Drug General Information
Drug ID	D0LL4C
Former ID	DNC001448
Drug Name	TIP
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[534987]
Structure		Download 2D MOL 3D MOL
Formula	O-2
Canonical SMILES	[O-2]
InChI	1S/O/q-2
InChIKey	AHKZTVQIVOEVFO-UHFFFAOYSA-N
CAS Number	CAS 88149-94-4
PubChem Compound ID	190217
PubChem Substance ID	7887223, 7890784, 10261150, 11534160, 14842769, 33511569, 57396438, 75980933, 103843696, 113447953, 117385022, 134340630, 135169214, 142459773, 162801284
Target and Pathway
Target(s)	Delta-type opioid receptor	Target Info	Antagonist	[534987]
KEGG Pathway	cGMP-PKG signaling pathway
	Sphingolipid signaling pathway
	Neuroactive ligand-receptor interaction
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
	Enkephalin release
	Opioid proenkephalin pathway
	Opioid proopiomelanocortin pathway
Reactome	Peptide ligand-binding receptors
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 534987	The TIPP opioid peptide family: development of delta antagonists, delta agonists, and mixed mu agonist/delta antagonists. Biopolymers. 1999;51(6):411-25.
Ref 534987	The TIPP opioid peptide family: development of delta antagonists, delta agonists, and mixed mu agonist/delta antagonists. Biopolymers. 1999;51(6):411-25.

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