TTD | Expression Details

Target General Information
Target ID	T30985
Target Name	Histamine H2 receptor
Synonyms	Gastric receptor I; H2R; Histamine receptor 2; HRH2
Target Type	Successful
Gene Name	HRH2
Biochemical Class	GPCR rhodopsin
UniProt ID	HRH2_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Ulcerative colitis
Example drug	Pibutidine			Discontinued in Phase 3	[544697], [1572592]
Tissue	Colon mucosal tissue
Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section	Fold-change: 0.19 Z-score: 0.36 P-value: 2.78E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of the persons with other diseases not directly affecting the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of the persons with other diseases not directly affecting the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 544697	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000641)
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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