Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 61 68 0 1 0 999 V2000 0.3109 1.4837 0.0039 C 0 0 1 0 0 0 0 0 0 0 0 0 0.0849 0.0419 -0.1094 N 0 0 0 0 0 0 0 0 0 0 0 0 2.7445 0.6016 -1.8103 N 0 0 0 0 0 0 0 0 0 0 0 0 0.8961 -0.8263 -0.8244 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0581 -0.5842 -1.5664 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6778 1.8214 -0.0568 O 0 0 0 0 0 0 0 0 0 0 0 0 2.3433 1.9119 -1.2962 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7098 -1.6382 -2.2099 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3853 -2.1299 -0.7266 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1871 -2.9494 -2.1149 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0325 -3.1775 -1.3740 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9421 -0.6674 0.4666 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8403 0.3349 -2.5929 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.5240 2.2389 -1.0228 C 0 0 1 0 0 0 0 0 0 0 0 0 3.8690 -1.0507 -2.8751 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8082 -2.0290 0.1153 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5339 2.6721 -2.3396 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6385 -4.2313 -2.6780 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8085 -5.2225 -2.3111 N 0 0 0 0 0 0 0 0 0 0 0 0 0.1170 2.0916 -2.4074 C 0 0 1 0 0 0 0 0 0 0 0 0 0.7458 -4.6559 -1.4730 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6238 -4.3740 -3.3764 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.1984 1.9114 1.3818 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1800 0.6712 -2.7768 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.8473 1.7002 -1.0504 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.9947 -0.2442 1.2773 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8301 1.1812 -3.0915 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.7154 -2.9900 0.5607 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8797 -1.6144 -3.6565 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0451 0.2531 -3.4714 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.8547 2.6511 -1.4013 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.8851 -1.2121 1.7111 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8238 0.6035 -3.8632 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8499 -0.7528 -4.1387 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.7521 -2.5449 1.3646 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2559 2.4845 -1.1305 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5662 3.2939 -0.7521 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4824 3.7253 -2.0633 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0137 2.5746 -3.3134 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8972 -6.1562 -2.5587 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.4701 2.6388 -3.1449 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7680 -5.1093 -0.4821 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.2261 -4.8190 -1.9388 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0372 1.1376 2.1125 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2828 2.8450 1.6733 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2779 2.0563 1.3413 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9968 0.4792 -3.3372 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1108 0.7932 1.5544 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8221 2.2412 -2.8844 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.6149 -4.0310 0.2915 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9035 -2.6721 -3.8740 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9719 -0.8024 -3.7335 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.9037 0.4065 -2.8177 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.1686 0.8449 -4.3783 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.8539 3.4653 -0.6766 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.6486 3.0489 -2.3949 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.8300 2.1643 -1.3999 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.7111 -0.9165 2.3409 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6051 1.2324 -4.2638 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6495 -1.1498 -4.7465 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.4759 -3.2577 1.7311 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 6 1 0 0 0 0 1 14 1 0 0 0 0 1 23 1 0 0 0 0 2 4 1 0 0 0 0 2 12 1 0 0 0 0 3 7 1 0 0 0 0 3 13 1 0 0 0 0 3 5 1 0 0 0 0 4 5 1 0 0 0 0 4 9 2 0 0 0 0 5 8 2 0 0 0 0 6 7 1 0 0 0 0 7 17 1 0 0 0 0 7 36 1 0 0 0 0 8 15 1 0 0 0 0 8 10 1 0 0 0 0 9 11 1 0 0 0 0 9 16 1 0 0 0 0 10 11 2 0 0 0 0 10 18 1 0 0 0 0 11 21 1 0 0 0 0 12 16 2 0 0 0 0 12 26 1 0 0 0 0 13 15 2 0 0 0 0 13 27 1 0 0 0 0 14 20 1 0 0 0 0 14 25 1 0 0 0 0 14 37 1 0 0 0 0 15 29 1 0 0 0 0 16 28 1 0 0 0 0 17 20 1 0 0 0 0 17 38 1 0 0 0 0 17 39 1 0 0 0 0 18 22 2 0 0 0 0 18 19 1 0 0 0 0 19 21 1 0 0 0 0 19 40 1 0 0 0 0 20 24 1 0 0 0 0 20 41 1 0 0 0 0 21 42 1 0 0 0 0 21 43 1 0 0 0 0 23 44 1 0 0 0 0 23 45 1 0 0 0 0 23 46 1 0 0 0 0 24 30 1 0 0 0 0 24 47 1 0 0 0 0 25 31 1 0 0 0 0 26 32 2 0 0 0 0 26 48 1 0 0 0 0 27 33 2 0 0 0 0 27 49 1 0 0 0 0 28 35 2 0 0 0 0 28 50 1 0 0 0 0 29 34 2 0 0 0 0 29 51 1 0 0 0 0 30 52 1 0 0 0 0 30 53 1 0 0 0 0 30 54 1 0 0 0 0 31 55 1 0 0 0 0 31 56 1 0 0 0 0 31 57 1 0 0 0 0 32 35 1 0 0 0 0 32 58 1 0 0 0 0 33 34 1 0 0 0 0 33 59 1 0 0 0 0 34 60 1 0 0 0 0 35 61 1 0 0 0 0 M END > 186358 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 19397322 > J. Med. Chem.|2009|52|10|3191 > staurosporine > 2009 > 186358 > Serine/threonine-protein kinase Chk1 > Homo sapiens > 20022510 > Bioorg. Med. Chem.