TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T93515	P2Y purinoceptor 2	D0H2UB	Suramin	Phase 1	5361	C51H40N6O23S6	1297.3	CC1=C(C=C(C=C1)C(=O)NC2=C3C(=CC(=CC3=C(C=C2)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)NC(=O)C4=CC(=CC=C4)NC(=O)NC5=CC=CC(=C5)C(=O)NC6=C(C=CC(=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)C	IC50 = 50000 nM	Poor binder
T93515	P2Y purinoceptor 2	B0QIS4	((2R,3S,4R,5R)-3,4-Dihydroxy-5-(2-(methylamino)-4-oxopyrimidin-1(4H)-yl)tetrahydrofuran-2-yl)methyl dihydrogen phosphate	Investigative	52952496	C10H16N3O8P	337.22	CNC1=NC(=O)C=CN1[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T93515	P2Y purinoceptor 2	B2M1IU	1-(beta-D-Ribofuranosyl)-2-thio-uracil-5'-phosphate	Investigative	3081495	C9H13N2O8PS	340.25	C1=CN(C(=S)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T93515	P2Y purinoceptor 2	B2R5KC	5'-Uridylic acid, 3-(2-oxo-2-phenylethyl)-	Investigative	11993885	C17H19N2O10P	442.3	C1=CC=C(C=C1)C(=O)CN2C(=O)C=CN(C2=O)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T93515	P2Y purinoceptor 2	B2SEM0	6-Propyl-3-beta-D-ribofuranosyl(1H)pyrimidine-2,4-dione 5''-diphosphate	Investigative	11994013	C12H20N2O12P2	446.24	CCCC1=CC(=O)N(C(=O)N1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T93515	P2Y purinoceptor 2	B5LRM4	Diadenosine tetraphosphate	Investigative	21706	C20H28N10O19P4	836.4	C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)N	EC50 = 81000 nM	Poor binder
T93515	P2Y purinoceptor 2	B94SGX	CID 70692052	Investigative	70692052	C68H135BN14O18P4	1571.6	[B]P(=O)(OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=NC6=C(N=CN=C65)N)O)O.CCCCN(CCCC)CCCC.CCCCN(CCCC)CCCC.CCCCN(CCCC)CCCC.CCCCN(CCCC)CCCC	EC50 = 64200 nM	Poor binder
T93515	P2Y purinoceptor 2	B9AI7N	6-Propyl-3-beta-D-ribofuranosyl(1H)pyrimidine-2,4-dione 5''-monophosphate	Investigative	11993887	C12H19N2O9P	366.26	CCCC1=CC(=O)N(C(=O)N1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T93515	P2Y purinoceptor 2	BAJ0O1	[(2R,3S,5R)-5-[6-(Methylamino)purin-9-yl]-2-(phosphonooxymethyl)oxolan-3-yl] dihydrogen phosphate	Investigative	5311303	C11H17N5O9P2	425.23	CNC1=C2C(=NC=N1)N(C=N2)[C@H]3C[C@@H]([C@H](O3)COP(=O)(O)O)OP(=O)(O)O	EC50 ~ 100000 nM	Poor binder
T93515	P2Y purinoceptor 2	BB81PI	Trypan blue	Investigative	6296	C34H24N6Na4O14S4	960.8	CC1=C(C=CC(=C1)C2=CC(=C(C=C2)N=NC3=C(C4=C(C=C(C=C4C=C3S(=O)(=O)[O-])S(=O)(=O)[O-])N)O)C)N=NC5=C(C6=C(C=C(C=C6C=C5S(=O)(=O)[O-])S(=O)(=O)[O-])N)O.[Na+].[Na+].[Na+].[Na+]	IC50 = 171000 nM	Poor binder
T93515	P2Y purinoceptor 2	BCAH82	2-Benzylthio-1-beta-D-ribofuranosylpyrimidine-4-one-5''-monophosphate	Investigative	52952397	C16H19N2O8PS	430.4	C1=CC=C(C=C1)CSC2=NC(=O)C=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T93515	P2Y purinoceptor 2	BD4HU2	[(1R,2R,4S,5S)-4-[2-Chloro-6-(methylamino)purin-9-yl]-2-phosphonooxy-1-bicyclo[3.1.0]hexanyl]methyl dihydrogen phosphate	Investigative	76324375	C13H18ClN5O8P2	469.71	CNC1=C2C(=NC(=N1)Cl)N(C=N2)[C@H]3C[C@H]([C@]4([C@@H]3C4)COP(=O)(O)O)OP(=O)(O)O	EC50 ~ 100000 nM	Poor binder
T93515	P2Y purinoceptor 2	BE62TD	Chembl4215280	Investigative	145971828	C18H22ClNO5	367.8	CCCCCCOC1=CC2=C(C(=C1)Cl)C(=C(N2)C(=O)O)CCC(=O)O	EC50 ~ 50000 nM	Poor binder
