Drug Information

Drug General Information
Drug ID
D00OCB
Former ID
DPR000130
Drug Name
CCT-018159
Synonyms
CCT 018159; CCT018159; (6Z)-6-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methyl-1,2-dihydropyrazol-3-ylidene]-4-ethyl-3-hydroxycyclohexa-2,4-dien-1-one; 4-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]-6-ethylbenzene-1,3-diol
Drug Type
Small molecular drug
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Preclinical [547699]
Therapeutic Class
Anticancer Agents
Company
Vernalis; Novartis
Structure
Download
2D MOL

3D MOL
Formula
C20H20N2O4
Canonical SMILES
CCC1=CC(=C2C(=C(NN2)C)C3=CC4=C(C=C3)OCCO4)C(=O)C=C1O
InChI
1S/C20H20N2O4/c1-3-12-8-14(16(24)10-15(12)23)20-19(11(2)21-22-20)13-4-5-17-18(9-13)26-7-6-25-17/h4-5,8-10,21-23H,3,6-7H2,1-2H3/b20-14-
InChIKey
BBTMGPQSLSYPHE-ZHZULCJRSA-N
PubChem Compound ID
5327091
PubChem Substance ID
14876300, 26755036, 39299807, 46515661, 57361269, 80303921, 85788198, 87226551, 87920532, 99444065, 103556464, 106711248, 113905887, 117423584, 118403413, 121326964, 134964461, 137184519, 143967570, 160968665, 162023419, 163685840, 163819161, 164339467, 172649497, 198967376, 223442543, 252156511
Target and Pathway
Target(s) Heat shock protein HSP90 Target Info Inhibitor [536886]
References
Ref 547699Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018517)
Ref 536886Recent advances in Hsp90 inhibitors as antitumor agents. Anticancer Agents Med Chem. 2008 Oct;8(7):761-82.

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