Drug Information

Drug General Information
Drug ID
D04ZTY
Former ID
DAP001104
Drug Name
Voglibose
Synonyms
Basen; Glustat; Vocarb; Basen OD; A-71100; AO-128; Basen (TN); Basen (Takeda Chemical Industries); Volix (Ranbaxy labs);Voglibose (JP15/USAN/INN); N-(1,3-Dihydroxyprop-2-yl)valiolamine; (1S,2S,3R,4S,5S)-5-(1,3-dihydroxypropan-2-ylamino)-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol; (1S,2S,3R,4S,5S)-5-{[2-hydroxy-1-(hydroxymethyl)ethyl]amino}-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol; 3,4-Dideoxy-4-{[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-2-D-epi-inositol
Drug Type
Small molecular drug
Indication Diabetes [ICD9: 253.5, 588.1; ICD10:E23.2, N25.1] Approved [536361]
Therapeutic Class
Hypoglycemic Agents
Company
Takeda
Structure
Download
2D MOL

3D MOL
Formula
C10H21NO7
Canonical SMILES
C1C(C(C(C(C1(CO)O)O)O)O)NC(CO)CO
InChI
1S/C10H21NO7/c12-2-5(3-13)11-6-1-10(18,4-14)9(17)8(16)7(6)15/h5-9,11-18H,1-4H2/t6-,7-,8+,9-,10-/m0/s1
InChIKey
FZNCGRZWXLXZSZ-CIQUZCHMSA-N
CAS Number
CAS 83480-29-9
PubChem Compound ID
444020
PubChem Substance ID
7848728, 10299466, 12013776, 15070756, 36887136, 46504462, 48414634, 49835305, 57404590, 80611090, 103624146, 104111539, 104631150, 119525753, 121264490, 126592896, 134223911, 134338349, 135027174, 135812317, 136367734, 136948052, 137002784, 139694698, 144205773, 152090258, 152344538, 160967826, 164178111, 164814716, 170465993, 179151268, 184545240, 198946321, 210279172, 210281495, 226397450, 241164518, 249726430, 251915707, 251917057, 252157387, 252216589, 252359063, 252451111
SuperDrug ATC ID
A10BF03
SuperDrug CAS ID
cas=083480299
Target and Pathway
Target(s) Maltase-glucoamylase, intestinal Target Info Inhibitor [537567]
KEGG Pathway Galactose metabolism
Starch and sucrose metabolism
Metabolic pathways
Carbohydrate digestion and absorption
PathWhiz Pathway Starch and Sucrose Metabolism
WikiPathways Metabolism of carbohydrates
References
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.
Ref 537567Effects of changeover from voglibose to acarbose on postprandial triglycerides in type 2 diabetes mellitus patients. Adv Ther. 2009 Jun;26(6):660-6. Epub 2009 Jun 30.

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