T93515	P2Y purinoceptor 2	BG9AM0	CID 70694094	Investigative	70694094	C67H134BN11O20P4	1548.6	[B]P(=O)(OP(=O)(O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O)OP(=O)(O)OP(=O)(O)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=CC(=O)NC5=O)O)O.CCCCN(CCCC)CCCC.CCCCN(CCCC)CCCC.CCCCN(CCCC)CCCC.CCCCN(CCCC)CCCC	EC50 = 64200 nM	Poor binder
T93515	P2Y purinoceptor 2	BIH28N	N(3)-Methyluridine 5'-monophosphate	Investigative	44602426	C10H15N2O9P	338.21	CN1C(=O)C=CN(C1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T93515	P2Y purinoceptor 2	BJ4W0L	N,4-Dimethyl-N-(2-(thiophene-3-carbonyl)phenyl)benzenesulfonamide	Investigative	46225413	C19H17NO3S2	371.5	CC1=CC=C(C=C1)S(=O)(=O)N(C)C2=CC=CC=C2C(=O)C3=CSC=C3	IC50 ~ 60000 nM	Poor binder
T93515	P2Y purinoceptor 2	BQX4F5	Hexasodium;8-[[4-fluoro-3-[[3-[[3-[[2-fluoro-5-[(4,6,8-trisulfonatonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3,5-trisulfonate	Investigative	11636756	C49H28F2N6Na6O23S6	1437.1	C1=CC(=CC(=C1)NC(=O)NC2=CC=CC(=C2)C(=O)NC3=C(C=CC(=C3)C(=O)NC4=C5C(=CC(=CC5=C(C=C4)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])F)C(=O)NC6=C(C=CC(=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])F.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]	IC50 = 169824.37 nM	Poor binder
T93515	P2Y purinoceptor 2	BT7S5N	4-Thiouridine-5'-monophosphate	Investigative	16655024	C9H13N2O8PS	340.25	C1=CN(C(=O)NC1=S)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T93515	P2Y purinoceptor 2	BW5RX8	6-Methyl-3-beta-D-ribofuranosyl(1H)pyrimidine-2,4-dione 5''-monophosphate	Investigative	44417704	C10H15N2O9P	338.21	CC1=CC(=O)N(C(=O)N1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T93515	P2Y purinoceptor 2	BWZ3I1	[(4-Methylphenyl)sulfonyl](2-{[(4-methylphenyl)sulfonyl]prop-2-enylamino}pheny l)prop-2-enylamine	Investigative	3453336	C26H28N2O4S2	496.6	CC1=CC=C(C=C1)S(=O)(=O)N(CC=C)C2=CC=CC=C2N(CC=C)S(=O)(=O)C3=CC=C(C=C3)C	IC50 ~ 60000 nM	Poor binder
T93515	P2Y purinoceptor 2	BZA14G	n,n'-1,2-Phenylenebis(n,4-dimethylbenzenesulfonamide)	Investigative	265219	C22H24N2O4S2	444.6	CC1=CC=C(C=C1)S(=O)(=O)N(C)C2=CC=CC=C2N(C)S(=O)(=O)C3=CC=C(C=C3)C	IC50 ~ 60000 nM	Poor binder
T93515	P2Y purinoceptor 2	D01ZZJ	2-amino-uridine-5'-monophosphate	Investigative	49867142	C9H14N3O8P	323.2	C1=CN(C(=NC1=O)N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T93515	P2Y purinoceptor 2	D02HAL	Uridine-5'-Diphosphate	Investigative	6031	C9H14N2O12P2	404.16	C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)O)O)O	EC50 ~ 100000 nM	Poor binder
T93515	P2Y purinoceptor 2	D05NWF	adenosine diphosphate	Investigative	6022	C10H15N5O10P2	427.2	C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)O)O)O)N	EC50 ~ 100000 nM	Poor binder
T93515	P2Y purinoceptor 2	D0BB0O	2MeSADP	Investigative	121990	C11H17N5O10P2S	473.3	CSC1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)O)O)O)N	EC50 ~ 100000 nM	Poor binder
T93515	P2Y purinoceptor 2	D0P0EP	6-Hydroxyuridine-5'-Phosphate	Investigative	161647	C9H13N2O10P	340.18	C1=C(N(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O)O	EC50 ~ 100000 nM	Poor binder