Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03IUY
|
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| Former ID |
DIB007359
|
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| Drug Name |
Estropipate
|
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| Drug Type |
Small molecular drug
|
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| Indication | Hypogonadism [ICD9: 257.2; ICD10:E23.0, E28.3, E29.1] | Approved | [551871] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C22H32N2O5S
|
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| Canonical SMILES |
C[C@]12CC[C@H]3[C@@H](CCc4cc(OS(=O)(=O)O)ccc34)[C@@H]1C<br />CC2=O.C5CNCCN5
|
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| InChI |
1S/C18H22O5S.C4H10N2/c1-18-9-8-14-13-5-3-12(23-24(20,21)22)10-11(13)2-4-15(14)16(18)6-7-17(18)19;1-2-6-4-3-5-1/h3,5,10,14-16H,2,4,6-9H2,1H3,(H,20,21,22);5-6H,1-4H2/t14-,15-,16+,18+;/m1./s1
|
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| InChIKey |
HZEQBCVBILBTEP-ZFINNJDLSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Estrogen receptor | Target Info | Modulator | [550912], [551871] | |
| Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
| Signaling events mediated by HDAC Class II | |||||
| Plasma membrane estrogen receptor signaling | |||||
| LKB1 signaling events | |||||
| Regulation of Telomerase | |||||
| ATF-2 transcription factor network | |||||
| AP-1 transcription factor network | |||||
| FOXM1 transcription factor network | |||||
| Validated nuclear estrogen receptor alpha network | |||||
| Signaling mediated by p38-alpha and p38-beta | |||||
| FOXA1 transcription factor network | |||||
| References | |||||
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