Drug Information
Drug General Information | |||||
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Drug ID |
D0AN7B
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Former ID |
DAP000429
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Drug Name |
Melatonin
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Synonyms |
Circadin; Melapure; Melatol; Melatonex; Melatonina; Melatonine; Melovine; Posidorm; Vivitas; Night Rest; Pineal Hormone; Revital Melatonin; Rx Balance; Sleep Right; IN1244; M 5250; M1105; ML1; MT6; TNP00300; M-1200; M-1250; Mela-T; Melatonex, Melatonin; Melatonina (TN); NMR/14327425; Nature'S Harmony; PREVENTION 2 (MELATONIN); PREVENTION 3 (MELATONIN); PREVENTION 4 (MELATONIN); PREVENTION 5 (MELATONIN); PREVENTION 1 (MELATONIN) (PREVENTION 1); N-Acetyl-5-methoxytryptamine; N-acetyl-5-methoxy-tryptamine; N-[2-(5-methoxyindol-3-yl)ethyl]acetamide; N-(2-(5-Methoxyindol-3-yl)ethyl)acetamide; N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide; Acetamide, {N-[2-(5-methoxyindol-3-yl)ethyl]-}; N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide; Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]-(6CI,8CI); N-[2-(5-Methoxy-1H-indol-3-yl)-ethyl]-acetamide; Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-(9CI); Acetamide, {N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-}; Acetamide, N-(2-(5-methoxy-1H-indol-3-yl)ethyl)-(9CI); 4-ACETAMIDO-4'-ISOTHIO-CYANATOSTILBENE-2,2'-DISULFONIC ACID; 5-Methoxy-N-acetyltryptamine
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Drug Type |
Small molecular drug
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Therapeutic Class |
Central Nervous System Stimulants
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Structure |
Download2D MOL |
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Formula |
C13H16N2O2
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InChI |
InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)
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InChIKey |
DRLFMBDRBRZALE-UHFFFAOYSA-N
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CAS Number |
CAS 73-31-4
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PubChem Compound ID | |||||
PubChem Substance ID |
2961, 4752, 105815, 410775, 798411, 841969, 893664, 3133753, 4906256, 7636333, 7961516, 7979886, 8144655, 8149639, 8150851, 10321385, 10534170, 10589869, 11111467, 11111468, 11111469, 11221066, 11335528, 11360767, 11363079, 11365641, 11368203, 11372325, 11373730, 11376365, 11408768, 11461739, 11466486, 11467606, 11485263, 11486211, 11489160, 11491208, 11491881, 11493999, 11536797, 11537588, 14773848, 17388930, 17389536, 17405348, 24278103, 24439254, 26612030, 26679682
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ChEBI ID |
ChEBI:16796
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SuperDrug ATC ID |
N05CH01
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SuperDrug CAS ID |
cas=000073314
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Target and Pathway | |||||
Target(s) | Melatonin receptor | Target Info | Binder | [536063], [536104] | |
References | |||||
Ref 537181 | Melatonin and melatonergic drugs on sleep: possible mechanisms of action. Int J Neurosci. 2009;119(6):821-46. | ||||
Ref 539417 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 224). | ||||
Ref 551871 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | ||||
Ref 536063 | The human MT1 melatonin receptor stimulates cAMP production in the human neuroblastoma cell line SH-SY5Y cells via a calcium-calmodulin signal transduction pathway. J Neuroendocrinol. 2005 Mar;17(3):170-8. | ||||
Ref 536104 | Coexpression of MT1 and RORalpha1 melatonin receptors in the Syrian hamster Harderian gland. J Pineal Res. 2005 Aug;39(1):21-6. |
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