|2010|18|2|707 > Staurosporine > 2010 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 50 55 0 0 0 0 0 0 0 0999 V2000 -0.0168 1.3856 0.0097 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1326 2.0398 0.0022 N 0 0 0 0 0 0 0 0 0 0 0 0 2.2941 1.3971 -0.0123 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3650 0.0769 -0.0206 N 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2519 -0.6538 -0.0139 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9585 -2.0904 -0.0184 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3937 -2.2148 -0.0055 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.9706 -0.9803 0.0065 N 0 0 0 0 0 0 0 0 0 0 0 0 3.4690 2.1330 -0.0196 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.4136 -0.7279 0.0220 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.9084 -0.5082 -1.4091 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.3553 -0.2551 -1.3935 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1601 -8.8512 5.8738 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2537 -9.9746 5.0639 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4142 -9.8367 3.7048 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2271 -7.6024 5.3365 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3925 -7.4300 3.9440 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4853 -8.5643 3.1303 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6850 -8.0803 1.4511 S 0 0 0 0 0 0 0 0 0 0 0 0 2.6412 -6.3773 1.8641 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4867 -6.2025 3.1766 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7601 -5.2779 0.8843 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8410 -4.2377 0.8895 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9483 -3.1953 -0.0347 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9749 -3.1878 -0.9678 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8083 -5.2780 -0.0524 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9086 -4.2295 -0.9844 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0787 -4.5231 -1.8074 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5921 -5.6422 -1.3825 N 0 0 0 0 0 0 0 0 0 0 0 0 4.8483 -6.1320 -0.3041 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.9540 1.9221 0.0259 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9312 -3.1516 -0.0047 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4342 3.1024 -0.0141 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3259 1.6786 -0.0302 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.9278 -1.5851 0.4566 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.6207 0.1606 0.6184 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.3942 0.3490 -1.8437 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.7013 -1.3968 -2.0055 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.5794 0.5255 -0.7948 H 0 0 0 0 0 0 0 0 0 0 0 0 -4.7065 -0.1067 -2.3277 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0297 -8.9690 6.9394 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1995 -10.9602 5.5022 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4859 -10.7144 3.0795 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1537 -6.7375 5.9790 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4354 -5.2247 3.6323 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0382 -4.2343 1.6119 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0528 -2.3798 -1.6801 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4513 -3.9205 -2.6225 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0344 -6.9505 0.1821 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 1 0 0 0 0 1 2 2 0 0 0 0 1 32 1 0 0 0 0 2 3 1 0 0 0 0 3 10 1 0 0 0 0 3 4 2 0 0 0 0 4 6 1 0 0 0 0 5 9 1 0 0 0 0 5 6 2 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 7 25 1 0 0 0 0 8 9 1 0 0 0 0 8 33 1 0 0 0 0 9 11 1 0 0 0 0 10 34 1 0 0 0 0 10 35 1 0 0 0 0 11 12 1 0 0 0 0 11 36 1 0 0 0 0 11 37 1 0 0 0 0 12 13 1 0 0 0 0 12 38 1 0 0 0 0 12 39 1 0 0 0 0 13 40 1 0 0 0 0 13 41 1 0 0 0 0 14 15 2 0 0 0 0 14 17 1 0 0 0 0 14 42 1 0 0 0 0 15 16 1 0 0 0 0 15 43 1 0 0 0 0 16 19 2 0 0 0 0 16 44 1 0 0 0 0 17 18 2 0 0 0 0 17 45 1 0 0 0 0 18 22 1 0 0 0 0 18 19 1 0 0 0 0 19 20 1 0 0 0 0 20 21 1 0 0 0 0 21 22 2 0 0 0 0 21 23 1 0 0 0 0 22 46 1 0 0 0 0 23 27 2 0 0 0 0 23 24 1 0 0 0 0 24 25 2 0 0 0 0 24 47 1 0 0 0 0 25 26 1 0 0 0 0 26 28 2 0 0 0 0 26 48 1 0 0 0 0 27 28 1 0 0 0 0 27 31 1 0 0 0 0 28 29 1 0 0 0 0 29 30 2 0 0 0 0 29 49 1 0 0 0 0 30 31 1 0 0 0 0 31 50 1 0 0 0 0 M END > 690207 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 19926477 > Bioorg. Med. Chem. Lett.|2010|20|1|334 > 31a > 2010 > 690207 > Serine/threonine-protein kinase Chk1 > Homo sapiens > 19926477 > Bioorg. Med. Chem. Lett.|2010|20|1|334 > 31a > 2010 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 57 60 0 0 0 999 V2000 0.4110 1.4797 0.2578 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7727 2.2042 0.3847 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7367 3.5825 0.4199 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4767 4.2519 0.3287 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6597 3.5383 0.2021 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6339 2.1548 0.1723 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3754 -0.0013 0.2196 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3365 -0.7070 1.1902 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3742 -2.0828 1.1522 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2997 -2.7718 0.1419 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0116 -2.0650 -0.8294 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0490 -0.6893 -0.7902 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2600 -4.2494 