Structure294 Wcorina 06010716263D 1 1.00000 0.00000 CORINA evaluation license 3.40 0067 02.08.2006 54 57 0 0 0 0 0 0 0 0999 V2000 -0.0146 1.3788 -0.0398 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0047 -0.0052 -0.0604 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1989 -0.6954 -0.0809 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4061 -0.0051 -0.0812 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3998 1.4009 -0.0603 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1764 2.0954 -0.0394 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1579 3.5753 -0.0173 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2967 4.2662 -0.0169 N 0 0 0 0 0 0 0 0 0 0 0 0 2.2817 5.5896 0.0023 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1465 6.2731 0.0218 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.0232 5.6526 0.0227 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.0562 4.2705 -0.0024 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4839 6.2781 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 3.4908 7.6727 -0.0959 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4551 8.4127 0.5768 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4617 9.7908 0.4794 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5102 10.4365 -0.2868 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5440 9.7023 -0.9608 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5376 8.3195 -0.8706 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7244 -0.4047 -0.0985 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5417 0.6910 -0.0894 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8021 1.8132 -0.0664 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1820 -1.7961 -0.1225 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2093 -2.2991 -1.5672 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6873 -3.7523 -1.5924 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7135 -4.2353 -2.9795 N 0 0 0 0 0 0 0 0 0 0 0 0 1.6086 10.3389 -1.7135 O 0 0 0 0 0 0 0 0 0 0 0 0 1.6792 11.7652 -1.7663 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5418 12.2870 -0.4756 F 0 0 0 0 0 0 0 0 0 0 0 0 2.9149 12.1516 -2.2964 F 0 0 0 0 0 0 0 0 0 0 0 0 0.5537 12.2990 -2.6547 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.6819 11.9126 -2.1246 F 0 0 0 0 0 0 0 0 0 0 0 0 0.6229 13.6953 -2.7064 F 0 0 0 0 0 0 0 0 0 0 0 0 -0.9584 1.9037 -0.0284 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9269 -0.5515 -0.0600 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1963 -1.7753 -0.0965 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9420 6.2202 0.0390 H 0 0 0 0 0 0 0 0 0 0 0 0 -0.9969 3.7401 -0.0064 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3209 5.7926 0.0712 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1997 7.9105 1.1765 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2119 10.3646 1.0033 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5180 11.5140 -0.3610 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7896 7.7464 -1.3982 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6212 0.6597 -0.0995 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1736 2.8273 -0.0543 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1840 -1.8564 0.3022 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5010 -2.4128 0.4641 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2073 -2.2388 -1.9920 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8903 -1.6825 -2.1538 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6893 -3.8126 -1.1676 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0063 -4.3690 -1.0058 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2878 -3.6410 -3.5584 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0261 -5.1936 -3.0228 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6608 11.8924 -3.6604 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 6 1 0 0 0 0 1 34 1 0 0 0 0 2 3 1 0 0 0 0 2 35 1 0 0 0 0 3 4 2 0 0 0 0 3 36 1 0 0 0 0 4 5 1 0 0 0 0 4 20 1 0 0 0 0 5 6 2 0 0 0 0 5 22 1 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 7 12 1 0 0 0 0 8 9 1 0 0 0 0 9 10 2 0 0 0 0 9 13 1 0 0 0 0 10 11 1 0 0 0 0 11 12 2 0 0 0 0 11 37 1 0 0 0 0 12 38 1 0 0 0 0 13 14 1 0 0 0 0 13 39 1 0 0 0 0 14 15 2 0 0 0 0 14 19 1 0 0 0 0 15 16 1 0 0 0 0 15 40 1 0 0 0 0 16 17 2 0 0 0 0 16 41 1 0 0 0 0 17 18 1 0 0 0 0 17 42 1 0 0 0 0 18 19 2 0 0 0 0 18 27 1 0 0 0 0 19 43 1 0 0 0 0 20 21 1 0 0 0 0 20 23 1 0 0 0 0 21 22 2 0 0 0 0 21 44 1 0 0 0 0 22 45 1 0 0 0 0 23 24 1 0 0 0 0 23 46 1 0 0 0 0 23 47 1 0 0 0 0 24 25 1 0 0 0 0 24 48 1 0 0 0 0 24 49 1 0 0 0 0 25 26 1 0 0 0 0 25 50 1 0 0 0 0 25 51 1 0 0 0 0 26 52 1 0 0 0 0 26 53 1 0 0 0 0 27 28 1 0 0 0 0 28 29 1 0 0 0 0 28 30 1 0 0 0 0 28 31 1 0 0 0 0 31 32 1 0 0 0 0 31 33 1 0 0 0 0 31 54 1 0 0 0 0 M END > (282) 433 > (282) C23H21F4N5O > (282) 459.4454 > (282) PDGFR > (282) 9 > (282) POTENT AND SELECTIVE INHIBITORS OF THE ABL-KINASE: PHENYLAMINOPYRIMIDINE (PAP) DERIVATIVES Bioorganic & Medicinal Chemistry Letters, Vol. 7, No. 2, pp. 187-192, 1997 > (282) 1997 > (282) PDGFR > (282) 1 > (282) TRAIN > (282) 5 $$$$ csChFnd70/05150717532D 40 43 0 0 0 0 0 0 0 0999 V2000 3.9953 7.0077 0.0282 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7568 5.3697 0.0024 N 0 0 0 0 0 0 0 0 0 0 0 0 4.0153 5.4511 0.0092 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4387 7.8187 0.0349 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8495 6.9342 0.0212 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4931 9.4853 0.0546 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3720 9.2690 0.0458 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6559 9.9146 0.0510 O 0 0 0 0 0 0 0 0 0 0 0 0 8.2848 7.6824 0.0267 N 0 0 3 0 0 0 0 0 0 0 0 0 6.9307 10.2219 0.0599 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0275 11.9670 0.0809 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0629 12.8101 -1.3326 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1532 14.4368 -1.3047 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2086 15.2303 0.1202 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1745 14.4015 1.5257 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0768 12.7751 1.5145 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0242 11.7378 3.2797 Cl 0 0 0 0 0 0 0 0 0 0 0 0 6.9942 11.8165 -3.1223 Cl 0 0 0 0 0 0 0 0 0 0 0 0 5.3669 4.6570 -0.0034 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3201 3.0277 -0.0237 N 0 0 3 0 0 0 0 0 0 0 0 0 9.7376 6.7461 0.0123 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8756 2.2423 0.1098 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0966 0.6450 0.3099 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6169 0.8360 -0.6902 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6772 2.8553 1.0528 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2674 2.0345 1.1473 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2566 0.0924 -0.5671 N 0 0 0 0 0 0 0 0 0 0 0 0 2.8914 7.6440 0.0330 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4170 10.1675 0.0648 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1812 15.0907 -2.3980 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2793 16.5023 0.1356 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2185 15.0281 2.6343 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2894 2.4287 -0.1306 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0950 6.5282 -1.2036 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6681 7.3892 0.6240 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5304 5.6243 0.6057 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 0.0000 0.3801 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5391 0.3470 -1.4208 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8433 3.9434 1.6945 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3103 2.4779 1.8622 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 28 1 0 0 0 0 2 19 2 0 0 0 0 2 5 1 0 0 0 0 3 19 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 10 2 0 0 0 0 6 29 1 0 0 0 0 7 9 1 0 0 0 0 7 10 1 0 0 0 0 7 8 2 0 0 0 0 9 21 1 0 0 0 0 10 11 1 0 0 0 0 11 16 1 0 0 0 0 11 12 2 0 0 0 0 12 13 1 0 0 0 0 12 18 1 0 0 0 0 13 14 2 0 0 0 0 13 30 1 0 0 0 0 14 15 1 0 0 0 0 14 31 1 0 0 0 0 15 16 2 0 0 0 0 15 32 1 0 0 0 0 16 17 1 0 0 0 0 19 20 1 0 0 0 0 20 22 1 0 0 0 0 20 33 1 0 0 0 0 21 34 1 0 0 0 0 21 35 1 0 0 0 0 21 36 1 0 0 0 0 22 24 2 0 0 0 0 22 25 1 0 0 0 0 23 27 2 0 0 0 0 23 26 1 0 0 0 0 23 37 1 0 0 0 0 24 27 1 0 0 0 0 24 38 1 0 0 0 0 25 26 2 0 0 0 0 25 39 1 0 0 0 0 26 40 1 0 0 0 0 M END > (104) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 40 > (104) PDGFR-beta > (104) 120 > (104) -1 > (104) P > (104) PDGFR-P102 $$$$ csChFnd70/05150717532D 53 56 0 0 0 0 0 0 0 0999 V2000 7.9488 13.1015 0.0176 C 0 0 0 0 0 0 0 0 0 0 0 0 10.9836 11.3024 -0.0030 N 0 0 0 0 0 0 0 0 0 0 0 0 7.9714 11.3911 0.0014 N 0 0 0 0 0 0 0 0 0 0 0 0 9.5346 13.9931 0.0241 C 0 0 0 0 0 0 0 0 0 0 0 0 11.0850 13.0216 0.0131 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5938 15.8244 0.0407 C 0 0 0 0 0 0 0 0 0 0 0 0 12.7571 15.5874 0.0346 C 0 0 0 0 0 0 0 0 0 0 0 0 14.1678 16.2972 0.0401 O 0 0 0 0 0 0 0 0 0 0 0 0 12.6619 13.8441 0.0183 N 0 0 3 0 0 0 0 0 0 0 0 0 11.1733 16.6341 0.0457 C 0 0 0 0 0 0 0 0 0 0 0 0 11.2792 18.5517 0.0625 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3198 19.4728 -1.4939 C 0 0 0 0 0 0 0 0 0 0 0 0 11.4178 21.2603 -1.4692 C 0 0 0 0 0 0 0 0 0 0 0 0 11.4759 22.1376 0.0936 C 0 0 0 0 0 0 0 0 0 0 0 0 11.4367 21.2323 1.6410 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3312 19.4450 1.6345 C 0 0 0 0 0 0 0 0 0 0 0 0 11.2721 18.3118 3.5780 Cl 0 0 0 0 0 0 0 0 0 0 0 0 11.2478 18.3743 -3.4567 Cl 0 0 0 0 0 0 0 0 0 0 0 0 9.4567 10.5189 -0.0085 C 0 0 0 0 0 0 0 0 0 0 0 0 9.4057 8.7286 -0.0260 N 0 0 3 0 0 0 0 0 0 0 0 0 7.8189 7.8657 0.1207 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5466 6.3209 -0.7635 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5135 8.5473 1.1570 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9477 7.6914 1.2996 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9776 5.4715 -0.6152 C 0 0 0 0 0 0 0 0 0 0 0 0 14.2584 12.8156 0.0067 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6784 6.1573 0.4121 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9682 5.2265 0.5713 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0459 3.9565 2.0928 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3096 3.0116 2.2544 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6948 1.6377 4.6044 O 0 0 0 0 0 0 0 0 0 0 0 0 1.3859 1.7607 3.7530 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 0.7832 4.1420 O 0 0 0 0 0 0 0 0 0 0 0 0 6.7358 13.8004 0.0198 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4112 16.5737 0.0487 H 0 0 0 0 0 0 0 0 0 0 0 0 11.4498 21.9748 -2.6729 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5525 23.5354 0.1058 H 0 0 0 0 0 0 0 0 0 0 0 0 11.4828 21.9249 2.8568 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4711 8.0703 -0.1400 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5605 5.7849 -1.5663 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7232 9.7453 1.8506 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9305 8.2234 2.1011 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7631 4.2734 -1.3069 H 0 0 0 0 0 0 0 0 0 0 0 0 14.6525 12.5727 -1.3283 H 0 0 0 0 0 0 0 0 0 0 0 0 15.2802 13.5243 0.6778 H 0 0 0 0 0 0 0 0 0 0 0 0 14.0305 11.5846 0.6619 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9387 6.1679 0.7956 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7054 4.5165 -0.6218 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0754 3.0151 1.8684 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3085 4.6665 3.2859 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2800 3.9530 2.4787 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0468 2.3016 1.0613 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1107 0.0000 5.1144 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 34 1 0 0 0 0 2 19 2 0 0 0 0 2 5 1 0 0 0 0 3 19 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 10 2 0 0 0 0 6 35 1 0 0 0 0 7 9 1 0 0 0 0 7 10 1 0 0 0 0 7 8 2 0 0 0 0 9 26 1 0 0 0 0 10 11 1 0 0 0 0 11 16 1 0 0 0 0 11 12 2 0 0 0 0 12 13 1 0 0 0 0 12 18 1 0 0 0 0 13 14 2 0 0 0 0 13 36 1 0 0 0 0 14 15 1 0 0 0 0 14 37 1 0 0 0 0 15 16 2 0 0 0 0 15 38 1 0 0 0 0 16 17 1 0 0 0 0 19 20 1 0 0 0 0 20 21 1 0 0 0 0 20 39 1 0 0 0 0 21 22 1 0 0 0 0 21 23 2 0 0 0 0 22 25 2 0 0 0 0 22 40 1 0 0 0 0 23 24 1 0 0 0 0 23 41 1 0 0 0 0 24 27 2 0 0 0 0 24 42 1 0 0 0 0 25 27 1 0 0 0 0 25 43 1 0 0 0 0 26 44 1 0 0 0 0 26 45 1 0 0 0 0 26 46 1 0 0 0 0 27 28 1 0 0 0 0 28 29 1 0 0 0 0 28 47 1 0 0 0 0 28 48 1 0 0 0 0 29 30 1 0 0 0 0 29 49 1 0 0 0 0 29 50 1 0 0 0 0 30 32 1 0 0 0 0 30 51 1 0 0 0 0 30 52 1 0 0 0 0 31 32 2 0 0 0 0 32 33 1 0 0 0 0 33 53 1 0 0 0 0 M END > (107) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 72 > (107) PDGFR-beta > (107) 120 > (107) -1 > (107) P > (107) PDGFR-P105 $$$$ csChFnd70/05150717532D 44 47 0 0 0 0 0 0 0 0999 V2000 6.0744 7.8824 0.0146 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7811 6.2779 -0.0031 N 0 0 0 0 0 0 0 0 0 0 0 0 6.0944 6.3570 0.0006 N 0 0 0 0 0 0 0 0 0 0 0 0 7.4886 8.6776 0.0203 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8713 7.8111 0.0109 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5414 10.3110 0.0347 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3627 10.0996 0.0291 C 0 0 0 0 0 0 0 0 0 0 0 0 11.6208 10.7326 0.0335 O 0 0 0 0 0 0 0 0 0 0 0 0 10.2777 8.5447 0.0155 N 0 0 3 0 0 0 0 0 0 0 0 0 8.9501 11.0331 0.0393 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0444 12.7433 0.0536 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0806 13.5645 -1.3345 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1681 15.1587 -1.3129 C 0 0 0 0 0 0 0 0 0 0 0 0 9.2197 15.9414 0.0807 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1847 15.1344 1.4609 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0906 13.5403 1.4556 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0377 12.5301 3.1891 Cl 0 0 0 0 0 0 0 0 0 0 0 0 9.0167 12.5843 -3.0848 Cl 0 0 0 0 0 0 0 0 0 0 0 0 7.4192 5.5791 -0.0081 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3738 3.9823 -0.0226 N 0 0 3 0 0 0 0 0 0 0 0 0 5.9582 3.2126 0.1088 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7169 1.8335 -0.6807 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7978 3.8213 1.0315 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3873 3.0486 1.1586 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3198 1.0682 -0.5548 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1545 1.6677 0.3554 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7016 7.6275 0.0060 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1421 3.6928 2.1344 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3472 4.8943 2.8320 O 0 0 0 0 0 0 0 0 0 0 0 0 0.7794 2.9478 2.2504 O 0 0 0 0 0 0 0 0 0 0 0 0 4.9925 8.5058 0.0164 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4867 10.9791 0.0416 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1967 15.7956 -2.3866 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2880 17.1882 0.0912 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2257 15.7524 2.5451 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3240 3.3952 -0.1241 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6241 1.3588 -1.3954 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9849 4.8896 1.6502 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1375 0.0000 -1.1752 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0645 1.0662 0.4507 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0534 7.4102 -1.1843 H 0 0 0 0 0 0 0 0 0 0 0 0 12.6126 8.2600 0.6044 H 0 0 0 0 0 0 0 0 0 0 0 0 11.4982 6.5300 0.5910 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 3.4140 2.9025 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 31 1 0 0 0 0 2 19 2 0 0 0 0 2 5 1 0 0 0 0 3 19 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 10 2 0 0 0 0 6 32 1 0 0 0 0 7 9 1 0 0 0 0 7 10 1 0 0 0 0 7 8 2 0 0 0 0 9 27 1 0 0 0 0 10 11 1 0 0 0 0 11 16 1 0 0 0 0 11 12 2 0 0 0 0 12 13 1 0 0 0 0 12 18 1 0 0 0 0 13 14 2 0 0 0 0 13 33 1 0 0 0 0 14 15 1 0 0 0 0 14 34 1 0 0 0 0 15 16 2 0 0 0 0 15 35 1 0 0 0 0 16 17 1 0 0 0 0 19 20 1 0 0 0 0 20 21 1 0 0 0 0 20 36 1 0 0 0 0 21 22 1 0 0 0 0 21 23 2 0 0 0 0 22 25 2 0 0 0 0 22 37 1 0 0 0 0 23 24 1 0 0 0 0 23 38 1 0 0 0 0 24 26 2 0 0 0 0 24 28 1 0 0 0 0 25 26 1 0 0 0 0 25 39 1 0 0 0 0 26 40 1 0 0 0 0 27 41 1 0 0 0 0 27 42 1 0 0 0 0 27 43 1 0 0 0 0 28 30 1 0 0 0 0 28 29 2 0 0 0 0 30 44 1 0 0 0 0 M END > (112) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 70 > (112) PDGFR-beta > (112) 130 > (112) -1 > (112) P > (112) PDGFR-P110 $$$$ csChFnd70/05150717532D 45 48 0 0 0 0 0 0 0 0999 V2000 5.3987 8.3950 0.0166 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2844 6.6844 -0.0028 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4202 6.7687 0.0014 N 0 0 0 0 0 0 0 0 0 0 0 0 6.9066 9.2428 0.0228 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3808 8.3191 0.0123 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9629 10.9841 0.0386 C 0 0 0 0 0 0 0 0 0 0 0 0 9.9708 10.7588 0.0328 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3121 11.4337 0.0381 O 0 0 0 0 0 0 0 0 0 0 0 0 9.8802 9.1012 0.0174 N 0 0 3 0 0 0 0 0 0 0 0 0 8.4648 11.7540 0.0435 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5653 13.5774 0.0593 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6039 14.4532 -1.4205 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6972 16.1529 -1.3972 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7525 16.9871 0.0889 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7151 16.1262 1.5602 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6149 14.4268 1.5542 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5587 13.3493 3.4020 Cl 0 0 0 0 0 0 0 0 0 0 0 0 8.5356 13.4087 -3.2868 Cl 0 0 0 0 0 0 0 0 0 0 0 0 6.8325 5.9394 -0.0081 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7841 4.2370 -0.0241 N 0 0 3 0 0 0 0 0 0 0 0 0 5.2753 3.4166 0.1160 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3983 8.1232 0.0064 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5246 1.1397 -0.5829 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0161 1.9472 -0.7244 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0345 4.0651 1.1011 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2891 1.7922 0.3941 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5452 3.2510 1.2373 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1959 3.9571 2.3008 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3482 3.3265 3.9383 O 0 0 0 0 0 0 0 0 0 0 0 0 4.2454 9.0596 0.0188 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8384 11.6966 0.0462 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7277 16.8322 -2.5416 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8253 18.3162 0.1005 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7590 16.7848 2.7163 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7971 3.6111 -0.1325 H 0 0 0 0 0 0 0 0 0 0 0 0 11.7730 7.8922 -1.2631 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3697 8.7971 0.6445 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1816 6.9527 0.6294 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3206 0.0000 -1.2399 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9802 1.4372 -1.4879 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2338 5.2043 1.7603 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1237 1.1582 0.5026 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2994 5.2965 2.3252 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 3.6095 1.7964 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5179 3.7297 4.6923 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 30 1 0 0 0 0 2 19 2 0 0 0 0 2 5 1 0 0 0 0 3 19 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 10 2 0 0 0 0 6 31 1 0 0 0 0 7 9 1 0 0 0 0 7 10 1 0 0 0 0 7 8 2 0 0 0 0 9 22 1 0 0 0 0 10 11 1 0 0 0 0 11 16 1 0 0 0 0 11 12 2 0 0 0 0 12 13 1 0 0 0 0 12 18 1 0 0 0 0 13 14 2 0 0 0 0 13 32 1 0 0 0 0 14 15 1 0 0 0 0 14 33 1 0 0 0 0 15 16 2 0 0 0 0 15 34 1 0 0 0 0 16 17 1 0 0 0 0 19 20 1 0 0 0 0 20 21 1 0 0 0 0 20 35 1 0 0 0 0 21 24 1 0 0 0 0 21 25 2 0 0 0 0 22 36 1 0 0 0 0 22 37 1 0 0 0 0 22 38 1 0 0 0 0 23 26 1 0 0 0 0 23 24 2 0 0 0 0 23 39 1 0 0 0 0 24 40 1 0 0 0 0 25 27 1 0 0 0 0 25 41 1 0 0 0 0 26 27 2 0 0 0 0 26 42 1 0 0 0 0 27 28 1 0 0 0 0 28 29 1 0 0 0 0 28 43 1 0 0 0 0 28 44 1 0 0 0 0 29 45 1 0 0 0 0 M END > (114) PD166326 > (114) PDGFR-beta > (114) 139 > (114) -1 > (114) P > (114) PDGFR-P112 $$$$ SU11248 analog 12d csChFnd70/05150717532D 56 58 0 0 0 0 0 0 0 0999 V2000 3.8021 3.5390 -3.6327 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8315 1.8431 -4.2818 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1486 1.3280 -5.4298 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4415 2.4960 -5.9375 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0992 4.7250 -4.1367 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4336 4.2082 -5.2981 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0385 7.0501 -4.6887 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4447 6.5893 -3.6997 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5552 5.6210 -5.5898 N 0 0 3 0 0 0 0 0 0 0 0 0 7.7652 8.4774 -4.6906 O 0 0 0 0 0 0 0 0 0 0 0 0 4.4780 7.6630 -2.6008 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1088 9.3537 -2.1647 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9457 11.5381 -1.5523 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2594 12.2131 -1.4650 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0912 10.8242 -1.8513 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8493 9.8244 -1.9693 N 0 0 3 0 0 0 0 0 0 0 0 0 2.1134 10.9263 -1.9104 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6148 12.5557 -1.2293 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7731 14.0416 -1.0453 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6323 15.1204 -2.2169 O 0 0 0 0 0 0 0 0 0 0 0 0 4.4845 14.5179 0.6368 N 0 0 3 0 0 0 0 0 0 0 0 0 4.0012 16.3350 1.0539 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7512 16.5232 3.0410 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2666 18.3454 3.4592 N 0 0 0 0 0 0 0 0 0 0 0 0 1.5310 18.7839 2.7340 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2975 20.7817 2.7149 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3189 18.6557 5.3646 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2320 18.8144 5.9657 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0729 0.2227 -3.6020 Br 0 0 0 0 0 0 0 0 0 0 0 0 2.7728 3.9439 -2.7423 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1640 0.0000 -5.9319 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4615 2.0787 -6.8328 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5793 5.5812 -6.3490 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2394 7.2099 -2.0748 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8463 9.0415 -2.1100 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5810 10.6334 -0.6125 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7148 12.2456 -2.3037 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6140 9.9741 -2.8577 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0789 13.1164 -2.4637 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3581 13.6095 -0.2925 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6146 11.6772 -0.6980 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5970 13.6574 1.5714 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0421 17.2183 0.6178 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7791 16.6699 0.3848 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7103 15.6401 3.4771 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9734 16.1884 3.7100 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4304 18.2784 1.3969 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5101 18.1914 3.5468 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 21.1061 2.2003 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4232 21.2901 4.0489 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3030 21.3722 1.8819 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6199 19.8687 5.6706 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6940 17.5597 6.0445 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2688 19.1711 7.3533 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8976 17.5593 5.7775 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8926 19.8258 5.1949 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 2 0 0 0 0 1 30 1 0 0 0 0 2 3 2 0 0 0 0 2 29 1 0 0 0 0 3 4 1 0 0 0 0 3 31 1 0 0 0 0 4 6 2 0 0 0 0 4 32 1 0 0 0 0 5 8 1 0 0 0 0 5 6 1 0 0 0 0 6 9 1 0 0 0 0 7 9 1 0 0 0 0 7 8 1 0 0 0 0 7 10 2 0 0 0 0 8 11 2 0 0 0 0 9 33 1 0 0 0 0 11 12 1 0 0 0 0 11 34 1 0 0 0 0 12 15 2 0 0 0 0 12 16 1 0 0 0 0 13 16 1 0 0 0 0 13 14 2 0 0 0 0 13 18 1 0 0 0 0 14 15 1 0 0 0 0 14 19 1 0 0 0 0 15 17 1 0 0 0 0 16 35 1 0 0 0 0 17 36 1 0 0 0 0 17 37 1 0 0 0 0 17 38 1 0 0 0 0 18 39 1 0 0 0 0 18 40 1 0 0 0 0 18 41 1 0 0 0 0 19 20 2 0 0 0 0 19 21 1 0 0 0 0 21 22 1 0 0 0 0 21 42 1 0 0 0 0 22 23 1 0 0 0 0 22 43 1 0 0 0 0 22 44 1 0 0 0 0 23 24 1 0 0 0 0 23 45 1 0 0 0 0 23 46 1 0 0 0 0 24 25 1 0 0 0 0 24 27 1 0 0 0 0 25 26 1 0 0 0 0 25 47 1 0 0 0 0 25 48 1 0 0 0 0 26 49 1 0 0 0 0 26 50 1 0 0 0 0 26 51 1 0 0 0 0 27 28 1 0 0 0 0 27 52 1 0 0 0 0 27 53 1 0 0 0 0 28 54 1 0 0 0 0 28 55 1 0 0 0 0 28 56 1 0 0 0 0 M END > (13) SU11248 analog 12d > (13) PDGFR-beta > (13) 5 > (13) -1 > (13) P > (13) PDGFR-P11 $$$$ Structure144 csChFnd70/05150717532D 65 67 0 0 0 0 0 0 0 0999 V2000 12.8264 11.0367 -0.5482 N 0 0 0 0 0 0 0 0 0 0 0 0 12.6159 9.3208 -0.5021 C 0 0 0 0 0 0 0 0 0 0 0 0 13.9319 8.2242 -0.5631 N 0 0 0 0 0 0 0 0 0 0 0 0 15.5640 8.8149 -0.6768 C 0 0 0 0 0 0 0 0 0 0 0 0 15.8353 10.6386 -0.7294 C 0 0 0 0 0 0 0 0 0 0 0 0 16.9152 7.7316 -0.7398 N 0 0 0 0 0 0 0 0 0 0 0 0 18.5221 8.3110 -0.8512 C 0 0 0 0 0 0 0 0 0 0 0 0 18.8902 10.1056 -0.9093 C 0 0 0 0 0 0 0 0 0 0 0 0 19.8823 7.1300 -0.9110 N 0 0 3 0 0 0 0 0 0 0 0 0 19.5526 5.4113 -0.8569 C 0 0 0 0 0 0 0 0 0 0 0 0 20.8740 4.2643 -0.9149 N 0 0 3 0 0 0 0 0 0 0 0 0 18.0632 4.8959 -0.7554 O 0 0 0 0 0 0 0 0 0 0 0 0 10.9503 8.6609 -0.3849 N 0 0 3 0 0 0 0 0 0 0 0 0 20.7115 10.7195 -1.0335 C 0 0 0 0 0 0 0 0 0 0 0 0 21.6680 11.0405 0.4716 C 0 0 0 0 0 0 0 0 0 0 0 0 23.3646 11.6118 0.3471 C 0 0 0 0 0 0 0 0 0 0 0 0 24.1149 11.8663 -1.2656 C 0 0 0 0 0 0 0 0 0 0 0 0 23.1731 11.5504 -2.7630 C 0 0 0 0 0 0 0 0 0 0 0 0 21.4780 10.9715 -2.6560 C 0 0 0 0 0 0 0 0 0 0 0 0 14.3821 11.7419 -0.6594 C 0 0 0 0 0 0 0 0 0 0 0 0 17.5350 11.2897 -0.8499 C 0 0 0 0 0 0 0 0 0 0 0 0 20.2985 10.5751 -4.5368 Cl 0 0 0 0 0 0 0 0 0 0 0 0 20.7283 10.7233 2.4970 Cl 0 0 0 0 0 0 0 0 0 0 0 0 22.2276 1.3899 -0.9408 C 0 0 0 0 0 0 0 0 0 0 0 0 20.5156 2.3960 -0.8560 C 0 0 0 0 0 0 0 0 0 0 0 0 9.4610 9.8434 -0.3146 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7818 8.7874 -0.1889 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2262 10.0224 -0.1156 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5472 8.9664 0.0103 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0536 10.1523 0.0807 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1594 8.6839 -2.0114 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4124 9.1970 -0.1079 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8329 12.7215 1.5054 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0682 11.1756 1.6914 C 0 0 0 0 0 0 0 0 0 0 0 0 21.0707 7.5413 -0.9920 H 0 0 0 0 0 0 0 0 0 0 0 0 22.0623 4.6755 -0.9959 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7676 7.4145 -0.3491 H 0 0 0 0 0 0 0 0 0 0 0 0 24.1067 11.8607 1.5115 H 0 0 0 0 0 0 0 0 0 0 0 0 25.4413 12.3140 -1.3561 H 0 0 0 0 0 0 0 0 0 0 0 0 23.7662 11.7520 -4.0185 H 0 0 0 0 0 0 0 0 0 0 0 0 14.5372 13.1358 -0.6959 H 0 0 0 0 0 0 0 0 0 0 0 0 17.7791 12.6706 -0.8922 H 0 0 0 0 0 0 0 0 0 0 0 0 22.9002 1.7036 -2.1467 H 0 0 0 0 0 0 0 0 0 0 0 0 23.0414 1.7494 0.1608 H 0 0 0 0 0 0 0 0 0 0 0 0 21.9610 0.0000 -0.8970 H 0 0 0 0 0 0 0 0 0 0 0 0 19.8430 2.0823 0.3500 H 0 0 0 0 0 0 0 0 0 0 0 0 19.7017 2.0366 -1.9576 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5772 10.6821 0.8202 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4326 10.6370 -1.4871 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6655 7.9487 -1.3238 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8101 7.9938 0.9835 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3425 10.8611 1.0194 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1981 10.8160 -1.2879 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4309 8.1277 -1.1247 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5754 8.1729 1.1827 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0098 9.8509 -2.7990 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2882 7.9548 -2.4577 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 