TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T92521	Cytochrome P450 1B1	D00ZFP	Estrone	Approved	5870	C18H22O2	270.4	C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CCC4=C3C=CC(=C4)O	IC50 ~ 50000 nM	Poor binder
T92521	Cytochrome P450 1B1	D08QMX	Estradiol	Approved	5757	C18H24O2	272.4	C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4)O	IC50 ~ 50000 nM	Poor binder
T92521	Cytochrome P450 1B1	D0U3EP	Resveratrol	Phase 3	445154	C14H12O3	228.24	C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O)O)O	IC50 = 55000 nM	Poor binder
T92521	Cytochrome P450 1B1	B0H5XT	2-[2-[2-[2-[2-(3-Fluorophenyl)-6,7,10-trimethoxy-4-oxobenzo[h]chromen-3-yl]oxyethoxy]ethoxy]ethoxy]ethyl 2-aminoacetate;hydrochloride	Investigative	118735543	C32H37ClFNO11	666.1	COC1=C2C(=CC3=C(C2=C(C=C1)OC)OC(=C(C3=O)OCCOCCOCCOCCOC(=O)CN)C4=CC(=CC=C4)F)OC.Cl	IC50 = 51200 nM	Poor binder
T92521	Cytochrome P450 1B1	B5UY1Q	2-[3,4-Bis(phenylmethoxy)phenyl]-6,7,10-trimethoxybenzo[h]chromen-4-one	Investigative	118735525	C36H30O7	574.6	COC1=C2C(=CC3=C(C2=C(C=C1)OC)OC(=CC3=O)C4=CC(=C(C=C4)OCC5=CC=CC=C5)OCC6=CC=CC=C6)OC	IC50 ~ 100000 nM	Poor binder
T92521	Cytochrome P450 1B1	BI8D0M	4-Aminobenzoic acid	Investigative	978	C7H7NO2	137.14	C1=CC(=CC=C1C(=O)O)N	IC50 ~ 120000 nM	Poor binder
T92521	Cytochrome P450 1B1	BIHK26	4-Methoxyestradiol	Investigative	68578	C19H26O3	302.4	C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4OC)O	Ki = 149000 nM	Poor binder
T92521	Cytochrome P450 1B1	BJ3IW6	4-[(e)-Phenyldiazenyl]morpholine	Investigative	282535	C10H13N3O	191.23	C1COCCN1N=NC2=CC=CC=C2	IC50 = 163000 nM	Poor binder
T92521	Cytochrome P450 1B1	D0I7GE	ALPHA-NAPHTHOFLAVONE	Investigative	11790	C19H12O2	272.3	C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C4=CC=CC=C4C=C3	IC50 ~ 50000 nM	Poor binder