TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T87109	Casein kinase I delta	B0KW1R	N-[3-[4-[[Amino-[4-chloro-3-(trifluoromethyl)anilino]methylidene]amino]anilino]phenyl]acetamide;hydrochloride	Investigative	90644407	C22H20Cl2F3N5O	498.3	CC(=O)NC1=CC=CC(=C1)NC2=CC=C(C=C2)N=C(N)NC3=CC(=C(C=C3)Cl)C(F)(F)F.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	B24FDH	Sodium;2-[4-[2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyrimidin-7-yl]triazol-1-yl]acetate	Investigative	118707523	C21H14FN8NaO2S	484.4	CSC1=NC=CC(=N1)C2=C(N=C3N2C=CC(=N3)C4=CN(N=N4)CC(=O)[O-])C5=CC=C(C=C5)F.[Na+]	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	B3H7WV	2-(4-Fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyrimidin-7-amine	Investigative	9798589	C17H13FN6S	352.4	CSC1=NC=CC(=N1)C2=C(N=C3N2C=CC(=N3)N)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	B3PAC6	1-[3-[[4-(Diaminomethylideneamino)phenyl]methyl]phenyl]-2-phenylguanidine;hydrochloride	Investigative	90644434	C21H23ClN6	394.9	C1=CC=C(C=C1)N=C(N)NC2=CC=CC(=C2)CC3=CC=C(C=C3)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	B3QRP5	1-[3-[4-(Diaminomethylideneamino)phenoxy]phenyl]-2-phenylguanidine;hydrochloride	Investigative	90644432	C20H21ClN6O	396.9	C1=CC=C(C=C1)N=C(N)NC2=CC(=CC=C2)OC3=CC=C(C=C3)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	B46CZS	2-[3-[4-(Diaminomethylideneamino)benzoyl]phenyl]guanidine;hydrochloride	Investigative	90644412	C15H17ClN6O	332.79	C1=CC(=CC(=C1)N=C(N)N)C(=O)C2=CC=C(C=C2)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	B54YHZ	N-[3-[4-[[Amino-[4-chloro-3-(trifluoromethyl)anilino]methylidene]amino]phenoxy]phenyl]acetamide;hydrochloride	Investigative	90644405	C22H19Cl2F3N4O2	499.3	CC(=O)NC1=CC(=CC=C1)OC2=CC=C(C=C2)N=C(N)NC3=CC(=C(C=C3)Cl)C(F)(F)F.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	B81JYI	Disodium;2-[4-[2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyrimidin-7-yl]triazol-1-yl]ethyl-dioxido-oxo-lambda5-phosphane	Investigative	118707526	C21H16FN8Na2O3PS	556.4	CSC1=NC=CC(=N1)C2=C(N=C3N2C=CC(=N3)C4=CN(N=N4)CCP(=O)([O-])[O-])C5=CC=C(C=C5)F.[Na+].[Na+]	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	B84EBL	N-[4-[3-(4,5-Dihydro-1H-imidazol-2-ylamino)phenoxy]phenyl]-4,5-dihydro-1H-imidazol-2-amine;hydrochloride	Investigative	90644418	C18H21ClN6O	372.9	C1CN=C(N1)NC2=CC=C(C=C2)OC3=CC=CC(=C3)NC4=NCCN4.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	B97OTQ	7-Ethynyl-2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyrimidine	Investigative	118707522	C19H12FN5S	361.4	CSC1=NC=CC(=N1)C2=C(N=C3N2C=CC(=N3)C#C)C4=CC=C(C=C4)F	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	BB7T4M	4-[2-(4-Ethynylphenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-methylsulfanylpyrimidine	Investigative	118707543	C22H15FN4S	386.4	CSC1=NC=CC(=N1)C2=C(N=C(N2)C3=CC=C(C=C3)C#C)C4=CC=C(C=C4)F	IC50 = 66300 nM	Poor binder
T87109	Casein kinase I delta	BBG6Q5	2-[4-[3-(Diaminomethylideneamino)anilino]phenyl]-1-phenylguanidine;hydrochloride	Investigative	90644430	C20H22ClN7	395.9	C1=CC=C(C=C1)NC(=NC2=CC=C(C=C2)NC3=CC(=CC=C3)N=C(N)N)N.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	BD5O9Y	2-(4-Fluorophenyl)-3-[2-[[(1S)-1-phenylethyl]amino]pyrimidin-4-yl]imidazo[1,2-a]pyrimidin-7-amine	Investigative	44124695	C24H20FN7	425.5	C[C@@H](C1=CC=CC=C1)NC2=NC=CC(=N2)C3=C(N=C4N3C=CC(=N4)N)C5=CC=C(C=C5)F	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	BGM0A4	1-[4-Chloro-3-(trifluoromethyl)phenyl]-2-[4-[3-(diaminomethylideneamino)phenoxy]phenyl]guanidine;hydrochloride	Investigative	90644436	C21H19Cl2F3N6O	499.3	C1=CC(=CC(=C1)OC2=CC=C(C=C2)N=C(N)NC3=CC(=C(C=C3)Cl)C(F)(F)F)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	BHB48N	2-[4-[3-(Diaminomethylideneamino)benzoyl]phenyl]-1-phenylguanidine;hydrochloride	Investigative	90644426	C21H21ClN6O	408.9	C1=CC=C(C=C1)NC(=NC2=CC=C(C=C2)C(=O)C3=CC(=CC=C3)N=C(N)N)N.