Target General Information
Target ID	T72168
Target Name	Mineralocorticoid receptor
Synonyms	Delta; Inner ear mineralocorticoid receptor; MR; NR3C2
Target Type	Successful
Gene Name	NR3C2
Biochemical Class	Zinc-finger
UniProt ID	MCR_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Type 2 diabetes
Example drug	XL550			Phase 1	[550638], [1572592]
Tissue	Liver tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -5.31E-04 Z-score: -1.53E-03 P-value: 7.31E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 550638	Clinical pipeline report, company report or official report of Exelixis (2011).
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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