Target Information

Target General Infomation
Target ID
T62704
Former ID
TTDS00423
Target Name
3-beta-HSD
Synonyms
3-beta-HSD; 3-beta-hydroxy-5-ene steroid dehydrogenase; 3-beta-hydroxy-Delta(5)-steroid dehydrogenase; 3BH; Delta-5-3-ketosteroid isomerase; HSD3B1; HSDB3A; Progesterone reductase; Steroid Delta-isomerase; Trophoblast antigen FDO161G
Target Type
Research
Disease Termination of early pregnancy [ICD9: 779.6; ICD10: O04]
BioChemical Class
Short-chain dehydrogenases reductases
EC Number
EC 5.3.3.1
Inhibitor 3-Beta-Hydroxy-5-Androsten-17-One Drug Info [551393]
4-MA Drug Info [538047]
5alpha-Androstan-3,17-Dione Drug Info [551393]
Beta-Mercaptoethanol Drug Info [551393]
Epostane Drug Info [537738]
Equilenin Drug Info [551393]
Agonist 4-Androstenedione Drug Info [551393]
References
Ref 537738Termination of early pregnancy by the 3 beta-hydroxysteroid dehydrogenase inhibitor epostane. N Engl J Med. 1988 Sep 29;319(13):813-7.
Ref 538047Activity and inhibition of 3-beta-hydroxysteroid dehydrogenase/delta-5-4-isomerase in human skin. Skin Pharmacol. 1997;10(3):160-8.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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