TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T86462	Transthyretin	D00CSQ	Triclosan	Approved	5564	C12H7Cl3O2	289.5	C1=CC(=C(C=C1Cl)O)OC2=C(C=C(C=C2)Cl)Cl	IC50 = 53500 nM	Poor binder
T86462	Transthyretin	D00HGB	Niflumic Acid	Approved	4488	C13H9F3N2O2	282.22	C1=CC(=CC(=C1)NC2=C(C=CC=N2)C(=O)O)C(F)(F)F	IC50 = 130000 nM	Poor binder
T86462	Transthyretin	D05VIX	Gemfibrozil	Approved	3463	C15H22O3	250.33	CC1=CC(=C(C=C1)C)OCCCC(C)(C)C(=O)O	IC50 = 180000 nM	Poor binder
T86462	Transthyretin	D08IFL	Meclofenamic acid	Approved	4037	C14H11Cl2NO2	296.1	CC1=C(C(=C(C=C1)Cl)NC2=CC=CC=C2C(=O)O)Cl	IC50 = 50000 nM	Poor binder
T86462	Transthyretin	D0T8VY	Aceclofenac	Approved	71771	C16H13Cl2NO4	354.2	C1=CC=C(C(=C1)CC(=O)OCC(=O)O)NC2=C(C=CC=C2Cl)Cl	IC50 = 170000 nM	Poor binder
T86462	Transthyretin	D0TG1H	Diclofenac	Approved	3033	C14H11Cl2NO2	296.1	C1=CC=C(C(=C1)CC(=O)O)NC2=C(C=CC=C2Cl)Cl	IC50 = 140000 nM	Poor binder
T86462	Transthyretin	B1V8PB	4-(2,4-Dinitrophenoxy)-3-hydroxybenzaldehyde	Investigative	44436913	C13H8N2O7	304.21	C1=CC(=C(C=C1C=O)O)OC2=C(C=C(C=C2)[N+](=O)[O-])[N+](=O)[O-]	IC50 = 55000 nM	Poor binder
T86462	Transthyretin	B37CBT	(E/Z)-5-Iodo-3-(4-iodophenylimino)indolin-2-one	Investigative	136180743	C14H8I2N2O	474.03	C1=CC(=CC=C1N=C2C3=C(C=CC(=C3)I)NC2=O)I	IC50 ~ 50000 nM	Poor binder
T86462	Transthyretin	B3FDW2	3-(4-Iodo-phenylimino)-5-methyl-1,3-dihydro-indol-2-one	Investigative	135492657	C15H11IN2O	362.16	CC1=CC2=C(C=C1)NC(=O)C2=NC3=CC=C(C=C3)I	IC50 ~ 50000 nM	Poor binder
T86462	Transthyretin	B4AUX3	(E/Z)-5-Bromo-3-(4-iodophenylimino)indolin-2-one	Investigative	135559314	C14H8BrIN2O	427.03	C1=CC(=CC=C1N=C2C3=C(C=CC(=C3)Br)NC2=O)I	IC50 ~ 50000 nM	Poor binder
T86462	Transthyretin	B4K3BG	5-Bromo-3-(4-methoxy-phenylimino)-1,3-dihydro-indol-2-one	Investigative	135400370	C15H11BrN2O2	331.16	COC1=CC=C(C=C1)N=C2C3=C(C=CC(=C3)Br)NC2=O	IC50 ~ 50000 nM	Poor binder
T86462	Transthyretin	B9ZS6V	(E/Z)-5-Iodo-3-(phenylimino)indolin-2-one	Investigative	135985428	C14H9IN2O	348.14	C1=CC=C(C=C1)N=C2C3=C(C=CC(=C3)I)NC2=O	IC50 ~ 50000 nM	Poor binder
T86462	Transthyretin	BE29QG	3-(Phenylimino)oxindole	Investigative	135442567	C14H10N2O	222.24	C1=CC=C(C=C1)N=C2C3=CC=CC=C3NC2=O	IC50 ~ 50000 nM	Poor binder
T86462	Transthyretin	BJ8OD4	(E/Z)-3-(4-Iodophenylimino)-1-methylindolin-2-one	Investigative	23912193	C15H11IN2O	362.16	CN1C2=CC=CC=C2C(=NC3=CC=C(C=C3)I)C1=O	IC50 ~ 50000 nM	Poor binder
T86462	Transthyretin	BKZ14S	(E/Z)-5-Iodo-3-(4-methoxyphenylimino)indolin-2-one	Investigative	136180742	C15H11IN2O2	378.16	COC1=CC=C(C=C1)N=C2C3=C(C=CC(=C3)I)NC2=O	IC50 ~ 50000 nM	Poor binder
T86462	Transthyretin	BL6D1U	Phenethyl Dimethyl Caffeate	Investigative	5353592	C19H20O4	312.4	COC1=C(C=C(C=C1)/C=C/C(=O)OCCC2=CC=CC=C2)OC	EC50 = 58000 nM	Poor binder
T86462	Transthyretin	BN2TL3	(3Z)-3-[(4-Iodophenyl)imino]-1,3-dihydro-2H-indol-2-one	Investigative	135411934	C14H9IN2O	348.14	C1=CC=C2C(=C1)C(=NC3=CC=C(C=C3)I)C(=O)N2	IC50 ~ 50000 nM	Poor binder
T86462	Transthyretin	BNG0B6	(3Z)-3-[(4-Methoxyphenyl)imino]-5-methyl-1,3-dihydro-2H-indol-2-one	Investigative	135432194	C16H14N2O2	266.29	CC1=CC2=C(C=C1)NC(=O)C2=NC3=CC=C(C=C3)OC	IC50 ~ 50000 nM	Poor binder
T86462	Transthyretin	BP06XR	(E/Z)-3-(4-Iodophenylimino)-5-nitroindolin-2-one	Investigative	135755896	C14H8IN3O3	393.14	C1=CC(=CC=C1N=C2C3=C(C=CC(=C3)[N+](=O)[O-])NC2=O)I	IC50 ~ 50000 nM	Poor binder
T86462	Transthyretin	BPHC46	2H-Indol-2-one, 1,3-dihydro-3-[(4-methoxyphenyl)imino]-5-nitro-	Investigative	135406035	C15H11N3O4	297.26	COC1=CC=C(C=C1)N=C2C3=C(C=CC(=C3)[N+](=O)[O-])NC2=O	IC50 ~ 50000 nM	Poor binder
T86462	Transthyretin	BUJ4D9	Methyl caffeate	Investigative	689075	C10H10O4	194.18	COC(=O)/C=C/C1=CC(=C(C=C1)O)O	EC50 = 67000 nM	Poor binder
T86462	Transthyretin	BZ56QC	3-(4-Methylanilino)indol-2-one	Investigative	135412515	C15H12N2O	236.27	CC1=CC=C(C=C1)N=C2C3=CC=CC=C3NC2=O	IC50 ~ 50000 nM	Poor binder
T86462	Transthyretin	D0SP2O	1H-Indole-2,3-dione	Investigative	7054	C8H5NO2	147.13	C1=CC=C2C(=C1)C(=O)C(=O)N2	IC50 ~ 50000 nM	Poor binder
T86462	Transthyretin	D0V9EN	3,4-Dihydroxycinnamic Acid	Investigative	689043	C9H8O4	180.16	C1=CC(=C(C=C1/C=C/C(=O)O)O)O	EC50 = 97000 nM	Poor binder