0.1009 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3963 -5.0636 0.9758 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.1813 -6.3879 0.5738 N 0 0 0 0 0 0 0 0 0 0 0 0 0.5739 -6.3796 -0.5003 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8692 -5.0493 -0.8241 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0104 -7.5094 -1.2028 N 0 0 0 0 0 0 0 0 0 0 0 0 0.7394 -8.7874 -0.7081 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5831 -9.8544 -1.5840 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3153 -11.1165 -1.0915 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2026 -11.3188 0.2719 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3571 -10.2589 1.1466 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6312 -8.9954 0.6613 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7912 1.4546 0.0484 O 0 0 0 0 0 0 0 0 0 0 0 0 0.5047 5.6100 0.3574 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.0898 -12.6975 0.8056 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1736 -13.4050 1.0528 N 0 0 0 0 0 0 0 0 0 0 0 0 0.9272 -14.7558 1.5749 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1195 -15.6558 1.2442 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7431 -14.6902 3.0924 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.7180 1.6866 0.4552 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.6548 4.1428 0.5183 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6009 4.0625 0.1265 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8577 -0.1740 1.9716 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9247 -2.6290 1.9039 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5333 -2.5975 -1.6109 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5996 -0.1425 -1.5414 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9189 -4.7766 1.7409 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4705 -4.7154 -1.6568 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5010 -7.4047 -2.0331 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6707 -9.6970 -2.6489 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1933 -11.9463 -1.7719 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2681 -10.4204 2.2107 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7518 -8.1681 1.3450 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2080 1.2313 0.8919 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4309 6.0234 -0.5137 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6486 -12.6153 1.7378 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6800 -13.2520 0.0759 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7391 -13.4377 0.2177 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0261 -15.1636 1.1168 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0206 -15.2480 1.7023 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9366 -16.6581 1.6317 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2506 -15.7025 0.1632 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6442 -14.2825 3.5504 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.1063 -14.0491 3.3279 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5602 -15.6925 3.4798 H 0 0 0 0 0 0 0 0 0 0 0 0 1 7 1 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 2 3 1 0 0 0 0 2 32 1 0 0 0 0 3 4 2 0 0 0 0 3 33 1 0 0 0 0 4 5 1 0 0 0 0 4 26 1 0 0 0 0 5 6 2 0 0 0 0 5 34 1 0 0 0 0 6 25 1 0 0 0 0 7 8 2 0 0 0 0 7 12 1 0 0 0 0 8 9 1 0 0 0 0 8 35 1 0 0 0 0 9 10 2 0 0 0 0 9 36 1 0 0 0 0 10 11 1 0 0 0 0 10 13 1 0 0 0 0 11 12 2 0 0 0 0 11 37 1 0 0 0 0 12 38 1 0 0 0 0 13 17 2 0 0 0 0 13 14 1 0 0 0 0 14 15 1 0 0 0 0 14 39 1 0 0 0 0 15 16 2 0 0 0 0 16 17 1 0 0 0 0 16 18 1 0 0 0 0 17 40 1 0 0 0 0 18 19 1 0 0 0 0 18 41 1 0 0 0 0 19 20 2 0 0 0 0 19 24 1 0 0 0 0 20 21 1 0 0 0 0 20 42 1 0 0 0 0 21 22 2 0 0 0 0 21 43 1 0 0 0 0 22 23 1 0 0 0 0 22 27 1 0 0 0 0 23 24 2 0 0 0 0 23 44 1 0 0 0 0 24 45 1 0 0 0 0 25 46 1 0 0 0 0 26 47 1 0 0 0 0 27 28 1 0 0 0 0 27 48 1 0 0 0 0 27 49 1 0 0 0 0 28 29 1 0 0 0 0 28 50 1 0 0 0 0 29 30 1 0 0 0 0 29 31 1 0 0 0 0 29 51 1 0 0 0 0 30 52 1 0 0 0 0 30 53 1 0 0 0 0 30 54 1 0 0 0 0 31 55 1 0 0 0 0 31 56 1 0 0 0 0 31 57 1 0 0 0 0 M END > 505137 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 17887663 > J. Med. Chem.|2007|50|22|5253 > 10a > 2007 > 505137 > Serine/threonine-protein kinase Chk1 > Homo sapiens > 17887663 > J. Med. Chem.|2007|50|22|5253 > 10a > 2007 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 50 54 0 0 0 0 0 0 0 0999 V2000 -0.0161 1.3391 0.0094 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4228 1.8079 -0.0018 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.0024 2.0449 0.0271 O 0 0 0 0 0 0 0 0 0 0 0 0 1.3030 -0.5155 -0.0132 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2286 0.5281 -0.0150 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5807 0.2851 -0.0256 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7560 -1.8265 -0.0262 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1278 -2.0855 -0.0386 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0496 -1.0252 -0.0351 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3084 -1.5798 -0.0404 N 0 0 0 0 0 0 0 0 0 0 0 0 5.3488 -6.2138 -0.0605 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2189 -2.9625 -0.0434 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9189 -3.3239 -0.0568 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3265 -4.6978 -0.0821 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1289 -5.7217 0.6650 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4835 -5.2378 -0.0379 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4158 -3.8363 -0.0359 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6561 -3.3702 -0.0220 N 