Drug General Information
Drug ID
D0SY2M
Former ID
DIB019692
Drug Name
daidzein
Synonyms
7,4'-dihydroxyisoflavone
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527027]
Structure
Download
2D MOL

3D MOL

Formula
C15H10O4
InChI
InChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)13-8-19-14-7-11(17)5-6-12(14)15(13)18/h1-8,16-17H
InChIKey
ZQSIJRDFPHDXIC-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) TRP cation channel C5 Target Info Activator [543854]
Estrogen-related receptor-gamma Target Info Agonist [526891]
Estrogen-related receptor-beta Target Info Agonist [526891]
Steroid hormone receptor ERR1 Target Info Agonist [526891]
PANTHER Pathway Alzheimer disease-presenilin pathway
Reactome TRP channels
Role of second messengers in netrin-1 signalingR-HSA-1989781:PPARA activates gene expression
Transcriptional activation of mitochondrial biogenesis
Nuclear Receptor transcription pathway
WikiPathways Netrin-1 signalingWP391:Mitochondrial Gene Expression
Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Nuclear Receptors
References
Ref 527027The balance between concurrent activation of ERs and PPARs determines daidzein-induced osteogenesis and adipogenesis. J Bone Miner Res. 2004 May;19(5):853-61. Epub 2004 Jan 19.
Ref 526891Flavone and isoflavone phytoestrogens are agonists of estrogen-related receptors. Mol Cancer Res. 2003 Nov;1(13):981-91.
Ref 543854(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 490).

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.