TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T99989	Casein kinase I epsilon	B0PV8T	2-[4-[[5-[3-(Methoxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]benzonitrile	Investigative	57523093	C26H21N3O4S	471.5	COCC1COC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC=C5C#N	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	B1XKE7	CID 71578744	Investigative	71578744	C17H13N5O2S	351.4	CC(=O)NC1=NC=CC(=C1)C2=NN=C(O2)SCC3=CC(=CC=C3)C#N	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	B2TDR1	2-(1,3-Benzodioxol-5-yl)-5-[[4-(3,5-difluorophenyl)phenyl]methylsulfanyl]-1,3,4-oxadiazole	Investigative	71578446	C22H14F2N2O3S	424.4	C1OC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC(=CC(=C5)F)F	IC50 = 80000 nM	Poor binder
T99989	Casein kinase I epsilon	B3V9PA	2-[[4-(4-Methoxyphenyl)phenyl]methylsulfanyl]-5-pyridin-4-yl-1,3,4-oxadiazole	Investigative	71212403	C21H17N3O2S	375.4	COC1=CC=C(C=C1)C2=CC=C(C=C2)CSC3=NN=C(O3)C4=CC=NC=C4	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	B4FHT8	2-[[4-(3,5-Difluorophenyl)phenyl]methylsulfanyl]-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazole	Investigative	71212517	C23H16F2N2O3S	438.4	C1COC2=C(O1)C=CC(=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC(=CC(=C5)F)F	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	B5AST9	N-[4-[5-[[4-(2-Cyanophenyl)phenyl]methylsulfanyl]-1,3,4-oxadiazol-2-yl]pyridin-2-yl]acetamide	Investigative	71578745	C23H17N5O2S	427.5	CC(=O)NC1=NC=CC(=C1)C2=NN=C(O2)SCC3=CC=C(C=C3)C4=CC=CC=C4C#N	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	B6J8GD	3-[4-[(5-Pyridin-4-yl-1,3,4-oxadiazol-2-yl)sulfanylmethyl]phenyl]benzonitrile	Investigative	71212514	C21H14N4OS	370.4	C1=CC(=CC(=C1)C2=CC=C(C=C2)CSC3=NN=C(O3)C4=CC=NC=C4)C#N	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	B79YJF	2-[(4-Phenylphenyl)methylsulfanyl]-5-pyridin-4-yl-1,3,4-oxadiazole	Investigative	24370907	C20H15N3OS	345.4	C1=CC=C(C=C1)C2=CC=C(C=C2)CSC3=NN=C(O3)C4=CC=NC=C4	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	B7OY1C	2-[4-[(5-Pyridin-4-yl-1,3,4-oxadiazol-2-yl)sulfanylmethyl]phenyl]benzonitrile	Investigative	30291292	C21H14N4OS	370.4	C1=CC=C(C(=C1)C#N)C2=CC=C(C=C2)CSC3=NN=C(O3)C4=CC=NC=C4	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	B9HKQ6	N-[4-(5-Benzylsulfanyl-1,3,4-oxadiazol-2-yl)pyridin-2-yl]acetamide	Investigative	71578658	C16H14N4O2S	326.4	CC(=O)NC1=NC=CC(=C1)C2=NN=C(O2)SCC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	BCRO12	2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-[[4-(2-nitrophenyl)phenyl]methylsulfanyl]-1,3,4-oxadiazole	Investigative	71578307	C23H17N3O5S	447.5	C1COC2=C(O1)C=CC(=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC=C5[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	BD9GE4	2-[4-[[5-(1,3-Benzodioxol-5-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]-5-methoxybenzonitrile	Investigative	71212317	C24H17N3O4S	443.5	COC1=CC(=C(C=C1)C2=CC=C(C=C2)CSC3=NN=C(O3)C4=CC5=C(C=C4)OCO5)C#N	IC50 = 50000 nM	Poor binder
T99989	Casein kinase I epsilon	BEP25N	2-[[4-(2-Nitrophenyl)phenyl]methylsulfanyl]-5-pyridin-4-yl-1,3,4-oxadiazole	Investigative	71578447	C20H14N4O3S	390.4	C1=CC=C(C(=C1)C2=CC=C(C=C2)CSC3=NN=C(O3)C4=CC=NC=C4)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	BG1T9K	4-[4-[(5-Pyridin-4-yl-1,3,4-oxadiazol-2-yl)sulfanylmethyl]phenyl]benzonitrile	Investigative	71212434	C21H14N4OS	370.4	C1=CC(=CC=C1CSC2=NN=C(O2)C3=CC=NC=C3)C4=CC=C(C=C4)C#N	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	BHTK41	2-[4-[[5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]-5-methoxybenzonitrile	Investigative	71212446	C25H19N3O4S	457.5	COC1=CC(=C(C=C1)C2=CC=C(C=C2)CSC3=NN=C(O3)C4=CC5=C(C=C4)OCCO5)C#N	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	BIO5X9	2-(1,3-Benzodioxol-5-yl)-5-[[4-(3-nitrophenyl)phenyl]methylsulfanyl]-1,3,4-oxadiazole	Investigative	71578375	C22H15N3O5S	433.4	C1OC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC(=CC=C5)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	BJ69QM	2-(2H-1,3-Benzodioxol-5-yl)-5-[({[1,1'-biphenyl]-4-yl}methyl)sulfanyl]-1,3,4-oxadiazole	Investigative	7458031	C22H16N2O3S	388.4	C1OC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	BJM01F	4-[4-[[5-(1,3-Benzodioxol-5-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]benzonitrile	Investigative	57522818	C23H15N3O3S	413.4	C1OC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=C(C=C5)C#N	IC50 = 60000 nM	Poor binder
