Drug General Information
Drug ID
D01BIT
Former ID
DNC006696
Drug Name
N-(3-phenoxycinnamyl)-N-hydroxyacetamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529646]
Structure
Download
2D MOL

3D MOL

Formula
C17H17NO3
Canonical SMILES
CC(=O)N(CC=CC1=CC(=CC=C1)OC2=CC=CC=C2)O
InChI
1S/C17H17NO3/c1-14(19)18(20)12-6-8-15-7-5-11-17(13-15)21-16-9-3-2-4-10-16/h2-11,13,20H,12H2,1H3/b8-6+
InChIKey
CEUDWZXMLMKPNN-SOFGYWHQSA-N
PubChem Compound ID
Target and Pathway
Target(s) mRNA of human 5-lipoxygenase Target Info Inhibitor [529646]
BioCyc Pathway Aspirin-triggered lipoxin biosynthesis
Resolvin D biosynthesis
Leukotriene biosynthesis
Lipoxin biosynthesis
Aspirin triggered resolvin D biosynthesis
Aspirin triggered resolvin E biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Ovarian steroidogenesis
Toxoplasmosis
NetPath Pathway IL4 Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 529646J Med Chem. 2008 Sep 11;51(17):5449-53. Epub 2008 Aug 19.Novel and potent inhibitors of 5-lipoxygenase product synthesis based on the structure of pirinixic acid.
Ref 529646J Med Chem. 2008 Sep 11;51(17):5449-53. Epub 2008 Aug 19.Novel and potent inhibitors of 5-lipoxygenase product synthesis based on the structure of pirinixic acid.

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