7.8801 -2.1335 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4502 8.0308 0.6943 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3370 10.0200 0.3061 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5034 12.2509 1.3786 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9341 13.5471 2.6513 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1811 13.4681 0.3536 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6470 10.3621 2.7712 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3802 11.6469 1.9393 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 20 2 0 0 0 0 2 3 2 0 0 0 0 2 13 1 0 0 0 0 3 4 1 0 0 0 0 4 6 2 0 0 0 0 4 5 1 0 0 0 0 5 20 1 0 0 0 0 5 21 2 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 7 9 1 0 0 0 0 8 14 1 0 0 0 0 8 21 1 0 0 0 0 9 10 1 0 0 0 0 9 35 1 0 0 0 0 10 11 1 0 0 0 0 10 12 2 0 0 0 0 11 25 1 0 0 0 0 11 36 1 0 0 0 0 13 26 1 0 0 0 0 13 37 1 0 0 0 0 14 15 2 0 0 0 0 14 19 1 0 0 0 0 15 16 1 0 0 0 0 15 23 1 0 0 0 0 16 17 2 0 0 0 0 16 38 1 0 0 0 0 17 18 1 0 0 0 0 17 39 1 0 0 0 0 18 19 2 0 0 0 0 18 40 1 0 0 0 0 19 22 1 0 0 0 0 20 41 1 0 0 0 0 21 42 1 0 0 0 0 24 25 1 0 0 0 0 24 43 1 0 0 0 0 24 44 1 0 0 0 0 24 45 1 0 0 0 0 25 46 1 0 0 0 0 25 47 1 0 0 0 0 26 27 1 0 0 0 0 26 48 1 0 0 0 0 26 49 1 0 0 0 0 27 28 1 0 0 0 0 27 50 1 0 0 0 0 27 51 1 0 0 0 0 28 29 1 0 0 0 0 28 52 1 0 0 0 0 28 53 1 0 0 0 0 29 30 1 0 0 0 0 29 54 1 0 0 0 0 29 55 1 0 0 0 0 30 32 1 0 0 0 0 30 34 1 0 0 0 0 31 32 1 0 0 0 0 31 56 1 0 0 0 0 31 57 1 0 0 0 0 31 58 1 0 0 0 0 32 59 1 0 0 0 0 32 60 1 0 0 0 0 33 34 1 0 0 0 0 33 61 1 0 0 0 0 33 62 1 0 0 0 0 33 63 1 0 0 0 0 34 64 1 0 0 0 0 34 65 1 0 0 0 0 M END > (138) 9240345-6d > (138) PDGFR-beta > (138) 190 > (138) -1 > (138) P > (138) PDGFR-P136 $$$$ 1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3f csChFnd70/05150717532D 39 41 0 0 0 0 0 0 0 0999 V2000 3.9757 9.6493 0.4550 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3138 7.7713 0.0966 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9930 8.2357 0.4313 N 0 0 0 0 0 0 0 0 0 0 0 0 2.8033 10.5044 0.7638 N 0 0 0 0 0 0 0 0 0 0 0 0 5.3245 10.1188 0.1262 N 0 0 3 0 0 0 0 0 0 0 0 0 6.1601 8.8815 -0.0985 N 0 0 0 0 0 0 0 0 0 0 0 0 5.7674 11.4955 0.0343 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9238 12.4703 0.2566 O 0 0 0 0 0 0 0 0 0 0 0 0 5.7241 6.3353 -0.0243 N 0 0 3 0 0 0 0 0 0 0 0 0 4.6946 5.2473 0.0933 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2861 5.5002 -0.3347 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2714 4.4224 -0.2174 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6561 3.0928 0.3255 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0572 2.8375 0.7529 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0786 3.9085 0.6329 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3789 0.8086 -1.0557 N 0 0 0 0 0 0 0 0 0 0 0 0 1.8622 0.7644 1.5529 O 0 0 0 0 0 0 0 0 0 0 0 0 1.3582 1.7207 0.4732 S 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 2.4172 0.5417 O 0 0 0 0 0 0 0 0 0 0 0 0 7.2632 11.8179 -0.3329 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8552 11.8489 -0.9725 C 0 0 0 0 0 0 0 0 0 0 0 0 9.2735 13.1560 -0.8139 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8397 13.1653 -0.4583 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6094 10.5356 -0.6755 S 0 0 0 0 0 0 0 0 0 0 0 0 6.9873 14.5241 -0.2293 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8840 10.0669 0.9903 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8984 11.5429 0.7543 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7243 6.0909 -0.1902 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9848 6.5385 -0.7583 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1762 4.6184 -0.5495 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3538 1.7980 1.1771 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1737 3.7069 0.9621 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0362 1.0828 -1.8177 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7339 0.0000 -1.1895 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9654 11.6521 -1.2500 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8864 14.1319 -0.9565 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0477 14.8377 0.8982 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4294 15.3798 -0.8970 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8683 14.3375 -0.5235 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 5 1 0 0 0 0 1 4 1 0 0 0 0 2 3 1 0 0 0 0 2 6 2 0 0 0 0 2 9 1 0 0 0 0 4 26 1 0 0 0 0 4 27 1 0 0 0 0 5 6 1 0 0 0 0 5 7 1 0 0 0 0 7 8 2 0 0 0 0 7 20 1 0 0 0 0 9 10 1 0 0 0 0 9 28 1 0 0 0 0 10 15 1 0 0 0 0 10 11 2 0 0 0 0 11 12 1 0 0 0 0 11 29 1 0 0 0 0 12 13 2 0 0 0 0 12 30 1 0 0 0 0 13 14 1 0 0 0 0 13 18 1 0 0 0 0 14 15 2 0 0 0 0 14 31 1 0 0 0 0 15 32 1 0 0 0 0 16 18 1 0 0 0 0 16 33 1 0 0 0 0 16 34 1 0 0 0 0 17 18 2 0 0 0 0 18 19 2 0 0 0 0 20 23 2 0 0 0 0 20 24 1 0 0 0 0 21 22 2 0 0 0 0 21 24 1 0 0 0 0 21 35 1 0 0 0 0 22 23 1 0 0 0 0 22 36 1 0 0 0 0 23 25 1 0 0 0 0 25 37 1 0 0 0 0 25 38 1 0 0 0 0 25 39 1 0 0 0 0 M END > (187) 1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3f > (187) PDGFR-beta > (187) 310 > (187) -1 > (187) P > (187) PDGFR-P185 $$$$ Structure143 csChFnd70/05150717532D 71 73 0 0 0 0 0 0 0 0999 V2000 12.1645 8.2037 -2.0747 N 0 0 0 0 0 0 0 0 0 0 0 0 12.4471 6.5008 -2.1682 C 0 0 0 0 0 0 0 0 0 0 0 0 13.9768 5.8364 -2.5597 N 0 0 0 0 0 0 0 0 0 0 0 0 15.3303 6.8781 -2.8847 C 0 0 0 0 0 0 0 0 0 0 0 0 15.0741 8.7016 -2.7969 C 0 0 0 0 0 0 0 0 0 0 0 0 16.8893 6.2367 -3.2827 N 0 0 0 0 0 0 0 0 0 0 0 0 18.2224 7.2601 -3.6023 C 0 0 0 0 0 0 0 0 0 0 0 0 18.0645 9.0841 -3.5390 C 0 0 0 0 0 0 0 0 0 0 0 0 19.8174 6.5278 -4.0086 N 0 0 3 0 0 0 0 0 0 0 0 0 19.9900 4.7877 -4.0743 C 0 0 0 0 0 0 0 0 0 0 0 0 21.5392 4.0763 -4.4690 N 0 0 3 0 0 0 0 0 0 0 0 0 18.7479 3.8597 -3.7777 O 0 0 0 0 0 0 0 0 0 0 0 0 11.0820 5.3831 -1.8411 N 0 0 3 0 0 0 0 0 0 0 0 0 19.5877 10.2034 -3.9037 C 0 0 0 0 0 0 0 0 0 0 0 0 20.6858 10.7121 -2.5562 C 0 0 0 0 0 0 0 0 0 0 0 0 22.1031 11.7545 -2.9046 C 0 0 0 0 0 0 0 0 0 0 0 0 22.4342 12.2942 -4.5851 C 0 0 0 0 0 0 0 0 0 0 0 0 21.3505 11.7942 -5.9270 C 0 0 0 0 0 0 0 0 0 0 0 0 19.9331 10.7458 -5.5968 C 0 0 0 0 0 0 0 0 0 0 0 0 13.4150 9.3325 -2.3730 C 0 0 0 0 0 0 0 0 0 0 0 0 16.4734 9.8210 -3.1337 C 0 0 0 0 0 0 0 0 0 0 0 0 18.5747 10.1191 -7.2828 Cl 0 0 0 0 0 0 0 0 0 0 0 0 20.2715 10.0373 -0.4457 Cl 0 0 0 0 0 0 0 0 0 0 0 0 21.7267 2.1847 -4.5406 C 0 0 0 0 0 0 0 0 0 0 0 0 20.4965 1.4488 -5.9159 C 0 0 0 0 0 0 0 0 0 0 0 0 23.6002 1.7223 -5.0126 C 0 0 0 0 0 0 0 0 0 0 0 0 21.2793 1.4073 -2.7680 C 0 0 0 0 0 0 0 0 0 0 0 0 9.3668 6.0792 -1.4029 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0994 4.5786 -1.1053 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3082 5.3056 -0.6477 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0408 3.8052 -0.3501 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3210 4.5030 0.0893 N 0 0 0 0 0 0 0 0 0 0 0 0 1.0647 6.5791 -0.7533 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5684 5.4465 -1.3877 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6138 2.6153 2.5483 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1521 3.1175 0.6826 C 0 0 0 0 0 0 0 0 0 0 0 0 20.8084 7.2683 -4.2452 H 0 0 0 0 0 0 0 0 0 0 0 0 22.5302 4.8166 -4.7057 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2594 4.1377 -1.9018 H 0 0 0 0 0 0 0 0 0 0 0 0 22.9543 12.1493 -1.8623 H 0 0 0 0 0 0 0 0 0 0 0 0 23.5436 13.1099 -4.8508 H 0 0 0 0 0 0 0 0 0 0 0 0 21.6156 12.2202 -7.2364 H 0 0 0 0 0 0 0 0 0 0 0 0 13.1708 10.7110 -2.2934 H 0 0 0 0 0 0 0 0 0 0 0 0 16.3154 11.2132 -3.0761 H 0 0 0 0 0 0 0 0 0 0 0 0 20.8152 2.0026 -7.1787 H 0 0 0 0 0 0 0 0 0 0 0 0 20.6361 0.0414 -5.9691 H 0 0 0 0 0 0 0 0 0 0 0 0 19.1618 1.7782 -5.5797 H 0 0 0 0 0 0 0 0 0 0 0 0 24.4766 2.2465 -4.0328 H 0 0 0 0 0 0 0 0 0 0 0 0 23.7398 0.3149 -5.0658 H 0 0 0 0 0 0 0 0 0 0 0 0 23.9190 2.2760 -6.2754 H 0 0 0 0 0 0 0 0 0 0 0 0 19.9447 1.7368 -2.4317 H 0 0 0 0 0 0 0 0 0 0 0 0 21.4189 0.0000 -2.8212 H 0 0 0 0 0 0 0 0 0 0 0 0 22.1557 1.9316 -1.7882 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4607 6.8581 -0.2250 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8998 6.8873 -2.4669 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0055 3.7998 -2.2833 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5665 3.7706 -0.0414 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4021 6.0845 0.5303 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8411 6.1137 -1.7116 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9470 3.0262 -1.5280 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5079 2.9970 0.7139 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6201 7.4084 -1.8104 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 5.7519 -0.3229 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5027 7.3837 0.3254 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5596 6.2660 -1.9785 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0902 4.5202 -2.3449 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4628 3.7421 3.3913 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7529 1.5804 2.9852 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9548 2.1655 2.5976 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8141 3.5764 0.6349 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2938 1.9883 -0.1588 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 20 2 0 0 0 0 2 3 2 0 0 0 0 2 13 1 0 0 0 0 3 4 1 0 0 0 0 4 6 2 0 0 0 0 4 5 1 0 0 0 0 5 20 1 0 0 0 0 5 21 2 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 7 9 1 0 0 0 0 8 14 1 0 0 0 0 8 21 1 0 0 0 0 9 10 1 0 0 0 0 9 37 1 0 0 0 0 10 11 1 0 0 0 0 10 12 2 0 0 0 0 11 24 1 0 0 0 0 11 38 1 0 0 0 0 13 28 1 0 0 0 0 13 39 1 0 0 0 0 14 15 2 0 0 0 0 14 19 1 0 0 0 0 15 16 1 0 0 0 0 15 23 1 0 0 0 0 16 17 2 0 0 0 0 16 40 1 0 0 0 0 17 18 1 0 0 0 0 17 41 1 0 0 0 0 18 19 2 0 0 0 0 18 42 1 0 0 0 0 19 22 1 0 0 0 0 20 43 1 0 0 0 0 21 44 1 0 0 0 0 24 25 1 0 0 0 0 24 26 1 0 0 0 0 24 27 1 0 0 0 0 25 45 1 0 0 0 0 25 46 1 0 0 0 0 25 47 1 0 0 0 0 26 48 1 0 0 0 0 26 49 1 0 0 0 0 26 50 1 0 0 0 0 27 51 1 0 0 0 0 27 52 1 0 0 0 0 27 53 1 0 0 0 0 28 29 1 0 0 0 0 28 54 1 0 0 0 0 28 55 1 0 0 0 0 29 30 1 0 0 0 0 29 56 1 0 0 0 0 29 57 1 0 0 0 0 30 31 1 0 0 0 0 30 58 1 0 0 0 0 30 59 1 0 0 0 0 31 32 1 0 0 0 0 31 60 1 0 0 0 0 31 61 1 0 0 0 0 32 34 1 0 0 0 0 32 36 1 0 0 0 0 33 34 1 0 0 0 0 33 62 1 0 0 0 0 33 63 1 0 0 0 0 33 64 1 0 0 0 0 34 65 1 0 0 0 0 34 66 1 0 0 0 0 35 36 1 0 0 0 0 35 67 1 0 0 0 0 35 68 1 0 0 0 0 35 69 1 0 0 0 0 36 70 1 0 0 0 0 36 71 1 0 0 0 0 M END > (188) 9240345-6c > (188) PDGFR-beta > (188) 310 > (188) -1 > (188) P > (188) PDGFR-P186 $$$$ Structure55 csChFnd70/05150717532D 41 44 0 0 0 0 0 0 0 0999 V2000 3.9982 10.0469 -0.5999 N 0 0 0 0 0 0 0 0 0 0 0 0 5.1745 10.7774 -0.1926 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4439 10.1361 0.0250 N 0 0 0 0 0 0 0 0 0 0 0 0 6.5871 8.7120 -0.1600 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3607 7.8986 -0.5927 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0404 8.6289 -0.8092 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8979 8.0384 0.0635 N 0 0 3 0 0 0 0 0 0 0 0 0 8.0369 6.5939 -0.1259 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7862 5.7182 -0.5742 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4739 6.3810 -0.8003 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9399 4.1293 -0.7816 C 0 0 0 0 0 0 0 0 0 0 0 0 9.2085 6.0130 0.0771 O 0 0 0 0 0 0 0 0 0 0 0 0 9.1595 8.8989 0.5121 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3272 3.5725 -2.1376 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4692 2.0902 -2.3236 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2280 1.1582 -1.1695 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8434 1.7031 0.1773 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7043 3.1835 0.3796 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2215 3.8652 2.0707 Cl 0 0 0 0 0 0 0 0 0 0 0 0 7.6292 4.7403 -3.5877 Cl 0 0 0 0 0 0 0 0 0 0 0 0 5.0698 12.2611 0.0109 N 0 0 3 0 0 0 0 0 0 0 0 0 3.7185 12.9478 -0.0877 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4701 12.2284 0.3616 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1370 12.9098 0.2627 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0439 14.3067 -0.2828 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2846 15.0257 -0.7315 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6219 14.3531 -0.6293 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0790 8.0432 -1.1399 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5389 5.7537 -1.1308 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2046 8.9466 1.6945 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1483 8.3947 0.0993 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0642 9.9959 0.0762 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7688 1.6579 -3.3725 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3401 0.0000 -1.3207 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6561 0.9696 1.0739 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9339 12.8263 0.2221 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5421 11.1374 0.7873 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1659 12.3510 0.6114 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 14.8371 -0.3590 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2082 16.1164 -1.1574 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5904 14.9152 -0.9799 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 2 3 1 0 0 0 0 2 21 1 0 0 0 0 3 4 2 0 0 0 0 4 7 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 5 6 2 0 0 0 0 6 28 1 0 0 0 0 7 8 1 0 0 0 0 7 13 1 0 0 0 0 8 9 1 0 0 0 0 8 12 2 0 0 0 0 9 11 1 0 0 0 0 9 10 2 0 0 0 0 10 29 1 0 0 0 0 11 14 2 0 0 0 0 11 18 1 0 0 0 0 13 30 1 0 0 0 0 13 31 1 0 0 0 0 13 32 1 0 0 0 0 14 15 1 0 0 0 0 14 20 1 0 0 0 0 15 16 2 0 0 0 0 15 33 1 0 0 0 0 16 17 1 0 0 0 0 16 34 1 0 0 0 0 17 18 2 0 0 0 0 17 35 1 0 0 0 0 18 19 1 0 0 0 0 21 22 1 0 0 0 0 21 36 1 0 0 0 0 22 23 2 0 0 0 0 22 27 1 0 0 0 0 23 24 1 0 0 0 0 23 37 1 0 0 0 0 24 25 2 0 0 0 0 24 38 1 0 0 0 0 25 26 1 0 0 0 0 25 39 1 0 0 0 0 26 27 2 0 0 0 0 26 40 1 0 0 0 0 27 41 1 0 0 0 0 M END > (195) 9599227-5 > (195) PDGFR-beta > (195) 330 > (195) -1 > (195) P > (195) PDGFR-P193 $$$$ 6-arylpyrido[2,3-d]pyrimidine deriv. 15 csChFnd70/05150717532D 51 53 0 0 0 0 0 0 0 0999 V2000 1.2089 5.0278 0.0120 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7123 2.4487 -0.0163 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7930 5.9155 0.0017 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3476 4.9408 -0.0185 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8763 7.7288 0.0111 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9849 7.4431 -0.0195 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4950 8.4948 0.0004 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2320 3.3247 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 4.2363 3.2143 -0.0266 N 0 0 0 0 0 0 0 0 0 0 0 0 5.8735 5.7441 -0.0282 N 0 0 0 0 0 0 0 0 0 0 0 0 4.6603 10.4040 0.0090 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9065 13.0734 1.5714 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7527 11.2965 1.5713 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7315 11.3125 -1.5449 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8853 13.0893 -1.5290 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9696 13.9687 0.0253 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6508 0.6638 -0.0252 N 0 0 0 0 0 0 0 0 0 0 0 0 4.6412 10.3561 -3.2392 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6841 10.3229 3.2567 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6028 8.2154 -0.0309 N 0 0 3 0 0 0 0 0 0 0 0 0 9.0385 7.2292 -0.0505 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9155 5.6628 -0.0583 O 0 0 0 0 0 0 0 0 0 0 0 0 10.6103 7.9794 -0.0615 N 0 0 3 0 0 0 0 0 0 0 0 0 12.1709 6.9075 -0.0828 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1706 5.7753 -1.7039 C 0 0 0 0 0 0 0 0 0 0 0 0 13.7697 8.0711 -0.0917 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2022 5.7568 1.5249 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 5.7251 0.0329 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7146 8.5023 0.0260 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9777 13.7662 2.7810 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9407 13.7945 -2.7322 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0895 15.3593 0.0317 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5443 0.0747 -0.0178 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7142 0.0000 -0.0389 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2962 10.2397 -3.6415 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3644 11.0656 -4.2181 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1977 9.0715 -3.0835 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9907 9.9732 3.6505 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0976 11.1369 4.2456 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9145 9.1545 3.0931 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7009 9.4652 -0.0247 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7084 9.2293 -0.0553 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1484 6.5950 -2.8492 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3317 4.9777 -1.7198 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0316 4.9463 -1.6975 H 0 0 0 0 0 0 0 0 0 0 0 0 13.7698 8.8776 1.0631 H 0 0 0 0 0 0 0 0 0 0 0 0 14.9308 7.2734 -0.1075 H 0 0 0 0 0 0 0 0 0 0 0 0 13.7475 8.8908 -1.2371 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0631 4.9278 1.5312 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3631 4.9593 1.5090 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2023 6.5635 2.6798 H 0 0 0 0 0 0 0 0 0 0 0 0 1 8 1 0 0 0 0 1 3 2 0 0 0 0 1 28 1 0 0 0 0 2 8 2 0 0 0 0 2 9 1 0 0 0 0 2 17 1 0 0 0 0 3 5 1 0 0 0 0 3 4 1 0 0 0 0 4 9 2 0 0 0 0 4 10 1 0 0 0 0 5 7 2 0 0 0 0 5 29 1 0 0 0 0 6 10 2 0 0 0 0 6 7 1 0 0 0 0 6 20 1 0 0 0 0 7 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 30 1 0 0 0 0 13 19 1 0 0 0 0 14 15 1 0 0 0 0 14 18 1 0 0 0 0 15 16 2 0 0 0 0 15 31 1 0 0 0 0 16 32 1 0 0 0 0 17 33 1 0 0 0 0 17 34 1 0 0 0 0 18 35 1 0 0 0 0 18 36 1 0 0 0 0 18 37 1 0 0 0 0 19 38 1 0 0 0 0 19 39 1 0 0 0 0 19 40 1 0 0 0 0 20 21 1 0 0 0 0 20 41 1 0 0 0 0 21 23 1 0 0 0 0 21 22 2 0 0 0 0 23 24 1 0 0 0 0 23 42 1 0 0 0 0 24 25 1 0 0 0 0 24 26 1 0 0 0 0 24 27 1 0 0 0 0 25 43 1 0 0 0 0 25 44 1 0 0 0 0 25 45 1 0 0 0 0 26 46 1 0 0 0 0 26 47 1 0 0 0 0 26 48 1 0 0 0 0 27 49 1 0 0 0 0 27 50 1 0 0 0 0 27 51 1 0 0 0 0 M END > (197) PD089828 analog 15 > (197) PDGFR-beta > (197) 340 > (197) -1 > (197) P > (197) PDGFR-P195 $$$$ Pyrazine-Pyridine Biheteroaryl 7 csChFnd70/05150717532D 43 45 0 0 0 0 0 0 0 0999 V2000 1.0071 10.7751 -0.0812 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2612 8.6909 -0.3371 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5369 9.4575 -0.3670 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2781 11.5496 -0.1101 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0321 9.3696 -0.1951 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5148 10.8738 -0.2523 N 0 0 0 0 0 0 0 0 0 0 0 0 4.9175 8.6954 -0.5259 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1996 9.4525 -0.5569 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5027 7.3794 -0.8139 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2747 6.5453 -0.7868 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9526 7.2083 -0.6402 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4283 8.7813 -0.6978 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5273 13.7958 0.1142 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6390 15.1430 -0.4973 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6865 13.2130 0.8354 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9477 13.9715 0.9372 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0585 15.3105 0.3226 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9045 15.8970 -0.3918 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0462 17.5813 -1.1555 Cl 0 0 0 0 0 0 0 0 0 0 0 0 2.2495 13.0304 0.0095 N 0 0 3 0 0 0 0 0 0 0 0 0 6.3661 5.0604 -0.9112 N 0 0 3 0 0 0 0 0 0 0 0 0 7.7632 4.3732 -1.0718 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5645 2.7546 -1.1848 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0235 2.0369 -1.3525 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8379 0.5252 -1.4581 O 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 11.3254 0.0394 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2774 7.5410 -0.4303 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1852 10.6026 -0.4650 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5326 6.8718 -0.9276 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9792 6.5893 -0.6151 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7385 15.6009 -1.0548 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6009 12.1676 1.3164 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8488 13.5185 1.4978 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0460 15.9016 0.4045 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3426 13.5319 0.0204 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5047 4.4847 -0.8915 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2819 4.7690 -2.0363 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4255 4.6193 -0.1460 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0457 2.3589 -0.2202 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9022 2.5086 -2.1106 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5422 2.4326 -2.3171 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6858 2.2829 -0.4267 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7210 0.0000 -1.5668 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 1 0 0 0 0 1 4 2 0 0 0 0 1 26 1 0 0 0 0 2 5 2 0 0 0 0 2 3 1 0 0 0 0 2 27 1 0 0 0 0 3 6 2 0 0 0 0 3 7 1 0 0 0 0 4 6 1 0 0 0 0 4 20 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 12 2 0 0 0 0 8 28 1 0 0 0 0 9 12 1 0 0 0 0 9 10 2 0 0 0 0 9 29 1 0 0 0 0 10 11 1 0 0 0 0 10 21 1 0 0 0 0 11 30 1 0 0 0 0 13 20 1 0 0 0 0 13 14 2 0 0 0 0 13 15 1 0 0 0 0 14 18 1 0 0 0 0 14 31 1 0 0 0 0 15 16 2 0 0 0 0 15 32 1 0 0 0 0 16 17 1 0 0 0 0 16 33 1 0 0 0 0 17 18 2 0 0 0 0 17 34 1 0 0 0 0 18 19 1 0 0 0 0 20 35 1 0 0 0 0 21 22 1 0 0 0 0 21 36 1 0 0 0 0 22 23 1 0 0 0 0 22 37 1 0 0 0 0 22 38 1 0 0 0 0 23 24 1 0 0 0 0 23 39 1 0 0 0 0 23 40 1 0 0 0 0 24 25 1 0 0 0 0 24 41 1 0 0 0 0 24 42 1 0 0 0 0 25 43 1 0 0 0 0 M END > (203) Pyrazine-Pyridine Biheteroaryl 7 > (203) PDGFR-beta > (203) 360 > (203) -1 > (203) P > (203) PDGFR-P201 $$$$ csChFnd70/05150717532D 44 47 0 0 0 0 0 0 0 0999 V2000 5.5168 9.3778 0.0279 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2645 7.7482 0.0023 N 0 0 0 0 0 0 0 0 0 0 0 0 5.5366 7.8291 0.0090 N 0 0 0 0 0 0 0 0 0 0 0 0 6.9528 10.1847 0.0346 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3565 9.3048 0.0210 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0070 11.8429 0.0542 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8712 11.6278 0.0455 C 0 0 0 0 0 0 0 0 0 0 0 0 11.1486 12.2701 0.0510 O 0 0 0 0 0 0 0 0 0 0 0 0 9.7847 10.0492 0.0265 N 0 0 3 0 0 0 0 0 0 0 0 0 8.4372 12.5757 0.0595 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5335 14.3121 0.0804 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5686 15.1509 -1.3260 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6578 16.7694 -1.2984 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7123 17.5589 0.1195 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6785 16.7345 1.5178 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5826 15.1160 1.5066 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5310 14.0840 3.2630 Cl 0 0 0 0 0 0 0 0 0 0 0 0 8.5011 14.1623 -3.1066 Cl 0 0 0 0 0 0 0 0 0 0 0 0 6.8816 7.0390 -0.0034 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8351 5.4184 -0.0236 N 0 0 3 0 0 0 0 0 0 0 0 0 11.2301 9.1177 0.0122 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3956 4.6356 0.1095 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1401 3.2385 -0.6860 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2034 5.2472 1.0487 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8015 4.4338 1.1455 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7868 2.4949 -0.5652 N 0 0 0 0 0 0 0 0 0 0 0 0 2.6290 3.0445 0.3096 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2574 2.2380 0.3977 O 0 0 0 0 0 0 0 0 0 0 0 0 1.1536 0.8139 -0.4826 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4185 10.0110 0.0327 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9362 12.5216 0.0643 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6855 17.4200 -2.3860 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7820 18.8247 0.1346 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7218 17.3579 2.6208 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7994 4.8225 -0.1298 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5858 8.9010 -1.1976 H 0 0 0 0 0 0 0 0 0 0 0 0 12.1559 9.7577 0.6207 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0240 8.0015 0.6026 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0590 2.7540 -1.4128 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3706 6.3303 1.6861 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8511 4.8760 1.8584 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 0.2885 -0.3091 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3244 1.0671 -1.7250 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0572 0.0000 -0.0850 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 30 1 0 0 0 0 2 19 2 0 0 0 0 2 5 1 0 0 0 0 3 19 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 10 2 0 0 0 0 6 31 1 0 0 0 0 7 9 1 0 0 0 0 7 10 1 0 0 0 0 7 8 2 0 0 0 0 9 21 1 0 0 0 0 10 11 1 0 0 0 0 11 16 1 0 0 0 0 11 12 2 0 0 0 0 12 13 1 0 0 0 0 12 18 1 0 0 0 0 13 14 2 0 0 0 0 13 32 1 0 0 0 0 14 15 1 0 0 0 0 14 33 1 0 0 0 0 15 16 2 0 0 0 0 15 34 1 0 0 0 0 16 17 1 0 0 0 0 19 20 1 0 0 0 0 20 22 1 0 0 0 0 20 35 1 0 0 0 0 21 36 1 0 0 0 0 21 37 1 0 0 0 0 21 38 1 0 0 0 0 22 23 2 0 0 0 0 22 24 1 0 0 0 0 23 26 1 0 0 0 0 23 39 1 0 0 0 0 24 25 2 0 0 0 0 24 40 1 0 0 0 0 25 27 1 0 0 0 0 25 41 1 0 0 0 0 26 27 2 0 0 0 0 27 28 1 0 0 0 0 28 29 1 0 0 0 0 29 42 1 0 0 0 0 29 43 1 0 0 0 0 29 44 1 0 0 0 0 M END > (213) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 41 > (213) PDGFR-beta > (213) 400 > (213) -1 > (213) P > (213) PDGFR-P211 $$$$ csChFnd70/05150717532D 42 45 0 0 0 0 0 0 0 0999 V2000 4.2789 8.4037 0.0162 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1668 6.6917 -0.0031 N 0 0 0 0 0 0 0 0 0 0 0 0 4.3003 6.7761 0.0010 N 0 0 0 0 0 0 0 0 0 0 0 0 5.7878 9.2521 0.0223 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2631 8.3277 0.0120 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8443 10.9949 0.0380 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8544 10.7693 0.0318 C 0 0 0 0 0 0 0 0 0 0 0 0 10.1967 11.4447 0.0360 O 0 0 0 0 0 0 0 0 0 0 0 0 8.7637 9.1104 0.0170 N 0 0 3 0 0 0 0 0 0 0 0 0 7.3471 11.7653 0.0428 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4479 13.5901 0.0585 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4865 14.4664 -1.4227 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5799 16.1674 -1.3994 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6350 17.0024 0.0877 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5977 16.1411 1.5603 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4973 14.4402 1.5544 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4410 13.3621 3.4038 Cl 0 0 0 0 0 0 0 0 0 0 0 0 7.4182 13.4208 -3.2903 Cl 0 0 0 0 0 0 0 0 0 0 0 0 5.7138 5.9462 -0.0084 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6653 4.2424 -0.0242 N 0 0 3 0 0 0 0 0 0 0 0 0 4.1553 3.4214 0.1161 C 0 0 0 0 0 0 0 0 0 0 0 0 10.2830 8.1317 0.0068 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4046 1.1399 -0.5873 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8967 1.9505 -0.7254 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9149 4.0706 1.1015 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1656 1.7882 0.3883 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4194 3.2529 1.2371 C 0 0 0 0 0 0 0 0 0 0 0 0 0.2001 3.8883 2.1964 O 0 0 0 0 0 0 0 0 0 0 0 0 3.1245 9.0688 0.0183 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7189 11.7078 0.0455 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6104 16.8471 -2.5449 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7079 18.3325 0.0992 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6416 16.8003 2.7172 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6790 3.6161 -0.1325 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6583 7.9000 -1.2634 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2551 8.8064 0.6453 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0659 6.9606 0.6307 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2036 0.0000 -1.2470 