0 0 0 0 0 0 0 0 0 0 0 0 8.5318 -4.4602 -0.0089 N 0 0 0 0 0 0 0 0 0 0 0 0 7.7948 -5.5889 -0.0173 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3330 -6.9965 -0.0052 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2029 -0.8372 0.0091 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.6086 -1.1350 1.4540 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7076 2.6331 -1.2583 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7308 2.6219 1.2565 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2785 1.1094 -0.0270 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0501 -2.6439 -0.0267 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1376 -1.0764 -0.0424 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6786 -7.1447 0.4007 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0813 -6.4156 -1.0978 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3282 -4.6536 0.3533 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2353 -5.0177 -1.1201 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4859 -6.5758 0.8773 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4437 -5.2877 1.6140 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5005 -4.4125 0.0038 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4472 -7.3329 1.0253 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6395 -7.6552 -0.5277 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3018 -7.0193 -0.5043 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0128 -0.3091 -0.4942 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0006 -1.7731 -0.5117 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7987 -1.6632 1.9572 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.8109 -0.1991 1.9748 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.5051 -1.7549 1.4592 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4385 2.0543 -2.1419 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1192 3.5502 -1.2317 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7679 2.8826 -1.2965 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7917 2.8712 1.2773 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1421 3.5392 1.2489 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4781 2.0352 2.1397 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 1 0 0 0 0 1 2 1 0 0 0 0 1 4 2 0 0 0 0 2 6 1 0 0 0 0 2 25 1 0 0 0 0 2 26 1 0 0 0 0 3 5 1 0 0 0 0 3 23 1 0 0 0 0 5 6 2 0 0 0 0 5 8 1 0 0 0 0 6 7 1 0 0 0 0 7 10 2 0 0 0 0 7 27 1 0 0 0 0 8 9 2 0 0 0 0 8 28 1 0 0 0 0 9 10 1 0 0 0 0 9 14 1 0 0 0 0 10 11 1 0 0 0 0 11 13 1 0 0 0 0 11 29 1 0 0 0 0 12 17 1 0 0 0 0 12 16 1 0 0 0 0 12 30 1 0 0 0 0 12 31 1 0 0 0 0 13 18 1 0 0 0 0 13 14 2 0 0 0 0 14 15 1 0 0 0 0 15 16 1 0 0 0 0 15 32 1 0 0 0 0 15 33 1 0 0 0 0 16 34 1 0 0 0 0 16 35 1 0 0 0 0 17 18 1 0 0 0 0 17 21 2 0 0 0 0 18 19 2 0 0 0 0 19 20 1 0 0 0 0 20 21 1 0 0 0 0 20 36 1 0 0 0 0 21 22 1 0 0 0 0 22 37 1 0 0 0 0 22 38 1 0 0 0 0 22 39 1 0 0 0 0 23 24 1 0 0 0 0 23 40 1 0 0 0 0 23 41 1 0 0 0 0 24 42 1 0 0 0 0 24 43 1 0 0 0 0 24 44 1 0 0 0 0 25 45 1 0 0 0 0 25 46 1 0 0 0 0 25 47 1 0 0 0 0 26 48 1 0 0 0 0 26 49 1 0 0 0 0 26 50 1 0 0 0 0 M END > 589011 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 18630890 > J. Med. Chem.|2008|51|15|4465 > "32, AKI-001" > 2008 > 589011 > Serine/threonine-protein kinase Chk1 > Homo sapiens > 18630890 > J. Med. Chem.|2008|51|15|4465 > "32, AKI-001" > 2008 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 47 49 0 0 0 999 V2000 0.5930 1.5808 -0.6589 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5472 0.2048 -0.4855 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7904 2.2941 -1.1320 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.5840 1.4741 0.0627 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.0447 -0.1322 0.0720 S 0 0 0 0 0 0 0 0 0 0 0 0 -0.6063 2.2236 -0.3476 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9728 2.4876 -2.4116 N 0 0 0 0 0 0 0 0 0 0 0 0 1.5656 -0.7032 -0.7131 N 0 0 0 0 0 0 0 0 0 0 0 0 2.7201 2.7582 -0.2249 N 0 0 0 0 0 0 0 0 0 0 0 0 0.5686 -6.1276 -0.3376 O 0 0 0 0 0 0 0 0 0 0 0 0 1.3130 -2.0763 -0.6176 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7413 3.5705 -0.4597 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8136 -4.7934 -0.4295 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1177 3.2740 -2.8776 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5455 -6.9218 0.1736 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1157 -2.5972 -1.0914 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2618 -2.9198 -0.0542 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0120 -4.2746 0.0392 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1325 -3.9522 -0.9972 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1767 2.1625 -5.0228 O 0 0 0 0 0 0 0 0 0 0 0 0 3.9487 2.4368 -3.8520 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7267 -7.0043 1.5469 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3600 -7.6563 -0.6765 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6163 4.5336 -3.5868 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7205 -7.8124 2.0639 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3524 -8.4629 -0.1543 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5348 -8.5385 1.2143 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4547 -0.3882 -0.9390 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5228 2.7390 0.7247 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5712 3.1038 -0.5365 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5052 4.0575 0.3417 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7345 3.5581 -2.0251 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6210 -1.9425 -1.5330 