Target General Infomation
Target ID
T76181
Former ID
TTDI03227
Target Name
Glycine Receptor (All subtypes)
Target Type
Research
Agonist taurine Drug Info [534309]
Antagonist [3H]strychnine Drug Info [526747]
References
Ref 525799Subunit-specific action of an anticonvulsant thiobutyrolactone on recombinant glycine receptors involves a residue in the M2 membrane-spanning region. Mol Pharmacol. 2000 Jul;58(1):11-7.
Ref 526747Distinct agonist- and antagonist-binding sites on the glycine receptor. Neuron. 1992 Sep;9(3):491-6.
Ref 527446Developmental regulation of beta-carboline-induced inhibition of glycine-evoked responses depends on glycine receptor beta subunit expression. Mol Pharmacol. 2005 May;67(5):1783-96. Epub 2005 Feb 18.
Ref 528279Molecular determinants of ginkgolide binding in the glycine receptor pore. J Neurochem. 2006 Jul;98(2):395-407.
Ref 529364Subunit-specific potentiation of recombinant glycine receptors by NV-31, a bilobalide-derived compound. Neurosci Lett. 2008 Apr 18;435(2):147-51.
Ref 533882Cyanotriphenylborate: subtype-specific blocker of glycine receptor chloride channels. Proc Natl Acad Sci U S A. 1994 Sep 13;91(19):8950-4.
Ref 534309Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel. EMBO J. 1997 Jan 2;16(1):110-20.
Ref 534540Selective actions of a detergent on ligand-gated ion channels expressed in Xenopus oocytes. J Pharmacol Exp Ther. 1998 Jan;284(1):32-6.

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