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8630 1.4412 -1.4883 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1146 5.2105 1.7615 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 1.1516 0.4936 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2269 3.5116 3.3279 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 29 1 0 0 0 0 2 19 2 0 0 0 0 2 5 1 0 0 0 0 3 19 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 10 2 0 0 0 0 6 30 1 0 0 0 0 7 9 1 0 0 0 0 7 10 1 0 0 0 0 7 8 2 0 0 0 0 9 22 1 0 0 0 0 10 11 1 0 0 0 0 11 16 1 0 0 0 0 11 12 2 0 0 0 0 12 13 1 0 0 0 0 12 18 1 0 0 0 0 13 14 2 0 0 0 0 13 31 1 0 0 0 0 14 15 1 0 0 0 0 14 32 1 0 0 0 0 15 16 2 0 0 0 0 15 33 1 0 0 0 0 16 17 1 0 0 0 0 19 20 1 0 0 0 0 20 21 1 0 0 0 0 20 34 1 0 0 0 0 21 24 1 0 0 0 0 21 25 2 0 0 0 0 22 35 1 0 0 0 0 22 36 1 0 0 0 0 22 37 1 0 0 0 0 23 26 1 0 0 0 0 23 24 2 0 0 0 0 23 38 1 0 0 0 0 24 39 1 0 0 0 0 25 27 1 0 0 0 0 25 40 1 0 0 0 0 26 27 2 0 0 0 0 26 41 1 0 0 0 0 27 28 1 0 0 0 0 28 42 1 0 0 0 0 M END > (218) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 50 > (218) PDGFR-beta > (218) 410 > (218) -1 > (218) P > (218) PDGFR-P216 $$$$ Structure142 csChFnd70/05150717532D 68 71 0 0 0 0 0 0 0 0999 V2000 13.0718 9.6843 -0.1819 N 0 0 0 0 0 0 0 0 0 0 0 0 13.0900 7.9718 0.0535 C 0 0 0 0 0 0 0 0 0 0 0 0 14.5411 7.0702 0.1807 N 0 0 0 0 0 0 0 0 0 0 0 0 16.0829 7.8666 0.0741 C 0 0 0 0 0 0 0 0 0 0 0 0 16.1109 9.6927 -0.1774 C 0 0 0 0 0 0 0 0 0 0 0 0 17.5673 6.9826 0.1994 N 0 0 0 0 0 0 0 0 0 0 0 0 19.0853 7.7647 0.0954 C 0 0 0 0 0 0 0 0 0 0 0 0 19.2134 9.5751 -0.1536 C 0 0 0 0 0 0 0 0 0 0 0 0 20.5915 6.7863 0.2357 N 0 0 3 0 0 0 0 0 0 0 0 0 20.4916 5.0555 0.4739 C 0 0 0 0 0 0 0 0 0 0 0 0 21.9547 4.1052 0.6101 N 0 0 3 0 0 0 0 0 0 0 0 0 19.0816 4.3516 0.5661 O 0 0 0 0 0 0 0 0 0 0 0 0 11.5243 7.1029 0.1700 N 0 0 3 0 0 0 0 0 0 0 0 0 20.9397 10.4199 -0.2646 C 0 0 0 0 0 0 0 0 0 0 0 0 21.7502 11.0327 1.2345 C 0 0 0 0 0 0 0 0 0 0 0 0 23.3588 11.8180 1.1226 C 0 0 0 0 0 0 0 0 0 0 0 0 24.1656 11.9976 -0.4719 C 0 0 0 0 0 0 0 0 0 0 0 0 23.3686 11.3927 -1.9632 C 0 0 0 0 0 0 0 0 0 0 0 0 21.7634 10.5983 -1.8677 C 0 0 0 0 0 0 0 0 0 0 0 0 14.5227 10.5828 -0.3028 C 0 0 0 0 0 0 0 0 0 0 0 0 17.7119 10.5574 -0.2945 C 0 0 0 0 0 0 0 0 0 0 0 0 20.7656 9.8391 -3.7409 Cl 0 0 0 0 0 0 0 0 0 0 0 0 20.7391 10.8099 3.2369 Cl 0 0 0 0 0 0 0 0 0 0 0 0 21.8460 2.2237 0.8692 C 0 0 0 0 0 0 0 0 0 0 0 0 20.8790 1.3999 -0.6581 C 0 0 0 0 0 0 0 0 0 0 0 0 23.6781 1.4637 0.9804 C 0 0 0 0 0 0 0 0 0 0 0 0 20.8675 1.8429 2.5557 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5189 7.5162 0.0532 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1939 6.5869 0.0589 N 0 0 3 0 0 0 0 0 0 0 0 0 5.2184 5.4802 1.6325 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2704 5.2525 2.0783 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6556 7.8123 0.0622 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3628 6.8066 0.2044 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5434 6.9825 1.6193 N 0 0 3 0 0 0 0 0 0 0 0 0 9.8896 8.0661 0.0339 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6752 6.8637 1.2535 C 0 0 0 0 0 0 0 0 0 0 0 0 21.7164 7.3480 0.1623 H 0 0 0 0 0 0 0 0 0 0 0 0 23.0796 4.6667 0.5368 H 0 0 0 0 0 0 0 0 0 0 0 0 11.5077 5.8553 0.3419 H 0 0 0 0 0 0 0 0 0 0 0 0 23.9878 12.2931 2.2824 H 0 0 0 0 0 0 0 0 0 0 0 0 25.4228 12.6135 -0.5527 H 0 0 0 0 0 0 0 0 0 0 0 0 24.0049 11.5372 -3.2045 H 0 0 0 0 0 0 0 0 0 0 0 0 14.4922 11.9718 -0.4937 H 0 0 0 0 0 0 0 0 0 0 0 0 17.7714 11.9453 -0.4856 H 0 0 0 0 0 0 0 0 0 0 0 0 21.5759 1.6711 -1.8595 H 0 0 0 0 0 0 0 0 0 0 0 0 20.7980 0.0000 -0.4653 H 0 0 0 0 0 0 0 0 0 0 0 0 19.5736 1.9413 -0.7372 H 0 0 0 0 0 0 0 0 0 0 0 0 24.3671 2.0508 2.0685 H 0 0 0 0 0 0 0 0 0 0 0 0 23.5974 0.0640 1.1731 H 0 0 0 0 0 0 0 0 0 0 0 0 24.3753 1.7351 -0.2210 H 0 0 0 0 0 0 0 0 0 0 0 0 19.5623 2.3843 2.4764 H 0 0 0 0 0 0 0 0 0 0 0 0 20.7868 0.4432 2.7484 H 0 0 0 0 0 0 0 0 0 0 0 0 21.5566 2.4299 3.6437 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7457 8.9129 0.0831 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7851 7.1743 -1.1077 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8149 4.2279 1.3517 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8984 6.1316 2.6891 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6876 4.2345 1.2864 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0969 4.9824 3.4567 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6471 8.5600 -1.1395 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5322 8.6907 1.1651 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4247 6.1573 1.4604 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4294 5.8418 -0.8290 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8230 9.0308 1.0673 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8277 8.7153 -1.2222 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 6.3799 2.3994 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1776 8.1456 0.9188 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4619 5.9774 0.1709 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 20 2 0 0 0 0 2 3 2 0 0 0 0 2 13 1 0 0 0 0 3 4 1 0 0 0 0 4 6 2 0 0 0 0 4 5 1 0 0 0 0 5 20 1 0 0 0 0 5 21 2 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 7 9 1 0 0 0 0 8 14 1 0 0 0 0 8 21 1 0 0 0 0 9 10 1 0 0 0 0 9 37 1 0 0 0 0 10 11 1 0 0 0 0 10 12 2 0 0 0 0 11 24 1 0 0 0 0 11 38 1 0 0 0 0 13 35 1 0 0 0 0 13 39 1 0 0 0 0 14 15 2 0 0 0 0 14 19 1 0 0 0 0 15 16 1 0 0 0 0 15 23 1 0 0 0 0 16 17 2 0 0 0 0 16 40 1 0 0 0 0 17 18 1 0 0 0 0 17 41 1 0 0 0 0 18 19 2 0 0 0 0 18 42 1 0 0 0 0 19 22 1 0 0 0 0 20 43 1 0 0 0 0 21 44 1 0 0 0 0 24 25 1 0 0 0 0 24 26 1 0 0 0 0 24 27 1 0 0 0 0 25 45 1 0 0 0 0 25 46 1 0 0 0 0 25 47 1 0 0 0 0 26 48 1 0 0 0 0 26 49 1 0 0 0 0 26 50 1 0 0 0 0 27 51 1 0 0 0 0 27 52 1 0 0 0 0 27 53 1 0 0 0 0 28 29 1 0 0 0 0 28 34 1 0 0 0 0 28 54 1 0 0 0 0 28 55 1 0 0 0 0 29 30 1 0 0 0 0 29 32 1 0 0 0 0 30 31 1 0 0 0 0 30 56 1 0 0 0 0 30 57 1 0 0 0 0 31 34 1 0 0 0 0 31 58 1 0 0 0 0 31 59 1 0 0 0 0 32 33 1 0 0 0 0 32 60 1 0 0 0 0 32 61 1 0 0 0 0 33 35 1 0 0 0 0 33 62 1 0 0 0 0 33 63 1 0 0 0 0 34 36 1 0 0 0 0 35 64 1 0 0 0 0 35 65 1 0 0 0 0 36 66 1 0 0 0 0 36 67 1 0 0 0 0 36 68 1 0 0 0 0 M END > (245) 9240345-6b > (245) PDGFR-beta > (245) 470 > (245) -1 > (245) P > (245) PDGFR-P243 $$$$ csChFnd70/05150717532D 45 48 0 0 0 0 0 0 0 0999 V2000 6.4559 8.4044 0.0162 C 0 0 0 0 0 0 0 0 0 0 0 0 9.3438 6.6925 -0.0031 N 0 0 0 0 0 0 0 0 0 0 0 0 6.4773 6.7769 0.0010 N 0 0 0 0 0 0 0 0 0 0 0 0 7.9648 9.2529 0.0223 C 0 0 0 0 0 0 0 0 0 0 0 0 9.4401 8.3284 0.0120 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0213 10.9956 0.0380 C 0 0 0 0 0 0 0 0 0 0 0 0 11.0314 10.7700 0.0318 C 0 0 0 0 0 0 0 0 0 0 0 0 12.3737 11.4454 0.0365 O 0 0 0 0 0 0 0 0 0 0 0 0 10.9407 9.1111 0.0170 N 0 0 3 0 0 0 0 0 0 0 0 0 9.5241 11.7660 0.0428 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6249 13.5908 0.0591 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6633 14.4676 -1.4217 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7567 16.1686 -1.3979 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8120 17.0031 0.0894 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7749 16.1413 1.5617 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6745 14.4405 1.5553 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6186 13.3618 3.4044 Cl 0 0 0 0 0 0 0 0 0 0 0 0 9.5946 13.4227 -3.2897 Cl 0 0 0 0 0 0 0 0 0 0 0 0 7.8908 5.9469 -0.0084 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8423 4.2431 -0.0242 N 0 0 3 0 0 0 0 0 0 0 0 0 6.3323 3.4222 0.1161 C 0 0 0 0 0 0 0 0 0 0 0 0 12.4600 8.1324 0.0068 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5817 1.1404 -0.5869 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3426 1.7889 0.3883 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0737 1.9513 -0.7254 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0919 4.0714 1.1015 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5964 3.2537 1.2371 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3767 3.8896 2.1955 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8655 2.9854 2.2724 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3015 9.0695 0.0183 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8959 11.7085 0.0455 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7869 16.8488 -2.5431 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8849 18.3333 0.1013 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8190 16.8001 2.7188 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8560 3.6168 -0.1325 H 0 0 0 0 0 0 0 0 0 0 0 0 12.8353 7.9007 -1.2634 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4321 8.8072 0.6453 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2429 6.9614 0.6307 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3812 0.0000 -1.2458 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1772 1.1519 0.4942 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0397 1.4422 -1.4887 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2916 5.2112 1.7615 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 3.6266 3.0771 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3402 2.8847 1.0388 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1037 1.7551 2.7598 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 30 1 0 0 0 0 2 19 2 0 0 0 0 2 5 1 0 0 0 0 3 19 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 10 2 0 0 0 0 6 31 1 0 0 0 0 7 9 1 0 0 0 0 7 10 1 0 0 0 0 7 8 2 0 0 0 0 9 22 1 0 0 0 0 10 11 1 0 0 0 0 11 16 1 0 0 0 0 11 12 2 0 0 0 0 12 13 1 0 0 0 0 12 18 1 0 0 0 0 13 14 2 0 0 0 0 13 32 1 0 0 0 0 14 15 1 0 0 0 0 14 33 1 0 0 0 0 15 16 2 0 0 0 0 15 34 1 0 0 0 0 16 17 1 0 0 0 0 19 20 1 0 0 0 0 20 21 1 0 0 0 0 20 35 1 0 0 0 0 21 25 1 0 0 0 0 21 26 2 0 0 0 0 22 36 1 0 0 0 0 22 37 1 0 0 0 0 22 38 1 0 0 0 0 23 24 1 0 0 0 0 23 25 2 0 0 0 0 23 39 1 0 0 0 0 24 27 2 0 0 0 0 24 40 1 0 0 0 0 25 41 1 0 0 0 0 26 27 1 0 0 0 0 26 42 1 0 0 0 0 27 28 1 0 0 0 0 28 29 1 0 0 0 0 29 43 1 0 0 0 0 29 44 1 0 0 0 0 29 45 1 0 0 0 0 M END > (252) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 48 > (252) PDGFR-beta > (252) 530 > (252) -1 > (252) P > (252) PDGFR-P250 $$$$ 6-arylpyrido[2,3-d]pyrimidine deriv. 13 csChFnd70/05150717532D 68 70 0 0 0 0 0 0 0 0999 V2000 7.3687 12.7410 0.5075 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1677 9.8508 0.4293 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1324 13.1932 0.6252 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3912 11.8462 0.6384 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6769 14.9309 0.7300 C 0 0 0 0 0 0 0 0 0 0 0 0 12.6194 13.8509 0.8491 C 0 0 0 0 0 0 0 0 0 0 0 0 11.4430 15.2561 0.8431 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9557 11.0829 0.4140 N 0 0 0 0 0 0 0 0 0 0 0 0 9.8418 10.2001 0.5377 N 0 0 0 0 0 0 0 0 0 0 0 0 12.0770 12.2316 0.7494 N 0 0 0 0 0 0 0 0 0 0 0 0 12.0915 17.0652 0.9562 C 0 0 0 0 0 0 0 0 0 0 0 0 12.9147 19.5396 2.6689 C 0 0 0 0 0 0 0 0 0 0 0 0 12.3101 17.8537 2.5723 C 0 0 0 0 0 0 0 0 0 0 0 0 12.4928 17.9835 -0.5525 C 0 0 0 0 0 0 0 0 0 0 0 0 13.0963 19.6688 -0.4385 C 0 0 0 0 0 0 0 0 0 0 0 0 13.3037 20.4456 1.1676 C 0 0 0 0 0 0 0 0 0 0 0 0 11.8225 16.7187 4.4579 Cl 0 0 0 0 0 0 0 0 0 0 0 0 12.2348 17.0103 -2.5695 Cl 0 0 0 0 0 0 0 0 0 0 0 0 7.6515 8.1350 0.3276 N 0 0 3 0 0 0 0 0 0 0 0 0 5.8028 7.7035 0.2059 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5883 5.7306 0.1101 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6575 5.2799 -0.0169 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4514 3.3857 -0.1088 N 0 0 0 0 0 0 0 0 0 0 0 0 4.0046 2.5580 1.5184 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2739 0.6133 1.2140 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6540 2.9137 -0.5393 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3365 3.2139 -2.4773 C 0 0 0 0 0 0 0 0 0 0 0 0 14.3866 14.1823 0.9625 N 0 0 3 0 0 0 0 0 0 0 0 0 15.5271 12.8548 0.9698 C 0 0 0 0 0 0 0 0 0 0 0 0 15.0074 11.3671 0.8769 O 0 0 0 0 0 0 0 0 0 0 0 0 17.2439 13.1767 1.0799 N 0 0 3 0 0 0 0 0 0 0 0 0 18.2975 10.6916 -0.5934 C 0 0 0 0 0 0 0 0 0 0 0 0 20.3321 12.4495 1.2222 C 0 0 0 0 0 0 0 0 0 0 0 0 18.4836 11.7338 1.0878 C 0 0 0 0 0 0 0 0 0 0 0 0 18.1158 10.5533 2.6429 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3739 13.7295 0.4997 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7476 15.9813 0.7224 H 0 0 0 0 0 0 0 0 0 0 0 0 13.0844 20.1514 3.9193 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4075 20.3812 -1.6058 H 0 0 0 0 0 0 0 0 0 0 0 0 13.7761 21.7635 1.2500 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5135 7.2165 0.3367 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1270 8.1967 1.3478 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2559 8.2946 -0.9579 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2639 5.2374 -1.0316 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1352 5.1394 1.2741 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9817 5.7731 1.1249 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1105 5.8710 -1.1808 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2188 3.1399 1.9547 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0089 2.7475 2.5063 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0263 0.0000 0.9483 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1376 0.4238 0.1088 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8498 0.0304 2.3682 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4380 1.5490 -0.2317 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7626 3.7141 0.2144 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 2.8728 -2.7950 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5619 4.5765 -2.7869 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2214 2.4062 -3.2312 H 0 0 0 0 0 0 0 0 0 0 0 0 14.8013 15.3693 1.0365 H 0 0 0 0 0 0 0 0 0 0 0 0 17.6585 14.3637 1.1539 H 0 0 0 0 0 0 0 0 0 0 0 0 18.5596 11.5326 -1.7014 H 0 0 0 0 0 0 0 0 0 0 0 0 19.2200 9.6181 -0.5876 H 0 0 0 0 0 0 0 0 0 0 0 0 16.9807 10.1816 -0.6891 H 0 0 0 0 0 0 0 0 0 0 0 0 20.4645 13.1920 2.4200 H 0 0 0 0 0 0 0 0 0 0 0 0 21.2544 11.3760 1.2280 H 0 0 0 0 0 0 0 0 0 0 0 0 20.5940 13.2906 0.1143 H 0 0 0 0 0 0 0 0 0 0 0 0 16.7990 10.0433 2.5472 H 0 0 0 0 0 0 0 0 0 0 0 0 19.0383 9.4796 2.6488 H 0 0 0 0 0 0 0 0 0 0 0 0 18.2484 11.2958 3.8407 H 0 0 0 0 0 0 0 0 0 0 0 0 1 8 1 0 0 0 0 1 3 2 0 0 0 0 1 36 1 0 0 0 0 2 8 2 0 0 0 0 2 9 1 0 0 0 0 2 19 1 0 0 0 0 3 5 1 0 0 0 0 3 4 1 0 0 0 0 4 9 2 0 0 0 0 4 10 1 0 0 0 0 5 7 2 0 0 0 0 5 37 1 0 0 0 0 6 10 2 0 0 0 0 6 7 1 0 0 0 0 6 28 1 0 0 0 0 7 11 1 0 0 0 0 11 13 1 0 0 0 0 11 14 2 0 0 0 0 12 13 2 0 0 0 0 12 16 1 0 0 0 0 12 38 1 0 0 0 0 13 17 1 0 0 0 0 14 15 1 0 0 0 0 14 18 1 0 0 0 0 15 16 2 0 0 0 0 15 39 1 0 0 0 0 16 40 1 0 0 0 0 19 20 1 0 0 0 0 19 41 1 0 0 0 0 20 21 1 0 0 0 0 20 42 1 0 0 0 0 20 43 1 0 0 0 0 21 22 1 0 0 0 0 21 44 1 0 0 0 0 21 45 1 0 0 0 0 22 23 1 0 0 0 0 22 46 1 0 0 0 0 22 47 1 0 0 0 0 23 24 1 0 0 0 0 23 26 1 0 0 0 0 24 25 1 0 0 0 0 24 48 1 0 0 0 0 24 49 1 0 0 0 0 25 50 1 0 0 0 0 25 51 1 0 0 0 0 25 52 1 0 0 0 0 26 27 1 0 0 0 0 26 53 1 0 0 0 0 26 54 1 0 0 0 0 27 55 1 0 0 0 0 27 56 1 0 0 0 0 27 57 1 0 0 0 0 28 29 1 0 0 0 0 28 58 1 0 0 0 0 29 31 1 0 0 0 0 29 30 2 0 0 0 0 31 34 1 0 0 0 0 31 59 1 0 0 0 0 32 34 1 0 0 0 0 32 60 1 0 0 0 0 32 61 1 0 0 0 0 32 62 1 0 0 0 0 33 34 1 0 0 0 0 33 63 1 0 0 0 0 33 64 1 0 0 0 0 33 65 1 0 0 0 0 34 35 1 0 0 0 0 35 66 1 0 0 0 0 35 67 1 0 0 0 0 35 68 1 0 0 0 0 M END > (279) 6-arylpyrido[2,3-d]pyrimidine deriv. 13 > (279) PDGFR-beta > (279) 660 > (279) -1 > (279) P > (279) PDGFR-P277 $$$$ csChFnd70/05150717532D 45 48 0 0 0 0 0 0 0 0999 V2000 6.7679 8.2220 0.0163 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5937 6.5471 -0.0029 N 0 0 0 0 0 0 0 0 0 0 0 0 6.7889 6.6295 0.0013 N 0 0 0 0 0 0 0 0 0 0 0 0 8.2444 9.0522 0.0223 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6879 8.1477 0.0121 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2995 10.7573 0.0378 C 0 0 0 0 0 0 0 0 0 0 0 0 11.2448 10.5368 0.0316 C 0 0 0 0 0 0 0 0 0 0 0 0 12.5582 11.1977 0.0357 O 0 0 0 0 0 0 0 0 0 0 0 0 11.1562 8.9136 0.0170 N 0 0 3 0 0 0 0 0 0 0 0 0 9.7701 11.5111 0.0425 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8685 13.2966 0.0579 C 0 0 0 0 0 0 0 0 0 0 0 0 9.9062 14.1542 -1.3910 C 0 0 0 0 0 0 0 0 0 0 0 0 9.9975 15.8186 -1.3682 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0514 16.6354 0.0869 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0145 15.7925 1.5277 C 0 0 0 0 0 0 0 0 0 0 0 0 9.9169 14.1283 1.5217 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8617 13.0733 3.3312 Cl 0 0 0 0 0 0 0 0 0 0 0 0 9.8394 13.1314 -3.2185 Cl 0 0 0 0 0 0 0 0 0 0 0 0 8.1719 5.8175 -0.0080 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1246 4.1509 -0.0236 N 0 0 3 0 0 0 0 0 0 0 0 0 6.6448 3.3463 0.1137 C 0 0 0 0 0 0 0 0 0 0 0 0 12.6427 7.9561 0.0067 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9329 1.1154 -0.5733 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3928 1.9081 -0.7093 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4309 3.9824 1.0787 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9718 3.1882 1.2134 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7185 1.7552 0.3853 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2812 0.9741 0.5183 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0849 1.7015 1.5256 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6385 8.8727 0.0183 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1984 11.4548 0.0451 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0272 16.4838 -2.4889 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1232 17.9368 0.0982 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0574 16.4374 2.6597 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1165 3.5381 -0.1297 H 0 0 0 0 0 0 0 0 0 0 0 0 13.0098 7.7294 -1.2361 H 0 0 0 0 0 0 0 0 0 0 0 0 13.5938 8.6162 0.6316 H 0 0 0 0 0 0 0 0 0 0 0 0 12.4304 6.8102 0.6172 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7347 0.0000 -1.2181 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3380 1.4101 -1.4561 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6280 5.0978 1.7238 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0256 3.6856 1.9595 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5475 1.8019 2.7531 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7949 2.8999 1.0668 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 0.9574 1.5254 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 30 1 0 0 0 0 2 19 2 0 0 0 0 2 5 1 0 0 0 0 3 19 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 10 2 0 0 0 0 6 31 1 0 0 0 0 7 9 1 0 0 0 0 7 10 1 0 0 0 0 7 8 2 0 0 0 0 9 22 1 0 0 0 0 10 11 1 0 0 0 0 11 16 1 0 0 0 0 11 12 2 0 0 0 0 12 13 1 0 0 0 0 12 18 1 0 0 0 0 13 14 2 0 0 0 0 13 32 1 0 0 0 0 14 15 1 0 0 0 0 14 33 1 0 0 0 0 15 16 2 0 0 0 0 15 34 1 0 0 0 0 16 17 1 0 0 0 0 19 20 1 0 0 0 0 20 21 1 0 0 0 0 20 35 1 0 0 0 0 21 24 1 0 0 0 0 21 25 2 0 0 0 0 22 36 1 0 0 0 0 22 37 1 0 0 0 0 22 38 1 0 0 0 0 23 27 1 0 0 0 0 23 24 2 0 0 0 0 23 39 1 0 0 0 0 24 40 1 0 0 0 0 25 26 1 0 0 0 0 25 41 1 0 0 0 0 26 27 2 0 0 0 0 26 42 1 0 0 0 0 27 28 1 0 0 0 0 28 29 1 0 0 0 0 29 43 1 0 0 0 0 29 44 1 0 0 0 0 29 45 1 0 0 0 0 M END > (282) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 49 > (282) PDGFR-beta > (282) 680 > (282) -1 > (282) P > (282) PDGFR-P280 $$$$ Indolin-2-one deriv. 9g csChFnd70/05150717532D 59 63 0 0 0 0 0 0 0 0999 V2000 5.8611 9.4248 0.1582 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8807 7.8397 0.2069 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2821 7.0530 0.1933 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6644 7.8615 0.1308 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6549 9.4584 0.0821 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2407 10.2391 0.0957 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6100 11.9006 0.0331 C 0 0 0 0 0 0 0 0 0 0 0 0 9.2987 11.9752 -0.0153 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8439 10.5276 0.0165 N 0 0 3 0 0 0 0 0 0 0 0 0 10.0702 13.1449 -0.0740 O 0 0 0 0 0 0 0 0 0 0 0 0 6.5868 13.1195 0.0220 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1366 14.6418 0.1467 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5037 15.9355 -0.5469 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3981 15.1198 0.9860 N 0 0 3 0 0 0 0 0 0 0 0 0 5.1043 15.9774 -1.5718 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6643 16.2307 -0.5895 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2650 16.2726 -1.6144 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4051 16.1159 -2.9896 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8628 16.4839 -0.9996 O 0 0 0 0 0 0 0 0 0 0 0 0 8.5528 16.6603 0.8163 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4063 17.1851 -0.1155 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1969 18.8500 -0.5637 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7722 17.6812 1.5199 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7876 19.2146 0.6454 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1461 19.8478 0.5414 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2983 5.3463 0.2464 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9189 4.5304 0.3029 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9418 2.9363 0.3523 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3367 2.1564 0.3460 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7063 2.9658 0.2904 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6943 4.5537 0.2332 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5984 2.1360 0.4076 O 0 0 0 0 0 0 0 0 0 0 0 0 4.7079 0.4951 0.4565 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7774 10.0348 0.1635 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8121 7.2058 0.2558 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7446 7.2457 0.1207 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9286 10.2626 -0.0040 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3663 12.9059 -0.0823 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0627 14.4612 1.5959 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2182 16.9160 -2.3971 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0043 14.8886 -2.1879 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5505 15.2921 0.2358 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7644 17.3195 0.0266 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.5024 -1.7031 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5970 19.0246 -1.7403 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9842 19.1615 -0.4785 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5052 17.8868 2.7288 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8943 17.1278 1.4225 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5137 20.0364 1.2556 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2423 19.0324 -0.5099 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1780 21.0283 0.1165 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6199 19.8272 1.6805 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8344 5.1388 0.3087 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3521 0.9136 0.3850 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7886 2.3534 0.2864 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7659 5.1824 0.1837 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3029 0.0847 -0.5693 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3490 0.1490 1.4785 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5555 0.0000 0.4980 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 6 2 0 0 0 0 1 34 1 0 0 0 0 2 3 2 0 0 0 0 2 35 1 0 0 0 0 3 4 1 0 0 0 0 3 26 1 0 0 0 0 4 5 2 0 0 0 0 4 36 1 0 0 0 0 5 9 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 9 1 0 0 0 0 8 10 2 0 0 0 0 9 37 1 0 0 0 0 11 12 1 0 0 0 0 11 38 1 0 0 0 0 12 13 2 0 0 0 0 12 14 1 0 0 0 0 13 21 1 0 0 0 0 13 15 1 0 0 0 0 14 20 1 0 0 0 0 14 39 1 0 0 0 0 15 16 1 0 0 0 0 15 40 1 0 0 0 0 15 41 1 0 0 0 0 16 17 1 0 0 0 0 16 42 1 0 0 0 0 16 43 1 0 0 0 0 17 19 1 0 0 0 0 17 18 2 0 0 0 0 19 44 1 0 0 0 0 20 23 1 0 0 0 0 20 21 2 0 0 0 0 21 22 1 0 0 0 0 22 25 1 0 0 0 0 22 45 1 0 0 0 0 22 46 1 0 0 0 0 23 24 1 0 0 0 0 23 47 1 0 0 0 0 23 48 1 0 0 0 0 24 25 1 0 0 0 0 24 49 1 0 0 0 0 24 50 1 0 0 0 0 25 51 1 0 0 0 0 25 52 1 0 0 0 0 26 31 1 0 0 0 0 26 27 2 0 0 0 0 27 28 1 0 0 0 0 27 53 1 0 0 0 0 28 29 2 0 0 0 0 28 32 1 0 0 0 0 29 30 1 0 0 0 0 29 54 1 0 0 0 0 30 31 2 0 0 0 0 30 55 1 0 0 0 0 31 56 1 0 0 0 0 32 33 1 0 0 0 0 33 57 1 0 0 0 0 33 58 1 0 0 0 0 33 59 1 0 0 0 0 M END > (285) Indolin-2-one deriv. 9g > (285) PDGFR-beta > (285) 680 > (285) -1 > (285) P > (285) PDGFR-P283 $$$$ csChFnd70/05150717532D 63 66 0 0 0 0 0 0 0 0999 V2000 5.3737 18.8994 0.0120 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4091 17.1016 -0.0266 N 0 0 0 0 0 0 0 0 0 0 0 0 5.3969 17.1887 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 6.9590 19.7917 0.0017 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5097 18.8210 -0.0183 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0174 21.6234 0.0104 C 0 0 0 0 0 0 0 0 0 0 0 0 10.1807 21.3878 -0.0216 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5911 22.0982 -0.0319 O 0 0 0 0 0 0 0 0 0 0 0 0 10.0862 19.6443 -0.0296 N 0 0 3 0 0 0 0 0 0 0 0 0 11.6831 18.6165 -0.0497 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5964 22.4337 -0.0009 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7014 24.3516 0.0083 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7280 25.2675 -1.5515 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8255 27.0552 -1.5337 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8972 27.9378 0.0257 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8719 27.0377 1.5764 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7666 25.2502 1.5769 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7255 24.1234 3.5247 Cl 0 0 0 0 0 0 0 0 0 0 0 0 8.6396 24.1622 -3.5098 Cl 0 0 0 0 0 0 0 0 0 0 0 0 6.8826 16.3173 -0.0162 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8325 14.5281 -0.0259 N 0 0 3 0 0 0 0 0 0 0 0 0 5.1619 13.6250 -0.0156 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4697 11.6655 -0.0296 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7250 10.7222 -0.0187 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0326 8.7627 -0.0327 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2880 7.8194 -0.0218 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3044 3.0399 0.1568 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9619 4.9901 0.2834 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9174 5.4474 1.2332 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2598 3.4972 1.1067 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5834 5.9382 -0.0352 N 0 0 0 0 0 0 0 0 0 0 0 0 2.6384 2.5491 1.4254 N 0 0 0 0 0 0 0 0 0 0 0 0 2.9338 0.6679 1.4119 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1603 19.5978 0.0216 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8345 22.3721 0.0253 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0664 18.3679 -1.3869 H 0 0 0 0 0 0 0 0 0 0 0 0 12.7100 19.3286 0.6099 H 0 0 0 0 0 0 0 0 0 0 0 0 11.4611 17.3882 0.6128 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8461 27.7656 -2.7400 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9738 29.3358 0.0324 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9288 27.7344 2.7896 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9035 13.8693 -0.0398 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4416 13.9803 1.1470 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4201 13.9934 -1.1603 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1899 11.3101 -1.1921 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2116 11.2970 1.1151 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0046 11.0776 1.1439 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9831 11.0907 -1.1634 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7530 8.4074 -1.1953 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7746 8.3943 1.1120 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5676 8.1747 1.1408 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5461 8.1879 -1.1666 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1116 2.3331 0.4298 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7530 2.7234 -1.1452 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 5.3634 -0.6820 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4798 5.3013 1.5747 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4688 5.7638 2.5353 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1102 6.1542 0.9604 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7419 3.1860 -0.1846 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2217 3.1239 2.0721 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3622 0.2676 0.1261 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9267 0.3402 2.3624 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7318 0.0000 1.7372 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 34 1 0 0 0 