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1948 -2.5162 0.3104 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7496 -4.9305 0.4776 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0650 -4.3569 -1.3621 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6420 1.6342 -5.6858 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8470 2.9880 -4.1299 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2314 1.4983 -3.3750 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0914 -6.4369 2.2109 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2179 -7.5976 -1.7455 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9995 4.2495 -4.4394 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0243 5.1301 -2.8927 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4681 5.1187 -3.9335 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8619 -7.8770 3.1326 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9863 -9.0350 -0.8155 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3114 -9.1694 1.6205 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 3 1 0 0 0 0 1 6 1 0 0 0 0 2 5 1 0 0 0 0 2 8 1 0 0 0 0 3 7 2 0 0 0 0 3 9 1 0 0 0 0 4 6 2 0 0 0 0 4 5 1 0 0 0 0 6 12 1 0 0 0 0 7 14 1 0 0 0 0 8 11 1 0 0 0 0 8 28 1 0 0 0 0 9 29 1 0 0 0 0 9 30 1 0 0 0 0 10 13 1 0 0 0 0 10 15 1 0 0 0 0 11 16 1 0 0 0 0 11 17 2 0 0 0 0 12 31 1 0 0 0 0 13 19 1 0 0 0 0 13 18 2 0 0 0 0 14 21 1 0 0 0 0 14 24 1 0 0 0 0 14 32 1 0 0 0 0 15 22 1 0 0 0 0 15 23 2 0 0 0 0 16 19 2 0 0 0 0 16 33 1 0 0 0 0 17 18 1 0 0 0 0 17 34 1 0 0 0 0 18 35 1 0 0 0 0 19 36 1 0 0 0 0 20 21 1 0 0 0 0 20 37 1 0 0 0 0 21 38 1 0 0 0 0 21 39 1 0 0 0 0 22 25 2 0 0 0 0 22 40 1 0 0 0 0 23 26 1 0 0 0 0 23 41 1 0 0 0 0 24 42 1 0 0 0 0 24 43 1 0 0 0 0 24 44 1 0 0 0 0 25 27 1 0 0 0 0 25 45 1 0 0 0 0 26 27 2 0 0 0 0 26 46 1 0 0 0 0 27 47 1 0 0 0 0 M END > 463000 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 16934458 > Bioorg. Med. Chem. Lett.|2006|16|21|5561 > 9 > 2006 > 463000 > Serine/threonine-protein kinase Chk2 > Homo sapiens > 16934458 > Bioorg. Med. Chem. Lett.|2006|16|21|5561 > 9 > 2006 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 48 50 0 0 0 999 V2000 2.3225 -2.5856 3.4880 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0113 -1.3904 3.5868 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4395 -0.7420 2.4453 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1780 -1.2918 1.1964 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4862 -2.4929 1.1009 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0606 -3.1357 2.2465 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6093 -0.6384 0.0396 N 0 0 0 0 0 0 0 0 0 0 0 0 4.7612 0.1560 0.0727 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7901 -0.1491 0.9546 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9286 0.6311 0.9832 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0453 1.7211 0.1302 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0162 2.0264 -0.7513 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8779 1.2460 -0.7803 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1998 2.5122 0.1593 N 0 0 0 0 0 0 0 0 0 0 0 0 9.4270 1.9351 0.4318 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7730 0.2606 0.6183 S 0 0 0 0 0 0 0 0 0 0 0 0 11.4305 0.4500 0.9153 N 0 0 0 0 0 0 0 0 0 0 0 0 11.7034 1.7187 0.8743 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6412 2.5837 0.6065 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7926 4.0457 0.5274 C 0 0 0 0 0 0 0 0 0 0 0 0 10.6386 4.8173 1.6603 N 0 0 0 0 0 0 0 0 0 0 0 0 11.0729 4.6127 -0.6163 N 0 0 0 0 0 0 0 0 0 0 0 0 10.7893 6.2724 1.5816 C 0 0 0 0 0 0 0 0 0 0 0 0 9.4619 6.9001 1.1516 C 0 0 0 0 0 0 0 0 0 0 0 0 11.1910 6.8185 2.9532 C 0 0 0 0 0 0 0 0 0 0 0 0 12.9641 2.1819 1.0770 O 0 0 0 0 0 0 0 0 0 0 0 0 10.1288 6.5982 3.8833 O 0 0 0 0 0 0 0 0 0 0 0 0 1.9924 -3.0927 4.3825 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2142 -0.9636 4.5579 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9768 0.1917 2.5232 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2816 -2.9233 0.1317 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5227 -4.0694 2.1730 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1105 -0.7352 -0.7867 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6992 -0.9964 1.6181 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7285 0.3942 1.6692 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1066 2.8744 -1.4140 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0798 1.4805 -1.4691 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1392 3.4651 -0.0116 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4305 4.3965 2.5092 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1727 5.5761 -0.6684 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5609 6.5188 0.8522 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1757 6.5110 0.1744 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6903 6.6537 1.8810 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5740 7.9827 1.0930 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0890 6.3066 3.2993 H 0 0 0 0 0 0 0 0 0 0 0 0 11.3895 7.8874 2.8748 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4915 2.2535 0.2696 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3146 6.9202 4.7760 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 6 1 0 0 0 0 1 28 1 0 0 0 0 2 3 1 0 0 0 0 2 29 1 0 0 0 0 3 4 2 0 0 0 0 3 30 1 0 0 0 0 4 7 1 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 5 31 1 0 0 0 0 6 32 1 0 0 0 0 7 8 1 0 0 0 0 7 33 1 0 0 0 0 8 13 1 0 0 0 0 8 9 2 0 0 0 0 9 10 1 0 0 0 0 9 34 1 0 0 0 0 10 11 2 0 0 0 0 10 35 1 0 0 0 0 11 14 1 0 0 0 0 11 12 1 0 0 0 0 12 13 2 0 0 0 0 12 36 1 0 0 0 0 13 37 1 0 0 0 0 14 15 1 0 0 0 0 14 38 1 0 0 0 0 15 16 1 0 0 0 0 15 19 2 0 0 0 0 16 17 1 0 0 0 0 17 18 2 0 0 0 0 18 19 1 0 0 0 0 18 26 1 0 0 0 0 19 20 1 0 0 0 0 20 21 1 0 0 0 0 20 22 2 0 0 0 0 21 23 1 0 0 0 0 21 39 1 0 0 0 0 22 40 1 0 0 0 0 23 24 1 0 0 0 0 23 25 1 0 0 0 0 23 41 1 0 0 0 0 24 42 1 0 0 0 0 24 43 1 0 0 0 0 24 44 1 0 0 0 0 25 27 1 0 0 0 0 25 45 1 0 0 0 0 25 46 1 0 0 0 0 26 47 1 0 0 0 0 27 48 1 0 0 0 0 M END > 520330 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 16934458 > Bioorg. Med. Chem. Lett.