Target General Infomation
Target ID
T79589
Former ID
TTDR00304
Target Name
Enoyl-[acyl-carrier-protein] reductase [NADH] 2
Gene Name
fabI2
Synonyms
Enoyl-ACP reductase II; NADH-dependent enoyl-ACP reductase 2; fabI2
Target Type
Research
BioChemical Class
Oxidoreductases acting on CH-CH group of donors
UniProt ID
EC Number
EC 1.3.1.9
Sequence
MNGLMNGKRGLIMGVANSHSIAWGIAKSLAAQGAELAFTYQGEALGKRVKPLAAEVNSDF
LLPCDVEDIGSVDAVVDAIKERWGKLDFVVHAIGFSDKNELKGLYADTTRDNFSRTMVIS
CFSFTEIAKRAAELMSEGGTMLTLTYGGSMRVMPNYNVMGVAKAALEASVRYLAADYGSR
GIRVNAISAGPIRTLAGAGISDARAMLSWQQKNSPLRRTVTIEDVGSSALYLLSDLSRGV
TGEIHYVDSGYNITSMPTLEALRVADAD
Inhibitor Diazaborines Drug Info [535276]
Pathways
KEGG Pathway Fatty acid biosynthesis
Biotin metabolism
Metabolic pathways
Fatty acid metabolism
References
Ref 535276Lipid biosynthesis as a target for antibacterial agents. Prog Lipid Res. 2001 Nov;40(6):467-97.

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