Drug Information

Drug General Information
Drug ID
D03SKD
Former ID
DAP000283
Drug Name
Oxycodone
Synonyms
Combunox; Dihydrohydroxycodeinone; Dihydrohydroxycondeinone; Dihydrone; Dihydroxycodeinone; Dinarkon; Diphydrone; Endone; Eubine; Eucodal; Eucodalum; Hydroxycodeinon; Ossicodone; Oxanest; Oxicodona; Oxicon; Oxicone; Oxiconum; OxyIR; Oxycodeinon; Oxycodeinone; Oxycodon; Oxycodonum; Oxycone; Oxycontin; Oxyfast; Oxynorm; Pancodine; Percobarb; Percodan; Percolone; Remoxy; Roxicet; Roxicodone; Supendol; Supeudol; Theocodin; Eubine [France]; Ossicodone [DCIT]; Oxycodone Concentrate; Oxycodone Hcl; Oxycodone hydrochloride; Supendol [Canada]; Combunox (TN); Endine (Australia); Endocet (TN); Endodan (TN); Oxicodona [INN-Spanish]; OxyContin (TN); Oxycodonum [INN-Latin]; PTI-821; Pancodone retard (United Kingdom); Percocet (TN); Percodan (TN); Roxicet (TN); Roxiprin (TN); Tekodin (free base); Tylox (TN); Dihydro-14-hydroxycodeinone; Oxycodone (USAN/INN); Oxycodone [USAN:INN:BAN]; Morphinan-6-one, 4,5alpha-epoxy-14-hydroxy-3-methoxy-17-methyl-(8CI); (-)-14-Hydroxydihydrocodeinone; (-)-Oxycodone; (5alpha)-14-hydroxy-17-methyl-3-(methyloxy)-4,5-epoxymorphinan-6-one; 14-Hydroxydihydrocodeinone; 14-hydroxy-3-methoxy-17-methyl-4,5alpha-epoxymorphinan-6-one; 4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one; 4,5.alpha.-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one; 4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
Drug Type
Small molecular drug
Indication Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] Approved [538359], [542099]
Therapeutic Class
Analgesics
Company
Watson Laboratories
Structure
Download
2D MOL

3D MOL
Formula
C18H21NO4
InChI
InChI=1S/C18H21NO4/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10/h3-4,13,16,21H,5-9H2,1-2H3/t13-,16+,17+,18-/m1/s1
InChIKey
BRUQQQPBMZOVGD-XFKAJCMBSA-N
CAS Number
CAS 76-42-6
PubChem Compound ID
5284603
PubChem Substance ID
10218, 81987, 7980232, 11039373, 14825887, 14923583, 16697449, 39317907, 46508908, 47207011, 48416366, 49993158, 50887162, 56464157, 85242752, 92714668, 103189261, 104133805, 117497014, 126629457, 127559039, 134222776, 134337597, 135269853, 137001259, 139157519, 152101652, 160849697, 160963843, 162224649, 175266292, 178103671, 179116835, 184548425, 223656812, 223800482, 226395100
ChEBI ID
ChEBI:7852
SuperDrug ATC ID
N02AA05
SuperDrug CAS ID
cas=000076426
Target and Pathway
Target(s) Delta-type opioid receptor Target Info Agonist [536427]
KEGG Pathway cGMP-PKG signaling pathway
Sphingolipid signaling pathway
Neuroactive ligand-receptor interaction
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Enkephalin release
Opioid proenkephalin pathway
Opioid proopiomelanocortin pathway
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 538359FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 085910.
Ref 542099(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7093).
Ref 536427Oxycodone: a pharmacological and clinical review. Clin Transl Oncol. 2007 May;9(5):298-307.

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