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	BIF2G7	2-[3-[[4-(Diaminomethylideneamino)phenyl]methyl]phenyl]guanidine;hydrochloride	Investigative	90644414	C15H19ClN6	318.8	C1=CC(=CC(=C1)N=C(N)N)CC2=CC=C(C=C2)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	BO31FR	1-[4-Chloro-3-(trifluoromethyl)phenyl]-2-[4-[3-(diaminomethylideneamino)benzoyl]phenyl]guanidine;hydrochloride	Investigative	90644438	C22H19Cl2F3N6O	511.3	C1=CC(=CC(=C1)N=C(N)N)C(=O)C2=CC=C(C=C2)N=C(N)NC3=CC(=C(C=C3)Cl)C(F)(F)F.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	BOGE79	[3-(4,5-Dihydro-1H-imidazol-2-ylamino)phenyl]-[4-(4,5-dihydro-1H-imidazol-2-ylamino)phenyl]methanone;hydrochloride	Investigative	90644420	C19H21ClN6O	384.9	C1CN=C(N1)NC2=CC=C(C=C2)C(=O)C3=CC(=CC=C3)NC4=NCCN4.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	BRVO09	2-[4-Chloro-3-(trifluoromethyl)phenyl]-1-[3-[4-(diaminomethylideneamino)phenoxy]phenyl]guanidine;hydrochloride	Investigative	90644401	C21H19Cl2F3N6O	499.3	C1=CC(=CC(=C1)OC2=CC=C(C=C2)N=C(N)N)NC(=NC3=CC(=C(C=C3)Cl)C(F)(F)F)N.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	BSZK98	2-[3-[4-(Diaminomethylideneamino)phenoxy]phenyl]guanidine;hydrochloride	Investigative	90644410	C14H17ClN6O	320.78	C1=CC(=CC(=C1)OC2=CC=C(C=C2)N=C(N)N)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	BT9VH6	6-(2,9-Diazaspiro[5.5]undecan-9-Yl)-9h-Purine	Investigative	70789255	C14H20N6	272.35	C1CC2(CCN(CC2)C3=NC=NC4=C3NC=N4)CNC1	IC50 = 97000 nM	Poor binder
T87109	Casein kinase I delta	BUOE04	N-[4-[[3-(4,5-Dihydro-1H-imidazol-2-ylamino)phenyl]methyl]phenyl]-4,5-dihydro-1H-imidazol-2-amine;hydrochloride	Investigative	90644422	C19H23ClN6	370.9	C1CN=C(N1)NC2=CC=C(C=C2)CC3=CC(=CC=C3)NC4=NCCN4.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	BV2UG1	2-[3-[4-(Diaminomethylideneamino)anilino]phenyl]guanidine;hydrochloride	Investigative	90644416	C14H18ClN7	319.79	C1=CC(=CC(=C1)N=C(N)N)NC2=CC=C(C=C2)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	BW02UO	2-[4-[4-(Diaminomethylideneamino)phenoxy]phenyl]guanidine;hydrochloride	Investigative	90644409	C14H17ClN6O	320.78	C1=CC(=CC=C1N=C(N)N)OC2=CC=C(C=C2)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	BXK94F	2-[4-Chloro-3-(trifluoromethyl)phenyl]-1-[3-[[4-(diaminomethylideneamino)phenyl]methyl]phenyl]guanidine;hydrochloride	Investigative	90644403	C22H21Cl2F3N6	497.3	C1=CC(=CC(=C1)NC(=NC2=CC(=C(C=C2)Cl)C(F)(F)F)N)CC3=CC=C(C=C3)N=C(N)N.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	BXPD02	1-[4-Chloro-3-(trifluoromethyl)phenyl]-2-[4-[3-(diaminomethylideneamino)anilino]phenyl]guanidine;hydrochloride	Investigative	90644442	C21H20Cl2F3N7	498.3	C1=CC(=CC(=C1)N=C(N)N)NC2=CC=C(C=C2)N=C(N)NC3=CC(=C(C=C3)Cl)C(F)(F)F.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	BYQM45	2-[4-[[3-(Diaminomethylideneamino)phenyl]methyl]phenyl]-1-phenylguanidine;hydrochloride	Investigative	90644428	C21H23ClN6	394.9	C1=CC=C(C=C1)NC(=NC2=CC=C(C=C2)CC3=CC(=CC=C3)N=C(N)N)N.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	BZ8LJ2	2-[4-[3-(Diaminomethylideneamino)phenoxy]phenyl]-1-phenylguanidine;hydrochloride	Investigative	90644424	C20H21ClN6O	396.9	C1=CC=C(C=C1)NC(=NC2=CC=C(C=C2)OC3=CC=CC(=C3)N=C(N)N)N.Cl	IC50 ~ 100000 nM	Poor binder
T87109	Casein kinase I delta	BZE97Y	1-[4-Chloro-3-(trifluoromethyl)phenyl]-2-[4-[[3-(diaminomethylideneamino)phenyl]methyl]phenyl]guanidine;hydrochloride	Investigative	90644440	C22H21Cl2F3N6	497.3	C1=CC(=CC(=C1)N=C(N)N)CC2=CC=C(C=C2)N=C(N)NC3=CC(=C(C=C3)Cl)C(F)(F)F.Cl	IC50 ~ 100000 nM	Poor binder