Drug Information

Drug General Information
Drug ID
D08OUU
Former ID
DIB013260
Drug Name
Genevx
Synonyms
Ad5-VEGF145; Restenosis therapy, Collateral; VEGF gene therapy, Collateral
Indication Angina pectoris [ICD9: 413; ICD10:I20] Terminated [547116]
Company
Collateral Therapeutics Inc
Target and Pathway
Target(s) VEGF receptor Target Info Modulator [549790]
KEGG Pathway Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
HIF-1 signaling pathway
Endocytosis
PI3K-Akt signaling pathway
Focal adhesion
Transcriptional misregulation in cancer
Rheumatoid arthritis
References
Ref 547116Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013170)
Ref 549790Vascular Endothelial Growth Factor Gene Therapy Increases Survival, Promotes Lung Angiogenesis, and Prevents Alveolar Damage in Hyperoxia-Induced Lung Injury. Circulation. 2005; 112: 2477-2486.

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