0 2 20 2 0 0 0 0 2 5 1 0 0 0 0 3 20 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 11 2 0 0 0 0 6 35 1 0 0 0 0 7 9 1 0 0 0 0 7 11 1 0 0 0 0 7 8 2 0 0 0 0 9 10 1 0 0 0 0 10 36 1 0 0 0 0 10 37 1 0 0 0 0 10 38 1 0 0 0 0 11 12 1 0 0 0 0 12 17 1 0 0 0 0 12 13 2 0 0 0 0 13 14 1 0 0 0 0 13 19 1 0 0 0 0 14 15 2 0 0 0 0 14 39 1 0 0 0 0 15 16 1 0 0 0 0 15 40 1 0 0 0 0 16 17 2 0 0 0 0 16 41 1 0 0 0 0 17 18 1 0 0 0 0 20 21 1 0 0 0 0 21 22 1 0 0 0 0 21 42 1 0 0 0 0 22 23 1 0 0 0 0 22 43 1 0 0 0 0 22 44 1 0 0 0 0 23 24 1 0 0 0 0 23 45 1 0 0 0 0 23 46 1 0 0 0 0 24 25 1 0 0 0 0 24 47 1 0 0 0 0 24 48 1 0 0 0 0 25 26 1 0 0 0 0 25 49 1 0 0 0 0 25 50 1 0 0 0 0 26 31 1 0 0 0 0 26 51 1 0 0 0 0 26 52 1 0 0 0 0 27 32 1 0 0 0 0 27 28 1 0 0 0 0 27 53 1 0 0 0 0 27 54 1 0 0 0 0 28 31 1 0 0 0 0 28 55 1 0 0 0 0 28 56 1 0 0 0 0 29 31 1 0 0 0 0 29 30 1 0 0 0 0 29 57 1 0 0 0 0 29 58 1 0 0 0 0 30 32 1 0 0 0 0 30 59 1 0 0 0 0 30 60 1 0 0 0 0 32 33 1 0 0 0 0 33 61 1 0 0 0 0 33 62 1 0 0 0 0 33 63 1 0 0 0 0 M END > (293) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 33 > (293) PDGFR-beta > (293) 710 > (293) -1 > (293) P > (293) PDGFR-P291 $$$$ csChFnd70/05150717532D 49 51 0 0 0 0 0 0 0 0999 V2000 4.1360 15.3286 0.0120 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1711 13.5309 -0.0266 N 0 0 0 0 0 0 0 0 0 0 0 0 4.1592 13.6180 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 5.7211 16.2208 0.0017 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2717 15.2501 -0.0183 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7796 18.0523 0.0104 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9426 17.8168 -0.0216 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3528 18.5271 -0.0319 O 0 0 0 0 0 0 0 0 0 0 0 0 8.8481 16.0734 -0.0296 N 0 0 3 0 0 0 0 0 0 0 0 0 10.4448 15.0457 -0.0496 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3584 18.8626 -0.0009 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4634 20.7803 0.0083 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4900 21.6961 -1.5514 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5875 23.4837 -1.5336 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6592 24.3662 0.0257 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6339 23.4662 1.5763 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5286 21.6789 1.5768 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4875 20.5522 3.5244 Cl 0 0 0 0 0 0 0 0 0 0 0 0 7.4016 20.5909 -3.5095 Cl 0 0 0 0 0 0 0 0 0 0 0 0 5.6447 12.7467 -0.0162 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5947 10.9577 -0.0259 N 0 0 3 0 0 0 0 0 0 0 0 0 3.9242 10.0546 -0.0156 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2319 8.0952 -0.0296 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4874 7.1521 -0.0187 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7950 5.1927 -0.0327 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0505 4.2495 -0.0218 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8150 1.7566 -0.0525 O 0 0 0 0 0 0 0 0 0 0 0 0 1.3536 2.3197 -0.0356 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 1.2264 -0.0292 O 0 0 0 0 0 0 0 0 0 0 0 0 2.9227 16.0269 0.0216 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5967 18.8010 0.0253 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8282 14.7971 -1.3868 H 0 0 0 0 0 0 0 0 0 0 0 0 11.4716 15.7578 0.6099 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2229 13.8175 0.6127 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6081 24.1941 -2.7398 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7358 25.7641 0.0324 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6908 24.1628 2.7893 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6656 10.2989 -0.0398 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2040 10.4099 1.1469 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1825 10.4230 -1.1602 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9522 7.7399 -1.1920 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9738 7.7268 1.1150 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7671 7.5074 1.1438 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7456 7.5205 -1.1633 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5154 4.8374 -1.1952 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5369 4.8244 1.1119 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3302 4.6048 1.1407 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3087 4.6180 -1.1665 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2590 0.0000 -0.0386 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 30 1 0 0 0 0 2 20 2 0 0 0 0 2 5 1 0 0 0 0 3 20 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 11 2 0 0 0 0 6 31 1 0 0 0 0 7 9 1 0 0 0 0 7 11 1 0 0 0 0 7 8 2 0 0 0 0 9 10 1 0 0 0 0 10 32 1 0 0 0 0 10 33 1 0 0 0 0 10 34 1 0 0 0 0 11 12 1 0 0 0 0 12 17 1 0 0 0 0 12 13 2 0 0 0 0 13 14 1 0 0 0 0 13 19 1 0 0 0 0 14 15 2 0 0 0 0 14 35 1 0 0 0 0 15 16 1 0 0 0 0 15 36 1 0 0 0 0 16 17 2 0 0 0 0 16 37 1 0 0 0 0 17 18 1 0 0 0 0 20 21 1 0 0 0 0 21 22 1 0 0 0 0 21 38 1 0 0 0 0 22 23 1 0 0 0 0 22 39 1 0 0 0 0 22 40 1 0 0 0 0 23 24 1 0 0 0 0 23 41 1 0 0 0 0 23 42 1 0 0 0 0 24 25 1 0 0 0 0 24 43 1 0 0 0 0 24 44 1 0 0 0 0 25 26 1 0 0 0 0 25 45 1 0 0 0 0 25 46 1 0 0 0 0 26 28 1 0 0 0 0 26 47 1 0 0 0 0 26 48 1 0 0 0 0 27 28 2 0 0 0 0 28 29 1 0 0 0 0 29 49 1 0 0 0 0 M END > (297) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 37 > (297) PDGFR-beta > (297) 730 > (297) -1 > (297) P > (297) PDGFR-P295 $$$$ csChFnd70/05150717532D 44 47 0 0 0 0 0 0 0 0999 V2000 4.2846 8.4107 0.0168 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1759 6.6967 -0.0028 N 0 0 0 0 0 0 0 0 0 0 0 0 4.3060 6.7811 0.0014 N 0 0 0 0 0 0 0 0 0 0 0 0 5.7953 9.2601 0.0230 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2724 8.3346 0.0125 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8518 11.0049 0.0388 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8655 10.7791 0.0352 C 0 0 0 0 0 0 0 0 0 0 0 0 10.2095 11.4551 0.0415 O 0 0 0 0 0 0 0 0 0 0 0 0 8.7749 9.1181 0.0186 N 0 0 3 0 0 0 0 0 0 0 0 0 7.3565 11.7763 0.0437 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4574 13.6033 0.0608 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4956 14.4817 -1.4213 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5897 16.1848 -1.3967 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6461 17.0195 0.0928 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6092 16.1560 1.5664 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5075 14.4532 1.5591 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4509 13.3724 3.4100 Cl 0 0 0 0 0 0 0 0 0 0 0 0 7.4257 13.4365 -3.2920 Cl 0 0 0 0 0 0 0 0 0 0 0 0 5.7211 5.9502 -0.0081 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6725 4.2445 -0.0248 N 0 0 3 0 0 0 0 0 0 0 0 0 4.1608 3.4224 0.1150 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1682 1.7954 0.3916 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4062 1.1417 -0.5866 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9013 1.9506 -0.7274 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9171 4.0719 1.1021 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4250 3.2567 1.2375 C 0 0 0 0 0 0 0 0 0 0 0 0 10.2958 8.1383 0.0075 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8236 7.8146 -1.7778 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1289 9.0766 0.0190 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7250 11.7187 0.0464 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6199 16.8663 -2.5430 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7196 18.3513 0.1052 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6541 16.8150 2.7252 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6875 3.6173 -0.1334 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 1.1606 0.4992 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2020 0.0000 -1.2453 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8674 1.4397 -1.4919 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1169 5.2129 1.7635 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4555 3.7639 2.0005 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2690 8.8131 0.6478 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0785 6.9652 0.6310 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8503 7.1398 -2.4181 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0409 8.9878 -2.4012 H 0 0 0 0 0 0 0 0 0 0 0 0 11.9552 7.0856 -1.7860 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 29 1 0 0 0 0 2 19 2 0 0 0 0 2 5 1 0 0 0 0 3 19 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 10 2 0 0 0 0 6 30 1 0 0 0 0 7 9 1 0 0 0 0 7 10 1 0 0 0 0 7 8 2 0 0 0 0 9 27 1 0 0 0 0 10 11 1 0 0 0 0 11 16 1 0 0 0 0 11 12 2 0 0 0 0 12 13 1 0 0 0 0 12 18 1 0 0 0 0 13 14 2 0 0 0 0 13 31 1 0 0 0 0 14 15 1 0 0 0 0 14 32 1 0 0 0 0 15 16 2 0 0 0 0 15 33 1 0 0 0 0 16 17 1 0 0 0 0 19 20 1 0 0 0 0 20 21 1 0 0 0 0 20 34 1 0 0 0 0 21 24 1 0 0 0 0 21 25 2 0 0 0 0 22 23 1 0 0 0 0 22 26 2 0 0 0 0 22 35 1 0 0 0 0 23 24 2 0 0 0 0 23 36 1 0 0 0 0 24 37 1 0 0 0 0 25 26 1 0 0 0 0 25 38 1 0 0 0 0 26 39 1 0 0 0 0 27 28 1 0 0 0 0 27 40 1 0 0 0 0 27 41 1 0 0 0 0 28 42 1 0 0 0 0 28 43 1 0 0 0 0 28 44 1 0 0 0 0 M END > (314) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 39 > (314) PDGFR-beta > (314) 800 > (314) -1 > (314) P > (314) PDGFR-P312 $$$$ Indolin-2-one deriv. 9d csChFnd70/05150717532D 48 51 0 0 0 0 0 0 0 0999 V2000 5.7174 4.6178 -0.1496 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6905 3.0271 -0.3930 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8982 2.3190 -1.1947 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1121 3.1783 -1.7442 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1531 4.7668 -1.5093 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9424 5.4807 -0.7056 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3198 7.1442 -0.6496 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7960 7.2859 -1.4656 C 0 0 0 0 0 0 0 0 0 0 0 0 9.2217 5.8734 -1.9367 N 0 0 3 0 0 0 0 0 0 0 0 0 9.5102 8.4762 -1.6775 O 0 0 0 0 0 0 0 0 0 0 0 0 6.4680 8.3096 0.0235 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0867 9.8089 0.1337 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2666 11.1801 0.0447 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6171 10.1812 0.3564 N 0 0 3 0 0 0 0 0 0 0 0 0 4.5530 11.3468 -0.1863 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7483 11.3749 1.3828 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0346 11.5416 1.1517 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5107 11.6290 -0.1358 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0901 11.5929 2.3764 O 0 0 0 0 0 0 0 0 0 0 0 0 8.7499 11.7344 0.3970 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3271 12.3704 0.2100 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0141 14.0810 0.1994 C 0 0 0 0 0 0 0 0 0 0 0 0 10.2063 12.6639 0.6130 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8879 14.3262 0.1041 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4172 14.9088 0.8859 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3941 2.0963 0.1931 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3471 2.7136 0.8891 O 0 0 0 0 0 0 0 0 0 0 0 0 4.3709 0.5613 -0.0433 O 0 0 0 0 0 0 0 0 0 0 0 0 4.7871 5.1733 0.4634 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8771 1.0884 -1.3828 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0380 2.6193 -2.3605 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1602 5.6558 -2.5045 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3286 8.0724 0.4652 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4570 9.4513 0.4660 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3152 12.4181 -0.7983 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1247 10.3761 -0.8594 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9861 10.3036 1.9947 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1765 12.3456 2.0559 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 11.7008 2.1705 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8288 14.4700 -0.9809 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9956 14.3290 0.8922 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5419 12.6490 1.8236 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1275 12.1758 -0.0882 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8543 15.0577 0.4350 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7442 14.3618 -1.1436 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3049 16.1466 0.7012 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4808 14.6733 2.1184 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4974 0.0000 0.3623 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 6 2 0 0 0 0 1 29 1 0 0 0 0 2 3 2 0 0 0 0 2 26 1 0 0 0 0 3 4 1 0 0 0 0 3 30 1 0 0 0 0 4 5 2 0 0 0 0 4 31 1 0 0 0 0 5 9 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 9 1 0 0 0 0 8 10 2 0 0 0 0 9 32 1 0 0 0 0 11 12 1 0 0 0 0 11 33 1 0 0 0 0 12 13 2 0 0 0 0 12 14 1 0 0 0 0 13 21 1 0 0 0 0 13 15 1 0 0 0 0 14 20 1 0 0 0 0 14 34 1 0 0 0 0 15 16 1 0 0 0 0 15 35 1 0 0 0 0 15 36 1 0 0 0 0 16 17 1 0 0 0 0 16 37 1 0 0 0 0 16 38 1 0 0 0 0 17 19 1 0 0 0 0 17 18 2 0 0 0 0 19 39 1 0 0 0 0 20 23 1 0 0 0 0 20 21 2 0 0 0 0 21 22 1 0 0 0 0 22 25 1 0 0 0 0 22 40 1 0 0 0 0 22 41 1 0 0 0 0 23 24 1 0 0 0 0 23 42 1 0 0 0 0 23 43 1 0 0 0 0 24 25 1 0 0 0 0 24 44 1 0 0 0 0 24 45 1 0 0 0 0 25 46 1 0 0 0 0 25 47 1 0 0 0 0 26 27 2 0 0 0 0 26 28 1 0 0 0 0 28 48 1 0 0 0 0 M END > (33) Indolin-2-one deriv. 9d > (33) PDGFR-beta > (33) 20 > (33) -1 > (33) P > (33) PDGFR-P31 $$$$ csChFnd70/05150717532D 60 63 0 0 0 0 0 0 0 0999 V2000 8.2802 15.3170 0.0120 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3156 13.5192 -0.0266 N 0 0 0 0 0 0 0 0 0 0 0 0 8.3034 13.6063 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 9.8654 16.2093 0.0017 C 0 0 0 0 0 0 0 0 0 0 0 0 11.4162 15.2386 -0.0183 C 0 0 0 0 0 0 0 0 0 0 0 0 9.9239 18.0410 0.0104 C 0 0 0 0 0 0 0 0 0 0 0 0 13.0872 17.8054 -0.0216 C 0 0 0 0 0 0 0 0 0 0 0 0 14.4975 18.5158 -0.0319 O 0 0 0 0 0 0 0 0 0 0 0 0 12.9927 16.0619 -0.0296 N 0 0 3 0 0 0 0 0 0 0 0 0 14.5896 15.0341 -0.0497 C 0 0 0 0 0 0 0 0 0 0 0 0 11.5029 18.8513 -0.0009 C 0 0 0 0 0 0 0 0 0 0 0 0 11.6079 20.7692 0.0083 C 0 0 0 0 0 0 0 0 0 0 0 0 11.6345 21.6851 -1.5515 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7320 23.4728 -1.5337 C 0 0 0 0 0 0 0 0 0 0 0 0 11.8037 24.3554 0.0257 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7784 23.4553 1.5764 C 0 0 0 0 0 0 0 0 0 0 0 0 11.6731 21.6678 1.5769 C 0 0 0 0 0 0 0 0 0 0 0 0 11.6320 20.5410 3.5247 Cl 0 0 0 0 0 0 0 0 0 0 0 0 11.5461 20.5798 -3.5098 Cl 0 0 0 0 0 0 0 0 0 0 0 0 9.7891 12.7349 -0.0162 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7390 10.9457 -0.0259 N 0 0 3 0 0 0 0 0 0 0 0 0 8.0684 10.0426 -0.0156 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3762 8.0831 -0.0296 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6315 7.1398 -0.0187 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9391 5.1803 -0.0327 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7349 1.5006 -0.2204 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4935 2.4109 -0.3438 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0660 5.0401 -1.2904 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3074 4.1298 -1.1670 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5369 2.2660 -1.4886 N 0 0 0 0 0 0 0 0 0 0 0 0 0.8617 1.3603 -1.4781 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2640 4.2746 -0.0222 N 0 0 0 0 0 0 0 0 0 0 0 0 7.0668 16.0154 0.0216 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7410 18.7897 0.0253 H 0 0 0 0 0 0 0 0 0 0 0 0 14.9729 14.7855 -1.3869 H 0 0 0 0 0 0 0 0 0 0 0 0 15.6164 15.7462 0.6099 H 0 0 0 0 0 0 0 0 0 0 0 0 14.3676 13.8058 0.6128 H 0 0 0 0 0 0 0 0 0 0 0 0 11.7526 24.1832 -2.7400 H 0 0 0 0 0 0 0 0 0 0 0 0 11.8803 25.7534 0.0324 H 0 0 0 0 0 0 0 0 0 0 0 0 11.8353 24.1519 2.7896 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8100 10.2869 -0.0398 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3481 10.3979 1.1470 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3266 10.4110 -1.1603 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0964 7.7277 -1.1921 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1181 7.7146 1.1151 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9111 7.4952 1.1439 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8896 7.5082 -1.1634 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6595 4.8250 -1.1953 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6811 4.8119 1.1120 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8963 0.1239 -0.4956 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2102 1.6631 1.0816 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3727 1.8707 0.6214 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0344 2.2185 -1.6350 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5907 4.8775 -2.5924 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9046 6.4167 -1.0153 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7666 4.3221 0.1242 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4281 4.6700 -2.1323 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2826 1.4558 -0.1928 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 1.9529 -2.4284 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0596 0.0000 -1.8056 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 33 1 0 0 0 0 2 20 2 0 0 0 0 2 5 1 0 0 0 0 3 20 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 11 2 0 0 0 0 6 34 1 0 0 0 0 7 9 1 0 0 0 0 7 11 1 0 0 0 0 7 8 2 0 0 0 0 9 10 1 0 0 0 0 10 35 1 0 0 0 0 10 36 1 0 0 0 0 10 37 1 0 0 0 0 11 12 1 0 0 0 0 12 17 1 0 0 0 0 12 13 2 0 0 0 0 13 14 1 0 0 0 0 13 19 1 0 0 0 0 14 15 2 0 0 0 0 14 38 1 0 0 0 0 15 16 1 0 0 0 0 15 39 1 0 0 0 0 16 17 2 0 0 0 0 16 40 1 0 0 0 0 17 18 1 0 0 0 0 20 21 1 0 0 0 0 21 22 1 0 0 0 0 21 41 1 0 0 0 0 22 23 1 0 0 0 0 22 42 1 0 0 0 0 22 43 1 0 0 0 0 23 24 1 0 0 0 0 23 44 1 0 0 0 0 23 45 1 0 0 0 0 24 25 1 0 0 0 0 24 46 1 0 0 0 0 24 47 1 0 0 0 0 25 32 1 0 0 0 0 25 48 1 0 0 0 0 25 49 1 0 0 0 0 26 30 1 0 0 0 0 26 27 1 0 0 0 0 26 50 1 0 0 0 0 26 51 1 0 0 0 0 27 32 1 0 0 0 0 27 52 1 0 0 0 0 27 53 1 0 0 0 0 28 32 1 0 0 0 0 28 29 1 0 0 0 0 28 54 1 0 0 0 0 28 55 1 0 0 0 0 29 30 1 0 0 0 0 29 56 1 0 0 0 0 29 57 1 0 0 0 0 30 31 1 0 0 0 0 31 58 1 0 0 0 0 31 59 1 0 0 0 0 31 60 1 0 0 0 0 M END > (341) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 32 > (341) PDGFR-beta > (341) 890 > (341) -1 > (341) P > (341) PDGFR-P339 $$$$ 3-indoleacrylonitrile tyrphostin 5 csChFnd70/05150717532D 35 37 0 0 0 0 0 0 0 0999 V2000 1.3398 3.3860 -1.1733 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4324 1.9113 -1.4967 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7331 1.1555 -1.2650 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9480 1.8647 -0.7106 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8762 3.3532 -0.3780 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5588 4.1151 -0.6130 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2880 5.6823 0.3086 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8441 5.6440 -0.1575 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8857 4.3374 0.1769 N 0 0 3 0 0 0 0 0 0 0 0 0 1.8449 6.8274 -0.1910 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3551 8.2566 -0.0903 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9002 8.5424 -0.1080 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1259 8.7691 -0.1219 N 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 9.2462 -0.0641 O 0 0 0 0 0 0 0 0 0 0 0 0 1.3123 9.4764 0.0343 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8543 10.9837 0.2793 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1199 12.1756 -0.3468 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0989 11.2219 1.1427 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6029 12.6290 1.3706 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8768 13.8129 0.7440 C 0 0 0 0 0 0 0 0 0 0 0 0 1.6310 13.5835 -0.1139 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9222 14.7454 -0.7261 O 0 0 0 0 0 0 0 0 0 0 0 0 3.3780 15.1977 0.9719 O 0 0 0 0 0 0 0 0 0 0 0 0 0.3274 3.9737 -1.3586 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4883 1.3421 -1.9318 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7941 0.0000 -1.5213 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9553 1.2657 -0.5342 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8495 6.6432 0.7160 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8888 4.0934 0.4362 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6829 6.6189 -0.2953 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1552 11.9963 -1.0114 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6656 10.3030 1.6318 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5674 12.8112 2.0348 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2748 15.0057 -1.6926 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9658 15.6705 1.8280 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 6 1 0 0 0 0 1 24 1 0 0 0 0 2 3 1 0 0 0 0 2 25 1 0 0 0 0 3 4 2 0 0 0 0 3 26 1 0 0 0 0 4 5 1 0 0 0 0 4 27 1 0 0 0 0 5 9 1 0 0 0 0 5 6 2 0 0 0 0 6 8 1 0 0 0 0 7 9 1 0 0 0 0 7 8 2 0 0 0 0 7 28 1 0 0 0 0 8 10 1 0 0 0 0 9 29 1 0 0 0 0 10 11 2 0 0 0 0 10 30 1 0 0 0 0 11 15 1 0 0 0 0 11 12 1 0 0 0 0 12 13 3 0 0 0 0 14 15 2 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 18 1 0 0 0 0 17 21 1 0 0 0 0 17 31 1 0 0 0 0 18 19 2 0 0 0 0 18 32 1 0 0 0 0 19 20 1 0 0 0 0 19 33 1 0 0 0 0 20 21 2 0 0 0 0 20 23 1 0 0 0 0 21 22 1 0 0 0 0 22 34 1 0 0 0 0 23 35 1 0 0 0 0 M END > (360) Indole-Containing Inhibitor 5 > (360) PDGFR-beta > (360) 1000 > (360) -1 > (360) P > (360) PDGFR-P358 $$$$ Structure136 csChFnd70/05150717532D 45 47 0 0 0 0 0 0 0 0999 V2000 2.5954 9.5776 0.0119 N 0 0 0 0 0 0 0 0 0 0 0 0 2.6187 7.8678 0.0026 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0568 6.9716 -0.0154 N 0 0 0 0 0 0 0 0 0 0 0 0 5.5794 7.7712 -0.0257 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6016 9.5947 -0.0167 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0504 6.8927 -0.0435 N 0 0 0 0 0 0 0 0 0 0 0 0 8.5496 7.6779 -0.0530 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6707 9.4859 -0.0450 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0425 6.7048 -0.0697 N 0 0 3 0 0 0 0 0 0 0 0 0 9.9490 4.9762 -0.0776 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3991 4.0310 -0.0937 N 0 0 3 0 0 0 0 0 0 0 0 0 8.5565 4.2697 -0.0700 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0726 6.9958 0.0127 N 0 0 0 0 0 0 0 0 0 0 0 0 10.3757 10.3339 -0.0548 C 0 0 0 0 0 0 0 0 0 0 0 0 11.1940 10.7268 1.4898 C 0 0 0 0 0 0 0 0 0 0 0 0 12.7827 11.5165 1.4719 C 0 0 0 0 0 0 0 0 0 0 0 0 13.5618 11.9180 -0.0733 C 0 0 0 0 0 0 0 0 0 0 0 0 12.7571 11.5318 -1.6094 C 0 0 0 0 0 0 0 0 0 0 0 0 11.1716 10.7355 -1.6089 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0278 10.4790 0.0032 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1825 10.4627 -0.0284 C 0 0 0 0 0 0 0 0 0 0 0 0 11.2975 2.1520 -0.1024 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3243 1.5561 -1.7022 C 0 0 0 0 0 0 0 0 0 0 0 0 13.1120 1.3980 -0.1205 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3497 1.5400 1.5068 C 0 0 0 0 0 0 0 0 0 0 0 0 10.1640 10.2512 -3.5382 Cl 0 0 0 0 0 0 0 0 0 0 0 0 10.2174 10.2251 3.4306 Cl 0 0 0 0 0 0 0 0 0 0 0 0 11.1535 7.2685 -0.0757 H 0 0 0 0 0 0 0 0 0 0 0 0 12.5101 4.5947 -0.0998 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0600 5.7501 0.0066 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 7.6296 0.0259 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4176 11.8213 2.6670 H 0 0 0 0 0 0 0 0 0 0 0 0 14.8036 12.5362 -0.0805 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3720 11.8490 -2.8117 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9934 11.8657 0.0109 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2370 11.8489 -0.0218 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9994 1.9920 -2.8486 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2486 0.1581 -1.7085 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0315 2.0933 -1.6893 H 0 0 0 0 0 0 0 0 0 0 0 0 13.8053 1.8226 1.0193 H 0 0 0 0 0 0 0 0 0 0 0 0 13.0365 0.0000 -0.1269 H 0 0 0 0 0 0 0 0 0 0 0 0 13.7872 1.8340 -1.2668 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0571 2.0773 1.5197 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2741 0.1421 1.5003 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0430 1.9646 2.6465 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 20 2 0 0 0 0 2 3 2 0 0 0 0 2 13 1 0 0 0 0 3 4 1 0 0 0 0 4 6 2 0 0 0 0 4 5 1 0 0 0 0 5 20 1 0 0 0 0 5 21 2 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 7 9 1 0 0 0 0 8 14 1 0 0 0 0 8 21 1 0 0 0 0 9 10 1 0 0 0 0 9 28 1 0 0 0 0 10 11 1 0 0 0 0 10 12 2 0 0 0 0 11 22 1 0 0 0 0 11 29 1 0 0 0 0 13 30 1 0 0 0 0 13 31 1 0 0 0 0 14 15 2 0 0 0 0 14 19 1 0 0 0 0 15 16 1 0 0 0 0 15 27 1 0 0 0 0 16 17 2 0 0 0 0 16 32 1 0 0 0 0 17 18 1 0 0 0 0 17 33 1 0 0 0 0 18 19 2 0 0 0 0 18 34 1 0 0 0 0 19 26 1 0 0 0 0 20 35 1 0 0 0 0 21 36 1 0 0 0 0 22 23 1 0 0 0 0 22 24 1 0 0 0 0 22 25 1 0 0 0 0 23 37 1 0 0 0 0 23 38 1 0 0 0 0 23 39 1 0 0 0 0 24 40 1 0 0 0 0 24 41 1 0 0 0 0 24 42 1 0 0 0 0 25 43 1 0 0 0 0 25 44 1 0 0 0 0 25 45 1 0 0 0 0 M END > (381) 9240345-4b > (381) PDGFR-beta > (381) 1110 > (381) -1 > (381) P > (381) PDGFR-P379 $$$$ csChFnd70/05150717532D 44 47 0 0 0 0 0 0 0 0999 V2000 5.7137 8.3926 0.0167 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5988 6.6823 -0.0028 N 0 0 0 0 0 0 0 0 0 0 0 0 5.7351 6.7666 0.0014 N 0 0 0 0 0 0 0 0 0 0 0 0 7.2213 9.2403 0.0229 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6952 8.3167 0.0124 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2776 10.9812 0.0387 C 0 0 0 0 0 0 0 0 0 0 0 0 10.2848 10.7559 0.0329 C 0 0 0 0 0 0 0 0 0 0 0 0 11.6259 11.4307 0.0381 O 0 0 0 0 0 0 0 0 0 0 0 0 10.1942 9.0987 0.0174 N 0 0 3 0 0 0 0 0 0 0 0 0 8.7791 11.7510 0.0435 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8798 13.5740 0.0594 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9184 14.4496 -1.4202 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0115 16.1490 -1.3968 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0667 16.9831 0.0890 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0295 16.1224 1.5601 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9292 14.4233 1.5539 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8730 13.3459 3.4015 Cl 0 0 0 0 0 0 0 0 0 0 0 0 8.8500 13.4053 -3.2861 Cl 0 0 0 0 0 0 0 0 0 0 0 0 7.1472 5.9375 -0.0081 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0987 4.2354 -0.0248 N 0 0 3 0 0 0 0 0 0 0 0 0 5.5902 3.4152 0.1147 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3313 1.9465 -0.7259 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3492 4.0632 1.0999 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8606 3.2494 1.2354 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7121 8.1209 0.0064 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8397 1.1391 -0.5849 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6046 1.7910 0.3918 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9788 0.9062 0.5431 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5605 9.0571 0.0188 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1533 11.6935 0.0463 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0420 16.8283 -2.5410 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1396 18.3119 0.1006 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0734 16.7808 2.7159 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1115 3.6096 -0.1331 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2952 1.4370 -1.4891 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5485 5.2020 1.7593 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8936 3.7552 1.9974 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0867 7.8899 -1.2628 H 0 0 0 0 0 0 0 0 0 0 0 0 12.6834 8.7946 0.6444 H 0 0 0 0 0 0 0 0 0 0 0 0 11.4954 6.9506 0.6293 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6358 0.0000 -1.2425 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0314 0.0461 1.5735 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 1.8011 0.7563 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7290 0.2312 -0.5912 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 29 1 0 0 0 0 2 19 2 0 0 0 0 2 5 1 0 0 0 0 3 19 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 10 2 0 0 0 0 6 30 1 0 0 0 0 7 9 1 0 0 0 0 7 10 1 0 0 0 0 7 8 2 0 0 0 0 9 25 1 0 0 0 0 10 11 1 0 0 0 0 11 16 1 0 0 0 0 11 12 2 0 0 0 0 12 13 1 0 0 0 0 12 18 1 0 0 0 0 13 14 2 0 0 0 0 13 31 1 0 0 0 0 14 15 1 0 0 0 0 14 32 1 0 0 0 0 15 16 2 0 0 0 0 15 33 1 0 0 0 0 16 17 1 0 0 0 0 19 20 1 0 0 0 0 20 21 1 0 0 0 0 20 34 1 0 0 0 0 21 22 1 0 0 0 0 21 23 2 0 0 0 0 22 26 2 0 0 0 0 22 35 1 0 0 0 0 23 24 1 0 0 0 0 23 36 1 0 0 0 0 24 27 2 0 0 0 0 24 37 1 0 0 0 0 25 38 1 0 0 0 0 25 39 1 0 0 0 0 25 40 1 0 0 0 0 26 27 