Target General Infomation
Target ID
T53489
Former ID
TTDR01230
Target Name
Cytochrome B
Gene Name
MT-CYB
Synonyms
Cyb; MT-CYB
Target Type
Research
Function
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
BioChemical Class
Cytochrome b family
UniProt ID
Sequence
MNFYSINLVKAHLINYPCPLNINFLWNYGFLLGIIFFIQIITGVFLASRYTPDVSYAYYS
IQHILRELWSGWCFRYMHATGASLVFLLTYLHILRGLNYSYMYLPLSWISGLILFMIFIV
TAFVGYVLPWGQMSYWGATVITNLLSSIPVAVIWICGGYTVSDPTIKRFFVLHFILPFIG
LCIVFIHIFFLHLHGSTNPLGYDTALKIPFYPNLLSLDVKGFNNVIILFLIQSLFGIIPL
SHPDNAIVVNTYVTPSQIVPEWYFLPFYAMLKTVPSKPAGLVIVLLSLQLLFLLAEQRSL
TTIIQFKMIFGARDYSVPIIWFMCAFYALLWIGCQLPQDIFILYGRLFIVLFFCSGLFVL
VHYRRTHYDYSSQANI
Inhibitor 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE Drug Info [551374]
5-HEPTYL-6-HYDROXY-1,3-BENZOTHIAZOLE-4,7-DIONE Drug Info [551374]
5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole Drug Info [551374]
B-2-Octylglucoside Drug Info [551393]
B-Octylglucoside Drug Info [551393]
FAMOXADONE Drug Info [551374]
UBIQUINONE-2 Drug Info [551374]
Target Expression Profile (TEP) and Drug Resistance Mutation (DRM)
DRM DRM Info
Pathways
KEGG Pathway Oxidative phosphorylation
Metabolic pathways
References
Ref 551374The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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