TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T97035	Tyrosinase	B05XCP	1-[(Z)-2-(2,4-Dimethoxyphenyl)ethenyl]-3,5-dimethoxybenzene	Investigative	6604874	C18H20O4	300.3	COC1=CC(=C(C=C1)/C=C\\C2=CC(=CC(=C2)OC)OC)OC	IC50 ~ 100000 nM	Poor binder
T97035	Tyrosinase	B0P5KR	trans-2,3''-Dimethoxy-4,5''-dihydroxystilbene	Investigative	44419359	C16H16O4	272.29	COC1=CC(=CC(=C1)O)/C=C/C2=C(C=C(C=C2)O)OC	IC50 ~ 100000 nM	Poor binder
T97035	Tyrosinase	B18NRC	(8S,9R,10R,13R,14S,16R,17R)-17-[(2S)-2,6-Dihydroxy-6-methyl-3-oxoheptan-2-yl]-16-hydroxy-4,4,9,13,14-pentamethyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthrene-3,11-dione	Investigative	44584115	C36H54O12	678.8	C[C@@]12C[C@H]([C@@H]([C@]1(CC(=O)[C@@]3([C@H]2CC=C4[C@H]3C=C(C(=O)C4(C)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)C)C)[C@@](C)(C(=O)CCC(C)(C)O)O)O	IC50 = 85010 nM	Poor binder
T97035	Tyrosinase	B1WUI6	2,3',4,5'-Tetramethoxystilbene	Investigative	5354004	C18H20O4	300.3	COC1=CC(=C(C=C1)/C=C/C2=CC(=CC(=C2)OC)OC)OC	IC50 ~ 100000 nM	Poor binder
T97035	Tyrosinase	B2HZK7	Gnetucleistol D	Investigative	44419358	C15H14O4	258.269	COC1=C(C=CC(=C1)O)/C=C/C2=CC(=CC(=C2)O)O	IC50 ~ 100000 nM	Poor binder
T97035	Tyrosinase	B3KL1Y	Cyclosieversioside	Investigative	44406702	C41H68O14	785	C[C@]12CC[C@@]34C[C@@]35CC[C@@H](C([C@@H]5[C@H](C[C@H]4[C@@]1(C[C@@H]([C@@H]2[C@]6(CC[C@H](O6)C(C)(C)O)C)O)C)O[C@@H]7[C@H]([C@H]([C@H]([C@@H](O7)CO)O)O)O)(C)C)O[C@H]8[C@@H]([C@H]([C@@H](CO8)O)O)O	IC50 = 92250 nM	Poor binder
T97035	Tyrosinase	B7JN3I	1-Hydroxy-5-[(Z)-(4-hydroxy-3-oxo-1-benzofuran-2-ylidene)methyl]pyridin-2-one	Investigative	46864287	C14H9NO5	271.22	C1=CC(=C2C(=C1)O/C(=C\\C3=CN(C(=O)C=C3)O)/C2=O)O	IC50 = 120000 nM	Poor binder
T97035	Tyrosinase	B7OG3T	5-[(Z)-(4,6-Dihydroxy-3-oxo-1-benzofuran-2-ylidene)methyl]-1-hydroxypyridin-2-one	Investigative	134153783	C14H9NO6	287.22	C1=CC(=O)N(C=C1/C=C\\2/C(=O)C3=C(C=C(C=C3O2)O)O)O	IC50 = 119000 nM	Poor binder
T97035	Tyrosinase	B9AU6X	1-Hydroxy-5-[(Z)-(6-hydroxy-3-oxo-1-benzofuran-2-ylidene)methyl]pyridin-2-one	Investigative	46864286	C14H9NO5	271.22	C1=CC2=C(C=C1O)O/C(=C\\C3=CN(C(=O)C=C3)O)/C2=O	IC50 = 85300 nM	Poor binder
T97035	Tyrosinase	BF1Q0G	7H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinoline-7-carboxaldehyde,5,6,7a,8-tetrahydro-, (7aR)-	Investigative	158516	C18H15NO3	293.3	C1CN([C@@H]2CC3=CC=CC=C3C4=C2C1=CC5=C4OCO5)C=O	EC50 = 90000 nM	Poor binder
T97035	Tyrosinase	BG0V1S	4-Isopropylbenzaldehyde	Investigative	326	C10H12O	148.2	CC(C)C1=CC=C(C=C1)C=O	IC50 = 50000 nM	Poor binder
T97035	Tyrosinase	BI1HU5	Fortuneanoside D	Investigative	11844493	C20H24O10	424.4	COC1=CC(=CC(=C1O)OC)C2=C(C(=CC=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O	IC50 = 70000 nM	Poor binder
T97035	Tyrosinase	BL37QK	Cycloorbicoside G	Investigative	13943263	C41H66O14	783	C[C@@H]1C[C@@H]2[C@H](O[C@]3([C@H]1[C@]4(CC[C@@]56C[C@@]57CC[C@@H](C([C@@H]7C[C@@H]([C@H]6[C@@]4(C3)C)O)(C)C)O[C@H]8[C@@H]([C@H]([C@@H](CO8)O)O)O)C)O2)C(C)(C)O[C@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O)O	IC50 = 54640 nM	Poor binder
T97035	Tyrosinase	BQ3CL8	Fortuneanoside E	Investigative	11844494	C20H24O10	424.4	COC1=CC(=CC(=C1O)OC)C2=CC(=C(C=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O	IC50 = 140000 nM	Poor binder
T97035	Tyrosinase	BRL41B	2,4,3',5'-Tetramethoxybibenzyl	Investigative	44419367	C18H22O4	302.4	COC1=CC(=C(C=C1)CCC2=CC(=CC(=C2)OC)OC)OC	IC50 ~ 100000 nM	Poor binder
T97035	Tyrosinase	BU02GY	trans-4,3''-Dimethoxy-2,5''-dihydroxystilbene	Investigative	44419360	C16H16O4	272.29	COC1=CC(=C(C=C1)/C=C/C2=CC(=CC(=C2)OC)O)O	IC50 ~ 100000 nM	Poor binder
T97035	Tyrosinase	BWD20Y	Cyclocarposide	Investigative	21626605	C41H68O13	769	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@H]2C[C@H]3[C@@]4(C[C@@H]([C@@H]([C@]4(CC[C@]35C[C@]56[C@@H]2C([C@H](CC6)O[C@H]7[C@@H]([C@H]([C@@H](CO7)O)O)O)(C)C)C)[C@]8(CC[C@H](O8)C(C)(C)O)C)O)C)O)O)O	IC50 = 102390 nM	Poor binder
T97035	Tyrosinase	BXP83I	2-Hydroxypyridine 1-oxide	Investigative	69975	C5H5NO2	111.1	C1=CC(=O)N(C=C1)O	Ki = 128000 nM	Poor binder
T97035	Tyrosinase	D0DQ2G	2-tert-butylbenzene-1,4-diol	Investigative	16043	C10H14O2	166.22	CC(C)(C)C1=C(C=CC(=C1)O)O	IC50 = 54200 nM	Poor binder
T97035	Tyrosinase	D0J6RQ	1,5-bis(4-hydroxyphenyl)penta-1,4-dien-3-one	Investigative	6437306	C17H14O3	266.29	C1=CC(=CC=C1/C=C/C(=O)/C=C/C2=CC=C(C=C2)O)O	IC50 = 79050 nM	Poor binder