1 0 0 0 0 26 41 1 0 0 0 0 27 28 1 0 0 0 0 28 42 1 0 0 0 0 28 43 1 0 0 0 0 28 44 1 0 0 0 0 M END > (385) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 46 > (385) PDGFR-beta > (385) 1200 > (385) -1 > (385) P > (385) PDGFR-P383 $$$$ PD0173956 csChFnd70/05150717532D 41 44 0 0 0 0 0 0 0 0999 V2000 3.5539 14.4150 -0.7349 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1245 17.1532 -0.8061 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1345 15.3429 -0.6781 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9729 15.3239 -0.9278 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9812 17.1343 -1.0542 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5522 18.0467 -0.9900 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1091 14.2241 -0.4465 Cl 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 14.1812 -1.0092 Cl 0 0 0 0 0 0 0 0 0 0 0 0 3.4501 4.4855 1.3050 N 0 0 3 0 0 0 0 0 0 0 0 0 3.4795 3.6356 2.9355 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4352 3.5218 5.9364 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5389 1.9541 6.1602 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6186 1.2229 4.7710 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5872 2.0598 3.1608 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4074 4.3631 4.3284 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5548 12.4728 -0.5991 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4289 11.6752 1.0087 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6824 11.3889 -2.1842 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7887 12.0877 -3.6204 O 0 0 0 0 0 0 0 0 0 0 0 0 3.6834 9.6231 -2.0620 N 0 0 3 0 0 0 0 0 0 0 0 0 3.8196 8.5575 -3.6595 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4445 6.2992 1.2267 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5653 8.8122 -0.4559 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4334 9.8197 1.0964 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3075 8.9391 2.7111 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3180 7.2048 2.7140 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5657 7.0715 -0.3280 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5679 1.1333 7.7341 F 0 0 0 0 0 0 0 0 0 0 0 0 6.3469 17.8730 -0.7623 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7585 17.8393 -1.2039 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5515 19.4624 -1.0899 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4335 3.8009 0.2298 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1518 4.0901 7.0217 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9203 0.0000 4.9484 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8688 1.4892 2.0779 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1072 5.5855 4.1543 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3284 12.4520 2.1922 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5071 8.2798 -4.1615 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5674 9.2740 -4.6491 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4853 7.3259 -3.3568 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2046 9.6652 3.9263 H 0 0 0 0 0 0 0 0 0 0 0 0 1 16 1 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 2 3 1 0 0 0 0 2 6 2 0 0 0 0 2 29 1 0 0 0 0 3 7 1 0 0 0 0 4 5 2 0 0 0 0 4 8 1 0 0 0 0 5 6 1 0 0 0 0 5 30 1 0 0 0 0 6 31 1 0 0 0 0 9 22 1 0 0 0 0 9 10 1 0 0 0 0 9 32 1 0 0 0 0 10 14 2 0 0 0 0 10 15 1 0 0 0 0 11 12 1 0 0 0 0 11 15 2 0 0 0 0 11 33 1 0 0 0 0 12 13 2 0 0 0 0 12 28 1 0 0 0 0 13 14 1 0 0 0 0 13 34 1 0 0 0 0 14 35 1 0 0 0 0 15 36 1 0 0 0 0 16 18 1 0 0 0 0 16 17 2 0 0 0 0 17 24 1 0 0 0 0 17 37 1 0 0 0 0 18 20 1 0 0 0 0 18 19 2 0 0 0 0 20 23 1 0 0 0 0 20 21 1 0 0 0 0 21 38 1 0 0 0 0 21 39 1 0 0 0 0 21 40 1 0 0 0 0 22 26 2 0 0 0 0 22 27 1 0 0 0 0 23 27 2 0 0 0 0 23 24 1 0 0 0 0 24 25 2 0 0 0 0 25 26 1 0 0 0 0 25 41 1 0 0 0 0 M END > (399) PD173956 > (399) PDGFR-beta > (399) 1250 > (399) -1 > (399) P > (399) PDGFR-P397 $$$$ Structure111 csChFnd70/05150717532D 37 39 0 0 0 0 0 0 0 0999 V2000 1.3411 11.9347 0.0119 N 0 0 0 0 0 0 0 0 0 0 0 0 2.7890 12.8378 0.0029 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3223 12.1021 -0.0157 N 0 0 0 0 0 0 0 0 0 0 0 0 4.4679 10.4021 -0.0262 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9576 9.3987 -0.0171 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3641 10.2395 0.0026 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0514 9.6288 -0.0450 N 0 0 3 0 0 0 0 0 0 0 0 0 6.1916 7.9045 -0.0550 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6504 6.8260 -0.0453 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0648 7.5860 -0.0272 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8059 4.9292 -0.0565 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8642 4.0401 -1.6116 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0091 2.2719 -1.6130 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0964 1.3826 -0.0773 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0386 2.2562 1.4688 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9020 4.0249 1.4881 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6075 7.2388 -0.0715 O 0 0 0 0 0 0 0 0 0 0 0 0 4.7541 5.1537 -3.5404 Cl 0 0 0 0 0 0 0 0 0 0 0 0 7.6058 10.6895 -0.0548 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8303 5.1190 3.4297 Cl 0 0 0 0 0 0 0 0 0 0 0 0 2.6912 14.6084 0.0128 N 0 0 0 0 0 0 0 0 0 0 0 0 1.0123 15.4580 0.0327 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2665 15.6377 0.0032 C 0 0 0 0 0 0 0 0 0 0 0 0 0.1811 9.5150 0.0100 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9132 6.8126 -0.0200 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0540 1.5821 -2.8157 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2096 0.0000 -0.0854 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1064 1.5542 2.6634 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0038 10.9464 1.2628 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6292 10.0115 -0.7278 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3407 11.8999 -0.7066 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 14.4910 0.0374 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9047 16.2519 1.1811 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8832 16.2634 -1.1052 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6449 15.8996 -1.3190 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0381 16.8466 0.6715 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2886 14.9327 0.6502 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 2 3 1 0 0 0 0 2 21 1 0 0 0 0 3 4 2 0 0 0 0 4 7 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 5 6 2 0 0 0 0 6 24 1 0 0 0 0 7 8 1 0 0 0 0 7 19 1 0 0 0 0 8 9 1 0 0 0 0 8 17 2 0 0 0 0 9 11 1 0 0 0 0 9 10 2 0 0 0 0 10 25 1 0 0 0 0 11 12 2 0 0 0 0 11 16 1 0 0 0 0 12 13 1 0 0 0 0 12 18 1 0 0 0 0 13 14 2 0 0 0 0 13 26 1 0 0 0 0 14 15 1 0 0 0 0 14 27 1 0 0 0 0 15 16 2 0 0 0 0 15 28 1 0 0 0 0 16 20 1 0 0 0 0 19 29 1 0 0 0 0 19 30 1 0 0 0 0 19 31 1 0 0 0 0 21 22 1 0 0 0 0 21 23 1 0 0 0 0 22 32 1 0 0 0 0 22 33 1 0 0 0 0 22 34 1 0 0 0 0 23 35 1 0 0 0 0 23 36 1 0 0 0 0 23 37 1 0 0 0 0 M END > (408) 17964795-4 > (408) PDGFR-beta > (408) 1300 > (408) -1 > (408) P > (408) PDGFR-P406 $$$$ Structure140 csChFnd70/05150717532D 39 41 0 0 0 0 0 0 0 0999 V2000 2.3271 8.5873 0.0107 N 0 0 0 0 0 0 0 0 0 0 0 0 2.3479 7.0543 0.0023 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6373 6.2507 -0.0138 N 0 0 0 0 0 0 0 0 0 0 0 0 5.0025 6.9677 -0.0230 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0224 8.6026 -0.0150 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3214 6.1800 -0.0390 N 0 0 0 0 0 0 0 0 0 0 0 0 7.6656 6.8840 -0.0476 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7742 8.5051 -0.0403 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0041 6.0115 -0.0625 N 0 0 3 0 0 0 0 0 0 0 0 0 8.9202 4.4617 -0.0696 C 0 0 0 0 0 0 0 0 0 0 0 0 10.2204 3.6142 -0.0841 N 0 0 3 0 0 0 0 0 0 0 0 0 7.6718 3.8282 -0.0628 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9617 6.2725 0.0114 N 0 0 0 0 0 0 0 0 0 0 0 0 9.3028 9.2654 -0.0492 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0365 9.6176 1.3357 C 0 0 0 0 0 0 0 0 0 0 0 0 11.4609 10.3256 1.3197 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1595 10.6856 -0.0657 C 0 0 0 0 0 0 0 0 0 0 0 0 11.4380 10.3394 -1.4430 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0165 9.6255 -1.4425 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6113 9.3955 0.0029 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4398 9.3809 -0.0255 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1130 9.1912 -3.1723 Cl 0 0 0 0 0 0 0 0 0 0 0 0 9.1609 9.1678 3.0758 Cl 0 0 0 0 0 0 0 0 0 0 0 0 11.7562 1.2534 -0.1080 C 0 0 0 0 0 0 0 0 0 0 0 0 10.1293 1.9295 -0.0918 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0002 6.5169 -0.0678 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2165 4.1196 -0.0895 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9504 5.1555 0.0059 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 6.8407 0.0233 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0302 10.5989 2.3912 H 0 0 0 0 0 0 0 0 0 0 0 0 13.2729 11.2399 -0.0722 H 0 0 0 0 0 0 0 0 0 0 0 0 11.9893 10.6238 -2.5210 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5805 10.6388 0.0098 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4887 10.6237 -0.0196 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3616 1.6444 -1.1358 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3778 1.6341 0.9139 H 0 0 0 0 0 0 0 0 0 0 0 0 11.6885 0.0000 -0.1138 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5239 1.5387 0.9360 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5077 1.5488 -1.1137 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 20 2 0 0 0 0 2 3 2 0 0 0 0 2 13 1 0 0 0 0 3 4 1 0 0 0 0 4 6 2 0 0 0 0 4 5 1 0 0 0 0 5 20 1 0 0 0 0 5 21 2 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 7 9 1 0 0 0 0 8 14 1 0 0 0 0 8 21 1 0 0 0 0 9 10 1 0 0 0 0 9 26 1 0 0 0 0 10 11 1 0 0 0 0 10 12 2 0 0 0 0 11 25 1 0 0 0 0 11 27 1 0 0 0 0 13 28 1 0 0 0 0 13 29 1 0 0 0 0 14 15 2 0 0 0 0 14 19 1 0 0 0 0 15 16 1 0 0 0 0 15 23 1 0 0 0 0 16 17 2 0 0 0 0 16 30 1 0 0 0 0 17 18 1 0 0 0 0 17 31 1 0 0 0 0 18 19 2 0 0 0 0 18 32 1 0 0 0 0 19 22 1 0 0 0 0 20 33 1 0 0 0 0 21 34 1 0 0 0 0 24 25 1 0 0 0 0 24 35 1 0 0 0 0 24 36 1 0 0 0 0 24 37 1 0 0 0 0 25 38 1 0 0 0 0 25 39 1 0 0 0 0 M END > (413) 9240345-4f > (413) PDGFR-beta > (413) 1300 > (413) -1 > (413) P > (413) PDGFR-P411 $$$$ PD0180970 csChFnd70/05150717532D 44 47 0 0 0 0 0 0 0 0999 V2000 3.5238 14.9984 0.7708 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0555 17.7099 1.1021 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0832 15.9157 0.9579 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9464 15.9022 0.7235 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9370 17.6964 0.8689 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4867 18.5973 1.0611 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0532 14.8042 1.0105 Cl 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 14.7741 0.4817 Cl 0 0 0 0 0 0 0 0 0 0 0 0 3.5438 13.0737 0.6149 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4355 12.0513 2.0733 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6716 12.2479 -1.1012 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7625 13.1479 -2.4060 O 0 0 0 0 0 0 0 0 0 0 0 0 3.6898 10.4983 -1.2439 N 0 0 3 0 0 0 0 0 0 0 0 0 3.8265 9.6925 -2.9694 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5319 4.9575 1.2943 N 0 0 3 0 0 0 0 0 0 0 0 0 3.5731 3.8819 2.7665 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7032 2.2943 2.7538 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7460 1.2345 4.2078 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6551 1.7539 5.6783 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5226 3.3361 5.6941 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4899 4.3966 4.2395 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5096 3.8983 7.2964 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6949 0.7153 7.0997 F 0 0 0 0 0 0 0 0 0 0 0 0 3.4576 10.2189 1.8831 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5893 9.4633 0.2109 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3512 9.1136 3.3364 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5094 6.7476 1.4876 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6067 7.7372 0.0773 N 0 0 0 0 0 0 0 0 0 0 0 0 3.3789 7.4131 3.0812 N 0 0 0 0 0 0 0 0 0 0 0 0 6.2613 18.4214 1.2476 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7170 18.3976 0.8320 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4722 20.0004 1.1743 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3350 12.6358 3.3498 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5249 9.4811 -3.4978 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5560 10.5497 -3.8361 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5005 8.4467 -2.8582 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5192 4.4464 0.1381 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9933 1.8892 1.6077 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0698 0.0000 4.1986 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1719 5.6279 4.2501 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8497 3.4341 7.2143 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5040 5.3162 7.3828 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8888 3.3510 8.4512 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2492 9.6437 4.6365 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 2 3 1 0 0 0 0 2 6 2 0 0 0 0 2 30 1 0 0 0 0 3 7 1 0 0 0 0 4 5 2 0 0 0 0 4 8 1 0 0 0 0 5 6 1 0 0 0 0 5 31 1 0 0 0 0 6 32 1 0 0 0 0 9 11 1 0 0 0 0 9 10 2 0 0 0 0 10 24 1 0 0 0 0 10 33 1 0 0 0 0 11 13 1 0 0 0 0 11 12 2 0 0 0 0 13 25 1 0 0 0 0 13 14 1 0 0 0 0 14 34 1 0 0 0 0 14 35 1 0 0 0 0 14 36 1 0 0 0 0 15 16 1 0 0 0 0 15 27 1 0 0 0 0 15 37 1 0 0 0 0 16 17 1 0 0 0 0 16 21 2 0 0 0 0 17 18 2 0 0 0 0 17 38 1 0 0 0 0 18 19 1 0 0 0 0 18 39 1 0 0 0 0 19 20 2 0 0 0 0 19 23 1 0 0 0 0 20 21 1 0 0 0 0 20 22 1 0 0 0 0 21 40 1 0 0 0 0 22 41 1 0 0 0 0 22 42 1 0 0 0 0 22 43 1 0 0 0 0 24 26 1 0 0 0 0 24 25 2 0 0 0 0 25 28 1 0 0 0 0 26 29 2 0 0 0 0 26 44 1 0 0 0 0 27 29 1 0 0 0 0 27 28 2 0 0 0 0 M END > (426) PD180970 > (426) PDGFR-beta > (426) 1430 > (426) -1 > (426) P > (426) PDGFR-P424 $$$$ csChFnd70/05150717532D 48 51 0 0 0 0 0 0 0 0999 V2000 5.9769 9.7712 0.0166 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8584 8.0633 -0.0029 N 0 0 0 0 0 0 0 0 0 0 0 0 5.9983 8.1474 0.0012 N 0 0 0 0 0 0 0 0 0 0 0 0 7.4824 10.6177 0.0228 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9544 9.6954 0.0123 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5387 12.3564 0.0384 C 0 0 0 0 0 0 0 0 0 0 0 0 10.5419 12.1315 0.0321 C 0 0 0 0 0 0 0 0 0 0 0 0 11.8811 12.8055 0.0364 O 0 0 0 0 0 0 0 0 0 0 0 0 10.4516 10.4764 0.0172 N 0 0 3 0 0 0 0 0 0 0 0 0 9.0382 13.1251 0.0433 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1385 14.9457 0.0591 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1770 15.8202 -1.4186 C 0 0 0 0 0 0 0 0 0 0 0 0 9.2701 17.5174 -1.3953 C 0 0 0 0 0 0 0 0 0 0 0 0 9.3251 18.3502 0.0885 C 0 0 0 0 0 0 0 0 0 0 0 0 9.2874 17.4908 1.5576 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1879 15.7938 1.5516 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1316 14.7181 3.3967 Cl 0 0 0 0 0 0 0 0 0 0 0 0 9.1088 14.7771 -3.2820 Cl 0 0 0 0 0 0 0 0 0 0 0 0 7.4086 7.3193 -0.0082 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3603 5.6199 -0.0241 N 0 0 3 0 0 0 0 0 0 0 0 0 5.8513 4.7995 0.1159 C 0 0 0 0 0 0 0 0 0 0 0 0 11.9674 9.5001 0.0069 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1060 2.5245 -0.5847 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5943 3.3328 -0.7234 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6137 5.4480 1.0997 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1256 4.6381 1.2371 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7795 5.3457 2.2988 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8674 3.1770 0.3928 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4018 2.3805 0.5285 O 0 0 0 0 0 0 0 0 0 0 0 0 1.2231 0.8789 -0.3693 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8252 10.4347 0.0187 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4159 13.0676 0.0460 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3003 18.1955 -2.5379 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3983 19.6773 0.1000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3311 18.1484 2.7119 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3718 4.9951 -0.1323 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3417 9.2689 -1.2604 H 0 0 0 0 0 0 0 0 0 0 0 0 12.9372 10.1732 0.6440 H 0 0 0 0 0 0 0 0 0 0 0 0 11.7509 8.3316 0.6294 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9038 1.3870 -1.2421 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5581 2.8249 -1.4849 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8148 6.5855 1.7575 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8947 4.8656 3.5461 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8851 6.6828 2.3228 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5849 5.0005 1.7954 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3827 1.1195 -1.6795 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1502 0.0000 0.0401 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 0.3717 -0.1536 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 31 1 0 0 0 0 2 19 2 0 0 0 0 2 5 1 0 0 0 0 3 19 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 10 2 0 0 0 0 6 32 1 0 0 0 0 7 9 1 0 0 0 0 7 10 1 0 0 0 0 7 8 2 0 0 0 0 9 22 1 0 0 0 0 10 11 1 0 0 0 0 11 16 1 0 0 0 0 11 12 2 0 0 0 0 12 13 1 0 0 0 0 12 18 1 0 0 0 0 13 14 2 0 0 0 0 13 33 1 0 0 0 0 14 15 1 0 0 0 0 14 34 1 0 0 0 0 15 16 2 0 0 0 0 15 35 1 0 0 0 0 16 17 1 0 0 0 0 19 20 1 0 0 0 0 20 21 1 0 0 0 0 20 36 1 0 0 0 0 21 24 1 0 0 0 0 21 25 2 0 0 0 0 22 37 1 0 0 0 0 22 38 1 0 0 0 0 22 39 1 0 0 0 0 23 28 1 0 0 0 0 23 24 2 0 0 0 0 23 40 1 0 0 0 0 24 41 1 0 0 0 0 25 26 1 0 0 0 0 25 42 1 0 0 0 0 26 28 2 0 0 0 0 26 27 1 0 0 0 0 27 43 1 0 0 0 0 27 44 1 0 0 0 0 27 45 1 0 0 0 0 28 29 1 0 0 0 0 29 30 1 0 0 0 0 30 46 1 0 0 0 0 30 47 1 0 0 0 0 30 48 1 0 0 0 0 M END > (431) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 53 > (431) PDGFR-beta > (431) 1500 > (431) -1 > (431) P > (431) PDGFR-P429 $$$$ 3-substituted indolin-2-one 16d csChFnd70/05150717532D 46 48 0 0 0 0 0 0 0 0999 V2000 3.6120 4.2541 -0.1497 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0238 2.8097 -1.7564 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0714 4.4113 -1.5238 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8513 5.1318 -0.7128 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2316 6.8115 -0.6563 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7227 6.9581 -1.4807 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1546 5.5318 -1.9582 N 0 0 3 0 0 0 0 0 0 0 0 0 7.4419 8.1622 -1.6949 O 0 0 0 0 0 0 0 0 0 0 0 0 4.3698 7.9878 0.0245 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9931 9.5030 0.1363 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1648 10.8860 0.0469 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5368 9.8813 0.3615 N 0 0 3 0 0 0 0 0 0 0 0 0 2.4336 11.0520 -0.1877 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6688 11.4552 0.4054 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5856 2.6650 -0.3922 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7887 1.9491 -1.1924 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1632 12.3470 0.6319 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2375 12.0960 0.2160 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8697 13.8118 0.1951 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5154 14.3636 1.8519 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1475 16.0794 1.8308 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1667 16.7883 0.6155 O 0 0 0 0 0 0 0 0 0 0 0 0 3.7986 16.8203 3.1623 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5854 0.0000 0.4817 O 0 0 0 0 0 0 0 0 0 0 0 0 1.3601 2.4059 1.5690 O 0 0 0 0 0 0 0 0 0 0 0 0 2.0190 1.5462 0.3179 S 0 0 0 0 0 0 0 0 0 0 0 0 0.6809 1.4919 -1.0697 N 0 0 0 0 0 0 0 0 0 0 0 0 2.6768 4.8126 0.4791 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9549 2.2380 -2.3794 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1023 5.3124 -2.5325 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2190 7.7467 0.4708 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3866 9.1452 0.4709 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8534 11.0706 0.9411 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1922 12.1343 -0.8055 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0029 10.0711 -0.8686 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7604 0.7054 -1.3773 H 0 0 0 0 0 0 0 0 0 0 0 0 8.6920 12.5804 -0.4982 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9159 13.4452 1.2183 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9627 11.6602 1.3393 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8662 14.4527 -0.2604 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8593 14.0189 -0.5449 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5189 13.7228 2.3072 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5258 14.1564 2.5918 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5710 17.9208 3.0905 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 0.5954 -1.1630 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5782 2.3565 -1.7894 H 0 0 0 0 0 0 0 0 0 0 0 0 1 15 1 0 0 0 0 1 4 2 0 0 0 0 1 28 1 0 0 0 0 2 16 1 0 0 0 0 2 3 2 0 0 0 0 2 29 1 0 0 0 0 3 7 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 5 9 2 0 0 0 0 6 7 1 0 0 0 0 6 8 2 0 0 0 0 7 30 1 0 0 0 0 9 10 1 0 0 0 0 9 31 1 0 0 0 0 10 11 2 0 0 0 0 10 12 1 0 0 0 0 11 18 1 0 0 0 0 11 13 1 0 0 0 0 12 14 1 0 0 0 0 12 32 1 0 0 0 0 13 33 1 0 0 0 0 13 34 1 0 0 0 0 13 35 1 0 0 0 0 14 18 2 0 0 0 0 14 17 1 0 0 0 0 15 16 2 0 0 0 0 15 26 1 0 0 0 0 16 36 1 0 0 0 0 17 37 1 0 0 0 0 17 38 1 0 0 0 0 17 39 1 0 0 0 0 18 19 1 0 0 0 0 19 20 1 0 0 0 0 19 40 1 0 0 0 0 19 41 1 0 0 0 0 20 21 1 0 0 0 0 20 42 1 0 0 0 0 20 43 1 0 0 0 0 21 23 1 0 0 0 0 21 22 2 0 0 0 0 23 44 1 0 0 0 0 24 26 2 0 0 0 0 25 26 2 0 0 0 0 26 27 1 0 0 0 0 27 45 1 0 0 0 0 27 46 1 0 0 0 0 M END > (439) 3-substituted indolin-2-one 16d > (439) PDGFR-beta > (439) 1530 > (439) -1 > (439) P > (439) PDGFR-P437 $$$$ csChFnd70/05150717532D 49 52 0 0 0 0 0 0 0 0999 V2000 6.4416 10.5826 0.0155 C 0 0 0 0 0 0 0 0 0 0 0 0 9.3247 8.8735 -0.0033 N 0 0 0 0 0 0 0 0 0 0 0 0 6.4629 8.9577 0.0006 N 0 0 0 0 0 0 0 0 0 0 0 0 7.9480 11.4296 0.0217 C 0 0 0 0 0 0 0 0 0 0 0 0 9.4209 10.5067 0.0116 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0043 13.1695 0.0369 C 0 0 0 0 0 0 0 0 0 0 0 0 11.0094 12.9444 0.0337 C 0 0 0 0 0 0 0 0 0 0 0 0 12.3496 13.6186 0.0399 O 0 0 0 0 0 0 0 0 0 0 0 0 10.9189 11.2881 0.0176 N 0 0 3 0 0 0 0 0 0 0 0 0 9.5048 13.9388 0.0417 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6052 15.7604 0.0573 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6439 16.6352 -1.4214 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7378 18.3333 -1.3984 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7933 19.1671 0.0862 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7554 18.3073 1.5564 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6545 16.6093 1.5506 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5975 15.5332 3.3970 Cl 0 0 0 0 0 0 0 0 0 0 0 0 9.5751 15.5912 -3.2858 Cl 0 0 0 0 0 0 0 0 0 0 0 0 7.8741 8.1292 -0.0086 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8257 6.4282 -0.0241 N 0 0 3 0 0 0 0 0 0 0 0 0 6.3183 5.6086 0.1158 C 0 0 0 0 0 0 0 0 0 0 0 0 12.4357 10.3112 0.0069 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0611 4.1415 -0.7239 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0799 6.2576 1.1002 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5855 5.4437 1.2388 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3272 3.9815 0.3944 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3712 6.0816 2.1978 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8612 5.1814 2.2791 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5659 3.3291 -0.5840 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3116 1.8967 -1.4112 O 0 0 0 0 0 0 0 0 0 0 0 0 2.7396 1.1298 -1.2163 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2891 11.2466 0.0175 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8808 13.8812 0.0443 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7682 19.0119 -2.5420 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8671 20.4950 0.0974 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7991 18.9656 2.7113 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8378 5.8029 -0.1321 H 0 0 0 0 0 0 0 0 0 0 0 0 12.8107 10.0809 -1.2612 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4060 10.9842 0.6452 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2189 9.1415 0.6288 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0253 3.6335 -1.4862 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2809 7.3959 1.7581 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1629 3.3479 0.5033 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 5.8238 3.0837 H 0 0 0 0 0 0 0 0 0 0 0 0 0.3337 5.0803 1.0489 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0981 3.9533 2.7666 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7000 0.0000 -1.9403 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5415 0.8384 0.0791 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7783 1.9660 -1.6389 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 32 1 0 0 0 0 2 19 2 0 0 0 0 2 5 1 0 0 0 0 3 19 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 10 2 0 0 0 0 6 33 1 0 0 0 0 7 9 1 0 0 0 0 7 10 1 0 0 0 0 7 8 2 0 0 0 0 9 22 1 0 0 0 0 10 11 1 0 0 0 0 11 16 1 0 0 0 0 11 12 2 0 0 0 0 12 13 1 0 0 0 0 12 18 1 0 0 0 0 13 14 2 0 0 0 0 13 34 1 0 0 0 0 14 15 1 0 0 0 0 14 35 1 0 0 0 0 15 16 2 0 0 0 0 15 36 1 0 0 0 0 16 17 1 0 0 0 0 19 20 1 0 0 0 0 20 21 1 0 0 0 0 20 37 1 0 0 0 0 21 23 1 0 0 0 0 21 24 2 0 0 0 0 22 38 1 0 0 0 0 22 39 1 0 0 0 0 22 40 1 0 0 0 0 23 29 2 0 0 0 0 23 41 1 0 0 0 0 24 25 1 0 0 0 0 24 42 1 0 0 0 0 25 26 2 0 0 0 0 25 27 1 0 0 0 0 26 29 1 0 0 0 0 26 43 1 0 0 0 0 27 28 1 0 0 0 0 28 44 1 0 0 0 0 28 45 1 0 0 0 0 28 46 1 0 0 0 0 29 30 1 0 0 0 0 30 31 1 0 0 0 0 31 47 1 0 0 0 0 31 48 1 0 0 0 0 31 49 1 0 0 0 0 M END > (448) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 54 > (448) PDGFR-beta > (448) 1700 > (448) -1 > (448) P > (448) PDGFR-P446 $$$$ csChFnd70/05150717532D 45 48 0 0 0 0 0 0 0 0999 V2000 3.7591 8.5419 0.1916 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2347 7.0485 -0.2863 N 0 0 0 0 0 0 0 0 0 0 0 0 3.7795 7.1213 0.1962 N 0 0 0 0 0 0 0 0 0 0 0 0 5.0504 9.2828 -0.0669 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3151 8.4764 -0.3107 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0963 10.8040 -0.0856 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6746 10.6081 -0.5915 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8233 11.1981 -0.8210 O 0 0 0 0 0 0 0 0 0 0 0 0 7.5991 9.1601 -0.5678 N 0 0 3 0 0 0 0 0 0 0 0 0 6.3824 11.4769 -0.3430 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4661 13.0697 -0.3697 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2486 13.8153 -1.6559 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3276 15.3002 -1.6732 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6217 16.0482 -0.4193 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8384 15.3157 0.8592 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7567 13.8312 0.8925 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0215 12.9143 2.4997 Cl 0 0 0 0 0 0 0 0 0 0 0 0 5.8801 12.8785 -3.2307 Cl 0 0 0 0 0 0 0 0 0 0 0 0 4.9912 6.3972 -0.0378 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9518 4.9106 -0.0216 N 0 0 3 0 0 0 0 0 0 0 0 0 3.6316 4.1927 0.1004 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2743 2.0885 0.7569 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9016 8.3064 -0.8188 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0672 4.1596 -0.1994 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0195 2.7730 0.3406 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3687 4.8705 -0.3204 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5834 2.7935 0.6391 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8183 2.1214 1.0477 O 0 0 0 0 0 0 0 0 0 0 0 0 4.6866 0.6876 1.5899 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7687 9.1220 0.3780 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1315 11.4259 0.1000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1599 15.8785 -2.6679 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6827 17.2093 -0.4387 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0680 15.9060 1.8344 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8387 