|2006|16|21|5561 > 10 > 2006 > 520330 > Serine/threonine-protein kinase Chk2 > Homo sapiens > 17035018 > Bioorg. Med. Chem. Lett.|2007|17|1|172 > 8 > 2007 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 72 77 0 0 0 999 V2000 1.3561 2.4411 0.2856 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6409 2.9715 0.4252 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7461 2.1235 0.4467 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1767 1.0849 0.1520 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6652 -0.0971 0.4168 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5698 0.7552 0.3293 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2814 0.2242 0.1546 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0836 -1.2125 -0.0553 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7444 -2.1836 0.5529 N 0 0 0 0 0 0 0 0 0 0 0 0 3.7336 -2.0454 1.5253 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7064 -1.0559 1.4379 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7075 -0.9799 2.3968 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7216 -1.8671 3.4567 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7382 -2.8327 3.5625 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7488 -2.9246 2.6026 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2348 -1.5418 -0.8613 O 0 0 0 0 0 0 0 0 0 0 0 0 2.8283 4.4361 0.5499 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1107 4.9668 0.6831 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2856 6.3307 0.7939 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1857 7.1778 0.7732 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9005 6.6517 0.6398 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7219 5.2862 0.5285 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8238 7.4826 0.6201 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.4621 6.8750 0.4806 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3662 8.5587 0.8867 N 0 0 0 0 0 0 0 0 0 0 0 0 4.7453 -3.7878 4.7281 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9415 -3.2036 5.8611 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4147 -2.1184 5.7346 O 0 0 0 0 0 0 0 0 0 0 0 0 3.8081 -3.8870 7.0151 N 0 0 0 0 0 0 0 0 0 0 0 0 3.1440 -3.3032 8.1025 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0535 -2.4718 7.8848 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3992 -1.8965 8.9559 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8316 -2.1499 10.2511 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9222 -2.9820 10.4687 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5732 -3.5609 9.3976 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1691 -1.5668 11.3365 N 0 0 0 0 0 0 0 0 0 0 0 0 1.7884 -1.9667 12.6085 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0720 -1.2609 13.7628 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3221 -1.5769 13.7164 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.9573 -1.2005 12.4916 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2614 -1.9056 11.3244 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4997 3.0991 0.2870 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7395 2.5331 0.5544 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1805 0.6818 0.0451 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3923 -0.0288 -0.2217 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5155 -3.0901 0.2946 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4768 -0.2264 2.3142 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5006 -1.8056 4.2022 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9838 -3.6821 2.6895 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9677 4.3097 0.6997 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2796 6.7401 0.8973 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7277 4.8774 0.4248 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6338 6.1928 1.3132 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.2308 7.6477 0.4796 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5024 6.3211 -0.4572 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2595 8.9250 0.9798 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5981 9.1510 0.8723 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3057 -4.7373 4.4225 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7714 -3.9517 5.0573 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1716 -4.7829 7.0930 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7172 -2.2747 6.8776 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5514 -1.2493 8.7865 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2589 -3.1788 11.4758 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4211 -4.2081 9.5668 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7017 -3.0462 12.7319 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8409 -1.6834 12.6057 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4902 -1.5980 14.7112 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2042 -0.1831 13.6686 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.0066 -1.4939 12.5207 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.8840 -0.1209 12.3604 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.7052 -1.5777 10.3844 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.3809 -2.9842 11.4274 H 0 0 0 0 0 0 0 0 0 0 0 0 1 4 1 0 0 0 0 1 2 2 0 0 0 0 1 42 1 0 0 0 0 2 3 1 0 0 0 0 2 17 1 0 0 0 0 3 6 2 0 0 0 0 3 43 1 0 0 0 0 4 7 2 0 0 0 0 4 44 1 0 0 0 0 5 11 1 0 0 0 0 5 6 1 0 0 0 0 5 45 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 8 16 2 0 0 0 0 8 9 1 0 0 0 0 9 10 1 0 0 0 0 9 46 1 0 0 0 0 10 11 2 0 0 0 0 10 15 1 0 0 0 0 11 12 1 0 0 0 0 12 13 2 0 0 0 0 12 47 1 0 0 0 0 13 14 1 0 0 0 0 13 48 1 0 0 0 0 14 26 1 0 0 0 0 14 15 2 0 0 0 0 15 49 1 0 0 0 0 17 22 1 0 0 0 0 17 18 2 0 0 0 0 18 19 1 0 0 0 0 18 50 1 0 0 0 0 19 20 2 0 0 0 0 19 51 1 0 0 0 0 20 21 1 0 0 0 0 20 25 1 0 0 0 0 21 22 2 0 0 0 0 21 23 1 0 0 0 0 22 52 1 0 0 0 0 23 24 1 0 0 0 0 24 53 1 0 0 0 0 24 54 1 0 0 0 0 24 55 1 0 0 0 0 25 56 1 0 0 0 0 25 57 1 0 0 0 0 26 27 1 0 0 0 0 26 58 1 0 0 0 0 26 59 1 0 0 0 0 27 28 2 0 0 0 0 27 29 1 0 0 0 0 29 30 1 0 0 0 0 29 60 1 0 0 0 0 30 31 2 0 0 0 0 30 35 1 0 0 0 0 31 32 1 0 0 0 0 31 61 1 0 0 0 0 32 33 2 0 0 0 0 32 62 1 0 0 0 0 33 34 1 0 0 0 0 33 36 1 0 0 0 0 34 35 2 0 0 0 0 34 63 1 0 0 0 0 35 64 1 0 0 0 0 36 37 1 0 0 0 0 36 41 1 0 0 0 0 37 38 1 0 0 0 0 37 65 1 0 0 0 0 37 66 1 0 0 0 0 38 39 1 0 0 0 0 38 67 1 0 0 0 0 38 68 1 0 0 0 0 39 40 1 0 0 0 0 40 41 1 0 0 0 0 40 69 1 0 0 0 0 40 70 1 0 0 0 0 41 71 1 0 0 0 0 41 72 1 0 0 0 0 M END > 487627 > Serine/threonine-protein kinase Aurora-B > Homo sapiens > 17658776 > J. Med. Chem.|2007|50|17|4162 > 46c > 2007 > 487627 > Serine/threonine-protein kinase Chk2 > Homo sapiens > 17658776 > J. Med. Chem.|2007|50|17|4162 > 46c > 2007 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 62 67 0 0 0 0 0 0 0 0999 V2000 -0.0187 1.5258 0.0104 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4167 2.0553 -0.0004 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1567 1.5485 1.2391 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1775 0.0187 1.2307 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7421 -0.5109 1.2415 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0021 -0.0041 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3973 3.4842 0.0074 O 0 0 0 0 0 0 0 0 0 0 0 0 0.7619 -1.9757 1.2335 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.2819 -2.6666 1.7331 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2619 -4.1434 1.7249 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.2400 -2.0742 2.1904 O 0 0 0 0 0 0 0 0 0 0 0 0 -1.3431 -4.8620 2.2424 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8535 -6.2020 1.1870 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8354 -4.8264 1.1948 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2248 -6.9216 1.7101 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.3210 -6.2373 2.2332 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.3185 -7.2643 2.7115 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.4551 -8.3835 1.8221 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.7052 -8.6113 2.4201 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.8921 -9.9576 2.5113 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7875 -10.5609 1.9840 N 0 0 0 0 0 0 0 0 0 0 0 0 0.0924 -9.5568 1.5619 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.0754 -10.6404 3.0779 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.6464 -11.7221 2.4049 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.7478 -12.3576 2.9332 C 0 0 0 0 0 0 0 0 0 0 0 0 -5.2932 -11.9206 4.1404 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.7234 -10.8395 4.8132 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.6183 -10.2071 4.2890 C 0 0 0 0 0 0 0 0 0 0 0 0 -6.4794 -12.6050 4.7085 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.0261 -12.1696 5.9151 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.1327 -12.8047 6.4379 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.7023 -13.8770 5.7645 C 0 0 0 0 0 0 0 0 0 0 0 0 -8.1604 -14.3130 4.5629 C 0 0 0 0 0 0 0 0 0 0 0 0 -7.0541 -13.6818 4.0345 C 0 0 0 0 0 0 0 0 0 0 0 0 -9.7922 -14.5013 6.2828 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.5289 1.8773 0.9072 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.5459 1.8868 -0.8726 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9269 1.7038 -0.8972 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1793 1.9258 1.2314 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6465 1.9000 2.1359 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6876 -0.3328 0.3339 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7046 -0.3424 2.1137 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2319 -0.1594 2.1383 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.0205 -0.3814 0.0098 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5123 -0.3556 -0.8948 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9431 3.8756 -0.7512 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5264 -2.4484 0.8686 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.1952 -4.3379 2.6495 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7026 -6.7272 0.7751 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6705 -4.2738 0.7901 H 0 0 0 0 0 0 0 0 0 0 0 0 -2.4872 -7.1528 3.7826 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.2582 -7.1550 2.1700 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.6381 -11.5167 1.9142 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.2246 -12.0601 1.4699 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.1896 -13.1944 2.4127 H 0 0 0 0 0 0 0 0 0 0 0 0 -5.1464 -10.5014 5.7476 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.1772 -9.3701 4.8100 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.5830 -11.3360 6.4397 