Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0O7GU
|
||||
| Former ID |
DAP001026
|
||||
| Drug Name |
Palifermin
|
||||
| Synonyms |
Kepivance; Kepivance (TN); Palifermin (USAN/INN)
|
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| Therapeutic Class |
Antimucositis Agents
|
||||
| Formula |
C721H1142N202O204S9
|
||||
| CAS Number |
CAS 162394-19-6
|
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| PubChem Substance ID | |||||
| SuperDrug ATC ID |
V03AF08
|
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| Target and Pathway | |||||
| Target(s) | Fibroblast growth factor receptor 2 | Target Info | Binder | [537352] | |
| NetPath Pathway | IL1 Signaling Pathway | ||||
| PANTHER Pathway | FGF signaling pathway | ||||
| Pathway Interaction Database | FGF signaling pathway | ||||
| Reactome | Activated point mutants of FGFR2 | ||||
| WikiPathways | Regulation of Actin Cytoskeleton | ||||
| Ectoderm Differentiation | |||||
| Hair Follicle Development: Organogenesis (Part 2 of 3) | |||||
| Hair Follicle Development: Induction (Part 1 of 3) | |||||
| Cardiac Hypertrophic Response | |||||
| Signaling Pathways in Glioblastoma | |||||
| Neural Crest Differentiation | |||||
| Signaling by FGFR | |||||
| MicroRNAs in cardiomyocyte hypertrophy | |||||
| Angiogenesis | |||||
| References | |||||
| Ref 536838 | Emerging drugs for chemotherapy-induced mucositis. Expert Opin Emerg Drugs. 2008 Sep;13(3):511-22. | ||||
| Ref 541990 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6954). | ||||
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