4.3640 -0.0947 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2332 1.0055 1.1787 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0108 8.0877 -1.9667 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8393 8.9038 -0.4435 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8235 7.2923 -0.2332 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0843 4.6900 -0.5233 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 2.2214 0.4329 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4028 5.9537 -0.7423 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7489 0.2783 1.8757 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9997 0.6906 2.5414 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2112 0.0000 0.7663 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 30 1 0 0 0 0 2 19 2 0 0 0 0 2 5 1 0 0 0 0 3 19 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 10 2 0 0 0 0 6 31 1 0 0 0 0 7 9 1 0 0 0 0 7 10 1 0 0 0 0 7 8 2 0 0 0 0 9 23 1 0 0 0 0 10 11 1 0 0 0 0 11 16 1 0 0 0 0 11 12 2 0 0 0 0 12 13 1 0 0 0 0 12 18 1 0 0 0 0 13 14 2 0 0 0 0 13 32 1 0 0 0 0 14 15 1 0 0 0 0 14 33 1 0 0 0 0 15 16 2 0 0 0 0 15 34 1 0 0 0 0 16 17 1 0 0 0 0 19 20 1 0 0 0 0 20 21 1 0 0 0 0 20 35 1 0 0 0 0 21 26 1 0 0 0 0 21 27 2 0 0 0 0 22 25 2 0 0 0 0 22 27 1 0 0 0 0 22 36 1 0 0 0 0 23 37 1 0 0 0 0 23 38 1 0 0 0 0 23 39 1 0 0 0 0 24 25 1 0 0 0 0 24 26 2 0 0 0 0 24 40 1 0 0 0 0 25 41 1 0 0 0 0 26 42 1 0 0 0 0 27 28 1 0 0 0 0 28 29 1 0 0 0 0 29 43 1 0 0 0 0 29 44 1 0 0 0 0 29 45 1 0 0 0 0 M END > (455) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 47 > (455) PDGFR-beta > (455) 1800 > (455) -1 > (455) P > (455) PDGFR-P453 $$$$ Structure113 csChFnd70/05150717532D 54 56 0 0 0 0 0 0 0 0999 V2000 3.7555 12.4602 -0.3380 N 0 0 0 0 0 0 0 0 0 0 0 0 5.3273 13.1656 -0.3900 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7571 12.2208 -0.5080 N 0 0 0 0 0 0 0 0 0 0 0 0 6.6670 10.5013 -0.5800 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0190 9.7042 -0.5282 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5434 10.7621 -0.4024 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1418 9.5123 -0.7020 N 0 0 3 0 0 0 0 0 0 0 0 0 8.0428 7.7692 -0.7740 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3535 6.9010 -0.7224 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8746 7.8772 -0.6013 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2458 4.9835 -0.8016 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1115 4.1457 -2.4009 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0116 2.3578 -2.4659 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0444 1.3978 -0.9501 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1768 2.2202 0.6396 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2857 4.0068 0.7221 C 0 0 0 0 0 0 0 0 0 0 0 0 9.3651 6.9103 -0.8821 O 0 0 0 0 0 0 0 0 0 0 0 0 6.0695 5.3484 -4.3048 Cl 0 0 0 0 0 0 0 0 0 0 0 0 9.8417 10.3608 -0.7551 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4525 5.0363 2.7184 Cl 0 0 0 0 0 0 0 0 0 0 0 0 5.4750 14.9492 -0.3188 N 0 0 3 0 0 0 0 0 0 0 0 0 3.9155 16.0275 -0.1884 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4375 17.9418 -0.1312 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8088 19.0681 0.0049 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3100 20.9060 0.0598 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1953 22.0551 -2.0143 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7853 22.0354 -0.1191 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2022 23.0455 1.4514 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2715 21.3043 1.6565 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2611 10.1991 -0.3595 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6169 7.2610 -0.5616 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9072 1.7080 -3.7028 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9659 0.0000 -1.0078 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2008 1.4632 1.8184 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3340 10.5127 0.5619 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7408 9.5685 -1.5060 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7151 11.6323 -1.3607 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6116 15.4882 -0.3551 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0883 15.7979 -1.3122 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2104 15.6958 0.9917 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2647 18.1715 0.9925 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1428 18.2736 -1.3112 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9816 18.8384 -1.1189 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1036 18.7363 1.1850 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1994 22.6474 -2.8145 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9658 20.7296 -2.4502 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 22.8023 -2.1281 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7382 21.5462 0.6956 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1217 23.3486 0.2835 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0127 23.0132 0.2929 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2456 24.0798 1.3288 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0115 23.2840 2.5863 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3702 21.3769 2.7438 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2229 20.2870 1.8999 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 2 3 1 0 0 0 0 2 21 1 0 0 0 0 3 4 2 0 0 0 0 4 7 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 5 6 2 0 0 0 0 6 30 1 0 0 0 0 7 8 1 0 0 0 0 7 19 1 0 0 0 0 8 9 1 0 0 0 0 8 17 2 0 0 0 0 9 11 1 0 0 0 0 9 10 2 0 0 0 0 10 31 1 0 0 0 0 11 12 2 0 0 0 0 11 16 1 0 0 0 0 12 13 1 0 0 0 0 12 18 1 0 0 0 0 13 14 2 0 0 0 0 13 32 1 0 0 0 0 14 15 1 0 0 0 0 14 33 1 0 0 0 0 15 16 2 0 0 0 0 15 34 1 0 0 0 0 16 20 1 0 0 0 0 19 35 1 0 0 0 0 19 36 1 0 0 0 0 19 37 1 0 0 0 0 21 22 1 0 0 0 0 21 38 1 0 0 0 0 22 23 1 0 0 0 0 22 39 1 0 0 0 0 22 40 1 0 0 0 0 23 24 1 0 0 0 0 23 41 1 0 0 0 0 23 42 1 0 0 0 0 24 25 1 0 0 0 0 24 43 1 0 0 0 0 24 44 1 0 0 0 0 25 27 1 0 0 0 0 25 29 1 0 0 0 0 26 27 1 0 0 0 0 26 45 1 0 0 0 0 26 46 1 0 0 0 0 26 47 1 0 0 0 0 27 48 1 0 0 0 0 27 49 1 0 0 0 0 28 29 1 0 0 0 0 28 50 1 0 0 0 0 28 51 1 0 0 0 0 28 52 1 0 0 0 0 29 53 1 0 0 0 0 29 54 1 0 0 0 0 M END > (471) 17964795-6 > (471) PDGFR-beta > (471) 2050 > (471) -1 > (471) P > (471) PDGFR-P469 $$$$ Structure108 csChFnd70/05150717532D 31 33 0 0 0 0 0 0 0 0999 V2000 1.0380 10.6793 0.0107 N 0 0 0 0 0 0 0 0 0 0 0 0 2.3335 11.4874 0.0026 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7055 10.8290 -0.0145 N 0 0 0 0 0 0 0 0 0 0 0 0 3.8359 9.3078 -0.0240 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4844 8.4100 -0.0153 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0586 9.1623 0.0023 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2528 8.6160 -0.0413 N 0 0 3 0 0 0 0 0 0 0 0 0 5.3782 7.0730 -0.0507 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9992 6.1079 -0.0416 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5803 6.7880 -0.0255 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1383 4.4107 -0.0515 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1900 3.6150 -1.4430 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3203 2.0329 -1.4442 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3988 1.2372 -0.0700 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3481 2.0191 1.3135 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2247 3.6016 1.3306 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6451 6.4773 -0.0655 O 0 0 0 0 0 0 0 0 0 0 0 0 2.2461 13.0717 0.0119 N 0 0 0 0 0 0 0 0 0 0 0 0 4.0902 4.6112 -3.1689 Cl 0 0 0 0 0 0 0 0 0 0 0 0 6.6436 9.5651 -0.0500 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1619 4.5809 3.0680 Cl 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 8.5141 0.0093 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5499 6.0960 -0.0190 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3604 1.4155 -2.5203 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4999 0.0000 -0.0771 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4096 1.3911 2.3824 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2514 13.5751 0.0243 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1795 13.6815 0.0063 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0001 9.7946 1.1289 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5593 8.9586 -0.6526 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4063 10.6483 -0.6328 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 2 3 1 0 0 0 0 2 18 1 0 0 0 0 3 4 2 0 0 0 0 4 7 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 5 6 2 0 0 0 0 6 22 1 0 0 0 0 7 8 1 0 0 0 0 7 20 1 0 0 0 0 8 9 1 0 0 0 0 8 17 2 0 0 0 0 9 11 1 0 0 0 0 9 10 2 0 0 0 0 10 23 1 0 0 0 0 11 12 2 0 0 0 0 11 16 1 0 0 0 0 12 13 1 0 0 0 0 12 19 1 0 0 0 0 13 14 2 0 0 0 0 13 24 1 0 0 0 0 14 15 1 0 0 0 0 14 25 1 0 0 0 0 15 16 2 0 0 0 0 15 26 1 0 0 0 0 16 21 1 0 0 0 0 18 27 1 0 0 0 0 18 28 1 0 0 0 0 20 29 1 0 0 0 0 20 30 1 0 0 0 0 20 31 1 0 0 0 0 M END > (493) 17964795-1 > (493) PDGFR-beta > (493) 2310 > (493) -1 > (493) P > (493) PDGFR-P491 $$$$ csChFnd70/05150717532D 57 60 0 0 0 0 0 0 0 0999 V2000 3.9367 15.9988 0.0120 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9720 14.2010 -0.0266 N 0 0 0 0 0 0 0 0 0 0 0 0 3.9598 14.2881 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 5.5218 16.8911 0.0017 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0726 15.9203 -0.0183 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5803 18.7227 0.0104 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7436 18.4871 -0.0216 C 0 0 0 0 0 0 0 0 0 0 0 0 10.1539 19.1975 -0.0319 O 0 0 0 0 0 0 0 0 0 0 0 0 8.6490 16.7436 -0.0296 N 0 0 3 0 0 0 0 0 0 0 0 0 10.2459 15.7159 -0.0497 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1593 19.5330 -0.0009 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2643 21.4509 0.0083 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2909 22.3667 -1.5515 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3883 24.1544 -1.5337 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4600 25.0370 0.0257 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4347 24.1369 1.5764 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3295 22.3495 1.5769 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2884 21.2227 3.5247 Cl 0 0 0 0 0 0 0 0 0 0 0 0 7.2024 21.2615 -3.5098 Cl 0 0 0 0 0 0 0 0 0 0 0 0 5.4455 13.4167 -0.0162 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3954 11.6276 -0.0259 N 0 0 3 0 0 0 0 0 0 0 0 0 3.7248 10.7244 -0.0156 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0326 8.7650 -0.0296 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2879 7.8217 -0.0187 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2597 3.4995 1.1098 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9619 4.9924 0.2865 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5834 5.9405 -0.0321 N 0 0 0 0 0 0 0 0 0 0 0 0 3.9173 5.4496 1.2363 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3044 3.0422 0.1600 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6384 2.5515 1.4285 N 0 0 0 0 0 0 0 0 0 0 0 0 2.9338 0.6702 1.4150 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7233 16.6971 0.0216 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3974 19.4714 0.0253 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6292 15.4672 -1.3868 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2728 16.4280 0.6099 H 0 0 0 0 0 0 0 0 0 0 0 0 10.0240 14.4876 0.6128 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4090 24.8648 -2.7400 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5366 26.4350 0.0324 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4917 24.8336 2.7895 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4664 10.9688 -0.0398 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0046 11.0797 1.1470 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9831 11.0928 -1.1602 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7528 8.4096 -1.1921 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7745 8.3965 1.1151 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5676 8.1771 1.1439 H 0 0 0 0 0 0 0 0 0 0 0 0 1.5460 8.1901 -1.1633 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7418 3.1883 -0.1815 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2216 3.1262 2.0752 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4798 5.3035 1.5778 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 5.3658 -0.6789 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4688 5.7661 2.5384 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1101 6.1564 0.9634 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1116 2.3354 0.4328 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7528 2.7257 -1.1421 H 0 0 0 0 0 0 0 0 0 0 0 0 3.8622 0.3320 2.4250 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7129 0.0000 1.6539 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4452 0.2827 0.1561 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 32 1 0 0 0 0 2 20 2 0 0 0 0 2 5 1 0 0 0 0 3 20 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 11 2 0 0 0 0 6 33 1 0 0 0 0 7 9 1 0 0 0 0 7 11 1 0 0 0 0 7 8 2 0 0 0 0 9 10 1 0 0 0 0 10 34 1 0 0 0 0 10 35 1 0 0 0 0 10 36 1 0 0 0 0 11 12 1 0 0 0 0 12 17 1 0 0 0 0 12 13 2 0 0 0 0 13 14 1 0 0 0 0 13 19 1 0 0 0 0 14 15 2 0 0 0 0 14 37 1 0 0 0 0 15 16 1 0 0 0 0 15 38 1 0 0 0 0 16 17 2 0 0 0 0 16 39 1 0 0 0 0 17 18 1 0 0 0 0 20 21 1 0 0 0 0 21 22 1 0 0 0 0 21 40 1 0 0 0 0 22 23 1 0 0 0 0 22 41 1 0 0 0 0 22 42 1 0 0 0 0 23 24 1 0 0 0 0 23 43 1 0 0 0 0 23 44 1 0 0 0 0 24 27 1 0 0 0 0 24 45 1 0 0 0 0 24 46 1 0 0 0 0 25 28 1 0 0 0 0 25 30 1 0 0 0 0 25 47 1 0 0 0 0 25 48 1 0 0 0 0 26 27 1 0 0 0 0 26 29 1 0 0 0 0 26 49 1 0 0 0 0 26 50 1 0 0 0 0 27 28 1 0 0 0 0 28 51 1 0 0 0 0 28 52 1 0 0 0 0 29 30 1 0 0 0 0 29 53 1 0 0 0 0 29 54 1 0 0 0 0 30 31 1 0 0 0 0 31 55 1 0 0 0 0 31 56 1 0 0 0 0 31 57 1 0 0 0 0 M END > (525) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 31 > (525) PDGFR-beta > (525) 2800 > (525) -1 > (525) P > (525) PDGFR-P523 $$$$ Pyrazine-Pyridine Biheteroaryl 39 csChFnd70/05150717532D 46 48 0 0 0 0 0 0 0 0999 V2000 1.0071 12.0563 -0.0812 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2612 9.9721 -0.3371 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5369 10.7387 -0.3670 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2781 12.8308 -0.1101 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0321 10.6508 -0.1951 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5148 12.1550 -0.2523 N 0 0 0 0 0 0 0 0 0 0 0 0 4.9175 9.9766 -0.5259 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1996 10.7337 -0.5569 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5027 8.6606 -0.8139 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2747 7.8265 -0.7868 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9526 8.4895 -0.6402 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4283 10.0625 -0.6978 N 0 0 0 0 0 0 0 0 0 0 0 0 3.5273 15.0770 0.1142 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6390 16.4242 -0.4973 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6865 14.4942 0.8354 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9477 15.2527 0.9372 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0585 16.5917 0.3226 C 0 0 0 0 0 0 0 0 0 0 0 0 4.9045 17.1782 -0.3918 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0462 18.8625 -1.1555 Cl 0 0 0 0 0 0 0 0 0 0 0 0 2.2495 14.3116 0.0095 N 0 0 3 0 0 0 0 0 0 0 0 0 6.3661 6.3416 -0.9112 N 0 0 3 0 0 0 0 0 0 0 0 0 7.7632 5.6544 -1.0718 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5645 4.0358 -1.1848 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0235 3.3181 -1.3525 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8248 1.6996 -1.4655 C 0 0 0 0 0 0 0 0 0 0 0 0 10.1875 1.0292 -1.6221 O 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 12.6066 0.0394 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2774 8.8222 -0.4303 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1852 11.8838 -0.4650 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5326 8.1530 -0.9276 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9792 7.8705 -0.6151 H 0 0 0 0 0 0 0 0 0 0 0 0 2.7385 16.8821 -1.0548 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6009 13.4488 1.3164 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8488 14.7997 1.4978 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0460 17.1828 0.4045 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3426 14.8131 0.0204 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5047 5.7659 -0.8915 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2819 6.0502 -2.0363 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4255 5.9005 -0.1460 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0457 3.6401 -0.2202 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9022 3.7898 -2.1106 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5422 3.7138 -2.3171 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6858 3.5641 -0.4267 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3061 1.3039 -0.5010 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1625 1.4535 -2.3913 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1431 0.0000 -1.7002 H 0 0 0 0 0 0 0 0 0 0 0 0 1 5 1 0 0 0 0 1 4 2 0 0 0 0 1 27 1 0 0 0 0 2 5 2 0 0 0 0 2 3 1 0 0 0 0 2 28 1 0 0 0 0 3 6 2 0 0 0 0 3 7 1 0 0 0 0 4 6 1 0 0 0 0 4 20 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 12 2 0 0 0 0 8 29 1 0 0 0 0 9 12 1 0 0 0 0 9 10 2 0 0 0 0 9 30 1 0 0 0 0 10 11 1 0 0 0 0 10 21 1 0 0 0 0 11 31 1 0 0 0 0 13 20 1 0 0 0 0 13 14 2 0 0 0 0 13 15 1 0 0 0 0 14 18 1 0 0 0 0 14 32 1 0 0 0 0 15 16 2 0 0 0 0 15 33 1 0 0 0 0 16 17 1 0 0 0 0 16 34 1 0 0 0 0 17 18 2 0 0 0 0 17 35 1 0 0 0 0 18 19 1 0 0 0 0 20 36 1 0 0 0 0 21 22 1 0 0 0 0 21 37 1 0 0 0 0 22 23 1 0 0 0 0 22 38 1 0 0 0 0 22 39 1 0 0 0 0 23 24 1 0 0 0 0 23 40 1 0 0 0 0 23 41 1 0 0 0 0 24 25 1 0 0 0 0 24 42 1 0 0 0 0 24 43 1 0 0 0 0 25 26 1 0 0 0 0 25 44 1 0 0 0 0 25 45 1 0 0 0 0 26 46 1 0 0 0 0 M END > (528) Pyrazine-Pyridine Biheteroaryl 39 > (528) PDGFR-beta > (528) 2800 > (528) -1 > (528) P > (528) PDGFR-P526 $$$$ csChFnd70/05150717532D 41 44 0 0 0 0 0 0 0 0999 V2000 4.0147 8.6821 0.0156 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7232 7.0765 -0.0028 N 0 0 0 0 0 0 0 0 0 0 0 0 4.0348 7.1556 0.0013 N 0 0 0 0 0 0 0 0 0 0 0 0 5.4300 9.4779 0.0214 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8137 8.6108 0.0116 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4829 11.1123 0.0361 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3061 10.9008 0.0323 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5651 11.5341 0.0372 O 0 0 0 0 0 0 0 0 0 0 0 0 8.2210 9.3448 0.0173 N 0 0 3 0 0 0 0 0 0 0 0 0 6.8925 11.8349 0.0407 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9870 13.5464 0.0561 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0229 14.3689 -1.3326 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1105 15.9643 -1.3101 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1625 16.7468 0.0849 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1278 15.9384 1.4656 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0336 14.3432 1.4595 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9810 13.3313 3.1937 Cl 0 0 0 0 0 0 0 0 0 0 0 0 6.9585 13.3890 -3.0847 Cl 0 0 0 0 0 0 0 0 0 0 0 0 5.3605 6.3772 -0.0076 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3150 4.7793 -0.0232 N 0 0 3 0 0 0 0 0 0 0 0 0 3.8988 4.0092 0.1077 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6558 2.6305 -0.6814 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7339 4.6177 1.0325 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3356 3.8544 1.1596 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6460 8.4270 0.0075 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0943 2.4859 0.3678 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2546 1.8724 -0.5495 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9187 0.0000 -1.6303 Br 0 0 0 0 0 0 0 0 0 0 0 0 2.9321 9.3059 0.0176 H 0 0 0 0 0 0 0 0 0 0 0 0 4.4274 11.7810 0.0433 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1388 16.6022 -2.3842 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2309 17.9944 0.0961 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1691 16.5562 2.5510 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2658 4.1918 -0.1249 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5610 2.1518 -1.3977 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9213 5.6866 1.6518 H 0 0 0 0 0 0 0 0 0 0 0 0 0.4278 4.3300 1.8745 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9984 8.2105 -1.1838 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5574 9.0594 0.6072 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4422 7.3282 0.5919 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 1.8912 0.4696 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 29 1 0 0 0 0 2 19 2 0 0 0 0 2 5 1 0 0 0 0 3 19 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 10 2 0 0 0 0 6 30 1 0 0 0 0 7 9 1 0 0 0 0 7 10 1 0 0 0 0 7 8 2 0 0 0 0 9 25 1 0 0 0 0 10 11 1 0 0 0 0 11 16 1 0 0 0 0 11 12 2 0 0 0 0 12 13 1 0 0 0 0 12 18 1 0 0 0 0 13 14 2 0 0 0 0 13 31 1 0 0 0 0 14 15 1 0 0 0 0 14 32 1 0 0 0 0 15 16 2 0 0 0 0 15 33 1 0 0 0 0 16 17 1 0 0 0 0 19 20 1 0 0 0 0 20 21 1 0 0 0 0 20 34 1 0 0 0 0 21 22 1 0 0 0 0 21 23 2 0 0 0 0 22 27 2 0 0 0 0 22 35 1 0 0 0 0 23 24 1 0 0 0 0 23 36 1 0 0 0 0 24 26 2 0 0 0 0 24 37 1 0 0 0 0 25 38 1 0 0 0 0 25 39 1 0 0 0 0 25 40 1 0 0 0 0 26 27 1 0 0 0 0 26 41 1 0 0 0 0 27 28 1 0 0 0 0 M END > (538) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 45 > (538) PDGFR-beta > (538) 3100 > (538) -1 > (538) P > (538) PDGFR-P536 $$$$ Structure23 csChFnd70/05150717532D 86 89 0 0 0 0 0 0 0 0999 V2000 7.7341 3.0758 4.0167 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4938 2.0510 5.3764 C 0 0 0 0 0 0 0 0 0 0 0 0 10.2760 2.3350 5.8935 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3111 3.6416 5.0580 C 0 0 0 0 0 0 0 0 0 0 0 0 10.5689 4.6898 3.6819 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7646 4.4010 3.1606 C 0 0 0 0 0 0 0 0 0 0 0 0 9.9634 6.6615 1.4499 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4026 5.7087 1.6978 C 0 0 0 0 0 0 0 0 0 0 0 0 11.2460 6.0650 2.6161 N 0 0 3 0 0 0 0 0 0 0 0 0 6.6968 5.9394 0.7031 C 0 0 0 0 0 0 0 0 0 0 0 0 5.5580 6.9931 1.2547 O 0 0 0 0 0 0 0 0 0 0 0 0 13.0912 6.7811 2.7312 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3013 8.6003 -0.3283 Se 0 0 0 0 0 0 0 0 0 0 0 0 11.3264 6.9378 -2.8552 Se 0 0 0 0 0 0 0 0 0 0 0 0 11.6643 8.8766 -4.6334 C 0 0 0 0 0 0 0 0 0 0 0 0 13.2256 9.8285 -4.8821 C 0 0 0 0 0 0 0 0 0 0 0 0 12.8636 11.1362 -6.3451 C 0 0 0 0 0 0 0 0 0 0 0 0 11.0590 10.8480 -6.8656 C 0 0 0 0 0 0 0 0 0 0 0 0 13.8945 12.4606 -7.2021 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3174 11.8947 -8.2433 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3495 13.2074 -9.0726 C 0 0 0 0 0 0 0 0 0 0 0 0 13.1346 13.4855 -8.5617 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3843 9.4673 -5.8053 N 0 0 3 0 0 0 0 0 0 0 0 0 8.5417 8.7457 -5.9260 C 0 0 0 0 0 0 0 0 0 0 0 0 16.0695 8.5431 -4.4392 O 0 0 0 0 0 0 0 0 0 0 0 0 14.9315 9.5975 -3.8877 C 0 0 0 0 0 0 0 0 0 0 0 0 15.2359 10.5536 -2.3647 N 0 0 3 0 0 0 0 0 0 0 0 0 6.3932 4.9840 -0.8205 N 0 0 3 0 0 0 0 0 0 0 0 0 4.6921 5.2141 -1.8124 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6918 3.9825 -3.4768 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9861 4.2132 -4.4714 N 0 0 0 0 0 0 0 0 0 0 0 0 2.8497 6.0428 -5.2369 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8868 6.4205 -5.7765 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7953 2.8321 -5.8885 C 0 0 0 0 0 0 0 0 0 0 0 0 16.9371 10.3231 -1.3731 C 0 0 0 0 0 0 0 0 0 0 0 0 16.9385 11.5554 0.2907 C 0 0 0 0 0 0 0 0 0 0 0 0 18.6444 11.3244 1.2850 N 0 0 0 0 0 0 0 0 0 0 0 0 18.8361 12.7061 2.7013 C 0 0 0 0 0 0 0 0 0 0 0 0 19.3528 14.5145 1.8358 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2594 1.0278 -5.0260 C 0 0 0 0 0 0 0 0 0 0 0 0 18.7801 9.4951 2.0513 C 0 0 0 0 0 0 0 0 0 0 0 0 20.7439 9.1149 2.5861 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3480 2.8483 3.6128 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6981 1.0221 6.0431 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8576 1.5246 6.9617 H 0 0 0 0 0 0 0 0 0 0 0 0 12.6970 3.8519 5.4713 H 0 0 0 0 0 0 0 0 0 0 0 0 13.9704 6.0235 1.8209 H 0 0 0 0 0 0 0 0 0 0 0 0 13.0912 8.2043 2.3434 H 0 0 0 0 0 0 0 0 0 0 0 0 13.5846 6.6485 4.1149 H 0 0 0 0 0 0 0 0 0 0 0 0 15.2825 12.6837 -6.8025 H 0 0 0 0 0 0 0 0 0 0 0 0 8.9343 11.6781 -8.6627 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7685 14.0167 -10.1421 H 0 0 0 0 0 0 0 0 0 0 0 0 13.9303 14.5141 -9.2286 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6573 9.5013 -5.0189 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0523 8.8761 -7.3113 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5445 7.3227 -5.5373 H 0 0 0 0 0 0 0 0 0 0 0 0 14.3287 11.3942 -1.9251 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3009 4.1439 -1.2603 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5601 4.8574 -0.9366 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5588 6.6193 -2.2406 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8238 4.3392 -4.3526 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8251 2.5773 -3.0487 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2816 7.0305 -4.2301 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7148 6.1436 -6.4273 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5119 5.5517 -6.9081 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 6.1450 -4.6303 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7497 7.8340 -6.1753 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7522 3.2492 -6.8443 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0787 2.6756 -6.5986 H 0 0 0 0 0 0 0 0 0 0 0 0 17.0699 8.9180 -0.9443 H 0 0 0 0 0 0 0 0 0 0 0 0 18.0691 10.6789 -2.2494 H 0 0 0 0 0 0 0 0 0 0 0 0 16.8057 12.9605 -0.1380 H 0 0 0 0 0 0 0 0 0 0 0 0 15.8065 11.1996 1.1670 H 0 0 0 0 0 0 0 0 0 0 0 0 17.5570 12.8532 3.4213 H 0 0 0 0 0 0 0 0 0 0 0 0 19.8893 12.2958 3.6490 H 0 0 0 0 0 0 0 0 0 0 0 0 19.6569 15.4967 2.8934 H 0 0 0 0 0 0 0 0 0 0 0 0 20.5404 14.3290 0.9810 H 0 0 0 0 0 0 0 0 0 0 0 0 18.2292 15.0063 1.0164 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9700 1.1810 -4.3262 H 0 0 0 0 0 0 0 0 0 0 0 0 2.1299 0.0000 -6.0759 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2966 0.6168 -4.0610 H 0 0 0 0 0 0 0 0 0 0 0 0 17.9178 9.3963 3.2439 H 0 0 0 0 0 0 0 0 0 0 0 0 18.3442 8.5073 1.0462 H 0 0 0 0 0 0 0 0 0 0 0 0 21.1322 10.0047 3.6965 H 0 0 0 0 0 0 0 0 0 0 0 0 20.8736 7.7092 3.0139 H 0 0 0 0 0 0 0 0 0 0 0 0 21.6249 9.3597 1.4286 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 6 1 0 0 0 0 1 43 1 0 0 0 0 2 3 1 0 0 0 0 2 44 1 0 0 0 0 3 4 2 0 0 0 0 3 45 1 0 0 0 0 4 5 1 0 0 0 0 4 46 1 0 0 0 0 5 9 1 0 0 0 0 5 6 2 0 0 0 0 6 8 1 0 0 0 0 7 9 1 0 0 0 0 7 8 2 0 0 0 0 7 13 1 0 0 0 0 8 10 1 0 0 0 0 9 12 1 0 0 0 0 10 11 2 0 0 0 0 10 28 1 0 0 0 0 12 47 1 0 0 0 0 12 48 1 0 0 0 0 12 49 1 0 0 0 0 13 14 1 0 0 0 0 14 15 1 0 0 0 0 15 16 2 0 0 0 0 15 23 1 0 0 0 0 16 17 1 0 0 0 0 16 26 1 0 0 0 0 17 19 2 0 0 0 0 17 18 1 0 0 0 0 18 23 1 0 0 0 0 18 20 2 0 0 0 0 19 22 1 0 0 0 0 19 50 1 0 0 0 0 20 21 1 0 0 0 0 20 51 1 0 0 0 0 21 22 2 0 0 0 0 21 52 1 0 0 0 0 22 53 1 0 0 0 0 23 24 1 0 0 0 0 24 54 1 0 0 0 0 24 55 1 0 0 0 0 24 56 1 0 0 0 0 25 26 2 0 0 0 0 26 27 1 0 0 0 0 27 35 1 0 0 0 0 27 57 1 0 0 0 0 28 29 1 0 0 0 0 28 58 1 0 0 0 0 29 30 1 0 0 0 0 29 59 1 0 0 0 0 29 60 1 0 0 0 0 30 31 1 0 0 0 0 30 61 1 0 0 0 0 30 62 1 0 0 0 0 31 32 1 0 0 0 0 31 34 1 0 0 0 0 32 33 1 0 0 0 0 32 63 1 0 0 0 0 32 64 1 0 0 0 0 33 65 1 0 0 0 0 33 66 1 0 0 0 0 33 67 1 0 0 0 0 34 40 1 0 0 0 0 34 68 1 0 0 0 0 34 69 1 0 0 0 0 35 36 1 0 0 0 0 35 70 1 0 0 0 0 35 71 1 0 0 0 0 36 37 1 0 0 0 0 36 72 1 0 0 0 0 36 73 1 0 0 0 0 37 38 1 0 0 0 0 37 41 1 0 0 0 0 38 39 1 0 0 0 0 38 74 1 0 0 0 0 38 75 1 0 0 0 0 39 76 1 0 0 0 0 39 77 1 0 0 0 0 39 78 1 0 0 0 0 40 79 1 0 0 0 0 40 80 1 0 0 0 0 40 81 1 0 0 0 0 41 42 1 0 0 0 0 41 82 1 0 0 0 0 41 83 1 0 0 0 0 42 84 1 0 0 0 0 42 85 1 0 0 0 0 42 86 1 0 0 0 0 M END > (554) diselenobis(1H-indole) deriv. 