T99989	Casein kinase I epsilon	BK59PQ	2-(1,3-Benzodioxol-5-yl)-5-[[4-(2-nitrophenyl)phenyl]methylsulfanyl]-1,3,4-oxadiazole	Investigative	71578373	C22H15N3O5S	433.4	C1OC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC=C5[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	BMED31	2-[4-[[5-[(3R)-3-(Methoxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]benzonitrile	Investigative	57523094	C26H21N3O4S	471.5	COC[C@@H]1COC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC=C5C#N	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	BO02QN	2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-[[4-(4-methoxyphenyl)phenyl]methylsulfanyl]-1,3,4-oxadiazole	Investigative	71212395	C24H20N2O4S	432.5	COC1=CC=C(C=C1)C2=CC=C(C=C2)CSC3=NN=C(O3)C4=CC5=C(C=C4)OCCO5	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	BO0JH1	2-[4-[[5-[(3S)-3-(Methoxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]benzonitrile	Investigative	57523095	C26H21N3O4S	471.5	COC[C@H]1COC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC=C5C#N	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	BQV6B2	5-Fluoro-2-[4-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)sulfanylmethyl]phenyl]benzonitrile	Investigative	71578520	C21H13FN4OS	388.4	C1=CC(=CC=C1CSC2=NN=C(O2)C3=CC=NC=C3)C4=C(C=C(C=C4)F)C#N	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	BS0W8Z	2-[4-[[5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]benzonitrile	Investigative	57522819	C24H17N3O3S	427.5	C1COC2=C(O1)C=CC(=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC=C5C#N	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	BS1R6Q	2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-[[4-(3-nitrophenyl)phenyl]methylsulfanyl]-1,3,4-oxadiazole	Investigative	71212337	C23H17N3O5S	447.5	C1COC2=C(O1)C=CC(=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC(=CC=C5)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	BTS9M3	3-[4-[[5-(1,3-Benzodioxol-5-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]benzonitrile	Investigative	71578374	C23H15N3O3S	413.4	C1OC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC(=C5)C#N	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	BUK1D4	Methyl 4-[[5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]benzoate	Investigative	70694953	C19H16N2O5S	384.4	COC(=O)C1=CC=C(C=C1)CSC2=NN=C(O2)C3=CC4=C(C=C3)OCCO4	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	BVAM65	2-[4-[[5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]-5-fluorobenzonitrile	Investigative	57522820	C24H16FN3O3S	445.5	C1COC2=C(O1)C=CC(=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=C(C=C(C=C5)F)C#N	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	BWE0H2	3-[4-[[5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]benzonitrile	Investigative	71212291	C24H17N3O3S	427.5	C1COC2=C(O1)C=CC(=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC(=C5)C#N	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	BX80VR	2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-[(4-phenylphenyl)methylsulfanyl]-1,3,4-oxadiazole	Investigative	71212419	C23H18N2O3S	402.5	C1COC2=C(O1)C=CC(=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	BYQU48	4'-({[5-(2H-1,3-Benzodioxol-5-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}methyl)-[1,1'-biphenyl]-2-carbonitrile	Investigative	30291209	C23H15N3O3S	413.4	C1OC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC=C5C#N	IC50 ~ 100000 nM	Poor binder
T99989	Casein kinase I epsilon	BZM1D2	4-[4-[[5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]benzonitrile	Investigative	71212233	C24H17N3O3S	427.5	C1COC2=C(O1)C=CC(=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=C(C=C5)C#N	IC50 ~ 100000 nM	Poor binder