CC2=C(C[C@H](CC2)N(C)C(=O)C3=CC=C(C=C3)C4=CC=NC=C4)C=C1	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BQHF10	7-[4-[(4-Fluorophenyl)methyl]piperazin-1-yl]-12-methoxy-2,8,13-triazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7,10,12-hexaene	Investigative	10715484	C22H22FN5O	391.4	COC1=NC2=C(C=C1)N=C(C3=CC=CN32)N4CCN(CC4)CC5=CC=C(C=C5)F	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BQX16O	7-Chloro-4-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]pyrrolo[1,2-a]quinoxaline	Investigative	10620679	C22H20ClFN4	394.9	C1CN(CCN1CC2=CC=C(C=C2)F)C3=NC4=C(C=CC(=C4)Cl)N5C3=CC=C5	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BSM3N9	7-[4-[(4-Fluorophenyl)methyl]piperazin-1-yl]-10-methyl-2,8,13-triazatricyclo[7.4.0.02,6]trideca-1(13),3,5,7,9,11-hexaene	Investigative	10714509	C22H22FN5	375.4	CC1=C2C(=NC=C1)N3C=CC=C3C(=N2)N4CCN(CC4)CC5=CC=C(C=C5)F	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BU3K2W	(4-Fluorophenyl)-[4-(3-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaen-8-yl)piperazin-1-yl]methanone	Investigative	10547809	C20H17FN4OS	380.4	C1CN(CCN1C2=NC3=C(N4C2=CC=C4)SC=C3)C(=O)C5=CC=C(C=C5)F	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BU8DL1	4-(4-Fluorophenyl)-N-[[3-[(4-methylsulfonylpiperidin-1-yl)methyl]quinolin-8-yl]methyl]benzamide	Investigative	44416738	C30H30FN3O3S	531.6	CS(=O)(=O)C1CCN(CC1)CC2=CN=C3C(=C2)C=CC=C3CNC(=O)C4=CC=C(C=C4)C5=CC=C(C=C5)F	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BVI90L	8-[4-(4-Chlorophenyl)piperazin-1-yl]-3-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene	Investigative	10523090	C19H17ClN4S	368.9	C1CN(CCN1C2=CC=C(C=C2)Cl)C3=NC4=C(N5C3=CC=C5)SC=C4	IC50 = 102329.3 nM	Poor binder
T83813	5-HT 2C receptor	BW07ZT	N-[(2S)-6-[(1,1-Dioxo-1,4-thiazinan-4-yl)methyl]-1,2,3,4-tetrahydronaphthalen-2-yl]-N-methyl-4-pyridin-2-ylbenzamide	Investigative	44417958	C28H31N3O3S	489.6	CN([C@H]1CCC2=C(C1)C=CC(=C2)CN3CCS(=O)(=O)CC3)C(=O)C4=CC=C(C=C4)C5=CC=CC=N5	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BWN5A6	(S)-N-(6-((4-Acetylpiperazin-1-yl)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-N-methyl-4-(pyridin-2-yl)benzamide	Investigative	44417954	C30H34N4O2	482.6	CC(=O)N1CCN(CC1)CC2=CC3=C(C[C@H](CC3)N(C)C(=O)C4=CC=C(C=C4)C5=CC=CC=N5)C=C2	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BWP20G	N-(2,6-Dimethoxybenzyl)-4-bromo-2,5-dimethoxybenzeneethanamine	Investigative	122180973	C19H24BrNO4	410.3	COC1=C(C(=CC=C1)OC)CNCCC2=CC(=C(C=C2OC)Br)OC	EC50 = 87096.36 nM	Poor binder
T83813	5-HT 2C receptor	BYRB51	8-(4-Benzylpiperazino)pyrido[2,3-h]pyrrolo[1,2-a]quinoxaline	Investigative	10834414	C25H23N5	393.5	C1CN(CCN1CC2=CC=CC=C2)C3=NC4=C(C5=C(C=C4)N=CC=C5)N6C3=CC=C6	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BYX93L	4-[4-[(4-Fluorophenyl)methyl]piperazin-1-yl]-7-methoxypyrrolo[1,2-a]quinoxaline	Investigative	10452995	C23H23FN4O	390.5	COC1=CC2=C(C=C1)N3C=CC=C3C(=N2)N4CCN(CC4)CC5=CC=C(C=C5)F	IC50 ~ 100000 nM	Poor binder
T83813	5-HT 2C receptor	BZ0GL4	(S)-5-(4-Chlorophenyl)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-N-methylpicolinamide	Investigative	44417919	C26H28ClN3O	434	CN(C)CC1=CC2=C(C[C@H](CC2)N(C)C(=O)C3=NC=C(C=C3)C4=CC=C(C=C4)Cl)C=C1	IC50 = 56000 nM	Poor binder