24 > (554) PDGFR-beta > (554) 3400 > (554) -1 > (554) P > (554) PDGFR-P552 $$$$ csChFnd70/05150717532D 37 39 0 0 0 0 0 0 0 0999 V2000 1.2022 7.8332 0.0119 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2096 6.0519 -0.0263 N 0 0 0 0 0 0 0 0 0 0 0 0 1.2252 6.1382 0.0026 N 0 0 0 0 0 0 0 0 0 0 0 0 2.7728 8.7173 0.0017 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3093 7.7555 -0.0181 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8308 10.5320 0.0103 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9649 10.2987 -0.0214 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3623 11.0025 -0.0316 O 0 0 0 0 0 0 0 0 0 0 0 0 5.8713 8.5712 -0.0293 N 0 0 3 0 0 0 0 0 0 0 0 0 7.4535 7.5529 -0.0492 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3952 11.3350 -0.0009 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4992 13.2352 0.0082 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5256 14.1426 -1.5372 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6222 15.9139 -1.5196 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6932 16.7883 0.0254 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6682 15.8965 1.5619 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5639 14.1255 1.5624 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5232 13.0091 3.4923 Cl 0 0 0 0 0 0 0 0 0 0 0 0 4.4380 13.0475 -3.4775 Cl 0 0 0 0 0 0 0 0 0 0 0 0 2.6972 5.2748 -0.0161 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6476 3.5022 -0.0257 N 0 0 3 0 0 0 0 0 0 0 0 0 0.9924 2.6073 -0.0154 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2973 0.6659 -0.0293 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 8.5251 0.0214 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6587 11.2739 0.0250 H 0 0 0 0 0 0 0 0 0 0 0 0 7.8333 7.3065 -1.3741 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4709 8.2585 0.6043 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2336 6.3359 0.6072 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6426 16.6177 -2.7148 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7691 18.1734 0.0321 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7246 16.5868 2.7639 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7087 2.8494 -0.0394 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2787 2.9594 1.1365 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2574 2.9723 -1.1496 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0109 0.3138 -1.1812 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0323 0.3008 1.1049 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0658 0.0000 -0.0216 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 24 1 0 0 0 0 2 20 2 0 0 0 0 2 5 1 0 0 0 0 3 20 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 11 2 0 0 0 0 6 25 1 0 0 0 0 7 9 1 0 0 0 0 7 11 1 0 0 0 0 7 8 2 0 0 0 0 9 10 1 0 0 0 0 10 26 1 0 0 0 0 10 27 1 0 0 0 0 10 28 1 0 0 0 0 11 12 1 0 0 0 0 12 17 1 0 0 0 0 12 13 2 0 0 0 0 13 14 1 0 0 0 0 13 19 1 0 0 0 0 14 15 2 0 0 0 0 14 29 1 0 0 0 0 15 16 1 0 0 0 0 15 30 1 0 0 0 0 16 17 2 0 0 0 0 16 31 1 0 0 0 0 17 18 1 0 0 0 0 20 21 1 0 0 0 0 21 22 1 0 0 0 0 21 32 1 0 0 0 0 22 23 1 0 0 0 0 22 33 1 0 0 0 0 22 34 1 0 0 0 0 23 35 1 0 0 0 0 23 36 1 0 0 0 0 23 37 1 0 0 0 0 M END > (575) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 22 > (575) PDGFR-beta > (575) 4000 > (575) -1 > (575) P > (575) PDGFR-P573 $$$$ Structure119 csChFnd70/05150717532D 62 65 0 0 0 0 0 0 0 0999 V2000 11.9058 10.7882 -1.0926 N 0 0 0 0 0 0 0 0 0 0 0 0 13.0094 11.7356 -1.9851 C 0 0 0 0 0 0 0 0 0 0 0 0 14.5512 11.1677 -2.4250 N 0 0 0 0 0 0 0 0 0 0 0 0 15.0570 9.6003 -1.9800 C 0 0 0 0 0 0 0 0 0 0 0 0 13.9195 8.5550 -1.0305 C 0 0 0 0 0 0 0 0 0 0 0 0 12.3002 9.2159 -0.5962 C 0 0 0 0 0 0 0 0 0 0 0 0 16.6524 9.0016 -2.4296 N 0 0 3 0 0 0 0 0 0 0 0 0 17.1589 7.4112 -1.9743 C 0 0 0 0 0 0 0 0 0 0 0 0 16.0102 6.2940 -0.9893 C 0 0 0 0 0 0 0 0 0 0 0 0 14.4152 6.8799 -0.5357 C 0 0 0 0 0 0 0 0 0 0 0 0 16.5687 4.5451 -0.4883 C 0 0 0 0 0 0 0 0 0 0 0 0 16.2494 3.1534 -1.5719 C 0 0 0 0 0 0 0 0 0 0 0 0 16.7740 1.5266 -1.0977 C 0 0 0 0 0 0 0 0 0 0 0 0 17.6136 1.2748 0.4479 C 0 0 0 0 0 0 0 0 0 0 0 0 17.9335 2.6488 1.5281 C 0 0 0 0 0 0 0 0 0 0 0 0 17.4227 4.2835 1.0654 C 0 0 0 0 0 0 0 0 0 0 0 0 18.5800 6.9002 -2.3831 O 0 0 0 0 0 0 0 0 0 0 0 0 15.1946 3.4665 -3.5113 Cl 0 0 0 0 0 0 0 0 0 0 0 0 17.8167 10.1032 -3.4156 C 0 0 0 0 0 0 0 0 0 0 0 0 17.8255 6.0061 2.4229 Cl 0 0 0 0 0 0 0 0 0 0 0 0 12.5305 13.3730 -2.4727 N 0 0 3 0 0 0 0 0 0 0 0 0 10.8623 13.9579 -2.1423 C 0 0 0 0 0 0 0 0 0 0 0 0 10.5773 15.6792 -1.7713 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9315 16.2550 -1.4455 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5632 15.1147 -1.4892 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8468 13.3951 -1.8597 C 0 0 0 0 0 0 0 0 0 0 0 0 9.4908 12.8186 -2.1929 C 0 0 0 0 0 0 0 0 0 0 0 0 5.9431 15.6827 -1.1677 O 0 0 0 0 0 0 0 0 0 0 0 0 2.8787 15.3105 -0.8411 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4782 16.5534 -2.2031 N 0 0 0 0 0 0 0 0 0 0 0 0 2.1717 15.6796 -3.8470 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2709 16.9860 -5.3118 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0043 17.6297 -1.7242 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5730 18.9696 -0.4040 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5954 14.4384 -1.2342 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3955 8.4541 0.1286 H 0 0 0 0 0 0 0 0 0 0 0 0 13.5497 6.0752 0.1906 H 0 0 0 0 0 0 0 0 0 0 0 0 16.5277 0.4484 -1.9350 H 0 0 0 0 0 0 0 0 0 0 0 0 18.0206 0.0000 0.8129 H 0 0 0 0 0 0 0 0 0 0 0 0 18.5893 2.4435 2.7332 H 0 0 0 0 0 0 0 0 0 0 0 0 18.6027 10.8570 -2.5357 H 0 0 0 0 0 0 0 0 0 0 0 0 18.6449 9.3080 -4.2168 H 0 0 0 0 0 0 0 0 0 0 0 0 17.0687 10.9642 -4.2276 H 0 0 0 0 0 0 0 0 0 0 0 0 13.3501 14.1176 -3.0439 H 0 0 0 0 0 0 0 0 0 0 0 0 11.6425 16.5672 -1.7368 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7098 17.5936 -1.1564 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7809 12.5081 -1.8930 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7114 11.4799 -2.4815 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9640 15.9761 0.3876 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8677 14.3440 -0.7791 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1436 14.6899 -4.0379 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9019 15.0900 -3.8327 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3149 17.9884 -5.1085 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5483 17.5584 -5.3410 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0200 16.3420 -6.5294 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5097 18.2770 -2.8629 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 16.8264 -1.1710 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9500 18.3263 0.7809 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6610 19.6909 -0.9100 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5131 19.8461 -0.1424 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5480 13.8696 -2.5126 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8377 13.4368 -0.2864 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 2 3 1 0 0 0 0 2 21 1 0 0 0 0 3 4 2 0 0 0 0 4 7 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 5 6 2 0 0 0 0 6 36 1 0 0 0 0 7 8 1 0 0 0 0 7 19 1 0 0 0 0 8 9 1 0 0 0 0 8 17 2 0 0 0 0 9 11 1 0 0 0 0 9 10 2 0 0 0 0 10 37 1 0 0 0 0 11 12 2 0 0 0 0 11 16 1 0 0 0 0 12 13 1 0 0 0 0 12 18 1 0 0 0 0 13 14 2 0 0 0 0 13 38 1 0 0 0 0 14 15 1 0 0 0 0 14 39 1 0 0 0 0 15 16 2 0 0 0 0 15 40 1 0 0 0 0 16 20 1 0 0 0 0 19 41 1 0 0 0 0 19 42 1 0 0 0 0 19 43 1 0 0 0 0 21 22 1 0 0 0 0 21 44 1 0 0 0 0 22 23 2 0 0 0 0 22 27 1 0 0 0 0 23 24 1 0 0 0 0 23 45 1 0 0 0 0 24 25 2 0 0 0 0 24 46 1 0 0 0 0 25 26 1 0 0 0 0 25 28 1 0 0 0 0 26 27 2 0 0 0 0 26 47 1 0 0 0 0 27 48 1 0 0 0 0 28 35 1 0 0 0 0 29 30 1 0 0 0 0 29 35 1 0 0 0 0 29 49 1 0 0 0 0 29 50 1 0 0 0 0 30 31 1 0 0 0 0 30 33 1 0 0 0 0 31 32 1 0 0 0 0 31 51 1 0 0 0 0 31 52 1 0 0 0 0 32 53 1 0 0 0 0 32 54 1 0 0 0 0 32 55 1 0 0 0 0 33 34 1 0 0 0 0 33 56 1 0 0 0 0 33 57 1 0 0 0 0 34 58 1 0 0 0 0 34 59 1 0 0 0 0 34 60 1 0 0 0 0 35 61 1 0 0 0 0 35 62 1 0 0 0 0 M END > (583) 17964795-21 > (583) PDGFR-beta > (583) 4020 > (583) -1 > (583) P > (583) PDGFR-P581 $$$$ Structure115 csChFnd70/05150717532D 47 50 0 0 0 0 0 0 0 0999 V2000 6.1669 10.1577 -0.6065 N 0 0 0 0 0 0 0 0 0 0 0 0 7.3562 10.8963 -0.1948 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6395 10.2479 0.0253 N 0 0 0 0 0 0 0 0 0 0 0 0 8.7843 8.8082 -0.1618 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5445 7.9857 -0.5992 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2096 8.7241 -0.8181 C 0 0 0 0 0 0 0 0 0 0 0 0 10.1096 8.1271 0.0642 N 0 0 3 0 0 0 0 0 0 0 0 0 10.2500 6.6666 -0.1269 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9856 5.7812 -0.5800 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6590 6.4515 -0.8097 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1410 4.1748 -0.7897 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5325 3.6117 -2.1605 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6760 2.1131 -2.3483 C 0 0 0 0 0 0 0 0 0 0 0 0 9.4321 1.1710 -1.1814 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0431 1.7219 0.1801 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9026 3.2187 0.3845 C 0 0 0 0 0 0 0 0 0 0 0 0 11.4344 6.0791 0.0794 O 0 0 0 0 0 0 0 0 0 0 0 0 9.8380 4.7922 -3.6266 Cl 0 0 0 0 0 0 0 0 0 0 0 0 11.3853 8.9972 0.5171 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4145 3.9081 2.0941 Cl 0 0 0 0 0 0 0 0 0 0 0 0 7.2503 12.3964 0.0110 N 0 0 3 0 0 0 0 0 0 0 0 0 5.8842 13.0906 -0.0886 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6220 12.3633 0.3656 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2742 13.0522 0.2656 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1801 14.4645 -0.2859 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4344 15.1914 -0.7396 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7865 14.5114 -0.6362 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7075 15.2128 -0.3935 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4034 16.0366 1.0098 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2914 16.0180 1.9960 O 0 0 0 0 0 0 0 0 0 0 0 0 0.1460 16.7910 1.1642 O 0 0 0 0 0 0 0 0 0 0 0 0 5.2378 8.1320 -1.1532 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7138 5.8174 -1.1441 H 0 0 0 0 0 0 0 0 0 0 0 0 9.9790 1.6759 -3.4088 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5453 0.0000 -1.3342 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8537 0.9805 1.0866 H 0 0 0 0 0 0 0 0 0 0 0 0 11.4311 9.0457 1.7126 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3849 8.4872 0.0999 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2889 10.1062 0.0761 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1239 12.9678 0.2245 H 0 0 0 0 0 0 0 0 0 0 0 0 4.6947 11.2602 0.7959 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2924 12.4872 0.6181 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3572 16.2942 -1.1702 H 0 0 0 0 0 0 0 0 0 0 0 0 6.7657 15.0797 -0.9907 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7156 15.9797 -1.3128 H 0 0 0 0 0 0 0 0 0 0 0 0 0.8539 14.3910 -0.5667 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 17.3020 2.0838 H 0 0 0 0 0 0 0 0 0 0 0 0 1 6 1 0 0 0 0 1 2 2 0 0 0 0 2 3 1 0 0 0 0 2 21 1 0 0 0 0 3 4 2 0 0 0 0 4 7 1 0 0 0 0 4 5 1 0 0 0 0 5 10 1 0 0 0 0 5 6 2 0 0 0 0 6 32 1 0 0 0 0 7 8 1 0 0 0 0 7 19 1 0 0 0 0 8 9 1 0 0 0 0 8 17 2 0 0 0 0 9 11 1 0 0 0 0 9 10 2 0 0 0 0 10 33 1 0 0 0 0 11 12 2 0 0 0 0 11 16 1 0 0 0 0 12 13 1 0 0 0 0 12 18 1 0 0 0 0 13 14 2 0 0 0 0 13 34 1 0 0 0 0 14 15 1 0 0 0 0 14 35 1 0 0 0 0 15 16 2 0 0 0 0 15 36 1 0 0 0 0 16 20 1 0 0 0 0 19 37 1 0 0 0 0 19 38 1 0 0 0 0 19 39 1 0 0 0 0 21 22 1 0 0 0 0 21 40 1 0 0 0 0 22 23 2 0 0 0 0 22 27 1 0 0 0 0 23 24 1 0 0 0 0 23 41 1 0 0 0 0 24 25 2 0 0 0 0 24 42 1 0 0 0 0 25 26 1 0 0 0 0 25 28 1 0 0 0 0 26 27 2 0 0 0 0 26 43 1 0 0 0 0 27 44 1 0 0 0 0 28 29 1 0 0 0 0 28 45 1 0 0 0 0 28 46 1 0 0 0 0 29 30 2 0 0 0 0 29 31 1 0 0 0 0 31 47 1 0 0 0 0 M END > (586) 17964795-8 > (586) PDGFR-beta > (586) 4150 > (586) -1 > (586) P > (586) PDGFR-P584 $$$$ Structure439 csChFnd70/05150717532D 44 46 0 0 0 0 0 0 0 0999 V2000 2.4121 4.3925 0.0455 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4400 2.8379 -0.0841 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7693 2.0882 -0.2298 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1053 2.8902 -0.2483 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0682 4.4614 -0.1167 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7024 5.1968 0.0300 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4297 2.2127 -0.3872 N 0 0 0 0 0 0 0 0 0 0 0 0 7.6630 2.9940 -0.4005 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6828 4.4621 -0.2805 N 0 0 0 0 0 0 0 0 0 0 0 0 6.4366 5.2415 -0.1386 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0181 8.9073 -0.5431 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8407 7.5118 0.0966 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0191 6.8500 0.8466 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3690 7.5788 0.9572 C 0 0 0 0 0 0 0 0 0 0 0 0 10.5496 8.9715 0.3201 C 0 0 0 0 0 0 0 0 0 0 0 0 9.3710 9.6378 -0.4321 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4739 6.7722 -0.0139 N 0 0 3 0 0 0 0 0 0 0 0 0 1.0856 5.1084 0.1819 O 0 0 0 0 0 0 0 0 0 0 0 0 1.1301 6.6931 0.3097 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1421 2.0624 -0.0654 O 0 0 0 0 0 0 0 0 0 0 0 0 1.2438 0.4811 -0.2020 C 0 0 0 0 0 0 0 0 0 0 0 0 9.5476 11.0046 -1.0582 O 0 0 0 0 0 0 0 0 0 0 0 0 8.2906 11.6209 -1.8130 C 0 0 0 0 0 0 0 0 0 0 0 0 11.8796 9.6879 0.4300 O 0 0 0 0 0 0 0 0 0 0 0 0 13.0404 8.9385 1.2178 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7810 0.8902 -0.3288 H 0 0 0 0 0 0 0 0 0 0 0 0 3.6689 6.3942 0.1303 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7093 2.4131 -0.5140 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1035 9.4205 -1.1306 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8803 5.7645 1.3443 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2840 7.0624 1.5412 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5528 7.3355 -0.0030 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 7.1225 0.4110 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7696 7.0017 1.2935 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6546 7.1640 -0.6777 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7766 0.1994 -1.2549 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9018 0.0374 0.7156 H 0 0 0 0 0 0 0 0 0 0 0 0 0.1304 0.0000 -0.1708 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5813 12.7109 -2.2592 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9640 10.8860 -2.7214 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3675 11.7359 -1.0341 H 0 0 0 0 0 0 0 0 0 0 0 0 12.6862 8.7317 2.3596 H 0 0 0 0 0 0 0 0 0 0 0 0 13.2830 7.8824 0.6722 H 0 0 0 0 0 0 0 0 0 0 0 0 14.0374 9.6297 1.2226 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 6 1 0 0 0 0 1 18 1 0 0 0 0 2 3 1 0 0 0 0 2 20 1 0 0 0 0 3 4 2 0 0 0 0 3 26 1 0 0 0 0 4 5 1 0 0 0 0 4 7 1 0 0 0 0 5 6 2 0 0 0 0 5 10 1 0 0 0 0 6 27 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 8 28 1 0 0 0 0 9 10 2 0 0 0 0 10 17 1 0 0 0 0 11 12 2 0 0 0 0 11 16 1 0 0 0 0 11 29 1 0 0 0 0 12 13 1 0 0 0 0 12 17 1 0 0 0 0 13 14 2 0 0 0 0 13 30 1 0 0 0 0 14 15 1 0 0 0 0 14 31 1 0 0 0 0 15 16 2 0 0 0 0 15 24 1 0 0 0 0 16 22 1 0 0 0 0 17 32 1 0 0 0 0 18 19 1 0 0 0 0 19 33 1 0 0 0 0 19 34 1 0 0 0 0 19 35 1 0 0 0 0 20 21 1 0 0 0 0 21 36 1 0 0 0 0 21 37 1 0 0 0 0 21 38 1 0 0 0 0 22 23 1 0 0 0 0 23 39 1 0 0 0 0 23 40 1 0 0 0 0 23 41 1 0 0 0 0 24 25 1 0 0 0 0 25 42 1 0 0 0 0 25 43 1 0 0 0 0 25 44 1 0 0 0 0 M END > (603) 15-9b > (603) PDGFR-beta > (603) 4500 > (603) -1 > (603) P > (603) PDGFR-P601 $$$$ Structure134 csChFnd70/05150717532D 45 47 0 0 0 0 0 0 0 0999 V2000 2.5953 9.5774 0.0119 N 0 0 0 0 0 0 0 0 0 0 0 0 2.6185 7.8676 0.0026 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0567 6.9713 -0.0154 N 0 0 0 0 0 0 0 0 0 0 0 0 5.5792 7.7710 -0.0257 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6015 9.5945 -0.0167 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0503 6.8925 -0.0435 N 0 0 0 0 0 0 0 0 0 0 0 0 8.5494 7.6776 -0.0530 C 0 0 0 0 0 0 0 0 0 0 0 0 8.6706 9.4856 -0.0448 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0422 6.7047 -0.0702 N 0 0 3 0 0 0 0 0 0 0 0 0 9.9488 4.9761 -0.0782 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3989 4.0310 -0.0950 N 0 0 3 0 0 0 0 0 0 0 0 0 8.5564 4.2695 -0.0704 O 0 0 0 0 0 0 0 0 0 0 0 0 1.0726 6.9957 0.0127 N 0 0 0 0 0 0 0 0 0 0 0 0 10.3756 10.3338 -0.0552 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7268 11.6313 -1.2379 C 0 0 0 0 0 0 0 0 0 0 0 0 12.3161 12.4161 -1.2416 C 0 0 0 0 0 0 0 0 0 0 0 0 13.5596 11.9175 -0.0746 C 0 0 0 0 0 0 0 0 0 0 0 0 13.2187 10.6302 1.1016 C 0 0 0 0 0 0 0 0 0 0 0 0 11.6312 9.8417 1.1226 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0277 10.4788 0.0032 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1823 10.4623 -0.0271 C 0 0 0 0 0 0 0 0 0 0 0 0 11.2973 2.1521 -0.1036 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3238 1.5561 -1.7033 C 0 0 0 0 0 0 0 0 0 0 0 0 13.1120 1.3980 -0.1225 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3502 1.5399 1.5056 C 0 0 0 0 0 0 0 0 0 0 0 0 11.1532 7.2685 -0.0766 H 0 0 0 0 0 0 0 0 0 0 0 0 12.5100 4.5947 -0.1013 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0600 5.7498 0.0066 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 7.6294 0.0259 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7571 12.0213 -2.1500 H 0 0 0 0 0 0 0 0 0 0 0 0 12.5897 13.4211 -2.1577 H 0 0 0 0 0 0 0 0 0 0 0 0 14.8016 12.5352 -0.0822 H 0 0 0 0 0 0 0 0 0 0 0 0 14.1946 10.2455 2.0092 H 0 0 0 0 0 0 0 0 0 0 0 0 11.3663 8.8372 2.0418 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9932 11.8656 0.0105 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2369 11.8485 -0.0209 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9984 1.9923 -2.8499 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2481 0.1581 -1.7098 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0310 2.0934 -1.6899 H 0 0 0 0 0 0 0 0 0 0 0 0 13.8055 1.8226 1.0171 H 0 0 0 0 0 0 0 0 0 0 0 0 13.0364 0.0000 -0.1290 H 0 0 0 0 0 0 0 0 0 0 0 0 13.7868 1.8341 -1.2690 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0574 2.0770 1.5190 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2745 0.1419 1.4992 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0438 1.9644 2.6452 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 20 2 0 0 0 0 2 3 2 0 0 0 0 2 13 1 0 0 0 0 3 4 1 0 0 0 0 4 6 2 0 0 0 0 4 5 1 0 0 0 0 5 20 1 0 0 0 0 5 21 2 0 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 7 9 1 0 0 0 0 8 14 1 0 0 0 0 8 21 1 0 0 0 0 9 10 1 0 0 0 0 9 26 1 0 0 0 0 10 11 1 0 0 0 0 10 12 2 0 0 0 0 11 22 1 0 0 0 0 11 27 1 0 0 0 0 13 28 1 0 0 0 0 13 29 1 0 0 0 0 14 15 2 0 0 0 0 14 19 1 0 0 0 0 15 16 1 0 0 0 0 15 30 1 0 0 0 0 16 17 2 0 0 0 0 16 31 1 0 0 0 0 17 18 1 0 0 0 0 17 32 1 0 0 0 0 18 19 2 0 0 0 0 18 33 1 0 0 0 0 19 34 1 0 0 0 0 20 35 1 0 0 0 0 21 36 1 0 0 0 0 22 23 1 0 0 0 0 22 24 1 0 0 0 0 22 25 1 0 0 0 0 23 37 1 0 0 0 0 23 38 1 0 0 0 0 23 39 1 0 0 0 0 24 40 1 0 0 0 0 24 41 1 0 0 0 0 24 42 1 0 0 0 0 25 43 1 0 0 0 0 25 44 1 0 0 0 0 25 45 1 0 0 0 0 M END > (609) 9240345-4a > (609) PDGFR-beta > (609) 4670 > (609) -1 > (609) P > (609) PDGFR-P607 $$$$ Structure26 csChFnd70/05150717532D 52 55 0 0 0 0 0 0 0 0999 V2000 1.7362 3.2462 0.0099 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7556 1.8225 0.0021 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0031 1.1161 -0.0131 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2382 1.8247 -0.0211 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2405 3.2623 -0.0138 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9769 3.9757 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7416 5.5284 -0.0065 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3341 5.4570 0.0065 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2814 4.2366 -0.0195 N 0 0 3 0 0 0 0 0 0 0 0 0 2.3649 6.6255 0.0216 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9735 7.1037 1.1168 O 0 0 0 0 0 0 0 0 0 0 0 0 6.7616 3.9191 -0.0350 C 0 0 0 0 0 0 0 0 0 0 0 0 5.8213 7.2423 -0.0084 Se 0 0 0 0 0 0 0 0 0 0 0 0 6.0448 7.6490 -2.4027 Se 0 0 0 0 0 0 0 0 0 0 0 0 7.1245 9.3629 -2.4046 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5320 9.4344 -2.4185 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8893 10.9157 -2.4143 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6257 11.6290 -2.3975 C 0 0 0 0 0 0 0 0 0 0 0 0 10.1298 11.6451 -2.4230 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6278 13.0666 -2.3921 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8630 13.7752 -2.3929 C 0 0 0 0 0 0 0 0 0 0 0 0 10.1104 13.0689 -2.4151 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5847 10.6547 -2.3982 N 0 0 3 0 0 0 0 0 0 0 0 0 5.1043 10.9722 -2.3889 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8918 7.7874 -3.5293 O 0 0 0 0 0 0 0 0 0 0 0 0 9.5012 8.2658 -2.4340 C 0 0 0 0 0 0 0 0 0 0 0 0 9.9577 7.7237 -1.2350 N 0 0 3 0 0 0 0 0 0 0 0 0 10.9242 6.5583 -1.2504 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9092 7.1680 -1.1776 N 0 0 3 0 0 0 0 0 0 0 0 0 0.9427 8.3332 -1.1627 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7637 3.7940 0.0175 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7952 1.2539 0.0082 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0062 0.0000 -0.0184 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2036 1.2646 -0.0327 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1187 3.8451 -1.1010 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3268 4.7372 0.4943 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9409 2.9387 0.4900 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1023 11.0975 -2.4355 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6624 13.6267 -2.3875 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8598 14.8914 -2.3891 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0708 13.6376 -2.4215 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7435 11.0487 -1.3245 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9270 11.9514 -2.9168 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5412 10.1529 -2.9183 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6463 8.1051 -0.3617 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1744 6.2639 -0.1922 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4507 5.6848 -1.7812 H 0 0 0 0 0 0 0 0 0 0 0 0 11.8666 6.8592 -1.7893 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2212 6.7867 -2.0507 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 8.0323 -0.6245 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4159 9.2066 -0.6312 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6933 8.6279 -2.2209 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 6 1 0 0 0 0 1 31 1 0 0 0 0 2 3 1 0 0 0 0 2 32 1 0 0 0 0 3 4 2 0 0 0 0 3 33 1 0 0 0 0 4 5 1 0 0 0 0 4 34 1 0 0 0 0 5 9 1 0 0 0 0 5 6 2 0 0 0 0 6 8 1 0 0 0 0 7 9 1 0 0 0 0 7 8 2 0 0 0 0 7 13 1 0 0 0 0 8 10 1 0 0 0 0 9 12 1 0 0 0 0 10 11 2 0 0 0 0 10 29 1 0 0 0 0 12 35 1 0 0 0 0 12 36 1 0 0 0 0 12 37 1 0 0 0 0 13 14 1 0 0 0 0 14 15 1 0 0 0 0 15 16 2 0 0 0 0 15 23 1 0 0 0 0 16 17 1 0 0 0 0 16 26 1 0 0 0 0 17 19 2 0 0 0 0 17 18 1 0 0 0 0 18 23 1 0 0 0 0 18 20 2 0 0 0 0 19 22 1 0 0 0 0 19 38 1 0 0 0 0 20 21 1 0 0 0 0 20 39 1 0 0 0 0 21 22 2 0 0 0 0 21 40 1 0 0 0 0 22 41 1 0 0 0 0 23 24 1 0 0 0 0 24 42 1 0 0 0 0 24 43 1 0 0 0 0 24 44 1 0 0 0 0 25 26 2 0 0 0 0 26 27 1 0 0 0 0 27 28 1 0 0 0 0 27 45 1 0 0 0 0 28 46 1 0 0 0 0 28 47 1 0 0 0 0 28 48 1 0 0 0 0 29 30 1 0 0 0 0 29 49 1 0 0 0 0 30 50 1 0 0 0 0 30 51 1 0 0 0 0 30 52 1 0 0 0 0 M END > (611) diselenobis(1H-indole) deriv. 23 > (611) PDGFR-beta > (611) 4700 > (611) -1 > (611) P > (611) PDGFR-P609 $$$$ pyrrolo[2,3-d]pyrimidin-6-one deriv. 26t csChFnd70/05150717532D 63 66 0 0 0 0 0 0 0 0999 V2000 7.0137 3.6184 -1.2362 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0027 1.2330 -1.8195 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8922 2.0924 -1.2521 N 0 0 0 0 0 0 0 0 0 0 0 0 9.2756 1.8159 -2.3944 N 0 0 0 0 0 0 0 0 0 0 0 0 9.5018 3.3293 -2.4288 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3471 4.2851 -1.8357 C 0 0 0 0 0 0 0 0 0 0 0 0 10.4213 5.7274 -2.7490 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8984 5.8773 -2.0203 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7017 4.2221 -2.9543 N 0 0 3 0 0 0 0 0 0 0 0 0 11.2723 6.7792 -3.1023 O 0 0 0 0 0 0 0 0 0 0 0 0 5.8455 4.5223 -0.6466 N 0 0 3 0 0 0 0 0 0 0 0 0 4.4595 3.8472 -0.1888 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1275 3.9400 1.2812 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7182 2.5114 0.7163 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6789 1.7473 -0.2940 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0472 2.4113 -0.7475 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1543 7.2109 -1.6046 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9328 8.6364 -1.6880 C 0 0 0 0 0 0 0 0 0 0 0 0 10.7857 10.3977 -1.6289 C 0 0 0 0 0 0 0 0 0 0 0 0 9.4312 11.1436 -1.9890 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2701 10.0465 -2.0242 C 0 0 0 0 0 0 0 0 0 0 0 0 10.4711 8.8651 -1.4442 N 0 0 3 0 0 0 0 0 0 0 0 0 6.5976 10.3364 -2.3658 C 0 0 0 0 0 0 0 0 0 0 0 0 12.3025 11.1234 -1.4675 C 0 0 0 0 0 0 0 0 0 0 0 0 12.4423 12.5007 -1.6596 O 0 0 0 0 0 0 0 0 0 0 0 0 13.5380 10.2626 -1.1066 N 0 0 3 0 0 0 0 0 0 0 0 0 15.0494 10.9856 -0.9457 C 0 0 0 0 0 0 0 0 0 0 0 0 16.2433 9.7625 -0.5351 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4959 4.6106 0.8317 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8961 6.0051 1.3834 F 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 1.6721 1.2833 Cl 0 0 0 0 0 0 0 0 0 0 0 0 17.7588 10.4876 -0.3737 N 0 0 0 0 0 0 0 0 0 0 0 0 18.8788 9.4085 0.2819 C 0 0 0 0 0 0 0 0 0 0 0 0 18.5845 9.2346 2.0062 C 0 0 0 0 0 0 0 0 0 0 0 0 18.2990 11.0955 -1.8526 C 0 0 0 0 0 0 0 0 0 0 0 0 19.7301 12.0825 -1.5928 C 0 0 0 0 0 0 0 0 0 0 0 0 7.8635 0.0000 -1.8124 H 0 0 0 0 0 0 0 0 0 0 0 0 11.6316 3.8147 -3.4139 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9874 5.6235 -0.5507 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3754 4.5340 2.0694 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3561 0.6324 -0.7324 H 0 0 0 0 0 0 0 0 0 0 0 0 4.7957 1.8137 -1.5364 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9770 7.1689 -1.2150 H 0 0 0 0 0 0 0 0 0 0 0 0 9.2982 12.3584 -2.2036 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2131 8.0755 -1.1837 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9906 10.5844 -1.2989 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4934 11.3134 -3.1422 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0993 9.3210 -2.9033 H 0 0 0 0 0 0 0 0 0 0 0 0 13.4266 9.1644 -0.9533 H 0 0 0 0 0 0 0 0 0 0 0 0 15.3673 11.5333 -2.0261 H 0 0 0 0 0 0 0 0 0 0 0 0 15.0054 11.8473 -0.0379 H 0 0 0 0 0 0 0 0 0 0 0 0 15.9254 9.2149 0.5453 H 0 0 0 0 0 0 0 0 0 0 0 0 16.2873 8.9008 -1.4428 H 0 0 0 0 0 0 0 0 0 0 0 0 18.7606 8.2938 -0.2762 H 0 0 0 0 0 0 0 0 0 0 0 0 20.0374 9.8466 0.0983 H 0 0 0 0 0 0 0 0 0 0 0 0 18.5949 10.3638 2.5474 H 0 0 0 0 0 0 0 0 0 0 0 0 17.4689 8.6952 2.1870 H 0 0 0 0 0 0 0 0 0 0 0 0 19.4802 8.5207 2.5125 H 0 0 0 0 0 0 0 0 0 0 0 0 18.5810 10.1445 -2.6170 H 0 0 0 0 0 0 0 0 0 0 0 0 17.3983 11.7944 -2.3706 H 0 0 0 0 0 0 0 0 0 0 0 0 19.4855 12.9524 -0.7258 H 0 0 0 0 0 0 0 0 0 0 0 0 20.6726 11.3565 -1.2014 H 0 0 0 0 0 0 0 0 0 0 0 0 20.0520 12.6418 -2.6660 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 1 0 0 0 0 1 6 2 0 0 0 0 1 11 1 0 0 0 0 2 3 2 0 0 0 0 2 4 1 0 0 0 0 2 37 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 5 6 1 0 0 0 0 6 8 1 0 0 0 0 7 9 1 0 0 0 0 7 8 1 0 0 0 0 7 10 2 0 0 0 0 8 17 2 0 0 0 0 9 38 1 0 0 0 0 11 12 1 0 0 0 0 11 39 1 0 0 0 0 12 16 1 0 0 0 0 12 29 2 0 0 0 0 13 14 2 0 0 0 0 13 29 1 0 0 0 0 13 40 1 0 0 0 0 14 15 1 0 0 0 0 14 31 1 0 0 0 0 15 16 2 0 0 0 0 15 41 1 0 0 0 0 16 42 1 0 0 0 0 17 18 1 0 0 0 0 17 43 1 0 0 0 0 18 21 2 0 0 0 0 18 22 1 0 0 0 0 19 22 1 0 0 0 0 19 20 2 0 0 0 0 19 24 1 0 0 0 0 20 21 1 0 0 0 0 20 44 1 0 0 0 0 21 23 1 0 0 0 0 22 45 1 0 0 0 0 23 46 1 0 0 0 0 23 47 1 0 0 0 0 23 48 1 0 0 0 0 24 25 2 0 0 0 0 24 26 1 0 0 0 0 26 27 1 0 0 0 0 26 49 1 0 0 0 0 27 28 1 0 0 0 0 27 50 1 0 0 0 0 27 51 1 0 0 0 0 28 32 1 0 0 0 0 28 52 1 0 0 0 0 28 53 1 0 0 0 0 29 30 1 0 0 0 0 32 35 1 0 0 0 0 32 33 1 0 0 0 0 33 34 1 0 0 0 0 33 54 1 0 0 0 0 33 55 1 0 0 0 0 34 56 1 0 0 0 0 34 57 1 0 0 0 0 34 58 1 0 0 0 0 35 36 1 0 0 0 0 35 59 1 0 0 0 0 35 60 1 0 0 0 0 36 61 1 0 0 0 0 36 62 1 0 0 0 0 36 63 1 0 0 0 0 M END > (643) pyrrolo[2,3-d]pyrimidin-6-one deriv. 