Target Information
| Target General Infomation | |||||
|---|---|---|---|---|---|
| Target ID |
T75476
|
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| Former ID |
TTDR01108
|
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| Target Name |
Myeloid differentiation primary response protein MyD88
|
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| Gene Name |
MYD88
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| Synonyms |
MyD88; MYD88
|
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| Target Type |
Research
|
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| Function |
Adapter protein involved in the toll-like receptor and il-1 receptor signaling pathway in the innate immune response. Acts via irak1, irak2 and traf6, leading to nf-kappa-b activation, cytokine secretion and the inflammatory response.
|
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| UniProt ID | |||||
| Sequence |
MAAGGPGAGSAAPVSSTSSLPLAALNMRVRRRLSLFLNVRTQVAADWTALAEEMDFEYLE
IRQLETQADPTGRLLDAWQGRPGASVGRLLELLTKLGRDDVLLELGPSIEEDCQKYILKQ QQEEAEKPLQVAAVDSSVPRTAELAGITTLDDPLGHMPERFDAFICYCPSDIQFVQEMIR QLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRCRRMVVVVSDDYLQSKECDFQTKFA LSLSPGAHQKRLIPIKYKAMKKEFPSILRFITVCDYTNPCTKSWFWTRLAKALSLP |
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| Target Expression Profile (TEP) and Drug Resistance Mutation (DRM) | |||||
| DRM | DRM Info | ||||
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