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.5566 -12.4679 7.3724 H 0 0 0 0 0 0 0 0 0 0 0 0 -8.6058 -15.1473 4.0414 H 0 0 0 0 0 0 0 0 0 0 0 0 -6.6332 -14.0212 3.0995 H 0 0 0 0 0 0 0 0 0 0 0 0 -10.6351 -14.1259 5.9935 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 1 0 0 0 0 1 36 1 0 0 0 0 1 37 1 0 0 0 0 2 3 1 0 0 0 0 2 7 1 0 0 0 0 2 38 1 0 0 0 0 3 4 1 0 0 0 0 3 39 1 0 0 0 0 3 40 1 0 0 0 0 4 5 1 0 0 0 0 4 41 1 0 0 0 0 4 42 1 0 0 0 0 5 6 1 0 0 0 0 5 8 1 0 0 0 0 5 43 1 0 0 0 0 6 44 1 0 0 0 0 6 45 1 0 0 0 0 7 46 1 0 0 0 0 8 9 1 0 0 0 0 8 47 1 0 0 0 0 9 10 1 0 0 0 0 9 11 2 0 0 0 0 10 12 1 0 0 0 0 10 14 2 0 0 0 0 12 16 2 0 0 0 0 12 48 1 0 0 0 0 13 15 2 0 0 0 0 13 14 1 0 0 0 0 13 49 1 0 0 0 0 14 50 1 0 0 0 0 15 18 1 0 0 0 0 15 16 1 0 0 0 0 16 17 1 0 0 0 0 17 19 1 0 0 0 0 17 51 1 0 0 0 0 17 52 1 0 0 0 0 18 19 1 0 0 0 0 18 22 2 0 0 0 0 19 20 2 0 0 0 0 20 21 1 0 0 0 0 20 23 1 0 0 0 0 21 22 1 0 0 0 0 21 53 1 0 0 0 0 23 24 2 0 0 0 0 23 28 1 0 0 0 0 24 25 1 0 0 0 0 24 54 1 0 0 0 0 25 26 2 0 0 0 0 25 55 1 0 0 0 0 26 27 1 0 0 0 0 26 29 1 0 0 0 0 27 28 2 0 0 0 0 27 56 1 0 0 0 0 28 57 1 0 0 0 0 29 30 2 0 0 0 0 29 34 1 0 0 0 0 30 31 1 0 0 0 0 30 58 1 0 0 0 0 31 32 2 0 0 0 0 31 59 1 0 0 0 0 32 33 1 0 0 0 0 32 35 1 0 0 0 0 33 34 2 0 0 0 0 33 60 1 0 0 0 0 34 61 1 0 0 0 0 35 62 1 0 0 0 0 M END > 491822 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 17287122 > Bioorg. Med. Chem.|2007|15|7|2759 > 41 > 2007 > 491822 > Serine/threonine-protein kinase Chk1 > Homo sapiens > 20000735 > J. Med. Chem.|2010|53|7|2681 > 14 > 2010 $$$$ Wcorina 11010612233D 1 1.00000 0.00000 0 CORINA evaluation license 3.40 0067 02.08.2006 45 46 0 0 0 999 V2000 0.1645 1.3756 0.5343 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2578 0.0310 0.5358 N 0 0 0 0 0 0 0 0 0 0 0 0 1.0290 3.5094 -0.0734 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1757 2.1206 0.0456 N 0 0 0 0 0 0 0 0 0 0 0 0 -4.4650 -3.6716 3.3758 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1527 4.3322 -0.0781 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.7366 -0.7340 1.1344 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.7272 -0.1398 1.7877 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.6361 -2.8522 1.6090 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.6526 -3.0460 2.8868 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.2354 4.0672 -0.1925 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.6285 -2.2575 2.2703 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3950 3.7898 0.0324 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.8339 1.9162 0.9691 O 0 0 0 0 0 0 0 0 0 0 0 0 2.0024 5.7044 -0.1959 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6954 -2.1267 1.0429 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.6721 -0.8655 2.3565 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3776 5.4379 -0.3098 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4918 4.6985 0.1475 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9937 3.8410 2.3858 N 0 0 0 0 0 0 0 0 0 0 0 0 5.5636 4.0918 1.0553 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7392 6.2549 -0.3081 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.9605 6.1349 -0.4588 Cl 0 0 0 0 0 0 0 0 0 0 0 0 5.9131 3.0462 3.2110 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6422 5.1011 3.0541 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0853 4.9598 -1.2382 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0188 -0.4028 0.1193 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0051 1.6957 -0.2238 H 0 0 0 0 0 0 0 0 0 0 0 0 -1.1084 3.4314 -0.1941 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8724 6.3443 -0.1997 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1088 -2.6087 0.5068 H 0 0 0 0 0 0 0 0 0 0 0 0 -3.4781 -0.3820 2.8885 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1420 5.6378 0.5759 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9134 3.1526 0.6269 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4002 4.7850 1.1432 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6241 7.3248 -0.3995 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8532 3.5850 3.3294 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4666 2.8751 4.1905 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1017 2.0887 2.7255 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9068 5.6375 2.4544 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2226 4.8864 4.0369 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5362 5.7143 3.1667 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3218 5.3920 -1.8849 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9220 5.6529 -1.1504 H 0 0 0 0 0 0 0 0 0 0 0 0 5.4351 4.0205 -1.6666 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 4 1 0 0 0 0 1 14 2 0 0 0 0 2 7 1 0 0 0 0 2 27 1 0 0 0 0 3 4 1 0 0 0 0 3 6 2 0 0 0 0 3 11 1 0 0 0 0 4 28 1 0 0 0 0 5 10 3 0 0 0 0 6 13 1 0 0 0 0 6 15 1 0 0 0 0 7 8 2 0 0 0 0 7 16 1 0 0 0 0 8 17 1 0 0 0 0 9 16 2 0 0 0 0 9 12 1 0 0 0 0 10 12 1 0 0 0 0 11 18 2 0 0 0 0 11 29 1 0 0 0 0 12 17 2 0 0 0 0 13 19 1 0 0 0 0 15 22 2 0 0 0 0 15 30 1 0 0 0 0 16 31 1 0 0 0 0 17 32 1 0 0 0 0 18 22 1 0 0 0 0 18 23 1 0 0 0 0 19 21 1 0 0 0 0 19 26 1 0 0 0 0 19 33 1 0 0 0 0 20 21 1 0 0 0 0 20 24 1 0 0 0 0 20 25 1 0 0 0 0 21 34 1 0 0 0 0 21 35 1 0 0 0 0 22 36 1 0 0 0 0 24 37 1 0 0 0 0 24 38 1 0 0 0 0 24 39 1 0 0 0 0 25 40 1 0 0 0 0 25 41 1 0 0 0 0 25 42 1 0 0 0 0 26 43 1 0 0 0 0 26 44 1 0 0 0 0 26 45 1 0 0 0 0 M END > 421871 > Serine/threonine-protein kinase Aurora-A > Homo sapiens > 15857116 > J. Med. Chem.|2005|48|9|3118 > 2d > 2005 > 421871 > Serine/threonine-protein kinase Chk2 > Homo sapiens > 15857116 > J. Med. Chem.|2005|48|9|3118 > 2d > 2005 $$$$