Drug Information

Drug General Information
Drug ID
D0BT1A
Former ID
DIB018576
Drug Name
2-pyridylethylamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538708]
Structure
Download
2D MOL
Formula
C7H10N2
InChI
InChI=1S/C7H10N2/c8-5-4-7-3-1-2-6-9-7/h1-3,6H,4-5,8H2
InChIKey
XPQIPUZPSLAZDV-UHFFFAOYSA-N
PubChem Compound ID
75919
PubChem Substance ID
114838, 3131926, 4760914, 8139935, 8197638, 10516442, 15194427, 24890987, 29215556, 33239118, 43131639, 46386941, 47217226, 47885859, 48415388, 49681778, 49846679, 50068746, 51072144, 57319844, 57566665, 57641336, 80200244, 84974739, 85173768, 85177265, 85208914, 85787663, 87559237, 87691264, 88809650, 92136720, 92308472, 92714356, 103122164, 103207571, 104362959, 104668887, 117521967, 117531357, 117531392, 117651842, 117687086, 118284203, 121280609, 124659053, 125346668, 126588407, 126610912, 126624200
Target and Pathway
Target(s) Histamine H1 receptor Target Info Agonist [527113]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
PANTHER Pathway Histamine H1 receptor mediated signaling pathway
Reactome Histamine receptors
G alpha (q) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
IL-4 Signaling Pathway
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 538708(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1197).
Ref 527113Large-scale overproduction, functional purification and ligand affinities of the His-tagged human histamine H1 receptor. Eur J Biochem. 2004 Jul;271(13):2636-46.

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