TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T92458 Cytochrome P450 24 B0L2EK (E)-2-(Biphenyl-2-ylmethylene)-6-methoxy-3,4-dihydronaphthalen-1(2H)-one Investigative 52947291 C24H20O2 340.4 COC1=CC2=C(C=C1)C(=O)/C(=C/C3=CC=CC=C3C4=CC=CC=C4)/CC2 IC50 = 111100 nM Poor binder T92458 Cytochrome P450 24 B37DFS 2-(Biphenyl-2-ylmethyl)-6-methoxy-3,4-dihydronaphthalen-1(2H)-one Investigative 46945268 C24H22O2 342.4 COC1=CC2=C(C=C1)C(=O)C(CC2)CC3=CC=CC=C3C4=CC=CC=C4 IC50 = 127600 nM Poor binder T92458 Cytochrome P450 24 B5IFY0 4-Benzyl-N-(2-(1H-imidazol-1-yl)-2-phenylethyl)benzamide Investigative 49798930 C25H23N3O 381.5 C1=CC=C(C=C1)CC2=CC=C(C=C2)C(=O)NCC(C3=CC=CC=C3)N4C=CN=C4 IC50 = 72000 nM Poor binder T92458 Cytochrome P450 24 BB07FY 2-Bromo-Benzylidene Tetralone Investigative 11523005 C18H15BrO2 343.2 COC1=CC2=C(C=C1)C(=O)/C(=C/C3=CC=CC=C3Br)/CC2 IC50 = 122000 nM Poor binder