Drug Information

Drug General Information
Drug ID
D08MUX
Former ID
DNC002363
Drug Name
S33005
Drug Type
Small molecular drug
Indication Depression [ICD9: 311; ICD10:F30-F39] Investigative [536286]
Therapeutic Class
Psychiatric
Company
Servier
Structure
Download
2D MOL

3D MOL
Formula
C18H27NO2
Canonical SMILES
CN(C)CC1(CC2=C1C=C(C=C2)OC)C3(CCCCC3)O
InChI
1S/C18H27NO2/c1-19(2)13-17(18(20)9-5-4-6-10-18)12-14-7-8-15(21-3)11-16(14)17/h7-8,11,20H,4-6,9-10,12-13H2,1-3H3
InChIKey
UBIQMAFTTDZGEX-UHFFFAOYSA-N
PubChem Compound ID
9925999
PubChem Substance ID
14897957, 24202429, 47285845, 47731237, 57309573, 77921059, 129344016, 136351905, 227206516
Target and Pathway
Target(s) Sodium-dependent serotonin transporter Target Info Inhibitor [536286]
Sodium-dependent noradrenaline transporter Target Info Inhibitor [536286]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway 5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathwayP00001:Adrenaline and noradrenaline biosynthesis
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
SIDS Susceptibility Pathways
NRF2 pathway
Synaptic Vesicle Pathway
Serotonin Transporter ActivityWP727:Monoamine Transport
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
References
Ref 536286Serotonin reuptake inhibitors: the corner stone in treatment of depression for half a century--a medicinal chemistry survey. Curr Top Med Chem. 2006;6(17):1801-23.
Ref 536286Serotonin reuptake inhibitors: the corner stone in treatment of depression for half a century--a medicinal chemistry survey. Curr Top Med Chem. 2006;6(17):1801-23.

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