TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T97071	Glutamate carboxypeptidase II	B3R4HI	(R)-3-Acetylamino-N-hydroxy-succinamic acid	Investigative	44306373	C6H10N2O5	190.15	CC(=O)N[C@H](CC(=O)O)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T97071	Glutamate carboxypeptidase II	B53FQZ	(2S)-2-[[[(3R,5S)-1-[(4S)-4-(6-Aminohexanoylamino)-4-carboxybutanoyl]-5-carboxypyrrolidin-3-yl]oxy-hydroxyphosphoryl]amino]pentanedioic acid	Investigative	118737812	C21H35N4O13P	582.5	C1[C@H](CN([C@@H]1C(=O)O)C(=O)CC[C@@H](C(=O)O)NC(=O)CCCCCN)OP(=O)(N[C@@H](CCC(=O)O)C(=O)O)O	IC50 = 79000 nM	Poor binder
T97071	Glutamate carboxypeptidase II	B6Z5WJ	(2S)-2-[[[(3S,5R)-1-[(4S)-4-(6-Aminohexanoylamino)-4-carboxybutanoyl]-5-carboxypyrrolidin-3-yl]oxy-hydroxyphosphoryl]amino]pentanedioic acid	Investigative	118737813	C21H35N4O13P	582.5	C1[C@@H](CN([C@H]1C(=O)O)C(=O)CC[C@@H](C(=O)O)NC(=O)CCCCCN)OP(=O)(N[C@@H](CCC(=O)O)C(=O)O)O	IC50 = 112000 nM	Poor binder
T97071	Glutamate carboxypeptidase II	B90DJV	(2S)-2-[[[(3R,5S)-1-[(4S)-4-Amino-4-carboxybutanoyl]-5-carboxypyrrolidin-3-yl]oxy-hydroxyphosphoryl]amino]pentanedioic acid	Investigative	118737810	C15H24N3O12P	469.34	C1[C@H](CN([C@@H]1C(=O)O)C(=O)CC[C@@H](C(=O)O)N)OP(=O)(N[C@@H](CCC(=O)O)C(=O)O)O	IC50 = 60000 nM	Poor binder
T97071	Glutamate carboxypeptidase II	BEG5M1	N-Hydroxy-L-asparagine	Investigative	97663	C4H8N2O4	148.12	C([C@@H](C(=O)O)N)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T97071	Glutamate carboxypeptidase II	BLJ07K	n-Hydroxy-d-asparagine	Investigative	455017	C4H8N2O4	148.12	C([C@H](C(=O)O)N)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T97071	Glutamate carboxypeptidase II	BT5UF9	(S)-3-Acetylamino-N-hydroxy-succinamic acid	Investigative	44306478	C6H10N2O5	190.15	CC(=O)N[C@@H](CC(=O)O)C(=O)NO	IC50 ~ 100000 nM	Poor binder
T97071	Glutamate carboxypeptidase II	BWBV71	3-[2-(2-Benzoyloxymethyl-3-benzyl-4-oxo-azetidin-1-yl)-2-oxo-ethyl]-benzoic acid benzyl ester	Investigative	10530644	C34H29NO6	547.6	C1=CC=C(C=C1)C[C@H]2[C@H](N(C2=O)C(=O)CC3=CC(=CC=C3)C(=O)OCC4=CC=CC=C4)COC(=O)C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T97071	Glutamate carboxypeptidase II	BZ91FU	4-[(1-Benzoyl-3alpha-benzyl-4-oxoazetidine-2alpha-yl)methoxycarbonyl]benzoic acid	Investigative	10789375	C26H21NO6	443.4	C1=CC=C(C=C1)C[C@H]2[C@H](N(C2=O)C(=O)C3=CC=CC=C3)COC(=O)C4=CC=C(C=C4)C(=O)O	IC50 ~ 100000 nM	Poor binder
T97071	Glutamate carboxypeptidase II	D04SMQ	(S)-WILLARDIINE	Investigative	440053	C7H9N3O4	199.16	C1=CN(C(=O)NC1=O)C[C@@H](C(=O)O)N	IC50 = 67000 nM	Poor binder
T97071	Glutamate carboxypeptidase II	D0G9LM	Glutamine Hydroxamate	Investigative	449178	C5H10N2O4	162.14	C(CC(=O)NO)[C@@H](C(=O)O)N	IC50 ~ 100000 nM	Poor binder