26t > (643) PDGFR-beta > (643) 5620 > (643) -1 > (643) P > (643) PDGFR-P641 $$$$ csChFnd70/05150717532D 34 36 0 0 0 0 0 0 0 0999 V2000 1.0757 5.9136 0.0107 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7667 4.3198 -0.0236 N 0 0 0 0 0 0 0 0 0 0 0 0 1.0963 4.3970 0.0023 N 0 0 0 0 0 0 0 0 0 0 0 0 2.4811 6.7047 0.0015 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8559 5.8441 -0.0162 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5329 8.3286 0.0092 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3374 8.1197 -0.0192 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5877 8.7495 -0.0283 O 0 0 0 0 0 0 0 0 0 0 0 0 5.2536 6.5740 -0.0262 N 0 0 3 0 0 0 0 0 0 0 0 0 6.6693 5.6628 -0.0440 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9328 9.0470 -0.0008 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0259 10.7473 0.0074 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0495 11.5592 -1.3755 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1359 13.1441 -1.3597 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1994 13.9266 0.0228 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1770 13.1286 1.3975 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0837 11.5440 1.3980 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0473 10.5450 3.1248 Cl 0 0 0 0 0 0 0 0 0 0 0 0 3.9711 10.5793 -3.1116 Cl 0 0 0 0 0 0 0 0 0 0 0 0 2.4134 3.6244 -0.0144 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3690 2.0383 -0.0230 N 0 0 3 0 0 0 0 0 0 0 0 0 0.8880 1.2376 -0.0138 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 6.5328 0.0192 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4842 8.9924 0.0224 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0091 5.4424 -1.2295 H 0 0 0 0 0 0 0 0 0 0 0 0 7.5797 6.2942 0.5407 H 0 0 0 0 0 0 0 0 0 0 0 0 6.4725 4.5739 0.5433 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1542 13.7740 -2.4292 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2674 15.1660 0.0287 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2275 13.7463 2.4731 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3185 1.4542 -0.0353 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2494 1.5526 1.0169 H 0 0 0 0 0 0 0 0 0 0 0 0 0.2303 1.5642 -1.0286 H 0 0 0 0 0 0 0 0 0 0 0 0 1.0823 0.0000 -0.0226 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 23 1 0 0 0 0 2 20 2 0 0 0 0 2 5 1 0 0 0 0 3 20 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 11 2 0 0 0 0 6 24 1 0 0 0 0 7 9 1 0 0 0 0 7 11 1 0 0 0 0 7 8 2 0 0 0 0 9 10 1 0 0 0 0 10 25 1 0 0 0 0 10 26 1 0 0 0 0 10 27 1 0 0 0 0 11 12 1 0 0 0 0 12 17 1 0 0 0 0 12 13 2 0 0 0 0 13 14 1 0 0 0 0 13 19 1 0 0 0 0 14 15 2 0 0 0 0 14 28 1 0 0 0 0 15 16 1 0 0 0 0 15 29 1 0 0 0 0 16 17 2 0 0 0 0 16 30 1 0 0 0 0 17 18 1 0 0 0 0 20 21 1 0 0 0 0 21 22 1 0 0 0 0 21 31 1 0 0 0 0 22 32 1 0 0 0 0 22 33 1 0 0 0 0 22 34 1 0 0 0 0 M END > (651) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 21 > (651) PDGFR-beta > (651) 6200 > (651) -1 > (651) P > (651) PDGFR-P649 $$$$ 3-indoleacrylonitrile tyrphostin 7 csChFnd70/05150717532D 25 26 0 0 0 0 0 0 0 0999 V2000 1.8002 3.0942 0.4751 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9053 1.6981 0.6893 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1826 1.0948 0.8805 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3613 1.8790 0.8591 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2763 3.2902 0.6442 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9830 3.8981 0.4511 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6505 5.5494 0.3410 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2523 4.3171 0.5708 N 0 0 3 0 0 0 0 0 0 0 0 0 3.2438 5.3798 0.2535 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2532 6.4163 0.0206 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6532 7.6788 -0.4979 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0395 7.8838 -0.9471 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1392 8.0464 -1.3033 N 0 0 0 0 0 0 0 0 0 0 0 0 1.6573 8.8067 -0.5874 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 8.5615 -0.0504 S 0 0 0 0 0 0 0 0 0 0 0 0 2.0469 10.0360 -1.0923 N 0 0 0 0 0 0 0 0 0 0 0 0 0.8053 3.5613 0.3220 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9895 1.0716 0.7088 H 0 0 0 0 0 0 0 0 0 0 0 0 3.2537 0.0000 1.0480 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3505 1.3988 1.0093 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1870 6.5159 0.2410 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2339 4.1749 0.6705 H 0 0 0 0 0 0 0 0 0 0 0 0 1.1840 6.2231 0.2472 H 0 0 0 0 0 0 0 0 0 0 0 0 2.9860 10.1750 -1.3965 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3883 10.7820 -1.1515 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 6 1 0 0 0 0 1 17 1 0 0 0 0 2 3 1 0 0 0 0 2 18 1 0 0 0 0 3 4 2 0 0 0 0 3 19 1 0 0 0 0 4 5 1 0 0 0 0 4 20 1 0 0 0 0 5 8 1 0 0 0 0 5 6 2 0 0 0 0 6 9 1 0 0 0 0 7 8 1 0 0 0 0 7 9 2 0 0 0 0 7 21 1 0 0 0 0 8 22 1 0 0 0 0 9 10 1 0 0 0 0 10 11 2 0 0 0 0 10 23 1 0 0 0 0 11 14 1 0 0 0 0 11 12 1 0 0 0 0 12 13 3 0 0 0 0 14 16 1 0 0 0 0 14 15 2 0 0 0 0 16 24 1 0 0 0 0 16 25 1 0 0 0 0 M END > (661) Indole-Containing Inhibitor 7 > (661) PDGFR-beta > (661) 6500 > (661) -1 > (661) P > (661) PDGFR-P659 $$$$ 3-indoleacrylonitrile tyrphostin 10 csChFnd70/05150717532D 25 26 0 0 0 0 0 0 0 0999 V2000 1.3445 3.1734 0.4834 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4519 1.7416 0.7019 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7612 1.1227 0.8985 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9701 1.9267 0.8786 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8832 3.3736 0.6590 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5573 3.9972 0.4604 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2708 5.6863 0.3516 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8834 4.4275 0.5859 N 0 0 3 0 0 0 0 0 0 0 0 0 2.8276 5.5163 0.2587 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8148 6.5811 0.0207 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2283 7.8756 -0.5087 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6506 8.0835 -0.9674 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7790 8.2485 -1.3313 N 0 0 0 0 0 0 0 0 0 0 0 0 1.2087 9.0355 -0.6000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 8.8587 -0.2101 O 0 0 0 0 0 0 0 0 0 0 0 0 1.6114 10.2959 -1.1155 N 0 0 0 0 0 0 0 0 0 0 0 0 0.3245 3.6528 0.3262 H 0 0 0 0 0 0 0 0 0 0 0 0 0.5127 1.0992 0.7204 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8339 0.0000 1.0693 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9841 1.4341 1.0336 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8227 6.6765 0.2516 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8897 4.2814 0.6894 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7180 6.3850 0.2521 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5748 10.4368 -1.4263 H 0 0 0 0 0 0 0 0 0 0 0 0 0.9378 11.0622 -1.1758 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 6 1 0 0 0 0 1 17 1 0 0 0 0 2 3 1 0 0 0 0 2 18 1 0 0 0 0 3 4 2 0 0 0 0 3 19 1 0 0 0 0 4 5 1 0 0 0 0 4 20 1 0 0 0 0 5 8 1 0 0 0 0 5 6 2 0 0 0 0 6 9 1 0 0 0 0 7 8 1 0 0 0 0 7 9 2 0 0 0 0 7 21 1 0 0 0 0 8 22 1 0 0 0 0 9 10 1 0 0 0 0 10 11 2 0 0 0 0 10 23 1 0 0 0 0 11 14 1 0 0 0 0 11 12 1 0 0 0 0 12 13 3 0 0 0 0 14 16 1 0 0 0 0 14 15 2 0 0 0 0 16 24 1 0 0 0 0 16 25 1 0 0 0 0 M END > (663) Indole-Containing Inhibitor 10 > (663) PDGFR-beta > (663) 6500 > (663) -1 > (663) P > (663) PDGFR-P661 $$$$ Structure29 csChFnd70/05150717532D 46 49 0 0 0 0 0 0 0 0999 V2000 1.7361 3.2461 0.0099 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7555 1.8224 0.0021 C 0 0 0 0 0 0 0 0 0 0 0 0 3.0029 1.1160 -0.0131 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2379 1.8246 -0.0211 C 0 0 0 0 0 0 0 0 0 0 0 0 4.2402 3.2621 -0.0138 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9768 3.9754 0.0020 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7413 5.5281 -0.0065 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3339 5.4566 0.0065 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2811 4.2364 -0.0195 N 0 0 3 0 0 0 0 0 0 0 0 0 2.3648 6.6251 0.0216 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9734 7.1033 1.1167 O 0 0 0 0 0 0 0 0 0 0 0 0 5.8209 7.2419 -0.0084 Se 0 0 0 0 0 0 0 0 0 0 0 0 6.0445 7.6485 -2.4026 Se 0 0 0 0 0 0 0 0 0 0 0 0 7.1241 9.3623 -2.4045 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5315 9.4339 -2.4184 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8887 10.9151 -2.4142 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6253 11.6283 -2.3973 C 0 0 0 0 0 0 0 0 0 0 0 0 10.1293 11.6444 -2.4228 C 0 0 0 0 0 0 0 0 0 0 0 0 7.6273 13.0658 -2.3919 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8625 13.7744 -2.3928 C 0 0 0 0 0 0 0 0 0 0 0 0 10.1098 13.0681 -2.4150 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5843 10.6541 -2.3980 N 0 0 3 0 0 0 0 0 0 0 0 0 9.8912 7.7869 -3.5291 O 0 0 0 0 0 0 0 0 0 0 0 0 9.5006 8.2653 -2.4339 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9091 7.1676 -1.1776 N 0 0 3 0 0 0 0 0 0 0 0 0 0.9427 8.3328 -1.1626 C 0 0 0 0 0 0 0 0 0 0 0 0 9.9571 7.7232 -1.2349 N 0 0 3 0 0 0 0 0 0 0 0 0 10.9235 6.5580 -1.2503 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7637 3.7938 0.0175 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7951 1.2538 0.0082 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0060 0.0000 -0.0184 H 0 0 0 0 0 0 0 0 0 0 0 0 5.2033 1.2645 -0.0327 H 0 0 0 0 0 0 0 0 0 0 0 0 6.2612 4.0262 -0.0298 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1017 11.0968 -2.4353 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6620 13.6259 -2.3874 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8593 14.8905 -2.3890 H 0 0 0 0 0 0 0 0 0 0 0 0 11.0702 13.6368 -2.4214 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6042 10.8643 -2.3918 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2211 6.7863 -2.0506 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 8.0318 -0.6245 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4158 9.2061 -0.6312 H 0 0 0 0 0 0 0 0 0 0 0 0 0.6932 8.6274 -2.2208 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6457 8.1046 -0.3617 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1737 6.2635 -0.1922 H 0 0 0 0 0 0 0 0 0 0 0 0 10.4501 5.6845 -1.7811 H 0 0 0 0 0 0 0 0 0 0 0 0 11.8659 6.8588 -1.7892 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 1 6 1 0 0 0 0 1 29 1 0 0 0 0 2 3 1 0 0 0 0 2 30 1 0 0 0 0 3 4 2 0 0 0 0 3 31 1 0 0 0 0 4 5 1 0 0 0 0 4 32 1 0 0 0 0 5 9 1 0 0 0 0 5 6 2 0 0 0 0 6 8 1 0 0 0 0 7 9 1 0 0 0 0 7 8 2 0 0 0 0 7 12 1 0 0 0 0 8 10 1 0 0 0 0 9 33 1 0 0 0 0 10 11 2 0 0 0 0 10 25 1 0 0 0 0 12 13 1 0 0 0 0 13 14 1 0 0 0 0 14 15 2 0 0 0 0 14 22 1 0 0 0 0 15 16 1 0 0 0 0 15 24 1 0 0 0 0 16 18 2 0 0 0 0 16 17 1 0 0 0 0 17 22 1 0 0 0 0 17 19 2 0 0 0 0 18 21 1 0 0 0 0 18 34 1 0 0 0 0 19 20 1 0 0 0 0 19 35 1 0 0 0 0 20 21 2 0 0 0 0 20 36 1 0 0 0 0 21 37 1 0 0 0 0 22 38 1 0 0 0 0 23 24 2 0 0 0 0 24 27 1 0 0 0 0 25 26 1 0 0 0 0 25 39 1 0 0 0 0 26 40 1 0 0 0 0 26 41 1 0 0 0 0 26 42 1 0 0 0 0 27 28 1 0 0 0 0 27 43 1 0 0 0 0 28 44 1 0 0 0 0 28 45 1 0 0 0 0 28 46 1 0 0 0 0 M END > (689) diselenobis(1H-indole) deriv. 25 > (689) PDGFR-beta > (689) 8000 > (689) -1 > (689) P > (689) PDGFR-P687 $$$$ 5-indoleacrylonitrile tyrphostin 4 csChFnd70/05150717532D 35 37 0 0 0 0 0 0 0 0999 V2000 1.4389 2.1578 0.7871 N 0 0 3 0 0 0 0 0 0 0 0 0 1.1179 3.4675 1.5653 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3968 4.2717 1.7824 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6392 3.4045 1.0854 C 0 0 0 0 0 0 0 0 0 0 0 0 2.9679 2.0823 0.4756 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1973 3.6413 0.9413 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8722 1.0141 -0.2725 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3971 1.2438 -0.4152 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0836 2.5576 0.1883 C 0 0 0 0 0 0 0 0 0 0 0 0 7.7251 2.7899 0.0263 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3064 4.2441 -0.0633 C 0 0 0 0 0 0 0 0 0 0 0 0 7.2982 5.5190 -0.1712 C 0 0 0 0 0 0 0 0 0 0 0 0 6.4985 6.5303 -0.2568 N 0 0 0 0 0 0 0 0 0 0 0 0 9.9612 4.4856 -0.0482 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8145 3.4177 0.1700 O 0 0 0 0 0 0 0 0 0 0 0 0 10.5875 6.0232 -0.2977 C 0 0 0 0 0 0 0 0 0 0 0 0 11.9790 6.4321 0.3539 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7936 7.0714 -1.1914 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3798 8.5062 -1.4231 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7590 8.9147 -0.7704 C 0 0 0 0 0 0 0 0 0 0 0 0 12.5601 7.8724 0.1170 C 0 0 0 0 0 0 0 0 0 0 0 0 13.9138 8.2740 0.7489 O 0 0 0 0 0 0 0 0 0 0 0 0 12.3322 10.3302 -1.0027 O 0 0 0 0 0 0 0 0 0 0 0 0 0.6965 1.3931 0.5018 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 3.8043 1.9475 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4926 5.3518 2.3601 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7165 4.6529 1.4063 H 0 0 0 0 0 0 0 0 0 0 0 0 3.3603 0.0000 -0.7403 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0864 0.4095 -0.9965 H 0 0 0 0 0 0 0 0 0 0 0 0 8.4805 1.8224 -0.0230 H 0 0 0 0 0 0 0 0 0 0 0 0 12.5981 5.6240 1.0414 H 0 0 0 0 0 0 0 0 0 0 0 0 8.7209 6.7566 -1.7007 H 0 0 0 0 0 0 0 0 0 0 0 0 9.7654 9.3150 -2.1141 H 0 0 0 0 0 0 0 0 0 0 0 0 14.7853 8.0617 0.1121 H 0 0 0 0 0 0 0 0 0 0 0 0 12.0140 11.0701 -0.2534 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 5 1 0 0 0 0 1 24 1 0 0 0 0 2 3 2 0 0 0 0 2 25 1 0 0 0 0 3 4 1 0 0 0 0 3 26 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 7 1 0 0 0 0 6 9 2 0 0 0 0 6 27 1 0 0 0 0 7 8 2 0 0 0 0 7 28 1 0 0 0 0 8 9 1 0 0 0 0 8 29 1 0 0 0 0 9 10 1 0 0 0 0 10 11 2 0 0 0 0 10 30 1 0 0 0 0 11 14 1 0 0 0 0 11 12 1 0 0 0 0 12 13 3 0 0 0 0 14 15 2 0 0 0 0 14 16 1 0 0 0 0 16 17 2 0 0 0 0 16 18 1 0 0 0 0 17 21 1 0 0 0 0 17 31 1 0 0 0 0 18 19 2 0 0 0 0 18 32 1 0 0 0 0 19 20 1 0 0 0 0 19 33 1 0 0 0 0 20 21 2 0 0 0 0 20 23 1 0 0 0 0 21 22 1 0 0 0 0 22 34 1 0 0 0 0 23 35 1 0 0 0 0 M END > (717) Indole-Containing Inhibitor 4 > (717) PDGFR-beta > (717) 10000 > (717) -1 > (717) P > (717) PDGFR-P715 $$$$ quinoline deriv. 21 csChFnd70/05150717532D 23 24 0 0 0 0 0 0 0 0999 V2000 2.2777 3.2695 -0.1348 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8314 1.8377 -0.2247 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5312 4.0269 -0.1034 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8312 3.3101 -0.1488 C 0 0 0 0 0 0 0 0 0 0 0 0 6.0292 4.0345 -0.1196 N 0 0 0 0 0 0 0 0 0 0 0 0 6.0613 5.4050 -0.0496 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8534 6.2173 0.0006 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5916 1.1307 -0.2536 C 0 0 0 0 0 0 0 0 0 0 0 0 2.3175 1.8415 -0.2092 C 0 0 0 0 0 0 0 0 0 0 0 0 3.5440 5.5616 -0.0242 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2402 6.3726 0.0266 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1946 7.6107 0.7447 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3706 8.0423 1.5722 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3035 8.3846 2.2287 N 0 0 0 0 0 0 0 0 0 0 0 0 0.9708 8.4772 0.6701 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 9.1645 0.6109 N 0 0 0 0 0 0 0 0 0 0 0 0 1.2839 3.8106 -0.0957 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8106 1.2703 -0.2603 H 0 0 0 0 0 0 0 0 0 0 0 0 7.0671 5.9248 -0.0297 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9260 7.3458 0.0588 H 0 0 0 0 0 0 0 0 0 0 0 0 3.5967 0.0000 -0.3124 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3488 1.2556 -0.2336 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3153 5.9913 -0.5037 H 0 0 0 0 0 0 0 0 0 0 0 0 1 9 1 0 0 0 0 1 3 2 0 0 0 0 1 17 1 0 0 0 0 2 8 1 0 0 0 0 2 4 2 0 0 0 0 2 18 1 0 0 0 0 3 10 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 6 7 1 0 0 0 0 6 19 1 0 0 0 0 7 10 2 0 0 0 0 7 20 1 0 0 0 0 8 9 2 0 0 0 0 8 21 1 0 0 0 0 9 22 1 0 0 0 0 10 11 1 0 0 0 0 11 12 2 0 0 0 0 11 23 1 0 0 0 0 12 13 1 0 0 0 0 12 15 1 0 0 0 0 13 14 3 0 0 0 0 15 16 3 0 0 0 0 M END > (718) Quinoline-Containing Inhibitor 21 > (718) PDGFR-beta > (718) 10000 > (718) -1 > (718) P > (718) PDGFR-P716 $$$$ csChFnd70/05150717532D 33 34 0 0 0 0 0 0 0 0999 V2000 10.9407 4.3918 -0.2978 C 0 0 0 0 0 0 0 0 0 0 0 0 12.2250 5.0241 -1.0585 C 0 0 0 0 0 0 0 0 0 0 0 0 11.0939 3.0003 0.5195 C 0 0 0 0 0 0 0 0 0 0 0 0 13.6292 4.2782 -1.0006 C 0 0 0 0 0 0 0 0 0 0 0 0 12.5069 2.2620 0.5701 C 0 0 0 0 0 0 0 0 0 0 0 0 13.7786 2.8991 -0.1905 C 0 0 0 0 0 0 0 0 0 0 0 0 12.6602 0.9127 1.3620 O 0 0 0 0 0 0 0 0 0 0 0 0 15.1670 2.1693 -0.1386 O 0 0 0 0 0 0 0 0 0 0 0 0 9.4466 5.1855 -0.3509 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0952 4.3455 -0.2757 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6015 5.1475 -0.1454 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1451 2.6915 -0.3241 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1847 1.3794 -0.3626 N 0 0 0 0 0 0 0 0 0 0 0 0 6.5591 6.5526 -0.1043 O 0 0 0 0 0 0 0 0 0 0 0 0 5.2799 4.3258 -0.0718 N 0 0 3 0 0 0 0 0 0 0 0 0 3.8723 5.0798 0.1802 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0871 6.5710 0.6798 C 0 0 0 0 0 0 0 0 0 0 0 0 1.1374 5.2608 -0.2347 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4247 7.1341 1.3501 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5257 4.5137 -0.4863 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8167 6.3925 1.1030 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1123 6.0953 -1.6897 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1089 2.5081 1.1079 H 0 0 0 0 0 0 0 0 0 0 0 0 14.6177 4.7660 -1.5868 H 0 0 0 0 0 0 0 0 0 0 0 0 12.4618 0.0000 0.7478 H 0 0 0 0 0 0 0 0 0 0 0 0 15.8120 2.4797 0.7200 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4036 6.4294 -0.4492 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3050 3.2113 -0.1936 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 7.1533 0.8744 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0906 4.8237 -0.7561 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3815 8.1576 2.0637 H 0 0 0 0 0 0 0 0 0 0 0 0 2.5643 3.4907 -1.2010 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8608 6.8326 1.6272 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 3 2 0 0 0 0 1 9 1 0 0 0 0 2 4 2 0 0 0 0 2 22 1 0 0 0 0 3 5 1 0 0 0 0 3 23 1 0 0 0 0 4 6 1 0 0 0 0 4 24 1 0 0 0 0 5 6 2 0 0 0 0 5 7 1 0 0 0 0 6 8 1 0 0 0 0 7 25 1 0 0 0 0 8 26 1 0 0 0 0 9 10 2 0 0 0 0 9 27 1 0 0 0 0 10 11 1 0 0 0 0 10 12 1 0 0 0 0 11 14 2 0 0 0 0 11 15 1 0 0 0 0 12 13 3 0 0 0 0 15 16 1 0 0 0 0 15 28 1 0 0 0 0 16 20 1 0 0 0 0 16 21 2 0 0 0 0 17 18 1 0 0 0 0 17 19 2 0 0 0 0 17 29 1 0 0 0 0 18 20 2 0 0 0 0 18 30 1 0 0 0 0 19 21 1 0 0 0 0 19 31 1 0 0 0 0 20 32 1 0 0 0 0 21 33 1 0 0 0 0 M END > (719) tyrphostin 1 > (719) PDGFR-beta > (719) 10000 > (719) -1 > (719) P > (719) PDGFR-P717 $$$$ csChFnd70/05150717532D 40 43 0 0 0 0 0 0 0 0999 V2000 3.8089 8.3057 0.0325 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6737 6.6058 0.0039 N 0 0 0 0 0 0 0 0 0 0 0 0 3.8295 6.6906 0.0116 N 0 0 0 0 0 0 0 0 0 0 0 0 5.3064 9.1470 0.0399 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7701 8.2291 0.0246 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3632 10.8763 0.0614 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3501 10.6513 0.0532 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6824 11.3208 0.0596 O 0 0 0 0 0 0 0 0 0 0 0 0 8.2594 9.0051 0.0317 N 0 0 3 0 0 0 0 0 0 0 0 0 6.8549 11.6402 0.0673 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9555 13.4508 0.0891 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9926 14.3256 -1.3775 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0859 16.0135 -1.3484 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1433 16.8368 0.1301 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1076 15.9768 1.5884 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0067 14.2892 1.5765 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9532 13.2127 3.4080 Cl 0 0 0 0 0 0 0 0 0 0 0 0 6.9221 13.2948 -3.2343 Cl 0 0 0 0 0 0 0 0 0 0 0 0 5.2316 5.8667 -0.0023 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1829 4.1754 -0.0246 N 0 0 3 0 0 0 0 0 0 0 0 0 9.7665 8.0335 0.0161 C 0 0 0 0 0 0 0 0 0 0 0 0 3.6890 3.3632 0.1136 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9140 1.1322 -0.5467 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4091 1.8977 -0.7157 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4379 3.9914 1.0902 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9777 3.1503 1.1941 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7577 1.7697 0.3845 N 0 0 0 0 0 0 0 0 0 0 0 0 2.6636 8.9661 0.0383 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2467 11.5843 0.0728 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1147 16.6921 -2.4827 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2166 18.1566 0.1460 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1537 16.6268 2.7386 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1884 3.5538 -0.1364 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1379 7.8086 -1.2455 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7320 8.6998 0.6519 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5512 6.8689 0.6306 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6841 0.0000 -1.1892 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3498 1.3698 -1.4799 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6100 5.1203 1.7561 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 3.6304 1.9432 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 28 1 0 0 0 0 2 19 2 0 0 0 0 2 5 1 0 0 0 0 3 19 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 10 2 0 0 0 0 6 29 1 0 0 0 0 7 9 1 0 0 0 0 7 10 1 0 0 0 0 7 8 2 0 0 0 0 9 21 1 0 0 0 0 10 11 1 0 0 0 0 11 16 1 0 0 0 0 11 12 2 0 0 0 0 12 13 1 0 0 0 0 12 18 1 0 0 0 0 13 14 2 0 0 0 0 13 30 1 0 0 0 0 14 15 1 0 0 0 0 14 31 1 0 0 0 0 15 16 2 0 0 0 0 15 32 1 0 0 0 0 16 17 1 0 0 0 0 19 20 1 0 0 0 0 20 22 1 0 0 0 0 20 33 1 0 0 0 0 21 34 1 0 0 0 0 21 35 1 0 0 0 0 21 36 1 0 0 0 0 22 24 1 0 0 0 0 22 25 2 0 0 0 0 23 27 1 0 0 0 0 23 24 2 0 0 0 0 23 37 1 0 0 0 0 24 38 1 0 0 0 0 25 26 1 0 0 0 0 25 39 1 0 0 0 0 26 27 2 0 0 0 0 26 40 1 0 0 0 0 M END > (89) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 42 > (89) PDGFR-beta > (89) 100 > (89) -1 > (89) P > (89) PDGFR-P87 $$$$ Indolin-2-one deriv. 9c csChFnd70/05150717532D 50 53 0 0 0 0 0 0 0 0999 V2000 5.7772 4.2530 -0.1495 C 0 0 0 0 0 0 0 0 0 0 0 0 5.7501 2.6642 -0.3918 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9528 1.9476 -1.1918 C 0 0 0 0 0 0 0 0 0 0 0 0 8.1884 2.8075 -1.7555 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2366 4.4088 -1.5231 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0168 5.1300 -0.7126 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3970 6.8096 -0.6576 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8877 6.9555 -1.4828 C 0 0 0 0 0 0 0 0 0 0 0 0 9.3205 5.5285 -1.9571 N 0 0 3 0 0 0 0 0 0 0 0 0 9.6064 8.1593 -1.6986 O 0 0 0 0 0 0 0 0 0 0 0 0 6.5361 7.9862 0.0228 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1593 9.5014 0.1331 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3294 10.8855 0.0433 C 0 0 0 0 0 0 0 0 0 0 0 0 8.7049 9.8792 0.3570 N 0 0 3 0 0 0 0 0 0 0 0 0 4.5980 11.0519 -0.1891 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7861 11.0800 1.3964 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0547 11.2464 1.1639 C 0 0 0 0 0 0 0 0 0 0 0 0 1.5247 11.3336 -0.1363 O 0 0 0 0 0 0 0 0 0 0 0 0 1.1015 11.2978 2.4016 O 0 0 0 0 0 0 0 0 0 0 0 0 8.8374 11.4483 0.3973 C 0 0 0 0 0 0 0 0 0 0 0 0 7.3994 12.0890 0.2090 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0813 13.8166 0.1980 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3076 12.3889 0.6139 C 0 0 0 0 0 0 0 0 0 0 0 0 9.9839 14.0674 0.0991 C 0 0 0 0 0 0 0 0 0 0 0 0 8.4981 14.6546 0.8901 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7488 0.0000 0.4823 O 0 0 0 0 0 0 0 0 0 0 0 0 3.5248 2.4064 1.5693 O 0 0 0 0 0 0 0 0 0 0 0 0 4.1831 1.5462 0.3185 S 0 0 0 0 0 0 0 0 0 0 0 0 2.8452 1.4924 -1.0690 N 0 0 0 0 0 0 0 0 0 0 0 0 4.8373 4.8133 0.4702 H 0 0 0 0 0 0 0 0 0 0 0 0 6.9241 0.7040 -1.3762 H 0 0 0 0 0 0 0 0 0 0 0 0 9.1194 2.2352 -2.3776 H 0 0 0 0 0 0 0 0 0 0 0 0 10.2679 5.3087 -2.5316 H 0 0 0 0 0 0 0 0 0 0 0 0 5.3856 7.7454 0.4703 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5542 9.1430 0.4675 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3562 12.1335 -0.8075 H 0 0 0 0 0 0 0 0 0 0 0 0 4.1662 10.0705 -0.8683 H 0 0 0 0 0 0 0 0 0 0 0 0 4.0279 9.9983 2.0148 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2180 12.0613 2.0756 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 11.4054 2.1943 H 0 0 0 0 0 0 0 0 0 0 0 0 6.8930 14.2088 -0.9944 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0526 14.0663 0.8982 H 0 0 0 0 0 0 0 0 0 0 0 0 10.6476 12.3750 1.8366 H 0 0 0 0 0 0 0 0 0 0 0 0 11.2383 11.8964 -0.0948 H 0 0 0 0 0 0 0 0 0 0 0 0 10.9596 14.8075 0.4322 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8379 14.1024 -1.1613 H 0 0 0 0 0 0 0 0 0 0 0 0 8.3832 15.9047 0.7031 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5634 14.4172 2.1352 H 0 0 0 0 0 0 0 0 0 0 0 0 3.0251 2.0261 -2.0481 H 0 0 0 0 0 0 0 0 0 0 0 0 1.8817 0.9271 -0.9028 H 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 1 6 2 0 0 0 0 1 30 1 0 0 0 0 2 3 2 0 0 0 0 2 28 1 0 0 0 0 3 4 1 0 0 0 0 3 31 1 0 0 0 0 4 5 2 0 0 0 0 4 32 1 0 0 0 0 5 9 1 0 0 0 0 5 6 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 7 11 2 0 0 0 0 8 9 1 0 0 0 0 8 10 2 0 0 0 0 9 33 1 0 0 0 0 11 12 1 0 0 0 0 11 34 1 0 0 0 0 12 13 2 0 0 0 0 12 14 1 0 0 0 0 13 21 1 0 0 0 0 13 15 1 0 0 0 0 14 20 1 0 0 0 0 14 35 1 0 0 0 0 15 16 1 0 0 0 0 15 36 1 0 0 0 0 15 37 1 0 0 0 0 16 17 1 0 0 0 0 16 38 1 0 0 0 0 16 39 1 0 0 0 0 17 19 1 0 0 0 0 17 18 2 0 0 0 0 19 40 1 0 0 0 0 20 23 1 0 0 0 0 20 21 2 0 0 0 0 21 22 1 0 0 0 0 22 25 1 0 0 0 0 22 41 1 0 0 0 0 22 42 1 0 0 0 0 23 24 1 0 0 0 0 23 43 1 0 0 0 0 23 44 1 0 0 0 0 24 25 1 0 0 0 0 24 45 1 0 0 0 0 24 46 1 0 0 0 0 25 47 1 0 0 0 0 25 48 1 0 0 0 0 26 28 2 0 0 0 0 27 28 2 0 0 0 0 28 29 1 0 0 0 0 29 49 1 0 0 0 0 29 50 1 0 0 0 0 M END > (892) Indolin-2-one deriv. 9c > (892) PDGFR-beta > (892) <780 > (892) -1 > (892) P > (892) PDGFR-P890 $$$$ csChFnd70/05150717532D 43 46 0 0 0 0 0 0 0 0999 V2000 3.8142 8.3173 0.0326 C 0 0 0 0 0 0 0 0 0 0 0 0 6.6830 6.6150 0.0039 N 0 0 0 0 0 0 0 0 0 0 0 0 3.8349 6.7000 0.0116 N 0 0 0 0 0 0 0 0 0 0 0 0 5.3138 9.1598 0.0399 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7795 8.2405 0.0246 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3707 10.8914 0.0615 C 0 0 0 0 0 0 0 0 0 0 0 0 8.3618 10.6661 0.0533 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6959 11.3365 0.0597 O 0 0 0 0 0 0 0 0 0 0 0 0 8.2709 9.0177 0.0317 N 0 0 3 0 0 0 0 0 0 0 0 0 6.8644 11.6564 0.0674 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9652 13.4695 0.0892 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0023 14.3456 -1.3794 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0957 16.0358 -1.3503 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1532 16.8602 0.1303 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1174 15.9991 1.5906 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0164 14.3091 1.5787 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9629 13.2311 3.4127 Cl 0 0 0 0 0 0 0 0 0 0 0 0 6.9317 13.3134 -3.2388 Cl 0 0 0 0 0 0 0 0 0 0 0 0 5.2389 5.8749 -0.0023 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1901 4.1812 -0.0246 N 0 0 3 0 0 0 0 0 0 0 0 0 3.6942 3.3679 0.1137 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9167 1.1337 -0.5474 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4138 1.9004 -0.7167 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4413 3.9970 1.0917 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9790 3.1547 1.1958 C 0 0 0 0 0 0 0 0 0 0 0 0 0.7588 1.7721 0.3850 N 0 0 0 0 0 0 0 0 0 0 0 0 9.7801 8.0446 0.0162 C 0 0 0 0 0 0 0 0 0 0 0 0 10.3021 7.7286 -1.7572 C 0 0 0 0 0 0 0 0 0 0 0 0 2.6673 8.9786 0.0384 H 0 0 0 0 0 0 0 0 0 0 0 0 4.2526 11.6004 0.0729 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1246 16.7153 -2.4862 H 0 0 0 0 0 0 0 0 0 0 0 0 7.2267 18.1818 0.1462 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1636 16.6500 2.7425 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1970 3.5587 -0.1365 H 0 0 0 0 0 0 0 0 0 0 0 0 1.6864 0.0000 -1.1909 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3558 1.3717 -1.4820 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6136 5.1274 1.7585 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 3.6355 1.9459 H 0 0 0 0 0 0 0 0 0 0 0 0 10.7469 8.7120 0.6528 H 0 0 0 0 0 0 0 0 0 0 0 0 9.5645 6.8784 0.6315 H 0 0 0 0 0 0 0 0 0 0 0 0 9.3354 7.0612 -2.3939 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5178 8.8949 -2.3725 H 0 0 0 0 0 0 0 0 0 0 0 0 11.4250 7.0046 -1.7687 H 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 4 1 0 0 0 0 1 29 1 0 0 0 0 2 19 2 0 0 0 0 2 5 1 0 0 0 0 3 19 1 0 0 0 0 4 6 1 0 0 0 0 4 5 2 0 0 0 0 5 9 1 0 0 0 0 6 10 2 0 0 0 0 6 30 1 0 0 0 0 7 9 1 0 0 0 0 7 10 1 0 0 0 0 7 8 2 0 0 0 0 9 27 1 0 0 0 0 10 11 1 0 0 0 0 11 16 1 0 0 0 0 11 12 2 0 0 0 0 12 13 1 0 0 0 0 12 18 1 0 0 0 0 13 14 2 0 0 0 0 13 31 1 0 0 0 0 14 15 1 0 0 0 0 14 32 1 0 0 0 0 15 16 2 0 0 0 0 15 33 1 0 0 0 0 16 17 1 0 0 0 0 19 20 1 0 0 0 0 20 21 1 0 0 0 0 20 34 1 0 0 0 0 21 23 1 0 0 0 0 21 24 2 0 0 0 0 22 26 1 0 0 0 0 22 23 2 0 0 0 0 22 35 1 0 0 0 0 23 36 1 0 0 0 0 24 25 1 0 0 0 0 24 37 1 0 0 0 0 25 26 2 0 0 0 0 25 38 1 0 0 0 0 27 28 1 0 0 0 0 27 39 1 0 0 0 0 27 40 1 0 0 0 0 28 41 1 0 0 0 0 28 42 1 0 0 0 0 28 43 1 0 0 0 0 M END > (93) 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 43 > (93) PDGFR-beta > (93) 100 > (93) -1 > (93) P > (93) PDGFR-P91 $$$$